메뉴 건너뛰기




Volumn 67, Issue 1, 2010, Pages 34-38

The neuroendocrine physiology of female reproductive aging: An update

Author keywords

Female; Menopause; Neuroendocrine; Reproduction; Senescence

Indexed keywords

ESTROGEN; FOLLITROPIN; GLUTAMIC ACID; GONADORELIN; INHIBIN B; KISSPEPTIN; LUTEINIZING HORMONE; NORADRENALIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 77955921961     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2010.04.016     Document Type: Review
Times cited : (47)

References (76)
  • 1
    • 34548329615 scopus 로고    scopus 로고
    • Neuroendocrine changes with reproductive aging in women
    • J.E. Hall Neuroendocrine changes with reproductive aging in women Semin Reprod Med 25 5 2007 344 351
    • (2007) Semin Reprod Med , vol.25 , Issue.5 , pp. 344-351
    • Hall, J.E.1
  • 2
    • 15244350751 scopus 로고    scopus 로고
    • The aging reproductive neuroendocrine axis
    • D.W. Brann, and V.B. Mahesh The aging reproductive neuroendocrine axis Steroids 70 4 2005 273 283
    • (2005) Steroids , vol.70 , Issue.4 , pp. 273-283
    • Brann, D.W.1    Mahesh, V.B.2
  • 3
    • 0029863560 scopus 로고    scopus 로고
    • Reproductive aging: Accelerated ovarian follicular development associated with a monotropic follicle-stimulating hormone rise in normal older women
    • N.A. Klein, D.E. Battaglia, and V.Y. Fujimoto Reproductive aging: accelerated ovarian follicular development associated with a monotropic follicle-stimulating hormone rise in normal older women J Clin Endocrinol Metab 81 3 1996 1038 1045
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.3 , pp. 1038-1045
    • Klein, N.A.1    Battaglia, D.E.2    Fujimoto, V.Y.3
  • 4
    • 28944452155 scopus 로고    scopus 로고
    • Ovarian aging and menopause: Current theories, hypotheses, and research models
    • J.M. Wu, M.B. Zelinski, D.K. Ingram, and M.A. Ottinger Ovarian aging and menopause: current theories, hypotheses, and research models Exp Biol Med (Maywood) 230 11 2005 818 828
    • (2005) Exp Biol Med (Maywood) , vol.230 , Issue.11 , pp. 818-828
    • Wu, J.M.1    Zelinski, M.B.2    Ingram, D.K.3    Ottinger, M.A.4
  • 5
    • 0036364349 scopus 로고    scopus 로고
    • Neuroendocrine modulation and repercussions of female reproductive aging
    • P.M. Wise, M.J. Smith, and D.B. Dubal Neuroendocrine modulation and repercussions of female reproductive aging Recent Prog Horm Res 57 2002 235 256
    • (2002) Recent Prog Horm Res , vol.57 , pp. 235-256
    • Wise, P.M.1    Smith, M.J.2    Dubal, D.B.3
  • 6
    • 0035076504 scopus 로고    scopus 로고
    • Influences of age and ovarian follicular reserve on estrous cycle patterns, ovulation, and hormone secretion in the Long-Evans rat
    • C.R. Anzalone, L.S. Hong, J.K. Lu, and P.S. LaPolt Influences of age and ovarian follicular reserve on estrous cycle patterns, ovulation, and hormone secretion in the Long-Evans rat Biol Reprod 64 4 2001 1056 1062
    • (2001) Biol Reprod , vol.64 , Issue.4 , pp. 1056-1062
    • Anzalone, C.R.1    Hong, L.S.2    Lu, J.K.3    Lapolt, P.S.4
  • 7
    • 0029923588 scopus 로고    scopus 로고
    • Characterization of inhibin immunoreactivity in post-menopausal women with ovarian tumours
    • H.G. Burger, D.M. Robertson, and N. Cahir Characterization of inhibin immunoreactivity in post-menopausal women with ovarian tumours Clin Endocrinol (Oxf) 44 4 1996 413 418
    • (1996) Clin Endocrinol (Oxf) , vol.44 , Issue.4 , pp. 413-418
    • Burger, H.G.1    Robertson, D.M.2    Cahir, N.3
  • 8
    • 0019132995 scopus 로고
    • Characterization of the LH surge in middle-aged female rats
    • R.L. Cooper, P.M. Conn, and R.F. Walker Characterization of the LH surge in middle-aged female rats Biol Reprod 23 3 1980 611 615
    • (1980) Biol Reprod , vol.23 , Issue.3 , pp. 611-615
    • Cooper, R.L.1    Conn, P.M.2    Walker, R.F.3
  • 9
    • 0029835606 scopus 로고    scopus 로고
    • Hot flushes, menstrual status, and hormone levels in a population-based sample of midlife women
    • J.R. Guthrie, L. Dennerstein, J.L. Hopper, and H.G. Burger Hot flushes, menstrual status, and hormone levels in a population-based sample of midlife women Obstet Gynecol 88 3 1996 437 442
    • (1996) Obstet Gynecol , vol.88 , Issue.3 , pp. 437-442
    • Guthrie, J.R.1    Dennerstein, L.2    Hopper, J.L.3    Burger, H.G.4
  • 10
    • 0031957355 scopus 로고    scopus 로고
    • Effects of aging and gonadal failure on the hypothalamic-pituitary axis in women
    • N. Santoro, T. Banwell, and D. Tortoriello Effects of aging and gonadal failure on the hypothalamic-pituitary axis in women Am J Obstet Gynecol 178 4 1998 732 741
    • (1998) Am J Obstet Gynecol , vol.178 , Issue.4 , pp. 732-741
    • Santoro, N.1    Banwell, T.2    Tortoriello, D.3
  • 11
    • 10844232033 scopus 로고    scopus 로고
    • Menopause and hypothalamic-pituitary sensitivity to estrogen
    • G. Weiss, J.H. Skurnick, L.T. Goldsmith, N.F. Santoro, and S.J. Park Menopause and hypothalamic-pituitary sensitivity to estrogen JAMA 292 24 2004 2991 2996
    • (2004) JAMA , vol.292 , Issue.24 , pp. 2991-2996
    • Weiss, G.1    Skurnick, J.H.2    Goldsmith, L.T.3    Santoro, N.F.4    Park, S.J.5
  • 12
    • 51649122067 scopus 로고    scopus 로고
    • Aging and hormones of the hypothalamo-pituitary axis: Gonadotropic axis in men and somatotropic axes in men and women
    • J.D. Veldhuis Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women Ageing Res Rev 7 3 2008 189 208
    • (2008) Ageing Res Rev , vol.7 , Issue.3 , pp. 189-208
    • Veldhuis, J.D.1
  • 13
    • 58349093290 scopus 로고    scopus 로고
    • The role of the brain in female reproductive aging
    • J.L. Downs, and P.M. Wise The role of the brain in female reproductive aging Mol Cell Endocrinol 299 1 2009 32 38
    • (2009) Mol Cell Endocrinol , vol.299 , Issue.1 , pp. 32-38
    • Downs, J.L.1    Wise, P.M.2
  • 14
    • 0025780374 scopus 로고
    • Endogenous excitatory amino acid involvement in the preovulatory and steroid-induced surge of gonadotropins in the female rat
    • D. Brann, and V. Mahesh Endogenous excitatory amino acid involvement in the preovulatory and steroid-induced surge of gonadotropins in the female rat Endocrinology 128 3 1991 1541 1547
    • (1991) Endocrinology , vol.128 , Issue.3 , pp. 1541-1547
    • Brann, D.1    Mahesh, V.2
  • 15
    • 24944487970 scopus 로고    scopus 로고
    • Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats
    • G.S. Neal-Perry, G.D. Zeevalk, N.F. Santoro, and A.M. Etgen Attenuation of preoptic area glutamate release correlates with reduced luteinizing hormone secretion in middle-aged female rats Endocrinology 146 10 2005 4331 4339
    • (2005) Endocrinology , vol.146 , Issue.10 , pp. 4331-4339
    • Neal-Perry, G.S.1    Zeevalk, G.D.2    Santoro, N.F.3    Etgen, A.M.4
  • 16
    • 0028179180 scopus 로고
    • Release of glutamate and aspartate from the preoptic area during the progesterone-induced LH surge: In vivo microdialysis studies
    • L. Ping, V.B. Mahesh, V.T. Wiedmeier, and D.W. Brann Release of glutamate and aspartate from the preoptic area during the progesterone-induced LH surge: in vivo microdialysis studies Neuroendocrinology 59 4 1994 318 324
    • (1994) Neuroendocrinology , vol.59 , Issue.4 , pp. 318-324
    • Ping, L.1    Mahesh, V.B.2    Wiedmeier, V.T.3    Brann, D.W.4
  • 17
    • 35948986402 scopus 로고    scopus 로고
    • The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone
    • H.M. Dungan, M.L. Gottsch, and H. Zeng The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone J Neurosci 27 44 2007 12088 12095
    • (2007) J Neurosci , vol.27 , Issue.44 , pp. 12088-12095
    • Dungan, H.M.1    Gottsch, M.L.2    Zeng, H.3
  • 18
    • 24944432237 scopus 로고    scopus 로고
    • Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats
    • M. Kinoshita, H. Tsukamura, and S. Adachi Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats Endocrinology 146 10 2005 4431 4436
    • (2005) Endocrinology , vol.146 , Issue.10 , pp. 4431-4436
    • Kinoshita, M.1    Tsukamura, H.2    Adachi, S.3
  • 19
    • 0027428642 scopus 로고
    • Effects of N-methyl-d-aspartate receptor activation on cFos expression in luteinizing hormone-releasing hormone neurons in female rats
    • W.S. Lee, R. Abbud, G.E. Hoffman, and M.S. Smith Effects of N-methyl-d-aspartate receptor activation on cFos expression in luteinizing hormone-releasing hormone neurons in female rats Endocrinology 133 5 1993 2248 2254
    • (1993) Endocrinology , vol.133 , Issue.5 , pp. 2248-2254
    • Lee, W.S.1    Abbud, R.2    Hoffman, G.E.3    Smith, M.S.4
  • 20
    • 0026554590 scopus 로고
    • Interaction between ovarian and adrenal steroids in the regulation of gonadotropin secretion
    • V.B. Mahesh, and D.W. Brann Interaction between ovarian and adrenal steroids in the regulation of gonadotropin secretion J Steroid Biochem Mol Biol 41 3-8 1992 495 513
    • (1992) J Steroid Biochem Mol Biol , vol.41 , Issue.38 , pp. 495-513
    • Mahesh, V.B.1    Brann, D.W.2
  • 21
    • 0021116261 scopus 로고
    • Hypothalamic adrenergic activity precedes the preovulatory luteinizing hormone surge in the rat
    • P.C. MacKinnon, E.M. Clement, C. Clark, and R. Sheaves Hypothalamic adrenergic activity precedes the preovulatory luteinizing hormone surge in the rat Neurosci Lett 43 2-3 1983 221 226
    • (1983) Neurosci Lett , vol.43 , Issue.2-3 , pp. 221-226
    • MacKinnon, P.C.1    Clement, E.M.2    Clark, C.3    Sheaves, R.4
  • 22
    • 0028356370 scopus 로고
    • Correlations of catecholamine release in the medial preoptic area with proestrous surges of luteinizing hormone and prolactin: Effects of aging
    • P.S. Mohankumar, S. Thyagarajan, and S.K. Quadri Correlations of catecholamine release in the medial preoptic area with proestrous surges of luteinizing hormone and prolactin: effects of aging Endocrinology 135 1 1994 119 126
    • (1994) Endocrinology , vol.135 , Issue.1 , pp. 119-126
    • Mohankumar, P.S.1    Thyagarajan, S.2    Quadri, S.K.3
  • 23
    • 0032526420 scopus 로고    scopus 로고
    • Aging alters the rhythmic expression of vasoactive intestinal polypeptide mRNA but not arginine vasopressin mRNA in the suprachiasmatic nuclei of female rats
    • K. Krajnak, M.L. Kashon, K.L. Rosewell, and P.M. Wise Aging alters the rhythmic expression of vasoactive intestinal polypeptide mRNA but not arginine vasopressin mRNA in the suprachiasmatic nuclei of female rats J Neurosci 18 12 1998 4767 4774
    • (1998) J Neurosci , vol.18 , Issue.12 , pp. 4767-4774
    • Krajnak, K.1    Kashon, M.L.2    Rosewell, K.L.3    Wise, P.M.4
  • 24
    • 0028358067 scopus 로고
    • Preferential induction of c-fos immunoreactivity in vasoactive intestinal polypeptide-innervated gonadotropin-releasing hormone neurons during a steroid-induced luteinizing hormone surge in the female rat
    • E.M. van der Beek, H.J. van Oudheusden, and R.M. Buijs Preferential induction of c-fos immunoreactivity in vasoactive intestinal polypeptide-innervated gonadotropin-releasing hormone neurons during a steroid-induced luteinizing hormone surge in the female rat Endocrinology 134 6 1994 2636 2644
    • (1994) Endocrinology , vol.134 , Issue.6 , pp. 2636-2644
    • Van Der Beek, E.M.1    Van Oudheusden, H.J.2    Buijs, R.M.3
  • 26
    • 0029591616 scopus 로고
    • Regulation of GABA transporter activity and mRNA expression by estrogen in rat preoptic area
    • A.E. Herbison, S.J. Augood, S.X. Simonian, and C. Chapman Regulation of GABA transporter activity and mRNA expression by estrogen in rat preoptic area J Neurosci 15 12 1995 8302 8309
    • (1995) J Neurosci , vol.15 , Issue.12 , pp. 8302-8309
    • Herbison, A.E.1    Augood, S.J.2    Simonian, S.X.3    Chapman, C.4
  • 27
    • 0027319910 scopus 로고
    • Effects of gamma-aminobutyric acid-A receptor antagonist, bicuculline, on the electrical activity of luteinizing hormone-releasing hormone pulse generator in the ovariectomized rat
    • F. Kimura, A. Sano, H. Hiruma, and T. Funabashi Effects of gamma-aminobutyric acid-A receptor antagonist, bicuculline, on the electrical activity of luteinizing hormone-releasing hormone pulse generator in the ovariectomized rat Neuroendocrinology 57 4 1993 605 614
    • (1993) Neuroendocrinology , vol.57 , Issue.4 , pp. 605-614
    • Kimura, F.1    Sano, A.2    Hiruma, H.3    Funabashi, T.4
  • 28
    • 55549126867 scopus 로고    scopus 로고
    • Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area
    • G.S. Neal-Perry, G.D. Zeevalk, J. Shu, and A.M. Etgen Restoration of the luteinizing hormone surge in middle-aged female rats by altering the balance of GABA and glutamate transmission in the medial preoptic area Biol Reprod 79 5 2008 878 888
    • (2008) Biol Reprod , vol.79 , Issue.5 , pp. 878-888
    • Neal-Perry, G.S.1    Zeevalk, G.D.2    Shu, J.3    Etgen, A.M.4
  • 29
    • 0028990167 scopus 로고
    • Activation of central GABAA-but not of GABAB-receptors rapidly reduces pituitary LH release and GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized rats
    • S. Leonhardt, J.Y. Seong, and K. Kim Activation of central GABAA-but not of GABAB-receptors rapidly reduces pituitary LH release and GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized rats Neuroendocrinology 61 6 1995 655 662
    • (1995) Neuroendocrinology , vol.61 , Issue.6 , pp. 655-662
    • Leonhardt, S.1    Seong, J.Y.2    Kim, K.3
  • 30
    • 0003786006 scopus 로고
    • Results provided by heterochronic grafts of the ovaries in the study of the hypothalamo-hypophyso-ovarian regulation of Senile rats
    • P. Aschheim Results provided by heterochronic grafts of the ovaries in the study of the hypothalamo-hypophyso-ovarian regulation of Senile rats Gerontologia 10 1964 65 75
    • (1964) Gerontologia , vol.10 , pp. 65-75
    • Aschheim, P.1
  • 31
    • 0015383576 scopus 로고
    • Aging of hypothalamic-pituitary-ovarian function in the rat
    • M.T. Peng, and H.H. Huang Aging of hypothalamic-pituitary-ovarian function in the rat Fertil Steril 23 8 1972 535 542
    • (1972) Fertil Steril , vol.23 , Issue.8 , pp. 535-542
    • Peng, M.T.1    Huang, H.H.2
  • 32
    • 0020056007 scopus 로고
    • Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats
    • P.M. Wise Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats Proc Soc Exp Biol Med 169 3 1982 348 354
    • (1982) Proc Soc Exp Biol Med , vol.169 , Issue.3 , pp. 348-354
    • Wise, P.M.1
  • 33
    • 0028097227 scopus 로고
    • A reduced proportion of luteinizing hormone (LH)-releasing hormone neurons express Fos protein during the preovulatory or steroid-induced LH surge in middle-aged rats
    • B.S. Rubin, C.E. Lee, and J.C. King A reduced proportion of luteinizing hormone (LH)-releasing hormone neurons express Fos protein during the preovulatory or steroid-induced LH surge in middle-aged rats Biol Reprod 51 6 1994 1264 1272
    • (1994) Biol Reprod , vol.51 , Issue.6 , pp. 1264-1272
    • Rubin, B.S.1    Lee, C.E.2    King, J.C.3
  • 34
    • 67651151321 scopus 로고    scopus 로고
    • The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats
    • G. Neal-Perry, D. Lebesgue, and M. Lederman The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats Endocrinology 150 8 2009 3699 3708
    • (2009) Endocrinology , vol.150 , Issue.8 , pp. 3699-3708
    • Neal-Perry, G.1    Lebesgue, D.2    Lederman, M.3
  • 35
    • 77149173162 scopus 로고    scopus 로고
    • Hypothalamic insulin-like growth factor-i receptors are necessary for hormone-dependent luteinizing hormone surges: Implications for female reproductive aging
    • B.J. Todd, Z.O. Merhi, J. Shu, A.M. Etgen, and G.S. Neal-Perry Hypothalamic insulin-like growth factor-i receptors are necessary for hormone-dependent luteinizing hormone surges: implications for female reproductive aging Endocrinology 151 3 2010 Mar 1356 1366 Epub 2010 Jan 22
    • (2010) Endocrinology , vol.151 , Issue.3 , pp. 1356-1366
    • Todd, B.J.1    Merhi, Z.O.2    Shu, J.3    Etgen, A.M.4    Neal-Perry, G.S.5
  • 36
    • 0142126332 scopus 로고    scopus 로고
    • Stereologic analysis of estrogen receptor alpha (ER alpha) expression in rat hypothalamus and its regulation by aging and estrogen
    • T.R. Chakraborty, P.R. Hof, L. Ng, and A.C. Gore Stereologic analysis of estrogen receptor alpha (ER alpha) expression in rat hypothalamus and its regulation by aging and estrogen J Comp Neurol 466 3 2003 409 421
    • (2003) J Comp Neurol , vol.466 , Issue.3 , pp. 409-421
    • Chakraborty, T.R.1    Hof, P.R.2    Ng, L.3    Gore, A.C.4
  • 37
    • 0028694395 scopus 로고
    • Effects of estrogen and estrogen receptor messenger RNA levels in young and middle-aged female rats: Comparison of medial preoptic area and mediobasal hypothalamus
    • T. Funabashi, and F. Kimura Effects of estrogen and estrogen receptor messenger RNA levels in young and middle-aged female rats: comparison of medial preoptic area and mediobasal hypothalamus Acta Biol Hung 45 2-4 1994 223 231
    • (1994) Acta Biol Hung , vol.45 , Issue.2-4 , pp. 223-231
    • Funabashi, T.1    Kimura, F.2
  • 38
    • 0034281988 scopus 로고    scopus 로고
    • Changes in estrogenic regulation of estrogen receptor alpha mRNA and progesterone receptor mRNA in the female rat hypothalamus during aging: An in situ hybridization study
    • T. Funabashi, S.P. Kleopoulos, and P.J. Brooks Changes in estrogenic regulation of estrogen receptor alpha mRNA and progesterone receptor mRNA in the female rat hypothalamus during aging: an in situ hybridization study Neurosci Res 38 1 2000 85 92
    • (2000) Neurosci Res , vol.38 , Issue.1 , pp. 85-92
    • Funabashi, T.1    Kleopoulos, S.P.2    Brooks, P.J.3
  • 39
    • 0023017695 scopus 로고
    • Estrogen binding in nuclear and cytosolic extracts from brain and pituitary of middle-aged female rats
    • B.S. Rubin, T.O. Fox, and R.S. Bridges Estrogen binding in nuclear and cytosolic extracts from brain and pituitary of middle-aged female rats Brain Res 383 1-2 1986 60 67
    • (1986) Brain Res , vol.383 , Issue.1-2 , pp. 60-67
    • Rubin, B.S.1    Fox, T.O.2    Bridges, R.S.3
  • 40
    • 34249660014 scopus 로고    scopus 로고
    • Anterior pituitary gene expression with reproductive aging in the female rat
    • W. Zheng, M. Jimenez-Linan, B.S. Rubin, and L.M. Halvorson Anterior pituitary gene expression with reproductive aging in the female rat Biol Reprod 76 6 2007 1091 1102
    • (2007) Biol Reprod , vol.76 , Issue.6 , pp. 1091-1102
    • Zheng, W.1    Jimenez-Linan, M.2    Rubin, B.S.3    Halvorson, L.M.4
  • 41
    • 0022576614 scopus 로고
    • LHRH neurons in the female C57BL/6J mouse brain during reproductive aging: No loss up to middle age
    • G.E. Hoffman, and C.E. Finch LHRH neurons in the female C57BL/6J mouse brain during reproductive aging: no loss up to middle age Neurobiol Aging 7 1 1986 45 48
    • (1986) Neurobiol Aging , vol.7 , Issue.1 , pp. 45-48
    • Hoffman, G.E.1    Finch, C.E.2
  • 42
    • 0035081715 scopus 로고    scopus 로고
    • Fos-induction in gonadotropin-releasing hormone neurons receiving vasoactive intestinal polypeptide innervation is reduced in middle-aged female rats
    • K. Krajnak, K.L. Rosewell, and P.M. Wise Fos-induction in gonadotropin-releasing hormone neurons receiving vasoactive intestinal polypeptide innervation is reduced in middle-aged female rats Biol Reprod 64 4 2001 1160 1164
    • (2001) Biol Reprod , vol.64 , Issue.4 , pp. 1160-1164
    • Krajnak, K.1    Rosewell, K.L.2    Wise, P.M.3
  • 43
    • 0030813102 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone gene expression differs in young and middle-aged females on the day of a steroid-induced LH surge
    • B.S. Rubin, C.E. Lee, M. Ohtomo, and J.C. King Luteinizing hormone-releasing hormone gene expression differs in young and middle-aged females on the day of a steroid-induced LH surge Brain Res 770 1-2 1997 267 276
    • (1997) Brain Res , vol.770 , Issue.1-2 , pp. 267-276
    • Rubin, B.S.1    Lee, C.E.2    Ohtomo, M.3    King, J.C.4
  • 44
    • 0024580290 scopus 로고
    • Alterations in luteinizing hormone-releasing hormone release from the mediobasal hypothalamus of ovariectomized, steroid-primed middle-aged rats as measured by push-pull perfusion
    • B.S. Rubin, and R.S. Bridges Alterations in luteinizing hormone-releasing hormone release from the mediobasal hypothalamus of ovariectomized, steroid-primed middle-aged rats as measured by push-pull perfusion Neuroendocrinology 49 3 1989 225 232
    • (1989) Neuroendocrinology , vol.49 , Issue.3 , pp. 225-232
    • Rubin, B.S.1    Bridges, R.S.2
  • 45
    • 0034898523 scopus 로고    scopus 로고
    • Alterations in hypothalamic insulin-like growth factor-I and its associations with gonadotropin releasing hormone neurones during reproductive development and ageing
    • B.H. Miller, and A.C. Gore Alterations in hypothalamic insulin-like growth factor-I and its associations with gonadotropin releasing hormone neurones during reproductive development and ageing J Neuroendocrinol 13 8 2001 728 736
    • (2001) J Neuroendocrinol , vol.13 , Issue.8 , pp. 728-736
    • Miller, B.H.1    Gore, A.C.2
  • 46
    • 0034751111 scopus 로고    scopus 로고
    • Parallel declines in Fos activation of the medial anteroventral periventricular nucleus and LHRH neurons in middle-aged rats
    • W.-W. Le, P.M. Wise, A.Z. Murphy, L.M. Coolen, and G.E. Hoffman Parallel declines in Fos activation of the medial anteroventral periventricular nucleus and LHRH neurons in middle-aged rats Endocrinology 142 11 2001 4976 4982
    • (2001) Endocrinology , vol.142 , Issue.11 , pp. 4976-4982
    • Le, W.-W.1    Wise, P.M.2    Murphy, A.Z.3    Coolen, L.M.4    Hoffman, G.E.5
  • 47
    • 0026639445 scopus 로고
    • Isolated hypothalami from aging female rats do not exhibit reduced basal or potassium-stimulated secretion of luteinizing hormone-releasing hormone
    • B.S. Rubin Isolated hypothalami from aging female rats do not exhibit reduced basal or potassium-stimulated secretion of luteinizing hormone-releasing hormone Biol Reprod 47 2 1992 254 261
    • (1992) Biol Reprod , vol.47 , Issue.2 , pp. 254-261
    • Rubin, B.S.1
  • 48
    • 0033032531 scopus 로고    scopus 로고
    • Effects of age on GABA turnover rates in specific hypothalamic areas in female rats
    • H. Jarry, P.M. Wise, S. Leonhardt, and W. Wuttke Effects of age on GABA turnover rates in specific hypothalamic areas in female rats Exp Clin Endocrinol Diabetes 107 1 1999 59 62
    • (1999) Exp Clin Endocrinol Diabetes , vol.107 , Issue.1 , pp. 59-62
    • Jarry, H.1    Wise, P.M.2    Leonhardt, S.3    Wuttke, W.4
  • 49
    • 0026774982 scopus 로고
    • C-fos expression in noradrenergic A2 neurons of the rat during the estrous cycle and after steroid hormone treatments
    • L. Jennes, M.E. Jennes, C. Purvis, and M. Nees c-fos expression in noradrenergic A2 neurons of the rat during the estrous cycle and after steroid hormone treatments Brain Res 586 1 1992 171 175
    • (1992) Brain Res , vol.586 , Issue.1 , pp. 171-175
    • Jennes, L.1    Jennes, M.E.2    Purvis, C.3    Nees, M.4
  • 50
    • 34548569387 scopus 로고    scopus 로고
    • Middle-aged female rats lack the dynamic changes in GAD(67) mRNA levels observed in young females on the day of a luteinising hormone surge
    • D. Grove-Strawser, M. Jimenez-Linan, and B.S. Rubin Middle-aged female rats lack the dynamic changes in GAD(67) mRNA levels observed in young females on the day of a luteinising hormone surge J Neuroendocrinol 19 9 2007 708 716
    • (2007) J Neuroendocrinol , vol.19 , Issue.9 , pp. 708-716
    • Grove-Strawser, D.1    Jimenez-Linan, M.2    Rubin, B.S.3
  • 51
    • 0030592747 scopus 로고    scopus 로고
    • Effects of aging on N-methyl-d-aspartate (NMDA)-induced GnRH and LH release in female rats
    • P. Arias, S. Carbone, and B. Szwarcfarb Effects of aging on N-methyl-d-aspartate (NMDA)-induced GnRH and LH release in female rats Brain Res 740 1-2 1996 234 238
    • (1996) Brain Res , vol.740 , Issue.1-2 , pp. 234-238
    • Arias, P.1    Carbone, S.2    Szwarcfarb, B.3
  • 52
    • 0036720582 scopus 로고    scopus 로고
    • N-Methyl-d-aspartate receptor subunit expression in GnRH neurons changes during reproductive senescence in the female rat
    • B.H. Miller, and A.C. Gore N-Methyl-d-aspartate receptor subunit expression in GnRH neurons changes during reproductive senescence in the female rat Endocrinology 143 9 2002 3568 3574
    • (2002) Endocrinology , vol.143 , Issue.9 , pp. 3568-3574
    • Miller, B.H.1    Gore, A.C.2
  • 53
    • 70349798594 scopus 로고    scopus 로고
    • Three-dimensional properties of GnRH neuroterminals in the median eminence of young and old rats
    • W. Yin, J.M. Mendenhall, M. Monita, and A.C. Gore Three-dimensional properties of GnRH neuroterminals in the median eminence of young and old rats J Comp Neurol 517 3 2009 284 295
    • (2009) J Comp Neurol , vol.517 , Issue.3 , pp. 284-295
    • Yin, W.1    Mendenhall, J.M.2    Monita, M.3    Gore, A.C.4
  • 54
    • 4444317631 scopus 로고    scopus 로고
    • Aging alters norepinephrine release in the medial preoptic area in response to steroid priming in ovariectomized rats
    • S.M. MohanKumar, and P.S. MohanKumar Aging alters norepinephrine release in the medial preoptic area in response to steroid priming in ovariectomized rats Brain Res 1023 1 2004 24 30
    • (2004) Brain Res , vol.1023 , Issue.1 , pp. 24-30
    • Mohankumar, S.M.1    Mohankumar, P.S.2
  • 55
    • 0020446941 scopus 로고
    • Norepinephrine and dopamine activity in microdissected brain areas of the middle-aged and young rat on proestrus
    • P.M. Wise Norepinephrine and dopamine activity in microdissected brain areas of the middle-aged and young rat on proestrus Biol Reprod 27 3 1982 562 574
    • (1982) Biol Reprod , vol.27 , Issue.3 , pp. 562-574
    • Wise, P.M.1
  • 56
    • 0031732669 scopus 로고    scopus 로고
    • Absence of increased neuropeptide y neuronal activity before and during the luteinizing hormone (LH) surge may underlie the attenuated preovulatory LH surge in middle-aged rats
    • A. Sahu, and S.P. Kalra Absence of increased neuropeptide Y neuronal activity before and during the luteinizing hormone (LH) surge may underlie the attenuated preovulatory LH surge in middle-aged rats Endocrinology 139 2 1998 696 702
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 696-702
    • Sahu, A.1    Kalra, S.P.2
  • 57
    • 0022645572 scopus 로고
    • Evidence for gamma-aminobutyric acid modulation of ovarian hormonal effects on luteinizing hormone secretion and hypothalamic catecholamine activity in the female rat
    • B.A. Adler, and W.R. Crowley Evidence for gamma-aminobutyric acid modulation of ovarian hormonal effects on luteinizing hormone secretion and hypothalamic catecholamine activity in the female rat Endocrinology 118 1 1986 91 97
    • (1986) Endocrinology , vol.118 , Issue.1 , pp. 91-97
    • Adler, B.A.1    Crowley, W.R.2
  • 58
    • 17044420428 scopus 로고    scopus 로고
    • Age-related effects of IGF-1 on the NMDA-, GH- and IGF-1-receptor mRNA transcripts in the rat hippocampus
    • M. Le Greves, P. Le Greves, and F. Nyberg Age-related effects of IGF-1 on the NMDA-, GH- and IGF-1-receptor mRNA transcripts in the rat hippocampus Brain Res Bull 65 5 2005 369 374
    • (2005) Brain Res Bull , vol.65 , Issue.5 , pp. 369-374
    • Le Greves, M.1    Le Greves, P.2    Nyberg, F.3
  • 59
    • 0034004876 scopus 로고    scopus 로고
    • Age and insulin-like growth factor-1 modulate N-methyl-d-aspartate receptor subtype expression in rats
    • W.E. Sonntag, S.A. Bennett, and A.S. Khan Age and insulin-like growth factor-1 modulate N-methyl-d-aspartate receptor subtype expression in rats Brain Res Bull 51 4 2000 331 338
    • (2000) Brain Res Bull , vol.51 , Issue.4 , pp. 331-338
    • Sonntag, W.E.1    Bennett, S.A.2    Khan, A.S.3
  • 60
    • 58149473441 scopus 로고    scopus 로고
    • Insulin-like growth factor-I activates KiSS-1 gene expression in the brain of the prepubertal female rat
    • J.K. Hiney, V.K. Srivastava, M.D. Pine, and W. Les Dees Insulin-like growth factor-I activates KiSS-1 gene expression in the brain of the prepubertal female rat Endocrinology 150 1 2009 376 384
    • (2009) Endocrinology , vol.150 , Issue.1 , pp. 376-384
    • Hiney, J.K.1    Srivastava, V.K.2    Pine, M.D.3    Les Dees, W.4
  • 61
    • 0028113501 scopus 로고
    • Induction of vasoactive intestinal peptide gene expression and prolactin secretion by insulin-like growth factor i in rat pituitary cells: Evidence for an autoparacrine regulatory system
    • J.I. Lara, M.J. Lorenzo, and L. Cacicedo Induction of vasoactive intestinal peptide gene expression and prolactin secretion by insulin-like growth factor I in rat pituitary cells: evidence for an autoparacrine regulatory system Endocrinology 135 6 1994 2526 2532
    • (1994) Endocrinology , vol.135 , Issue.6 , pp. 2526-2532
    • Lara, J.I.1    Lorenzo, M.J.2    Cacicedo, L.3
  • 62
    • 0034913897 scopus 로고    scopus 로고
    • IGF-I as a mediator of VIP/activity-dependent neurotrophic factor-stimulated embryonic growth
    • S.J. Servoss, S.J. Lee, and G. Gibney IGF-I as a mediator of VIP/activity-dependent neurotrophic factor-stimulated embryonic growth Endocrinology 142 8 2001 3348 3353
    • (2001) Endocrinology , vol.142 , Issue.8 , pp. 3348-3353
    • Servoss, S.J.1    Lee, S.J.2    Gibney, G.3
  • 63
    • 0037232732 scopus 로고    scopus 로고
    • Nonhuman primate models of menopause workshop
    • F.L. Bellino, and P.M. Wise Nonhuman primate models of menopause workshop Biol Reprod 68 1 2003 10 18
    • (2003) Biol Reprod , vol.68 , Issue.1 , pp. 10-18
    • Bellino, F.L.1    Wise, P.M.2
  • 64
    • 33749070609 scopus 로고    scopus 로고
    • Neuroendocrine changes in the aging reproductive axis of female rhesus macaques (Macaca mulatta)
    • J.L. Downs, and H.F. Urbanski Neuroendocrine changes in the aging reproductive axis of female rhesus macaques (Macaca mulatta) Biol Reprod 75 4 2006 539 546
    • (2006) Biol Reprod , vol.75 , Issue.4 , pp. 539-546
    • Downs, J.L.1    Urbanski, H.F.2
  • 65
    • 0035178589 scopus 로고    scopus 로고
    • Estrogen and progesterone metabolites and follicle-stimulating hormone in the aged macaque female
    • S.E. Shideler, N.A. Gee, J. Chen, and B.L. Lasley Estrogen and progesterone metabolites and follicle-stimulating hormone in the aged macaque female Biol Reprod 65 6 2001 1718 1725
    • (2001) Biol Reprod , vol.65 , Issue.6 , pp. 1718-1725
    • Shideler, S.E.1    Gee, N.A.2    Chen, J.3    Lasley, B.L.4
  • 66
    • 4644344715 scopus 로고    scopus 로고
    • Menopausal increases in pulsatile gonadotropin-releasing hormone release in a nonhuman primate (Macaca mulatta)
    • A.C. Gore, B.M. Windsor-Engnell, and E. Terasawa Menopausal increases in pulsatile gonadotropin-releasing hormone release in a nonhuman primate (Macaca mulatta) Endocrinology 145 10 2004 4653 4659
    • (2004) Endocrinology , vol.145 , Issue.10 , pp. 4653-4659
    • Gore, A.C.1    Windsor-Engnell, B.M.2    Terasawa, E.3
  • 67
    • 0036096642 scopus 로고    scopus 로고
    • Negative feedback effects of gonadal steroids are preserved with aging in postmenopausal women
    • S. Gill, H.B. Lavoie, Y. Bo-Abbas, and J.E. Hall Negative feedback effects of gonadal steroids are preserved with aging in postmenopausal women J Clin Endocrinol Metab 87 5 2002 2297 2302
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.5 , pp. 2297-2302
    • Gill, S.1    Lavoie, H.B.2    Bo-Abbas, Y.3    Hall, J.E.4
  • 69
    • 0036656169 scopus 로고    scopus 로고
    • Age-related changes in the regulation of luteinizing hormone secretion by estrogen in women
    • S.J. Park, L.T. Goldsmith, and G. Weiss Age-related changes in the regulation of luteinizing hormone secretion by estrogen in women Exp Biol Med (Maywood) 227 7 2002 455 464
    • (2002) Exp Biol Med (Maywood) , vol.227 , Issue.7 , pp. 455-464
    • Park, S.J.1    Goldsmith, L.T.2    Weiss, G.3
  • 70
    • 0025277723 scopus 로고
    • Postmenopausal hypertrophy of neurons expressing the estrogen receptor gene in the human hypothalamus
    • N.E. Rance, N.T. McMullen, J.E. Smialek, D.L. Price, and W.S. Young 3rd. Postmenopausal hypertrophy of neurons expressing the estrogen receptor gene in the human hypothalamus J Clin Endocrinol Metab 71 1 1990 79 85
    • (1990) J Clin Endocrinol Metab , vol.71 , Issue.1 , pp. 79-85
    • Rance, N.E.1    McMullen, N.T.2    Smialek, J.E.3    Price, D.L.4    Young III, W.S.5
  • 71
    • 34447115135 scopus 로고    scopus 로고
    • Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys
    • A.M. Rometo, S.J. Krajewski, M.L. Voytko, and N.E. Rance Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys J Clin Endocrinol Metab 92 7 2007 2744 2750
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.7 , pp. 2744-2750
    • Rometo, A.M.1    Krajewski, S.J.2    Voytko, M.L.3    Rance, N.E.4
  • 72
    • 0034766548 scopus 로고    scopus 로고
    • Executive summary: Stages of Reproductive Aging Workshop (STRAW)
    • M.R. Soules, S. Sherman, and E. Parrott Executive summary: Stages of Reproductive Aging Workshop (STRAW) Fertil Steril 76 5 2001 874 878
    • (2001) Fertil Steril , vol.76 , Issue.5 , pp. 874-878
    • Soules, M.R.1    Sherman, S.2    Parrott, E.3
  • 73
    • 64049118403 scopus 로고    scopus 로고
    • Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition
    • G.E. Hale, C.L. Hughes, H.G. Burger, D.M. Robertson, and I.S. Fraser Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition Menopause 16 1 2009 50 59
    • (2009) Menopause , vol.16 , Issue.1 , pp. 50-59
    • Hale, G.E.1    Hughes, C.L.2    Burger, H.G.3    Robertson, D.M.4    Fraser, I.S.5
  • 75
    • 0036095455 scopus 로고    scopus 로고
    • Evidence that GnRH decreases with gonadal steroid feedback but increases with age in postmenopausal women
    • S. Gill, J.L. Sharpless, K. Rado, and J.E. Hall Evidence that GnRH decreases with gonadal steroid feedback but increases with age in postmenopausal women J Clin Endocrinol Metab 87 5 2002 2290 2296
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.5 , pp. 2290-2296
    • Gill, S.1    Sharpless, J.L.2    Rado, K.3    Hall, J.E.4
  • 76
    • 0034455736 scopus 로고    scopus 로고
    • Decrease in gonadotropin-releasing hormone (GnRH) pulse frequency with aging in postmenopausal women
    • J.E. Hall, H.B. Lavoie, E.E. Marsh, and K.A. Martin Decrease in gonadotropin-releasing hormone (GnRH) pulse frequency with aging in postmenopausal women J Clin Endocrinol Metab 85 5 2000 1794 1800
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.5 , pp. 1794-1800
    • Hall, J.E.1    Lavoie, H.B.2    Marsh, E.E.3    Martin, K.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.