Aquaporin-4 knockout enhances astrocyte toxicity induced by 1-methyl-4-phenylpyridinium ion and lipopolysaccharide via increasing the expression of cytochrome P4502E1

Toxicology Letters

Volumn 198, Issue 2, 2010, Pages 225-231

  Hao, Chunshu ^a   Liu, Wei ^a   Luan, Xiaofei ^a   Li, Yang ^a   Gui, Haiyan ^a   Peng, Yan ^a   Shen, Jianping ^a   Hu, Gang ^a   Yang, Jian ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Aquaporin 4; Astrocytes; Cytochrome P4502E1; MPP+; ROS

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ALCOHOL; ALLYL SULFIDE; AQUAPORIN 4; CYTOCHROME P450 2E1; LIPOPOLYSACCHARIDE; REACTIVE OXYGEN METABOLITE;

ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOTOXICITY; GENE INACTIVATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; AQUAPORIN 4; ASTROCYTES; BRAIN; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROME P-450 CYP2E1; ETHANOL; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 77955918579     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.06.023     Document Type: Article

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