New generation of chitosan-encapsulated ZnO quantum dots loaded with drug: Synthesis, characterization and in vitro drug delivery response

Acta Biomaterialia

Volumn 6, Issue 7, 2010, Pages 2732-2739

  Yuan, Q ^a   Hein, S ^b   Misra, R D K ^a  

^a UNIVERSITY OF LOUISIANA AT LAFAYETTE   (United States)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Chitosan; Controlled drug release; Nanocarrier; Quantum dots

Indexed keywords

BIOCOMPATIBILITY; CHEMICAL STABILITY; CHITOSAN; CONTROLLED DRUG DELIVERY; DISEASES; DRUG PRODUCTS; FLUORESCENCE; II-VI SEMICONDUCTORS; NANOCRYSTALS; TARGETED DRUG DELIVERY; TUMORS; ZINC OXIDE;

ANTICANCER DRUG; BLUE LIGHT-EMITTING; CONTROLLED DRUG RELEASE; DRUG SYNTHESIS; IN-VITRO; N-ACETYLGLUCOSAMINE; NANOCARRIERS; NEW APPROACHES; WATER-DISPERSED; ZNO QUANTUM DOTS;

SEMICONDUCTOR QUANTUM DOTS;

CHITOSAN; DOXORUBICIN; FOLIC ACID; NANOCARRIER; QUANTUM DOT; ZINC OXIDE;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG STABILITY; DRUG SYNTHESIS; ENCAPSULATION; HYDROLYSIS; HYDROPHILICITY; IN VITRO STUDY; PRIORITY JOURNAL; CHEMISTRY; INFRARED SPECTROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

CHITOSAN; DRUG DELIVERY SYSTEMS; MICROSCOPY, ELECTRON, TRANSMISSION; QUANTUM DOTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; ZINC OXIDE;

EID: 77955912178     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.01.025     Document Type: Article

References (38)

1. Moghimi SM, Rajabi-Siahboomi AR. Recent advances in cellular, sub-cellular and molecular targeting. Adv Drug Deliv Rev 2000;41:129-33.
2. Jaracz S, Chen J, Kuznetsova LV, Olima I. Recent advances in tumor-targeting anticancer drug conjugates. Bioorg Med Chem 2005;13:5043-54.
3. Weitman SD, Lark RH, Coney LR, Fort DW, Frasca V, Zurawski VR, et al. Distribution of the folate receptor GP38 in normal and malignant-cell lines and tissues. Cancer Res 1992;52:3396-401.
4. Antony AC. Folate receptors. Annu Rev Nutr 1996;16:501-21.
5. Lu Y, Low PS. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev 2002;54:675-93.
6. Maziarz KM, Monaco HL, Shen F, Ratnam M. Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors alpha and beta. J Biol Chem 1999;274:11086-91.
7. Mansouri S, Cuie Y, Winnik F, Shi Q, Lavigne P, Benderdour M, et al. Characterization of folate-chitosan-DNA nanoparticles for gene therapy. Biomaterials 2006;27:2060-5.
8. Kim TH, Park IK, Nah JW, Choi YJ, Cho CS. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. Biomaterials 2004;25:3783-92.
9. Hood JD, Bednarksi M, Frausto R, Guccione S, Reisfeld RA, Xiang R. Tumor recognition by targeted gene delivery to the neovasculature. Science 2002;296:2404-7.
10. Zhang JL, Srivastava RS, Misra RDK. Core-shell magnetite nanoparticles surface encapsulated with smart stimuli-responsive polymer: synthesis, characterization and LCST of viable drug-targeting delivery system. Langmuir 2007;23:6342-51.
11. Zhang JL, Misra RDK. Magnetic drug targeting carrier encapsulated with thermosensitive smart polymer core-shell nanoparticle carrier and drug release response. Acta Biomater. 2007;3:838-50.
12. Yuan Q, Venkatasubramanian R, Hein S, Misra RDK. Stimuli-responsive magnetic nanoparticle drug carrier: magnetite encapsulated with chitosangrafted-copolymer. Acta Biomater 2008;4:1024-37.
13. Jaiswai JK, Mattoussi H, Mauro JM, Simon SM. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat Biotechnol 2003;21:47-51.
14. Gao X, Cui Y, Levenson RM, Chung LW, Nie S. In-vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 2004;22:969-76.
15. Jamieson T, Bakshi R, Petrova D, Pocock R, Imani M, Seifalian AM. Biological applications of quantum dots. Biomaterials 2007;28:4717-32.
16. Eychmuller A, Rogach AL. Spectroscopic and their physical properties - chemistry and photophysics of thiol-stabilized II-VI semiconductor nanocrystals. Pure Appl Chem 2000;72:179-88.
17. Gerion D, Pinaud F, Williams SC, Parak WJ, Zanchet D, Weiss S, et al. Synthesis and properties of biocompatible water-soluble silica-coated CdSe/ZnS semiconductor quantum dots. J Phys Chem B 2001;105:8861-71.
18. Mitchell GP, Mirkin CA, Letsinger RL. Programmed assembly of DNA functionalized QDs. J Am Chem Soc 1999;121:8122-3.
19. Weng KC, Noble CO, P-Sternberg B, Chen FF, Drummond DC, Kirpotin DB, et al. Targeted tumor cell internalization and imaging of multifunctional quantum dot conjugated immunoliposomes in vitro and in vivo. Nano Lett 2008;8:2851-7.
20. Dutta PK, Ravikumar MN, Dutta J. Chitin and chitosan for versatile applications. J Macromol Sci C Polym Rev 2002; C42:307-54.
21. Hirano S. Chitin biotechnology applications. Biotechnol Ann Rev 1996;2:237-58.
22. Gupta KC, Jabrail FH. Effects of deacetylation and cross-linking on physical characteristics, swelling and release behavior of chitosan microspheres. Carbohydr Polym 2006;66:43-54.
23. Ng CH, Hein S, Chandrkrachang S, Stevens WF. Evaluation of an improved acid hydrolysis-HPLC assay for the acetyl content in chitin and chitosan. J Biomed Mater Res B 2006;76 B: 155-60.
24. Huang HZ, Yang XR. Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method. Carbohydr Res 2004;339:2627-31.
25. Feng JJ, Zhao G, Xu JJ, Chen HY. Direct electrochemistry and electrocatalysis of heme proteins immobilized on gold nanoparticles stabilized by chitosan. Anal Biochem 2005;342:280-6. (Pubitemid 40884577)
26. Huang HZ, Yuan Q, Yang XR. Morphology study of gold-chitosan nanocomposites. J Colloid Interface Sci 2005;282:26-31.
27. Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosanbased micro-and nanoparticles in drug delivery. J Control Release 2004;100:5-28.
28. Janes KA, Fresneau MP, Marazuela A, Fabra A, Alonso MJ. Chitosan nanoparticles as delivery systems for doxorubicin. J Control Release 2001;73:255-67.
29. Derfus AM, Chan WCW, Bhatia SN. Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 2004;4:11-8.
30. Fischer Ch-H, Lilie J, Weller H, Katsikas L, Henglein A. Photochemistry of colloidal semiconductors. 29. Fractionation of CdS sols of small particles by exclusion chromatograph. Phys Chem Chem Phys 1989;93:61-4.
31. Liu M, Kitai AH, Mascher P. Point defects and luminescence centres in zinc oxide and zinc oxide doped with manganese. J Lumin 1992;54:35-42.
32. Susumu T, Emi A, Kohei H, Shinichi O, Yuzuru K. Zinc ions suppress mitogenactivated interleukin-2 production in Jurkat cells. Biochem Biophys Res Commun 2005;335:162-7.
33. Sutherland LC, Anderson CL, Williams GT. Zinc has no effect on IL-3-mediated apoptosis of BAF-3 cells but enhances CD95-mediated apoptosis of Jurkat cells. J Immunol Methods 2000;234:43-50.
34. Fu YS, Du XW, Kulinich SA, Qiu JS, Qin WJ, Li R, et al. Stable aqueous dispersion of ZnO quantum dots with strong blue emission via simple solution route. J Am Chem Soc 2007;129:16029-33.
35. Wu YL, Lim CS, Fu S, Tok AIY, Lau HM, Boey FYC, et al. Surface modifications of ZnO quantum dots for bio-imaging. Nanotechnology 2007;18:215604 (9pp).
36. Rodriguez-Gattorno G, Santiago-Jacinto P, Rendon-Vazquez L, Nemeth J, Dekany I, Diaz D. Novel synthesis pathway of ZnO nanoparticles from the spontaneous hydrolysis of zinc carboxylate salts. J Phys Chem B 2003;107:12597-604.
37. Zhang JL, Rana S, Srivastava RS, Misra RDK. On the chemical synthesis and drug delivery response of folate-receptor-activated, polyethylene glycolfunctionalized magnetite nanoparticles. Acta Biomater 2008;4:40.
38. Xiong HM, Xu Y, Ren QG, Xia YY. Stable aqueous ZnO-polymer core-shell nanoparticles with tunable photoluminescence and their application in cell imaging. J Am Chem Soc 2008;130:7522-3.