Mitochondrial DNA defects and selective extraocular muscle involvement in CPEO

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 7, 2010, Pages 3340-3346

  Greaves, Laura C ^a   Yu Wai Man, Patrick ^a,b   Blakely, Emma L ^a   Krishnan, Kim J ^a   Beadle, Nina E ^a   Kerin, Jamie ^a   Barron, Martin J ^a   Griffiths, Philip G ^a,b   Dickinson, Alison J ^b   Turnbull, Douglass M ^a   Taylor, Robert W ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; SUCCINATE DEHYDROGENASE;

ADOLESCENT; ADULT; ARTICLE; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOCHROME C OXIDASE DEFICIENCY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME ACTIVITY; EXTRAOCULAR MUSCLE; GENE EXPRESSION; GENE MUTATION; GENETIC DISORDER; HISTOCHEMISTRY; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR GENETICS; MUSCLE CELL; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TISSUE SECTION; TISSUE SPECIFICITY; ENZYMOLOGY; GENE DOSAGE; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; MUSCLE MITOCHONDRION; NUCLEOTIDE SEQUENCE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE;

ADOLESCENT; ADULT; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; GENE DOSAGE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL DISEASES; MUSCLE FIBERS, SKELETAL; OCULOMOTOR MUSCLES; OPHTHALMOPLEGIA, CHRONIC PROGRESSIVE EXTERNAL; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; QUADRICEPS MUSCLE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUCCINATE DEHYDROGENASE; YOUNG ADULT;

EID: 77955888547     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4659     Document Type: Article

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