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Volumn 3, Issue 4, 2010, Pages 416-429

Molecular classification of soft tissue sarcomas and its clinical applications

Author keywords

molecular classification; Molecular genetics; Sarcomas; Soft tissue tumors; Specific genetic translocation

Indexed keywords

CLASSIFICATION; GENETICS; HUMAN; REVIEW; SARCOMA; SOFT TISSUE TUMOR;

EID: 77955880551     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (107)

References (45)
  • 1
    • 34548446433 scopus 로고    scopus 로고
    • Sarcomas: Genetics, signalling, and cellular origins. Part 1: The fellowship of TET
    • Riggi N, Cironi L, Suva ML and Stamenkovic I. Sarcomas: Genetics, signalling, and cellular origins. Part 1: The fellowship of TET. J Pathol 2007; 213: 4-20.
    • (2007) J Pathol , vol.213 , pp. 4-20
    • Riggi, N.1    Cironi, L.2    Suva, M.L.3    Stamenkovic, I.4
  • 2
    • 33646146940 scopus 로고    scopus 로고
    • Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma
    • Olsen SH, Thomas DG and Lucas DR. Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma. Mod Pathol 2006; 19: 659-668.
    • (2006) Mod Pathol , vol.19 , pp. 659-668
    • Olsen, S.H.1    Thomas, D.G.2    Lucas, D.R.3
  • 3
    • 0033989280 scopus 로고    scopus 로고
    • Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family
    • de Alava E and Gerald WL. Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family. J Clin Oncol 2000; 18: 204-213.
    • (2000) J Clin Oncol , vol.18 , pp. 204-213
    • de Alava, E.1    Gerald, W.L.2
  • 4
    • 33646893256 scopus 로고    scopus 로고
    • The usefulness of cytogenetic analysis in fine needle aspirates for the histologic subtyping of sarcomas
    • Kilpatrick SE, Bergman S, Pettenati MJ and Gulley ML. The usefulness of cytogenetic analysis in fine needle aspirates for the histologic subtyping of sarcomas. Mod Pathol 2006; 19: 815-819.
    • (2006) Mod Pathol , vol.19 , pp. 815-819
    • Kilpatrick, S.E.1    Bergman, S.2    Pettenati, M.J.3    Gulley, M.L.4
  • 5
    • 0033119006 scopus 로고    scopus 로고
    • Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma
    • Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH and Ladanyi M. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res 1999; 59: 1428-1432.
    • (1999) Cancer Res , vol.59 , pp. 1428-1432
    • Lin, P.P.1    Brody, R.I.2    Hamelin, A.C.3    Bradner, J.E.4    Healey, J.H.5    Ladanyi, M.6
  • 7
    • 33846949677 scopus 로고    scopus 로고
    • Small round cell tumors of bone
    • Hameed M. Small round cell tumors of bone. Arch Pathol Lab Med 2007; 131: 192-204.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 192-204
    • Hameed, M.1
  • 8
    • 0028246185 scopus 로고
    • Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor
    • Ladanyi M and Gerald W. Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor. Cancer Res 1994; 54: 2837-2840.
    • (1994) Cancer Res , vol.54 , pp. 2837-2840
    • Ladanyi, M.1    Gerald, W.2
  • 9
    • 55949121548 scopus 로고    scopus 로고
    • A new molecular variant of desmoplastic small round cell tumor: significance of WT1 immunostaining in this entity
    • Murphy AJ, Bishop K, Pereira C, Chilton-MacNeill S, Ho M, Zielenska M and Thorner PS. A new molecular variant of desmoplastic small round cell tumor: significance of WT1 immunostaining in this entity. Hum Pathol 2008; 39: 1763-1770.
    • (2008) Hum Pathol , vol.39 , pp. 1763-1770
    • Murphy, A.J.1    Bishop, K.2    Pereira, C.3    Chilton-MacNeill, S.4    Ho, M.5    Zielenska, M.6    Thorner, P.S.7
  • 12
    • 0029116341 scopus 로고
    • Translocation t (9;22)(q22;q12) is a primary cytogenetic abnormality in extraskeletal myxoid chondrosarcoma
    • Stenman G, Andersson H, Mandahl N, Meis-Kindblom JM and Kindblom LG. Translocation t (9;22)(q22;q12) is a primary cytogenetic abnormality in extraskeletal myxoid chondrosarcoma. Int J Cancer 1995; 62: 398-402.
    • (1995) Int J Cancer , vol.62 , pp. 398-402
    • Stenman, G.1    Andersson, H.2    Mandahl, N.3    Meis-Kindblom, J.M.4    Kindblom, L.G.5
  • 13
    • 0030033829 scopus 로고    scopus 로고
    • Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma
    • Clark J, Benjamin H, Gill S, Sidhar S, Goodwin G, Crew J, Gusterson BA, Shipley J and Cooper CS. Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma. Oncogene 1996; 12: 229-235.
    • (1996) Oncogene , vol.12 , pp. 229-235
    • Clark, J.1    Benjamin, H.2    Gill, S.3    Sidhar, S.4    Goodwin, G.5    Crew, J.6    Gusterson, B.A.7    Shipley, J.8    Cooper, C.S.9
  • 14
    • 0345074093 scopus 로고    scopus 로고
    • Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcomacytogenetic, molecular genetic, and cDNA microarray analyses
    • Sjogren H, Meis-Kindblom JM, Orndal C, Bergh P, Ptaszynski K, Aman P, Kindblom LG and Stenman G. Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcomacytogenetic, molecular genetic, and cDNA microarray analyses. Am J Pathol 2003; 162: 781-792.
    • (2003) Am J Pathol , vol.162 , pp. 781-792
    • Sjogren, H.1    Meis-Kindblom, J.M.2    Orndal, C.3    Bergh, P.4    Ptaszynski, K.5    Aman, P.6    Kindblom, L.G.7    Stenman, G.8
  • 15
    • 3142654700 scopus 로고    scopus 로고
    • TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcoma
    • Hisaoka M, Ishida T, Imamura T and Hashimoto H. TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcoma. Genes Chromosomes Cancer 2004; 40: 325-328.
    • (2004) Genes Chromosomes Cancer , vol.40 , pp. 325-328
    • Hisaoka, M.1    Ishida, T.2    Imamura, T.3    Hashimoto, H.4
  • 16
    • 0032531726 scopus 로고    scopus 로고
    • Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study
    • Antonescu CR, Argani P, Erlandson RA, Healey JH, Ladanyi M and Huvos AG. Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study. Cancer 1998; 83: 1504-1521.
    • (1998) Cancer , vol.83 , pp. 1504-1521
    • Antonescu, C.R.1    Argani, P.2    Erlandson, R.A.3    Healey, J.H.4    Ladanyi, M.5    Huvos, A.G.6
  • 17
    • 57649115642 scopus 로고    scopus 로고
    • DNA-based polymerase chain reaction for detecting FUS-CREB3L2 in low-grade fibromyxoid sarcoma using formalin-fixed, paraffinembedded tissue specimens
    • Matsuyama A, Hisaoka M, Shimajiri S and Hashimoto H. DNA-based polymerase chain reaction for detecting FUS-CREB3L2 in low-grade fibromyxoid sarcoma using formalin-fixed, paraffinembedded tissue specimens. Diagn Mol Pathol 2008; 17: 237-240.
    • (2008) Diagn Mol Pathol , vol.17 , pp. 237-240
    • Matsuyama, A.1    Hisaoka, M.2    Shimajiri, S.3    Hashimoto, H.4
  • 18
    • 0031738824 scopus 로고    scopus 로고
    • Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma
    • Rubin BP, Chen CJ, Morgan TW, Xiao S, Grier HE, Kozakewich HP, Perez-Atayde AR and Fletcher JA. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol 1998; 153: 1451-1458.
    • (1998) Am J Pathol , vol.153 , pp. 1451-1458
    • Rubin, B.P.1    Chen, C.J.2    Morgan, T.W.3    Xiao, S.4    Grier, H.E.5    Kozakewich, H.P.6    Perez-Atayde, A.R.7    Fletcher, J.A.8
  • 21
    • 0033966745 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma
    • Oda Y, Sakamoto A, Saito T, Kinukawa N, Iwamoto Y and Tsuneyoshi M. Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma. Hum Pathol 2000; 31: 185-192.
    • (2000) Hum Pathol , vol.31 , pp. 185-192
    • Oda, Y.1    Sakamoto, A.2    Saito, T.3    Kinukawa, N.4    Iwamoto, Y.5    Tsuneyoshi, M.6
  • 22
    • 34247599745 scopus 로고    scopus 로고
    • Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimens
    • Kanemitsu S, Hisaoka M, Shimajiri S, Matsuyama A and Hashimoto H. Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimens. Diagn Mol Pathol 2007; 16: 9-17.
    • (2007) Diagn Mol Pathol , vol.16 , pp. 9-17
    • Kanemitsu, S.1    Hisaoka, M.2    Shimajiri, S.3    Matsuyama, A.4    Hashimoto, H.5
  • 25
    • 0036654370 scopus 로고    scopus 로고
    • Establishment of a new human synovial sarcoma cell line, FU-SY-1, that expresses c-Met receptor and its ligand hepatocyte growth factor
    • Nishio J, Iwasaki H, Ishiguro M, Ohjimi Y, Fujita C, Isayama T, Naito M, Oda Y, Kaneko Y and Kikuchi M. Establishment of a new human synovial sarcoma cell line, FU-SY-1, that expresses c-Met receptor and its ligand hepatocyte growth factor. Int J Oncol 2002; 21: 17-23.
    • (2002) Int J Oncol , vol.21 , pp. 17-23
    • Nishio, J.1    Iwasaki, H.2    Ishiguro, M.3    Ohjimi, Y.4    Fujita, C.5    Isayama, T.6    Naito, M.7    Oda, Y.8    Kaneko, Y.9    Kikuchi, M.10
  • 27
    • 0034879412 scopus 로고    scopus 로고
    • Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection
    • Nishio J, Iwasaki H, Ishiguro M, Ohjimi Y, Isayama T, Naito M and Kikuchi M. Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection. Virchows Arch 2001; 439: 152-157.
    • (2001) Virchows Arch , vol.439 , pp. 152-157
    • Nishio, J.1    Iwasaki, H.2    Ishiguro, M.3    Ohjimi, Y.4    Isayama, T.5    Naito, M.6    Kikuchi, M.7
  • 29
    • 0037229726 scopus 로고    scopus 로고
    • Real-time polymerase chain reaction as an aid for the detection of SYT-SSX1 and SYT-SSX2 transcripts in fresh and archival pediatric synovial sarcoma specimens: report of 25 cases from St Jude Children's Research Hospital
    • Hill DA, Riedley SE, Patel AR, Shurtleff SA, Hyer J, Cain AM, Billups CA, Downing JR and Pappo AS. Real-time polymerase chain reaction as an aid for the detection of SYT-SSX1 and SYT-SSX2 transcripts in fresh and archival pediatric synovial sarcoma specimens: report of 25 cases from St. Jude Children's Research Hospital. Pediatr Dev Pathol 2003; 6: 24-34.
    • (2003) Pediatr Dev Pathol , vol.6 , pp. 24-34
    • Hill, D.A.1    Riedley, S.E.2    Patel, A.R.3    Shurtleff, S.A.4    Hyer, J.5    Cain, A.M.6    Billups, C.A.7    Downing, J.R.8    Pappo, A.S.9
  • 30
    • 73349127025 scopus 로고    scopus 로고
    • Prospective Evaluation of TLE1 as a Diagnostic Immunohistochemical Marker in Synovial Sarcoma
    • Jagdis A, Rubin BP, Tubbs RR, Pacheco M and Nielsen TO. Prospective Evaluation of TLE1 as a Diagnostic Immunohistochemical Marker in Synovial Sarcoma. Am J Surg Pathol 2009; 33 (12):1743-51.
    • (2009) Am J Surg Pathol , vol.33 , Issue.12 , pp. 1743-1751
    • Jagdis, A.1    Rubin, B.P.2    Tubbs, R.R.3    Pacheco, M.4    Nielsen, T.O.5
  • 32
    • 33748068096 scopus 로고    scopus 로고
    • Dermatofibrosarcoma protuberans: a surgical disease with a molecular savior
    • McArthur GA. Dermatofibrosarcoma protuberans: a surgical disease with a molecular savior. Curr Opin Oncol 2006; 18: 341-346.
    • (2006) Curr Opin Oncol , vol.18 , pp. 341-346
    • McArthur, G.A.1
  • 34
    • 33746895755 scopus 로고    scopus 로고
    • Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas
    • Davicioni E, Finckenstein FG, Shahbazian V, Buckley JD, Triche TJ and Anderson MJ. Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas. Cancer Res 2006; 66: 6936-6946.
    • (2006) Cancer Res , vol.66 , pp. 6936-6946
    • Davicioni, E.1    Finckenstein, F.G.2    Shahbazian, V.3    Buckley, J.D.4    Triche, T.J.5    Anderson, M.J.6
  • 35
    • 41749110288 scopus 로고    scopus 로고
    • Detection of FOXO1 (FKHR) gene break-apart by fluorescence in situ hybridization in formalin-fixed, paraffinembedded alveolar rhabdomyosarcomas and its clinicopathologic correlation
    • Mehra S, de la Roza G, Tull J, Shrimpton A, Valente A and Zhang S. Detection of FOXO1 (FKHR) gene break-apart by fluorescence in situ hybridization in formalin-fixed, paraffinembedded alveolar rhabdomyosarcomas and its clinicopathologic correlation. Diagn Mol Pathol 2008; 17: 14-20.
    • (2008) Diagn Mol Pathol , vol.17 , pp. 14-20
    • Mehra, S.1    de la Roza, G.2    Tull, J.3    Shrimpton, A.4    Valente, A.5    Zhang, S.6
  • 37
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis
    • Miettinen M and Lasota J. Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med 2006; 130: 1466-1478.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 39
    • 68349137634 scopus 로고    scopus 로고
    • Re: Infrequent SMARCB1/INI1 gene alteration in epithelioid sarcoma: a useful tool in distinguishing epithelioid sarcoma from malignant rhabdoid tumor: Direct evidence of mutational inactivation of SMARCB1/INI1 in epithelioid sarcoma
    • author reply 1362-1364
    • Flucke U, Slootweg PJ, Mentzel T, Pauwels P and Hulsebos TJ. Re: Infrequent SMARCB1/INI1 gene alteration in epithelioid sarcoma: a useful tool in distinguishing epithelioid sarcoma from malignant rhabdoid tumor: Direct evidence of mutational inactivation of SMARCB1/INI1 in epithelioid sarcoma. Hum Pathol 2009; 40: 1361-1362; author reply 1362-1364.
    • (2009) Hum Pathol , vol.40 , pp. 1361-1362
    • Flucke, U.1    Slootweg, P.J.2    Mentzel, T.3    Pauwels, P.4    Hulsebos, T.J.5
  • 42
    • 34547102253 scopus 로고    scopus 로고
    • Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma
    • Singer S, Socci ND, Ambrosini G, Sambol E, Decarolis P, Wu Y, O'Connor R, Maki R, Viale A, Sander C, Schwartz GK and Antonescu CR. Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer Res 2007; 67: 6626-6636.
    • (2007) Cancer Res , vol.67 , pp. 6626-6636
    • Singer, S.1    Socci, N.D.2    Ambrosini, G.3    Sambol, E.4    Decarolis, P.5    Wu, Y.6    O'Connor, R.7    Maki, R.8    Viale, A.9    Sander, C.10    Schwartz, G.K.11    Antonescu, C.R.12
  • 43
    • 34447293996 scopus 로고    scopus 로고
    • The role of mTOR inhibitors for treatment of sarcomas
    • Mita MM and Tolcher AW. The role of mTOR inhibitors for treatment of sarcomas. Curr Oncol Rep 2007; 9: 316-322.
    • (2007) Curr Oncol Rep , vol.9 , pp. 316-322
    • Mita, M.M.1    Tolcher, A.W.2
  • 44
    • 8444226791 scopus 로고    scopus 로고
    • Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study
    • Bridge RS, Jr., Bridge JA, Neff JR, Naumann S, Althof P and Bruch LA. Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study. J Clin Pathol 2004; 57: 1172-1178.
    • (2004) J Clin Pathol , vol.57 , pp. 1172-1178
    • Bridge R.S., Jr.1    Bridge, J.A.2    Neff, J.R.3    Naumann, S.4    Althof, P.5    Bruch, L.A.6
  • 45
    • 32544437208 scopus 로고    scopus 로고
    • Iwasaki H. cDNA microarray analysis of cancer associated gene expression profiles in malignant peripheral nerve sheath tumours
    • Karube K, Nabeshima K, Ishiguro M, Harada M and Iwasaki H. cDNA microarray analysis of cancer associated gene expression profiles in malignant peripheral nerve sheath tumours. J Clin Pathol 2006; 59: 160-165.
    • (2006) J Clin Pathol , vol.59 , pp. 160-165
    • Karube, K.1    Nabeshima, K.2    Ishiguro, M.3    Harada, M.4


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