Cerebrovascular dynamics in response to neural stimulation

Hirosaki Medical Journal

Volumn 61, Issue SUPPL., 2010, Pages

  Masamoto, Kazuto ^a,b   Obata, Takayuki ^b   Kanno, Iwao ^b  

^a UNIVERSITY OF ELECTRO COMMUNICATIONS   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Functional brain mapping; In vivo optical imaging; Neurovascular coupling; Two photon microscopy

Indexed keywords

EID: 77955869770     PISSN: 04391721     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. LaManna JC, Vendel LM, Farrell RM. Brain adaptation to chronic hypobaric hypoxia in rats. J Appl Physiol 1992;72:223843.
2. Mironov V, Hritz MA, LaManna JC, Hudetz AG, Harik SI. Architectural alterations in rat cerebral microvessels after hypobaric hypoxia. Brain Res 1994;660:73-80.
3. Boero JA, Ascher J, Arregui A, Rovainen C, Woolsey TA. Increased brain capillaries in chronic hypoxia. J Appl Physiol 1999;86:1211-9.
4. Hudetz AG. Mathematical model of oxygen transport in the cerebral cortex. Brain Res 1999; 817:75-83.
5. Rosenblum WI. Cerebral microcirculation: A review emphasizing the interrelationship of local blood flow and neuronal function. Angiology 1965; 16:485-507.
6. Villringer A, Dirnagl U. Coupling of brain activity and cerebral blood flow: basis of functional neu-roimaging. Cerebrovasc Brain Metab Rev 1995; 7:240-76.
7. Lauritzen M. Relationship of spikes, synaptic activity, and local changes of cerebral blood flow. J Cereb Blood Flow Metab 2001;21:1367-83.
8. Iadecola C. Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci 2004;5:347-60.
9. Straub SV, Nelson MT. Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation. Trends Cardiovasc Med 2007;17:183-90.
10. Segal SS, Duling BR. Flow control among microvessels coordinated by intercellular conduction. Science 1986;234:868-70.
11. Segal SS. Regulation of blood flow in the microcirculation. Microcirculation 2005;12:3345.
12. Horiuchi T, Dietrich HH, Hongo K, Dacey RG Jr. Mechanism of extracellular K+-induced local and conducted responses in cerebral penetrating arterioles. Stroke 2002;33:2692-9.
13. Iadecola C, Yang G, Ebner TJ, Chen G. Local and propagated vascular responses evoked by focal synaptic activity in cerebellar cortex. J Neuro-physiol 1997;78:651-9.
14. Xu HL, Mao L, Ye S, Paisansathan C, Vetri F, Pelligrino DA. Astrocytes are a key conduit for upstream signaling of vasodilation during cerebral cortical neuronal activation in vivo. Am J Physiol Heart Circ Physiol 2008;294:H622-32.
15. Masamoto K, Kim T, Fukuda M, Wang P, Kim SG. Relationship between neural, vascular, and BOLD signals in isoflurane-anesthetized rat somatosensory cortex. Cereb Cortex 2007;17:942-50.
16. Ngai AC, Meno JR, Winn HR. Simultaneous measurements of pial arteriolar diameter and laser-Doppler flow during somatosensory stimulation. J Cereb Blood Flow Metab 1995;15:124-7.
17. Moskalenko YE, Woolsey TA, Rovainen C, et al. Blood flow dynamics in different layers of the somatosensory region of the cerebral cortex on the rat during mechanical stimulation of the vibrissae. Neurosci Behav Physiol 1998;28:459-67.
18. Gerrits RJ, Raczynski C, Greene AS, Stein EA. Regional cerebral blood flow responses to variable frequency whisker stimulation: an autoradiographic analysis. Brain Res 2000;864:205-12.
19. Silva AC, Koretsky AP. Laminar specificity of functional MRI onset times during somatosensory. stimulation in rat Proc Natl Acad Sci U S A 2002; 99:15182-7.
20. Zhao F, Wang P, Hendrich K, Ugurbil K, Kim SG. Cortical layer-dependent BOLD and CBV responses measured by spin-echo and gradient-echo fMRI: insights into hemodynamic regulation. Neuroimage 2006;30:1149-60.
21. Jin T, Kim SG. Cortical layer-dependent dynamic blood oxygenation, cerebral blood flow and cerebral blood volume responses during visual stimulation. Neuroimage 2008;43:1-9.
22. Chen Y, Aguirre AD, Ruvinskaya L, Devor A, Boas DA, Fujimoto JG. Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation. J Neurosci Methods 2009;178:162-73.
23. Duling BR, Berne RM. Propagated vasodilation in the microcirculation of the hamster cheek pouch. Circ Res 1970;26:163-70.
24. 2+ waves and arteriolar dilation in vivo: measurements in Cx40BAC GCaMP2 transgenic mice. Circ Res 2007;101:1300-9.
25. Uhrenholt TR, Domeier TL, Segal SS. Propagation of calcium waves along endothelium of hamster feed arteries. Am J Physiol Heart Circ Physiol 2007;292:H163440.