Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro

Kidney International

Volumn 77, Issue 11, 2010, Pages 974-988

  Chen, Zhao Hong ^a   Qin, Wei Song ^a   Zeng, Cai Hong ^a   Zheng, Chun Xia ^a   Hong, Yi Mei ^a   Lu, Yi Zhou ^a   Li, Lei Shi ^a   Liu, Zhi Hong ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

complement system; passive Heymann nephritis; podocyte; proteinuria; triptolide

Indexed keywords

DESMIN; IMMUNOGLOBULIN G ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRIPTOLIDE; COMPLEMENT MEMBRANE ATTACK COMPLEX; DITERPENE; EPOXIDE; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; NEPHRITOGENIC ANTIGEN; PHENANTHRENE DERIVATIVE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, MOUSE; TACROLIMUS;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GASTROINTESTINAL DISEASE; HEYMANN NEPHRITIS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LEUKOPENIA; LIVER TOXICITY; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEINURIA; QUANTITATIVE ANALYSIS; RAT; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; BLOOD; CELL LINE; DISEASE MODEL; FEMALE; IMMUNOLOGY; MEMBRANOUS GLOMERULONEPHRITIS; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; PATHOLOGY; RABBIT; SPRAGUE DAWLEY RAT; TIME; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; CELL LINE; COMPLEMENT MEMBRANE ATTACK COMPLEX; CYTOPROTECTION; DESMIN; DISEASE MODELS, ANIMAL; DITERPENES; EPOXY COMPOUNDS; FEMALE; GLOMERULONEPHRITIS, MEMBRANOUS; HEYMANN NEPHRITIS ANTIGENIC COMPLEX; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENTS; MICE; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENANTHRENES; PODOCYTES; PROTEINURIA; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TACROLIMUS; TIME FACTORS;

EID: 77955865476     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.41     Document Type: Article

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