Fall in implantation rates following ICSI with sperm with high DNA fragmentation

Human Reproduction

Volumn 25, Issue 7, 2010, Pages 1609-1618

  Speyer, B E ^a   Pizzey, A R ^a   Ranieri, M ^b   Joshi, R ^b   Delhanty, J D A ^a   Serhal, P ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

DNA damage; implantation; IVF ICSI outcome; male infertility; midpiece defects

Indexed keywords

DNA FRAGMENT;

ADULT; ADVERSE OUTCOME; ARTICLE; CHROMATIN STRUCTURE; DNA FRAGMENTATION; FEMALE; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; MORULA; PREGNANCY OUTCOME; SEMEN ABNORMALITY; TREATMENT FAILURE;

EID: 77955855984     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq116     Document Type: Article

References (45)

1. Adams C, Anderson L, Wood S. High, but not moderate, levels of sperm DNA fragmentation are predictive of poor outcome in egg donation cycles. Fertil Steril 2004;82(Suppl. 2):S44.
2. Ahmadi A, Ng S. Fertilizing ability of DNA-damaged spermatozoa. J Exp Zool 1999;284:696-704.
3. Aitken RJ, De Iullis GN. Origins and consequencies of DNA damage in male germ cells. Reprod Biomed Online 2007;14:727-733.
4. Aitken RJ, De Iullis GN. On the possible origins of DNA damage in human spermatozoa. Mol Hum Reprod 2010;16:3-13.
5. Bakos HW, Thompson JG, Feil D, Lane M. Sperm DNA damage is associated with assisted reproductive technology pregnancy. Int J Androl 2007;31:518-526.
6. Ballachey BE, Hohenboken WD, Evenson DP. Heterogeneity of sperm nuclear chromatin structure and its relationship to bull fertility. Biol Reprod 1987;36:915-925.
7. Bartoov B, Berkovitz A, Eltes F, Kogosowski A, Menezo Y, Barak Y. Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome. J Androl 2002;23:1-8.
8. Benchaib M, Braun V, Lornage J, Hadj S, Salle B, Lejeune H, Guerin JF. Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique. Hum Reprod 2003;18:1023-1028.
9. Boe-Hansen GB, Fedder J, Ersboll AK, Christensen P. The sperm chromatin structure assay as a diagnostic tool in the human fertility clinic. Hum Reprod 2006;21:1576-1582.
10. Borini A, Tarozzi N, Bizzaro D, Bonu MA, Fava L, Flamigni C, Coticchio G. Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART. Hum Reprod 2006; 21:2876-2881.
11. Braude P, Bolton V, Moore S. Human gene expression first occurs between the four-and eight-cell stages of preimpantation development. Nature 1988;332:459-461.
12. Bungum M, Humaidan P, Spano M, Jepson K, Bungum L, Giwercman A. The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod 2004;19:1401-1408.
13. Bungum M, Humaidan P, Axmon A, Spano M, Bungum L, Erenpreiss J, Giwercman A. Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome. Hum Reprod 2007; 22:174-179.
14. Caglar GS, Koster F, Schopper B, Asimakopoulos B, Nehls B, Nikolettos N, Diedrich K, Al-Hasani S. Semen DNA fragmentation index, evaluated with both TUNEL and Comet assay, and the ICSI outcome. In Vivo 2007;21:1075-1080.
15. Check JH, Graziano V, Cohen R, Krotec J, Check ML. Effect of an abnormal sperm chromatin structural assay (SCSA) on pregnancy outcome following (IVF) with ICSI in previous IVF failures. Arch Androl 2005;51:121-124.
16. Collins JA, Barnhart KT, Schlegel PN. Do sperm DNA integrity tests predict pregnancy with in vitro fertilization? Fertil Steril 2008; 89:823-831.
17. Evenson D, Jost L. Sperm chromatin structure assay: DNA denaturability. Methods Cell Biol 1994;42:159-176.
18. Evenson D, Wixon R. Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay. Reprod Biomed Online 2006; 12:466-472.
19. Evenson DP, Jost LK, Marshall D, Zinaman MJ, Clegg E, Purvis K, De Angelis P, Claussen OP. Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod 1999;14:1039-1049.
20. Evenson DP, Larson KL, Jost LK. Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 2002; 23:25-43.
21. Fatehi AN, Bevers MM, Schoevers E, Roelen BAJ, Colenbrander B, Gadella BM. DNA damage in bovine sperm does not block fertilization and early embryonic development but induces apoptosis after the first cleavages. J Androl 2006;27:176-188.
22. Frydman N, Prisant N, Hesters L, Frydman R, Tachdjian G, Cohen-Bacrie P, Fanchin R. Adequate ovarian folicular status does not prevent the decrease in pregnancy rates associated with high sperm DNA fragmentation. Fertil Steril 2008;89:92-97.
23. Gandini L, Lombardo F, Paoli D, Caruso F, Eleuteri P, Leter G, Ciriminna R, Culasso F, Dondero F, Lenzi A et al. Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage. Hum Reprod 2004;19:1409-1417.
24. Gardner DK, Schoolcraft WB, Surrey ES, Stilley K, Stevens J, Evenson D. The sperm chromatin structure assay (SCSA) and its relationship to IVF outcome: a prospective trial. Fertil Steril 2004; 82(Suppl. 2):S192.
25. Greco E, Romano S, Iacobelli M, Ferrero S, Baroni E, Minasi MG, Ubaldi F, Rienzi L, Tesarik J. ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment. Hum Reprod 2005;20: 2590-2594.
26. Henkel R, Kierspel E, Hajimohammad M, Stalf T, Hoogendijk C, Mehnert C, Menkveld R, Schill W, Kruger TF. DNA fragmentation of spermatozoa and assisted reproduction technology. Reprod Biomed Online 2003;7:477-484.
27. Larson-Cook KL, Brannian JD, Hansen KA, Kasperson KM, Aamold BS, Evenson DP. Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay. Fertil Steril 2003;80: 895-902.
28. Li Z, Wang L, Cai J, Huang H. Correlation of sperm DNA damage with IVF and ICSI outcomes: a systematic review and meta-analysis. J Assist Reprod Genet 2006;23:367-376.
29. Lin M, Lee RK, Li S, Lu C, Sun F, Hwu Y. Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic sperm injection, but might be related to spontaneous abortion rates. Fertil Steril 2008;90:352-359.
30. Nicopoullos JDM, Gilling-Smith C, Almeida PA, Homa S, Norman-Taylor JQ, Ramsay JWA. Sperm DNA fragmentation in subfertile men: the effect on the outcome of intracytoplasmic sperm injection and correlation with sperm variables. BJU Int 2008; 101:1553-1560.
31. Payne JF, Raburn DJ, Couchman GM, Price TM, Jamison MG, Walmer DK. Redefining the relationship between sperm deoxyribonucleic acid fragmentation as measured by the sperm chromatin structure assay and outcomes of assisted reproductive techniques. Fertil Steril 2005; 84:356-364
32. Practice Committee of the American Society for Reproductive Medicine. Fertil Steril 2006;86(Suppl. 4):S35-S37.
33. Said TM, Agarwal A, Sharma RK, Thomas AJ Jr, Sikka SC. Impact of sperm morphology on DNA damage caused by oxidative stress induced by b-nicotinamide adenine dinucleotide phosphate. Fertil Steril 2005; 83:95-103.
34. Saleh RA, Agarwal A. Oxidative stress and male infertility: from research bench to clinical practice. J Androl 2002;23:737-752.
35. Seli E, Gardner DK, Schoolcraft WB, Moffatt O, Sakkas D. Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 2004; 82:378-383.
36. Spano M, Bonde JP, Hjollund HI, Kolstad HA, Cordelli E, Leter G. Sperm chromatin damage impairs human fertility. The Danish first pregnancy planner study team. Fertil Steril 2000;73:43-50.
37. Sun J, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 1997;56:602-607.
38. Tarozzi N, Bizzaro D, Flamigni C, Borini A. Clinical relevance of sperm DNA damage in assisted reproduction. Reprod Biomed Online 2007; 14:746-757.
39. Tesarik J. Paternal effects on cell division in the human preimplantation embryo. Reprod Biomed Online 2005;10:370-375.
40. Tesarik J, Kopecny V, Plachot M, Mandelbaum J, Da Lage C, Flechon J. Nucleologenesis in the human embryo developing in vitro: ultrastructural and autoradiographic analysis. Dev Biol 1986; 115:193-203.
41. Tesarik J, Greco E, Mendoza C. Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation. Hum Reprod 2004;19:611-615.
42. Virro MR, Larson-Cook KL, Evenson DP. Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing prgnancy in in vitro fertilization and intracytoplasmic sperm injection cycles. Fertil Steril 2004;81:1289-1295.
43. Zini A, Libman J. Sperm DNA damage: clinical significance in the era of assisted reproduction. CMAj 2006;175:495-500.
44. Zini A, Bielecki R, Phang D, Zenzes MT. Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril 2001;75:674-677.
45. Zini A, Meriano J, Kader K, Jarvi K, Laskin CA, Cadesky K. Potential adverse effect of sperm DNA damage on embryo quality after ICSI. Hum Reprod 2005;20:3476-3480.