-
1
-
-
0037429692
-
Trafficking of the ErbB receptors and its influence on signaling
-
Wiley H.S. Trafficking of the ErbB receptors and its influence on signaling. Exp. Cell Res. 2003, 284:78-88.
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 78-88
-
-
Wiley, H.S.1
-
2
-
-
2442701289
-
The ErbB/HER receptor protein-tyrosine kinases and cancer
-
Roskoski R. The ErbB/HER receptor protein-tyrosine kinases and cancer. Biochem. Biophys. Res. Commun. 2004, 319:1-11.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.319
, pp. 1-11
-
-
Roskoski, R.1
-
3
-
-
32044464123
-
Epidermal growth factor receptor (EGFR) signaling in cancer
-
Normanno N., De Luca A., Bianco C., Strizzi L., Mancino M., Maiello M.R., Carotenuto A., De Feo G., Caponigro F., Salomon D.S. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 2006, 366:2-16.
-
(2006)
Gene
, vol.366
, pp. 2-16
-
-
Normanno, N.1
De Luca, A.2
Bianco, C.3
Strizzi, L.4
Mancino, M.5
Maiello, M.R.6
Carotenuto, A.7
De Feo, G.8
Caponigro, F.9
Salomon, D.S.10
-
4
-
-
33746485766
-
Epidermal growth factor receptor targeting in cancer
-
Mendelsohn J., Baselga J. Epidermal growth factor receptor targeting in cancer. Semin. Oncol. 2006, 33:369-385.
-
(2006)
Semin. Oncol.
, vol.33
, pp. 369-385
-
-
Mendelsohn, J.1
Baselga, J.2
-
5
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn J., Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000, 19:6550-6565.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
6
-
-
0029025332
-
Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas
-
Wikstrand C.J., Hale L.P., Batra S.K., Hill M.L., Humphrey P.A., Kurpad S.N., McLendon R.E., Moscatello D., Pegram C.N., Reist C.J., et al. Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. Cancer Res. 1995, 55:3140-3148.
-
(1995)
Cancer Res.
, vol.55
, pp. 3140-3148
-
-
Wikstrand, C.J.1
Hale, L.P.2
Batra, S.K.3
Hill, M.L.4
Humphrey, P.A.5
Kurpad, S.N.6
McLendon, R.E.7
Moscatello, D.8
Pegram, C.N.9
Reist, C.J.10
-
7
-
-
0034799139
-
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor
-
Ciardiello F., Tortora G. A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin. Cancer Res. 2001, 7:2958-2970.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2958-2970
-
-
Ciardiello, F.1
Tortora, G.2
-
8
-
-
17444403242
-
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
-
Li S., Schmitz K.R., Jeffrey P.D., Wiltzius J.J., Kussie P., Ferguson K.M. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 2005, 7:301-311.
-
(2005)
Cancer Cell
, vol.7
, pp. 301-311
-
-
Li, S.1
Schmitz, K.R.2
Jeffrey, P.D.3
Wiltzius, J.J.4
Kussie, P.5
Ferguson, K.M.6
-
9
-
-
0035892346
-
ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression
-
Anderson N.G., Ahmad T., Chan K., Dobson R., Bundred N.J. ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression. Int. J. Cancer 2001, 94:774-782.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 774-782
-
-
Anderson, N.G.1
Ahmad, T.2
Chan, K.3
Dobson, R.4
Bundred, N.J.5
-
10
-
-
10344239413
-
Gefitinib - a novel targeted approach to treating cancer
-
Herbst R.S., Fukuoka M., Baselga J. Gefitinib - a novel targeted approach to treating cancer. Nat. Rev. Cancer 2004, 4:956-965.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 956-965
-
-
Herbst, R.S.1
Fukuoka, M.2
Baselga, J.3
-
11
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., Harris P.L., Haserlat S.M., Supko J.G., Haluska F.G., Louis D.N., Christiani D.C., Settleman J., Haber D.A. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 2004, 350:2129-2139.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
12
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., Herman P., Kaye F.J., Lindeman N., Boggon T.J., Naoki K., Sasaki H., Fujii Y., Eck M.J., Sellers W.R., Johnson B.E., Meyerson M. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
13
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
Takano T., Ohe Y., Sakamoto H., Tsuta K., Matsuno Y., Tateishi U., Yamamoto S., Nokihara H., Yamamoto N., Sekine I., Kunitoh H., Shibata T., Sakiyama T., Yoshida T., Tamura T. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J. Clin. Oncol. 2005, 23:6829-6837.
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
Tsuta, K.4
Matsuno, Y.5
Tateishi, U.6
Yamamoto, S.7
Nokihara, H.8
Yamamoto, N.9
Sekine, I.10
Kunitoh, H.11
Shibata, T.12
Sakiyama, T.13
Yoshida, T.14
Tamura, T.15
-
14
-
-
0030787340
-
Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)
-
Chu C.T., Everiss K.D., Wikstrand C.J., Batra S.K., Kung H.J., Bigner D.D. Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem. J. 1997, 324(Pt. 3):855-861.
-
(1997)
Biochem. J.
, vol.324
, Issue.PART 3
, pp. 855-861
-
-
Chu, C.T.1
Everiss, K.D.2
Wikstrand, C.J.3
Batra, S.K.4
Kung, H.J.5
Bigner, D.D.6
-
15
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S., Boggon T.J., Dayaram T., Janne P.A., Kocher O., Meyerson M., Johnson B.E., Eck M.J., Tenen D.G., Halmos B. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 2005, 352:786-792.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Janne, P.A.4
Kocher, O.5
Meyerson, M.6
Johnson, B.E.7
Eck, M.J.8
Tenen, D.G.9
Halmos, B.10
-
16
-
-
40049099220
-
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
-
Yun C.H., Mengwasser K.E., Toms A.V., Woo M.S., Greulich H., Wong K.K., Meyerson M., Eck M.J. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc. Natl. Acad. Sci. USA 2008, 105:2070-2075.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2070-2075
-
-
Yun, C.H.1
Mengwasser, K.E.2
Toms, A.V.3
Woo, M.S.4
Greulich, H.5
Wong, K.K.6
Meyerson, M.7
Eck, M.J.8
-
17
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W., Miller V.A., Politi K.A., Riely G.J., Somwar R., Zakowski M.F., Kris M.G., Varmus H. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med. 2005, 2:e73.
-
(2005)
PLoS Med.
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
Kris, M.G.7
Varmus, H.8
-
18
-
-
28444478439
-
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants
-
Greulich H., Chen T.H., Feng W., Janne P.A., Alvarez J.V., Zappaterra M., Bulmer S.E., Frank D.A., Hahn W.C., Sellers W.R., Meyerson M. Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. PLoS Med. 2005, 2:e313.
-
(2005)
PLoS Med.
, vol.2
-
-
Greulich, H.1
Chen, T.H.2
Feng, W.3
Janne, P.A.4
Alvarez, J.V.5
Zappaterra, M.6
Bulmer, S.E.7
Frank, D.A.8
Hahn, W.C.9
Sellers, W.R.10
Meyerson, M.11
-
19
-
-
0032912817
-
Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail
-
Bishayee A., Beguinot L., Bishayee S. Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail. Mol. Biol. Cell 1999, 10:525-536.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 525-536
-
-
Bishayee, A.1
Beguinot, L.2
Bishayee, S.3
-
20
-
-
0026756438
-
Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries
-
Matuoka K., Shibata M., Yamakawa A., Takenawa T. Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries. Proc. Natl. Acad. Sci. USA 1992, 89:9015-9019.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9015-9019
-
-
Matuoka, K.1
Shibata, M.2
Yamakawa, A.3
Takenawa, T.4
-
21
-
-
77954167742
-
Basic study on SH2 domain of Grb2 as a molecular probe for detection of RTK activation
-
Saito Y., Furukawa T., Arano Y., Fujibayashi Y., Saga T. Basic study on SH2 domain of Grb2 as a molecular probe for detection of RTK activation. Int. J. Oncol. 2010, 37:281-287.
-
(2010)
Int. J. Oncol.
, vol.37
, pp. 281-287
-
-
Saito, Y.1
Furukawa, T.2
Arano, Y.3
Fujibayashi, Y.4
Saga, T.5
-
22
-
-
33646489207
-
Cytoplasmic transduction peptide (CTP): new approach for the delivery of biomolecules into cytoplasm in vitro and in vivo
-
Kim D., Jeon C., Kim J.H., Kim M.S., Yoon C.H., Choi I.S., Kim S.H., Bae Y.S. Cytoplasmic transduction peptide (CTP): new approach for the delivery of biomolecules into cytoplasm in vitro and in vivo. Exp. Cell Res. 2006, 312:1277-1288.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 1277-1288
-
-
Kim, D.1
Jeon, C.2
Kim, J.H.3
Kim, M.S.4
Yoon, C.H.5
Choi, I.S.6
Kim, S.H.7
Bae, Y.S.8
-
23
-
-
0033520487
-
In vivo protein transduction: delivery of a biologically active protein into the mouse
-
Schwarze S.R., Ho A., Vocero-Akbani A., Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999, 285:1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
24
-
-
33645751057
-
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide
-
Tan M., Lan K.H., Yao J., Lu C.H., Sun M., Neal C.L., Lu J., Yu D. Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide. Cancer Res. 2006, 66:3764-3772.
-
(2006)
Cancer Res.
, vol.66
, pp. 3764-3772
-
-
Tan, M.1
Lan, K.H.2
Yao, J.3
Lu, C.H.4
Sun, M.5
Neal, C.L.6
Lu, J.7
Yu, D.8
-
25
-
-
33646678222
-
Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment
-
Harada H., Kizaka-Kondoh S., Hiraoka M. Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment. Breast Cancer 2006, 13:16-26.
-
(2006)
Breast Cancer
, vol.13
, pp. 16-26
-
-
Harada, H.1
Kizaka-Kondoh, S.2
Hiraoka, M.3
-
26
-
-
71049134493
-
A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFkappaB activity
-
Sorriento D., Campanile A., Santulli G., Leggiero E., Pastore L., Trimarco B., Iaccarino G. A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFkappaB activity. Mol. Cancer 2009, 8:97.
-
(2009)
Mol. Cancer
, vol.8
, pp. 97
-
-
Sorriento, D.1
Campanile, A.2
Santulli, G.3
Leggiero, E.4
Pastore, L.5
Trimarco, B.6
Iaccarino, G.7
-
27
-
-
33748648777
-
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells
-
Tunnemann G., Martin R.M., Haupt S., Patsch C., Edenhofer F., Cardoso M.C. Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J. 2006, 20:1775-1784.
-
(2006)
FASEB J.
, vol.20
, pp. 1775-1784
-
-
Tunnemann, G.1
Martin, R.M.2
Haupt, S.3
Patsch, C.4
Edenhofer, F.5
Cardoso, M.C.6
-
28
-
-
0032880670
-
Selective GRB2 SH2 inhibitors as anti-Ras therapy
-
Gay B., Suarez S., Caravatti G., Furet P., Meyer T., Schoepfer J. Selective GRB2 SH2 inhibitors as anti-Ras therapy. Int. J. Cancer 1999, 83:235-241.
-
(1999)
Int. J. Cancer
, vol.83
, pp. 235-241
-
-
Gay, B.1
Suarez, S.2
Caravatti, G.3
Furet, P.4
Meyer, T.5
Schoepfer, J.6
-
29
-
-
34447126344
-
Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase
-
Li N., Lorinczi M., Ireton K., Elferink L.A. Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase. J. Biol. Chem. 2007, 282:16764-16775.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16764-16775
-
-
Li, N.1
Lorinczi, M.2
Ireton, K.3
Elferink, L.A.4
-
30
-
-
0842308379
-
Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells
-
Katterle Y., Brandt B.H., Dowdy S.F., Niggemann B., Zanker K.S., Dittmar T. Antitumour effects of PLC-gamma1-(SH2)2-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells. Br. J. Cancer 2004, 90:230-235.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 230-235
-
-
Katterle, Y.1
Brandt, B.H.2
Dowdy, S.F.3
Niggemann, B.4
Zanker, K.S.5
Dittmar, T.6
|