메뉴 건너뛰기




Volumn 68, Issue 12, 2006, Pages 1257-1267

Progression of the dose-related effects of estrogenic endocrine disruptors, an important factor in declining fertility, differs between the hypothalamo-pituitary axis and reproductive organs of male mice

Author keywords

Diethylstilbestrol (DES); Endocrine disruptors; Fertility rate; Fetal and or neonatal exposure; Steroidogenic acute regulatory protein (StAR)

Indexed keywords

DIETHYLSTILBESTROL; ESTROGEN;

EID: 33846273518     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.68.1257     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 0020973422 scopus 로고
    • Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals
    • Arai, Y., Mori, T., Suzuki, Y. and Bern, H. A. 1983. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. Int. Rev. Cytol. 84: 235-268.
    • (1983) Int. Rev. Cytol , vol.84 , pp. 235-268
    • Arai, Y.1    Mori, T.2    Suzuki, Y.3    Bern, H.A.4
  • 2
    • 0033752233 scopus 로고    scopus 로고
    • Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: Evidence for stimulatory effects of low estrogen levels
    • Atanassova, N., McKinnell, C., Turner, K. J., Walker, M., Fisher, J. S., Morley, M., Millar, M. R., Groome, N. P. and Sharpe, R. M. 2000. Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: Evidence for stimulatory effects of low estrogen levels. Endocrinology 141: 3898-3907.
    • (2000) Endocrinology , vol.141 , pp. 3898-3907
    • Atanassova, N.1    McKinnell, C.2    Turner, K.J.3    Walker, M.4    Fisher, J.S.5    Morley, M.6    Millar, M.R.7    Groome, N.P.8    Sharpe, R.M.9
  • 3
    • 0033303787 scopus 로고    scopus 로고
    • Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood
    • Atanassova, N., Mckinnell, C., Walker, M., Turner, K. J., Fisher, J. S., Morley, M., Millar, M. R., Groome, N. P. and Sharpe, R. M. 1999. Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood. Endocrinology 140: 5364-5373.
    • (1999) Endocrinology , vol.140 , pp. 5364-5373
    • Atanassova, N.1    Mckinnell, C.2    Walker, M.3    Turner, K.J.4    Fisher, J.S.5    Morley, M.6    Millar, M.R.7    Groome, N.P.8    Sharpe, R.M.9
  • 4
    • 0026718180 scopus 로고
    • Exogenously administered testosterone maintains spermatogenesis quantitatively in adult rats actively immunized against gonadotropin-releasing hormone
    • Awoniyi, C. A., Zirkin, B. R., Chandrashekar, V. and Schlaff, W. D. 1992. Exogenously administered testosterone maintains spermatogenesis quantitatively in adult rats actively immunized against gonadotropin-releasing hormone. Endocrinology 130: 3283-3288.
    • (1992) Endocrinology , vol.130 , pp. 3283-3288
    • Awoniyi, C.A.1    Zirkin, B.R.2    Chandrashekar, V.3    Schlaff, W.D.4
  • 5
    • 0025109959 scopus 로고
    • Possible role of changes in post-natal gonadotrophin concentrations on permanent impairment of the reproductive system in neonatally oestrogenized male rats
    • Bellido, C., Pinilla, L., Aguilar, R., Gaytan, F. and Aguilar, E. 1990. Possible role of changes in post-natal gonadotrophin concentrations on permanent impairment of the reproductive system in neonatally oestrogenized male rats. J. Reprod. Fertil. 90: 369-374.
    • (1990) J. Reprod. Fertil , vol.90 , pp. 369-374
    • Bellido, C.1    Pinilla, L.2    Aguilar, R.3    Gaytan, F.4    Aguilar, E.5
  • 6
    • 0028104418 scopus 로고
    • The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
    • Clark, B. J., Wells, J., King, S. R. and Stocco, D. M. 1994. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J. Biol. Chem. 269: 28314-28322.
    • (1994) J. Biol. Chem , vol.269 , pp. 28314-28322
    • Clark, B.J.1    Wells, J.2    King, S.R.3    Stocco, D.M.4
  • 7
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn, T., vom Saal, F. S. and Soto, A. M. 1993. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 101: 378-384.
    • (1993) Environ. Health Perspect , vol.101 , pp. 378-384
    • Colborn, T.1    vom Saal, F.S.2    Soto, A.M.3
  • 9
    • 0029969771 scopus 로고    scopus 로고
    • Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility
    • Eddy, E. M., Washburn, T. F., Bunch, D. O., Goulding, E. H., Gladen, B. C., Lubahn, D. B. and Korach, K. S. 1996. Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 137: 4796-4805.
    • (1996) Endocrinology , vol.137 , pp. 4796-4805
    • Eddy, E.M.1    Washburn, T.F.2    Bunch, D.O.3    Goulding, E.H.4    Gladen, B.C.5    Lubahn, D.B.6    Korach, K.S.7
  • 10
    • 0022577334 scopus 로고
    • Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells
    • Gaytan, F., Pinilla, L., Aguilar, R., Lucena, M. C. and Paniagua, R. 1986. Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells. J. Androl. 7: 112-121.
    • (1986) J. Androl , vol.7 , pp. 112-121
    • Gaytan, F.1    Pinilla, L.2    Aguilar, R.3    Lucena, M.C.4    Paniagua, R.5
  • 11
    • 0035113688 scopus 로고    scopus 로고
    • Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology
    • Goyal, H. O., Braden, T. D., Mansour, M., Williams, C. S., Kamaleldin, A. and Srivastava, K. K. 2001. Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology. Biol. Reprod. 64: 927-934.
    • (2001) Biol. Reprod , vol.64 , pp. 927-934
    • Goyal, H.O.1    Braden, T.D.2    Mansour, M.3    Williams, C.S.4    Kamaleldin, A.5    Srivastava, K.K.6
  • 14
    • 0024773107 scopus 로고
    • Reproductive and general metabolic effects of phytoestrogens in mammals
    • Kaldas, R. S. and Hughes, C. L. Jr. 1989. Reproductive and general metabolic effects of phytoestrogens in mammals. Reprod. Toxicol. 3: 81-89.
    • (1989) Reprod. Toxicol , vol.3 , pp. 81-89
    • Kaldas, R.S.1    Hughes Jr., C.L.2
  • 16
    • 0034921893 scopus 로고    scopus 로고
    • From malformations to molecular mechanisms in the male: Three decades of research on endocrine disrupters
    • McLachlan, J. A., Newbold, R. R., Burow, M. E. and Li, S. F. 2001. From malformations to molecular mechanisms in the male: Three decades of research on endocrine disrupters. APMIS. 109: 263-272.
    • (2001) APMIS , vol.109 , pp. 263-272
    • McLachlan, J.A.1    Newbold, R.R.2    Burow, M.E.3    Li, S.F.4
  • 17
    • 0031935689 scopus 로고    scopus 로고
    • Are estrogens carcinogenic during development of testis?
    • McLachlan, J. A., Newblod, R. R., Li, S. F. and Negishi, M. 1998. Are estrogens carcinogenic during development of testis? APMIS. 106: 240-244.
    • (1998) APMIS , vol.106 , pp. 240-244
    • McLachlan, J.A.1    Newblod, R.R.2    Li, S.F.3    Negishi, M.4
  • 18
    • 0026556363 scopus 로고
    • Sensitivity of the vagina and uterus of mice neonatally exposed to estrogen or androgen to postnatal treatment with estrogen or androgen
    • Mori, T., Mills, K. T. and Bern, H. A. 1992. Sensitivity of the vagina and uterus of mice neonatally exposed to estrogen or androgen to postnatal treatment with estrogen or androgen. Proc. Soc. Exp. Biol. Med. 199: 466-469.
    • (1992) Proc. Soc. Exp. Biol. Med , vol.199 , pp. 466-469
    • Mori, T.1    Mills, K.T.2    Bern, H.A.3
  • 19
    • 0021220861 scopus 로고
    • Testicular carcinoma in situ in children with the androgen insensitivity (testicular feminisation) syndrome
    • Müller, J. and Skakkebæk, N. E. 1984. Testicular carcinoma in situ in children with the androgen insensitivity (testicular feminisation) syndrome. Br. Med. J. (Clin Res Ed) 288: 1419-1420.
    • (1984) Br. Med. J. (Clin Res Ed) , vol.288 , pp. 1419-1420
    • Müller, J.1    Skakkebæk, N.E.2
  • 20
    • 0031711585 scopus 로고    scopus 로고
    • Increased tumors but uncompromised fertility in the female descendants of mice exposed developmentally to diethylstilbestrol
    • Newblod, R. R., Hanson, R. B., Jefferson, W. N., Bullock, B. C., Haseman, J. and McLachlan, J. A. 1998. Increased tumors but uncompromised fertility in the female descendants of mice exposed developmentally to diethylstilbestrol. Carcinogenesis 19: 1655-1663.
    • (1998) Carcinogenesis , vol.19 , pp. 1655-1663
    • Newblod, R.R.1    Hanson, R.B.2    Jefferson, W.N.3    Bullock, B.C.4    Haseman, J.5    McLachlan, J.A.6
  • 21
    • 0028868502 scopus 로고
    • Steroid synthesis in testicular and ovarian homogenates from adult mice treated neonatally with diethylstilbestrol
    • Ohta, Y., Uesugi, Y. and Iguchi, T. 1995. Steroid synthesis in testicular and ovarian homogenates from adult mice treated neonatally with diethylstilbestrol. Med. Sci. Res. 23: 763-764.
    • (1995) Med. Sci. Res , vol.23 , pp. 763-764
    • Ohta, Y.1    Uesugi, Y.2    Iguchi, T.3
  • 22
    • 0034043572 scopus 로고    scopus 로고
    • Localization of estrogen receptor a, estrogen receptor β and androgen receptors in the rat reproductive organ
    • Pelletier, G., Labrie, C. and Labrie, F. 2000. Localization of estrogen receptor a, estrogen receptor β and androgen receptors in the rat reproductive organ. J. Endocrinol. 165: 359-370.
    • (2000) J. Endocrinol , vol.165 , pp. 359-370
    • Pelletier, G.1    Labrie, C.2    Labrie, F.3
  • 23
    • 0344286131 scopus 로고    scopus 로고
    • Changes in the number, proliferation rate and bcl-2 protein immunoexpression of epithelial and periductal cells from rat epididymis during postnatal development
    • Ramirez, R., Martin, R., Martin, J. J., Ramirez, J. R., Paniagua, R. and Santamaria, L. 1999. Changes in the number, proliferation rate and bcl-2 protein immunoexpression of epithelial and periductal cells from rat epididymis during postnatal development. J. Androl. 20: 702-712.
    • (1999) J. Androl , vol.20 , pp. 702-712
    • Ramirez, R.1    Martin, R.2    Martin, J.J.3    Ramirez, J.R.4    Paniagua, R.5    Santamaria, L.6
  • 24
    • 0027232797 scopus 로고
    • Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?
    • Sharpe, R. M. and Skakkebæk, N. E. 1993. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 341: 1392-1395.
    • (1993) Lancet , vol.341 , pp. 1392-1395
    • Sharpe, R.M.1    Skakkebæk, N.E.2
  • 25
    • 0031793912 scopus 로고    scopus 로고
    • Abnormalities in functional development of the Sertoli cells in rats treated neonatally with diethylstilbestrol: A possible role for estrogens in Sertoli cell development
    • Sharpe, R. M., Atanassova, N., McKinnell, C., Parte, P., Turner, K. J., Fisher, J. S., Kerr, J. B., Groome, N. P., Macpherson, S., Millar, M. R. and Saunders, P. T. 1998. Abnormalities in functional development of the Sertoli cells in rats treated neonatally with diethylstilbestrol: A possible role for estrogens in Sertoli cell development. Biol. Reprod. 59: 1084-1094.
    • (1998) Biol. Reprod , vol.59 , pp. 1084-1094
    • Sharpe, R.M.1    Atanassova, N.2    McKinnell, C.3    Parte, P.4    Turner, K.J.5    Fisher, J.S.6    Kerr, J.B.7    Groome, N.P.8    Macpherson, S.9    Millar, M.R.10    Saunders, P.T.11
  • 26
    • 0029551645 scopus 로고
    • Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production
    • Sharpe, R. M., Fisher, J. S., Millar, M. M., Jobling, S. and Sumpter, J. P. 1995. Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production. Environ. Health Perspect. 103: 1136-1143.
    • (1995) Environ. Health Perspect , vol.103 , pp. 1136-1143
    • Sharpe, R.M.1    Fisher, J.S.2    Millar, M.M.3    Jobling, S.4    Sumpter, J.P.5
  • 27
    • 0026589413 scopus 로고
    • Testosterone and spermatogenesis. Identification of stagespecific, androgen-regulated proteins secreted by adult rat seminiferous tubules
    • Sharpe, R. M., Maddocks, S., Millar, M., Kerr, J. B., Saunders, P. T. and McKinnell, C. 1992. Testosterone and spermatogenesis. Identification of stagespecific, androgen-regulated proteins secreted by adult rat seminiferous tubules. J. Androl. 13: 172-184.
    • (1992) J. Androl , vol.13 , pp. 172-184
    • Sharpe, R.M.1    Maddocks, S.2    Millar, M.3    Kerr, J.B.4    Saunders, P.T.5    McKinnell, C.6
  • 28
    • 0035675262 scopus 로고    scopus 로고
    • Neonatal exposure to genistein reduces expression of estrogen receptor alpha and androgen receptor in testes of adult mice
    • Shibayama, T., Fukata, H., Sakurai, K., Adachi, T., Komiyama, M., Iguchi, T. and Mori, C. 2001. Neonatal exposure to genistein reduces expression of estrogen receptor alpha and androgen receptor in testes of adult mice. Endocr. J. 48: 655-663.
    • (2001) Endocr. J , vol.48 , pp. 655-663
    • Shibayama, T.1    Fukata, H.2    Sakurai, K.3    Adachi, T.4    Komiyama, M.5    Iguchi, T.6    Mori, C.7
  • 29
    • 0029030626 scopus 로고
    • Human steroidogenic acute regulatory protein: Functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13
    • Sugawara, T., Holt, J. A., Driscoll, D., Strauss, J. F. 3rd., Lin, D., Miller, W. L., Patterson, D., Clancy, K. P., Hart, I. M., Clark, B. J. and Stocco, D. M. 1995. Human steroidogenic acute regulatory protein: Functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13. Proc. Natl. Acad. Sci. U.S.A. 92: 4778-4782.
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 4778-4782
    • Sugawara, T.1    Holt, J.A.2    Driscoll, D.3    Strauss, J.F.4    Lin, D.5    Miller, W.L.6    Patterson, D.7    Clancy, K.P.8    Hart, I.M.9    Clark, B.J.10    Stocco, D.M.11
  • 30
    • 0028819993 scopus 로고    scopus 로고
    • Sugawara, T., Lin, D., Holt, J. A., Martin, K. O., Javitt, N. B., Miller, W. L. and Strauss, J. F. 3rd. 1995. Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 34: 12506-12512.
    • Sugawara, T., Lin, D., Holt, J. A., Martin, K. O., Javitt, N. B., Miller, W. L. and Strauss, J. F. 3rd. 1995. Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 34: 12506-12512.
  • 32
    • 0018381505 scopus 로고
    • Development of cell types and regional differences in the postnatal rat epididymis
    • Sun, E. L. and Flickinger, C. J. 1979. Development of cell types and regional differences in the postnatal rat epididymis. Am. J. Anat. 154: 27-55.
    • (1979) Am. J. Anat , vol.154 , pp. 27-55
    • Sun, E.L.1    Flickinger, C.J.2
  • 33
    • 0019949807 scopus 로고
    • Proliferative activity in the rat epididymis during postnatal development
    • Sun, E. L. and Flickinger, C. J. 1982. Proliferative activity in the rat epididymis during postnatal development. Anat. Rec. 203: 273-284.
    • (1982) Anat. Rec , vol.203 , pp. 273-284
    • Sun, E.L.1    Flickinger, C.J.2
  • 35
    • 0035059232 scopus 로고    scopus 로고
    • Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat
    • Toyama, Y., Ohkawa, M., Oku, R., Maekawa, M. and Yuasa, S. 2001. Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat. J. Androl. 22: 413-423.
    • (2001) J. Androl , vol.22 , pp. 413-423
    • Toyama, Y.1    Ohkawa, M.2    Oku, R.3    Maekawa, M.4    Yuasa, S.5
  • 36
    • 0141456194 scopus 로고    scopus 로고
    • Expression of steroidogenic acute regulatory protein (StAR) and LH receptor in MA-10 cells
    • Tsuchiya, M., Inoue, K., Matsuda, H., Nakamura, K., Mizutani, T., Miyamoto, K. and Minegishi, T. 2003. Expression of steroidogenic acute regulatory protein (StAR) and LH receptor in MA-10 cells. Life Sci. 73: 2855-2863.
    • (2003) Life Sci , vol.73 , pp. 2855-2863
    • Tsuchiya, M.1    Inoue, K.2    Matsuda, H.3    Nakamura, K.4    Mizutani, T.5    Miyamoto, K.6    Minegishi, T.7
  • 38
    • 0027690440 scopus 로고
    • Purified methoxychlor stimulates the reproductive tract in immature female mice
    • Walters, L. M., Rourke, A. W. and Eroschenko, V. P. 1993. Purified methoxychlor stimulates the reproductive tract in immature female mice. Reprod. Toxicol. 7: 599-606.
    • (1993) Reprod. Toxicol , vol.7 , pp. 599-606
    • Walters, L.M.1    Rourke, A.W.2    Eroschenko, V.P.3
  • 39
    • 0035002848 scopus 로고    scopus 로고
    • Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: Evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man
    • Williams, K., McKinnell, C., Saunders, P. T., Walker, M., Fisher, J. S., Turner, K. J., Atanassova, N. and Sharpe, R. M. 2001. Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man. Hum. Reprod. Update 7: 236-247.
    • (2001) Hum. Reprod. Update , vol.7 , pp. 236-247
    • Williams, K.1    McKinnell, C.2    Saunders, P.T.3    Walker, M.4    Fisher, J.S.5    Turner, K.J.6    Atanassova, N.7    Sharpe, R.M.8
  • 40
    • 0032130798 scopus 로고    scopus 로고
    • Spermatogenesis: Its regulation by testosterone and FSH
    • Zirkin, B. R. 1998. Spermatogenesis: its regulation by testosterone and FSH. Semin. Cell Dev. Biol. 9: 417-421.
    • (1998) Semin. Cell Dev. Biol , vol.9 , pp. 417-421
    • Zirkin, B.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.