A longitudinal study of uremic pruritus in hemodialysis patients

Clinical Journal of the American Society of Nephrology

Volumn 5, Issue 8, 2010, Pages 1410-1419

  Mathur, Vandana S ^a   Lindberg, Jill ^b   Germain, Michael ^c   Block, Geoffrey ^d   Tumlin, James ^e,g   Smith, Mark ^f   Grewal, Mandeep ^g   McGuire, Dawn ^a  

^a Acologix Inc   (United States)

^b New Orleans Nephrology Associates   (United States)

^c Western New England Renal and Transplant Associates   (United States)

^d Denver Nephrology   (United States)

^e Southeastern Nephrology Associates   (United States)

^f Kidney Care Associates   (United States)

^g UNIVERSITY OF TENNESSEE AT CHATTANOOGA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; ANTIHISTAMINIC AGENT; CORTICOSTEROID; EMOLLIENT AGENT; GABAPENTIN; NALTREXONE; OPIATE; SEDATIVE AGENT; STEROID; TACROLIMUS;

ADULT; ARTICLE; CLINICAL ASSESSMENT; DISEASE SEVERITY; FEMALE; HEMODIALYSIS PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MOOD; OUTCOME ASSESSMENT; QUALITY OF LIFE; SKIN PRURITUS; SLEEP; SOCIAL INTERACTION; UREMIC PRURITUS; VALIDATION STUDY;

ADULT; ANTIPRURITICS; CHI-SQUARE DISTRIBUTION; COST OF ILLNESS; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; LINEAR MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PRURITUS; QUALITY OF LIFE; QUESTIONNAIRES; REGISTRIES; RENAL DIALYSIS; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; UREMIA;

EID: 77955730817     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.00100110     Document Type: Article

References (22)

1. Pisoni RL, Wikstrom B, Elder SJ, Akizawa T, Asano Y, Keen ML, Saran R, Mendelssohn DC, Young EW, Port FK: Pruritus in haemodialysis patients: International results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant 21: 3495-3505, 2006 (Pubitemid 44817100)
2. Ikoma A, Rukwied R, Stander S, Steinhoff M, Miyachi Y, Schmelz M: Neurophysiology of pruritus: Interaction of itch and pain. Arch Dermatol 139: 1475-1478, 2003
3. Bhaduri S, Mathur V, Fellmann J, Rosen, D: Uremic pruritus patients: A national survey of sleep and mood disruptions [Abstract]. Am J Kidney Dis 49: B31, 2007
4. Dar NR, Akhter A: Clinical characteristics of uremic pruritus in patients undergoing haemodialysis. J Coll Physicians Surg Pak 16: 94-96, 2006
5. Szepietowski JC, Szepietowski T, Reich A: Efficacy and tolerance of the cream containing structured physiological lipids with endocannabinoids in the treatment of uremic pruritus: A preliminary study. Acta Dermatovenerol Croat 13: 97-103, 2005
6. Chen YC, Chiu WT, Wu MS: Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. Am J Kidney Dis 48: 69-76, 2006
7. Manenti L, Vaglio A, Costantino E, Danisi D, Oliva B, Pini S, Prati E, Testori A: Gabapentin in the treatment of uremic itch: An index case and a pilot evaluation. J Nephrol 18: 86-91, 2005
8. Okada K, Matsumoto K: Effect of skin care with an emollient containing a high water content on mild uremic pruritus. Ther Apher Dial 8: 419-422, 2004
9. Legroux-Crespel E, Cledes J, Misery L: A comparative study on the effects of naltrexone and loratadine on uremic pruritus. Dermatology 208: 326-330, 2004
10. Pauli-Magnus C, Mikus G, Alscher DM, Kirschner T, Nagel W, Gugeler N, Risler T, Berger ED, Kuhlmann U, Mettang T: Naltrexone does not relieve uremic pruritus: Results of a randomized, double-blind, placebo-controlled crossover study. J Am Soc Nephrol 11: 514-519, 2000
11. Ashmore SD, Jones CH, Newstead CG, Daly MJ, Chrystyn H: Ondansetron therapy for uremic pruritus in hemodialysis patients. Am J Kidney Dis 35: 827-831, 2000
12. Duque MI, Yosipovitch G, Fleischer AB Jr., Willard J, Freedman BI: Lack of efficacy of tacrolimus ointment 0.1% for treatment of hemodialysis-related pruritus: a randomized, double-blind, vehicle-controlled study. J Am Acad Dermatol 52: 519-521, 2005
13. Bennett MI, Simpson KH: Gabapentin in the treatment of neuropathic pain. Palliat Med 18: 5-11, 2004
14. Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D: Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment. Eur J Pain 10: 287-333, 2006
15. McReynolds TM, Sheridan BJ: Intramuscular ketorolac versus osteopathic manipulative treatment in the management of acute neck pain in the emergency department: a randomized clinical trial. J Am Osteopath Assoc 105: 57-68, 2005
16. Yosipovitch G, Zucker I, Boner G, Gafter U, Shapira Y, David M: A questionnaire for the assessment of pruritus: Validation in uremic patients. Acta Derm Venereol 81: 108-111, 2001
17. Ross JR, Goller K, Hardy J, Riley J, Broadley K, A'Hern R, Williams J: Gabapentin is effective in the treatment of cancer-related neuropathic pain: A prospective, open-label study. J Palliat Med 8: 1118-1126, 2005
18. Hays RD, Stewart, AL: Sleep measures. In: Measuring Functioning and Well-Being: The Medical Outcomes Study Approach, edited by Stewart AL, Ware JE, Durham, NC, Duke University Press, 1992, pp 235-259
19. Watnick S, Wang PL, Demadura T, Ganzini L: Validation of 2 depression screening tools in dialysis patients. Am J Kidney Dis 46: 919-924, 2005
20. Duque MI, Thevarajah S, Chan YH, Tuttle AB, Freedman BI, Yosipovitch G: Uremic pruritus is associated with higher kt/V and serum calcium concentration. Clin Nephrol 66: 184-191, 2006
21. Zucker I, Yosipovitch G, David M, Gafter U, Boner G: Prevalence and characterization of uremic pruritus in patients undergoing hemodialysis: Uremic pruritus is still a major problem for patients with end-stage renal disease. J Am Acad Dermatol 49: 842-846, 2003
22. Weisbord SD, Fried LF, Arnold RM, Fine MJ, Levenson DJ, Peterson RA, Switzer GE: Prevalence, severity, and importance of physical and emotional symptoms in chronic hemodialysis patients. J Am Soc Nephrol 16: 2487-2494, 2005