메뉴 건너뛰기




Volumn 1, Issue 3, 2010, Pages 113-122

The fatty acid synthase fasn-1 acts upstream of WNK and ste20/GCK-VI kinases to modulate antimicrobial peptide expression in C. elegans epidermis

Author keywords

Genetics; Homeostasis; Innate immunity; Model organism; Signalling

Indexed keywords

FATTY ACID SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN KINASE WNK1; PROTEIN NLP 29; UNCLASSIFIED DRUG;

EID: 77955718770     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.1.3.10974     Document Type: Article
Times cited : (45)

References (33)
  • 1
    • 77955725295 scopus 로고    scopus 로고
    • Interactions with microbial pathogens
    • The C. elegans Research Community, ed. WormBook: WormBook
    • Darby C. Interactions with microbial pathogens. In: The C. elegans Research Community, ed. WormBook: WormBook.
    • Darby, C.1
  • 2
    • 45549095755 scopus 로고    scopus 로고
    • Models of Caenorhabditis elegans Infection by Bacterial and Fungal Pathogens
    • Ewbank J, Vivier E, eds. Methods Mol Biol: Humana Press
    • Powell JR, Ausubel FM. Models of Caenorhabditis elegans Infection by Bacterial and Fungal Pathogens. In: Ewbank J, Vivier E, eds. Methods Mol Biol: Humana Press 2008; 403-427.
    • (2008) , pp. 403-427
    • Powell, J.R.1    Ausubel, F.M.2
  • 3
    • 0037118055 scopus 로고    scopus 로고
    • Caenorhabditis elegans: Plague bacteria biofilm blocks food intake
    • Darby C, Hsu JW, Ghori N, Falkow S. Caenorhabditis elegans: plague bacteria biofilm blocks food intake. Nature 2002; 417:243-244.
    • (2002) Nature , vol.417 , pp. 243-244
    • Darby, C.1    Hsu, J.W.2    Ghori, N.3    Falkow, S.4
  • 4
    • 0036073326 scopus 로고    scopus 로고
    • Diverse Bacteria Are Pathogens of Caenorhabditis elegans
    • Couillault C, Ewbank JJ. Diverse Bacteria Are Pathogens of Caenorhabditis elegans. Infect Immun 2002; 70:4705-4707.
    • (2002) Infect Immun , vol.70 , pp. 4705-4707
    • Couillault, C.1    Ewbank, J.J.2
  • 5
    • 0034649644 scopus 로고    scopus 로고
    • A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans
    • Hodgkin J, Kuwabara PE, Corneliussen B. A novel bacterial pathogen, Microbacterium nematophilum, induces morphological change in the nematode C. elegans. Curr Biol 2000; 10:1615-1618.
    • (2000) Curr Biol , vol.10 , pp. 1615-1618
    • Hodgkin, J.1    Kuwabara, P.E.2    Corneliussen, B.3
  • 6
    • 0345678007 scopus 로고
    • Ultrastructural study of adhesion and initial stages of infection of the nematode by conidia of Drechmeria coniospora
    • Dijksterhuis J, Veenhuis M, Harder W. Ultrastructural study of adhesion and initial stages of infection of the nematode by conidia of Drechmeria coniospora. Mycological research 1990; 94:1-8.
    • (1990) Mycological Research , vol.94 , pp. 1-8
    • Dijksterhuis, J.1    Veenhuis, M.2    Harder, W.3
  • 7
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, et al. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat Immunol 2004; 5:488-494.
    • (2004) Nat Immunol , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5    Kohara, Y.6
  • 8
    • 48249137383 scopus 로고    scopus 로고
    • Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides
    • Pujol N, Zugasti O, Wong D, Couillault C, Kurz CL, Schulenburg H, et al. Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides. PLoS Pathog 2008; 4:1000105.
    • (2008) PLoS Pathog , vol.4 , pp. 1000105
    • Pujol, N.1    Zugasti, O.2    Wong, D.3    Couillault, C.4    Kurz, C.L.5    Schulenburg, H.6
  • 9
    • 41549104500 scopus 로고    scopus 로고
    • Distinct innate immune responses to infection and wounding in the C. elegans epidermis
    • Pujol N, Cypowyj S, Ziegler K, Millet A, Astrain A, Goncharov A, et al. Distinct innate immune responses to infection and wounding in the C. elegans epidermis. Curr Biol 2008; 18:481-489.
    • (2008) Curr Biol , vol.18 , pp. 481-489
    • Pujol, N.1    Cypowyj, S.2    Ziegler, K.3    Millet, A.4    Astrain, A.5    Goncharov, A.6
  • 10
    • 64649085452 scopus 로고    scopus 로고
    • Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade
    • Ziegler K, Kurz CL, Cypowyj S, Couillault C, Pophillat M, Pujol N, et al. Antifungal innate immunity in C. elegans: PKCdelta links G protein signaling and a conserved p38 MAPK cascade. Cell Host Microbe 2009; 5:341-352.
    • (2009) Cell Host Microbe , vol.5 , pp. 341-352
    • Ziegler, K.1    Kurz, C.L.2    Cypowyj, S.3    Couillault, C.4    Pophillat, M.5    Pujol, N.6
  • 11
    • 33747083190 scopus 로고    scopus 로고
    • Genome-wide RNAi screening identifies protein damage as a regulator of osmoprotective gene expression
    • Lamitina T, Huang CG, Strange K. Genome-wide RNAi screening identifies protein damage as a regulator of osmoprotective gene expression. Proc Natl Acad Sci USA 2006; 103:12173-12178.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12173-12178
    • Lamitina, T.1    Huang, C.G.2    Strange, K.3
  • 12
    • 33751351093 scopus 로고    scopus 로고
    • Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans
    • Wheeler JM, Thomas JH. Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans. Genetics 2006; 174:1327-1336.
    • (2006) Genetics , vol.174 , pp. 1327-1336
    • Wheeler, J.M.1    Thomas, J.H.2
  • 13
    • 77955767442 scopus 로고    scopus 로고
    • Systemic osmotic signaling pathways function upstream of WNK and GCK-VI kinases to regulate hypertonic stress resistance in C. elegans
    • Choe KP, Strange K. Systemic osmotic signaling pathways function upstream of WNK and GCK-VI kinases to regulate hypertonic stress resistance in C. elegans. FASEB J 2008; 22:933-939.
    • (2008) FASEB J , vol.22 , pp. 933-939
    • Choe, K.P.1    Strange, K.2
  • 14
    • 60849119836 scopus 로고    scopus 로고
    • Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase
    • Tong A, Lynn G, Ngo V, Wong D, Moseley SL, Ewbank JJ, et al. Negative regulation of Caenorhabditis elegans epidermal damage responses by death-associated protein kinase. Proc Natl Acad Sci USA 2009; 106:1457-1461.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1457-1461
    • Tong, A.1    Lynn, G.2    Ngo, V.3    Wong, D.4    Moseley, S.L.5    Ewbank, J.J.6
  • 15
    • 60749100012 scopus 로고    scopus 로고
    • Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGFbeta signaling pathway in Caenorhabditis elegans epidermis
    • Zugasti O, Ewbank JJ. Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGFbeta signaling pathway in Caenorhabditis elegans epidermis. Nature immunology 2009; 10:249-256.
    • (2009) Nature Immunology , vol.10 , pp. 249-256
    • Zugasti, O.1    Ewbank, J.J.2
  • 16
    • 2942696323 scopus 로고    scopus 로고
    • Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity
    • Rappleye CA, Tagawa A, Le Bot N, Ahringer J, Aroian RV. Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. BMC Dev Biol 2003; 3:8.
    • (2003) BMC Dev Biol , vol.3 , pp. 8
    • Rappleye, C.A.1    Tagawa, A.2    Le, B.N.3    Ahringer, J.4    Aroian, R.V.5
  • 17
    • 19344363119 scopus 로고    scopus 로고
    • Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development
    • Kniazeva M, Crawford QT, Seiber M, Wang CY, Han M. Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development. PLoS Biol 2004; 2:257.
    • (2004) PLoS Biol , vol.2 , pp. 257
    • Kniazeva, M.1    Crawford, Q.T.2    Seiber, M.3    Wang, C.Y.4    Han, M.5
  • 18
    • 48149109399 scopus 로고    scopus 로고
    • Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding
    • Greer ER, Perez CL, Van Gilst MR, Lee BH, Ashrafi K. Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metab 2008; 8:118-131.
    • (2008) Cell Metab , vol.8 , pp. 118-131
    • Greer, E.R.1    Perez, C.L.2    van Gilst, M.R.3    Lee, B.H.4    Ashrafi, K.5
  • 19
    • 0037274642 scopus 로고    scopus 로고
    • Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans
    • Kniazeva M, Sieber M, McCauley S, Zhang K, Watts JL, Han M. Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans. Genetics 2003; 163:159-169.
    • (2003) Genetics , vol.163 , pp. 159-169
    • Kniazeva, M.1    Sieber, M.2    McCauley, S.3    Zhang, K.4    Watts, J.L.5    Han, M.6
  • 20
    • 0032871502 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
    • Ntambi JM. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 1999; 40:1549-1558.
    • (1999) J Lipid Res , vol.40 , pp. 1549-1558
    • Ntambi, J.M.1
  • 21
    • 0034720457 scopus 로고    scopus 로고
    • A palmitoyl-CoA-specific delta9 fatty acid desaturase from Caenorhabditis elegans
    • Watts JL, Browse J. A palmitoyl-CoA-specific delta9 fatty acid desaturase from Caenorhabditis elegans. Biochem Biophys Res Commun 2000; 272:263-269.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 263-269
    • Watts, J.L.1    Browse, J.2
  • 22
    • 34250759430 scopus 로고    scopus 로고
    • Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans
    • Brock TJ, Browse J, Watts JL. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Genetics 2007; 176:865-875.
    • (2007) Genetics , vol.176 , pp. 865-875
    • Brock, T.J.1    Browse, J.2    Watts, J.L.3
  • 23
    • 48749115206 scopus 로고    scopus 로고
    • Elongation and desaturation of fatty acids are critical in growth, lipid metabolism and ontogeny of Caenorhabditis elegans
    • Horikawa M, Nomura T, Hashimoto T, Sakamoto K. Elongation and desaturation of fatty acids are critical in growth, lipid metabolism and ontogeny of Caenorhabditis elegans. J Biochem 2008; 144:149-158.
    • (2008) J Biochem , vol.144 , pp. 149-158
    • Horikawa, M.1    Nomura, T.2    Hashimoto, T.3    Sakamoto, K.4
  • 24
    • 34548761512 scopus 로고    scopus 로고
    • Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans
    • Choe KP, Strange K. Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans. Am J Physiol Cell Physiol 2007; 293:915-927.
    • (2007) Am J Physiol Cell Physiol , vol.293 , pp. 915-927
    • Choe, K.P.1    Strange, K.2
  • 25
    • 57149085057 scopus 로고    scopus 로고
    • Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity
    • Nandakumar M, Tan MW. Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. PLoS Genet 2008; 4:1000273.
    • (2008) PLoS Genet , vol.4 , pp. 1000273
    • Nandakumar, M.1    Tan, M.W.2
  • 26
    • 34250306819 scopus 로고    scopus 로고
    • Chemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals
    • Serrano M, Robatzek S, Torres M, Kombrink E, Somssich IE, Robinson M, et al. Chemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals. J Biol Chem 2007; 282:6803-6811.
    • (2007) J Biol Chem , vol.282 , pp. 6803-6811
    • Serrano, M.1    Robatzek, S.2    Torres, M.3    Kombrink, E.4    Somssich, I.E.5    Robinson, M.6
  • 27
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974; 77:71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 28
    • 85011938352 scopus 로고    scopus 로고
    • Introduction and Two-point Mapping
    • The C. elegans Research Community, ed. Chapter 4-SNPs
    • Fay D, Bender A. Chapter 4-SNPs: Introduction and two-point mapping. In: The C. elegans Research Community, ed. WormBook: WormBook.
    • Worm Book: Worm Book
    • Fay, D.1    Bender, A.2
  • 29
    • 0036637641 scopus 로고    scopus 로고
    • Bogaert T. unc-53 controls longitudinal migration in C. elegans
    • Stringham E, Pujol N, Vandekerckhove J, Bogaert T. unc-53 controls longitudinal migration in C. elegans. Development 2002; 129:3367-3379.
    • (2002) Development , vol.129 , pp. 3367-3379
    • Stringham, E.1    Pujol, N.2    Vandekerckhove, J.3
  • 30
    • 0036214657 scopus 로고    scopus 로고
    • PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans
    • Hobert O. PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans. Biotechniques 2002; 32:728-730.
    • (2002) Biotechniques , vol.32 , pp. 728-730
    • Hobert, O.1
  • 31
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons L, Court DL, Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 2001; 263:103-112.
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 32
    • 2942624115 scopus 로고    scopus 로고
    • Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments
    • Solomon A, Bandhakavi S, Jabbar S, Shah R, Beitel GJ, Morimoto RI. Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments. Genetics 2004; 167:161-170.
    • (2004) Genetics , vol.167 , pp. 161-170
    • Solomon, A.1    Bandhakavi, S.2    Jabbar, S.3    Shah, R.4    Beitel, G.J.5    Morimoto, R.I.6
  • 33
    • 0026540832 scopus 로고
    • Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase
    • Miquel M, Browse J. Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase. J Biol Chem 1992; 267:1502-1509.
    • (1992) J Biol Chem , vol.267 , pp. 1502-1509
    • Miquel, M.1    Browse, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.