메뉴 건너뛰기




Volumn 52, Issue 2, 2010, Pages 488-496

Voxel-based analysis of Alzheimer's disease PET imaging using a triplet of radiotracers: PIB, FDDNP, and FDG

Author keywords

Alzheimer; Amyloid; Metabolism; Neuropathology; Positron emission tomography; Tau

Indexed keywords

2 [1 [6 [(2 FLUOROETHYL) (METHYL)AMINO] 2 NAPHTHYL]ETHYLIDENE]MALONONITRILE F 18; AMYLOID; FLUORODEOXYGLUCOSE F 18; PITTSBURGH COMPOUND B; TRACER; UNCLASSIFIED DRUG; 2-(1-(6-((2-FLUOROETHYL)(METHYL)AMINO)-2-NAPHTHYL)ETHYLIDENE)MALONONITRILE; 2-(4'-(METHYLAMINO)PHENYL)-6-HYDROXYBENZOTHIAZOLE; ANILINE DERIVATIVE; GLUCOSE; NITRILE; RADIOPHARMACEUTICAL AGENT; THIAZOLE DERIVATIVE;

EID: 77955707891     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2010.04.013     Document Type: Article
Times cited : (66)

References (68)
  • 2
    • 0035893245 scopus 로고    scopus 로고
    • Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease
    • Agdeppa E.D., Kepe V., Liu J., Flores-Torres S., Satyamurthy N., Petric A., Cole G.M., Small G.W., Huang S.C., Barrio J.R. Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J. Neurosci. 2001, 21:RC189.
    • (2001) J. Neurosci. , vol.21
    • Agdeppa, E.D.1    Kepe, V.2    Liu, J.3    Flores-Torres, S.4    Satyamurthy, N.5    Petric, A.6    Cole, G.M.7    Small, G.W.8    Huang, S.C.9    Barrio, J.R.10
  • 3
    • 0036235195 scopus 로고    scopus 로고
    • Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies
    • Alexander G.E., Chen K., Pietrini P., Rapoport S.I., Reiman E.M. Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies. Am. J. Psychiatry 2002, 159:738-745.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 738-745
    • Alexander, G.E.1    Chen, K.2    Pietrini, P.3    Rapoport, S.I.4    Reiman, E.M.5
  • 4
    • 0025717816 scopus 로고
    • The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
    • Arnold S.E., Hyman B.T., Flory J., Damasio A.R., Van Hoesen G.W. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb. Cortex 1991, 1:103-116.
    • (1991) Cereb. Cortex , vol.1 , pp. 103-116
    • Arnold, S.E.1    Hyman, B.T.2    Flory, J.3    Damasio, A.R.4    Van Hoesen, G.W.5
  • 5
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore C., Lee V.M., Trojanowski J.Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 2007, 8:663-672.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 8
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol. 1991, 82:239-259.
    • (1991) Acta Neuropathol. , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 9
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H., Alafuzoff I., Arzberger T., Kretzschmar H., Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol. 2006, 112:389-404.
    • (2006) Acta Neuropathol. , vol.112 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 11
    • 41949121294 scopus 로고    scopus 로고
    • The brain's default network: anatomy, function, and relevance to disease
    • Buckner R.L., Andrews-Hanna J.R., Schacter D.L. The brain's default network: anatomy, function, and relevance to disease. Ann. N. Y. Acad. Sci. 2008, 1124:1-38.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1124 , pp. 1-38
    • Buckner, R.L.1    Andrews-Hanna, J.R.2    Schacter, D.L.3
  • 17
    • 0016823810 scopus 로고
    • "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 1975, 12:189-198.
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 19
    • 0028025257 scopus 로고
    • Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease
    • Gearing M., Rebeck G.W., Hyman B.T., Tigges J., Mirra S.S. Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:9382-9386.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 9382-9386
    • Gearing, M.1    Rebeck, G.W.2    Hyman, B.T.3    Tigges, J.4    Mirra, S.S.5
  • 20
    • 0032191016 scopus 로고    scopus 로고
    • Selective vulnerability of neocortical association areas in Alzheimer's disease
    • Giannakopoulos P., Hof P.R., Bouras C. Selective vulnerability of neocortical association areas in Alzheimer's disease. Microsc. Res. Tech. 1998, 43:16-23.
    • (1998) Microsc. Res. Tech. , vol.43 , pp. 16-23
    • Giannakopoulos, P.1    Hof, P.R.2    Bouras, C.3
  • 22
    • 0038326624 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment
    • Guillozet A.L., Weintraub S., Mash D.C., Mesulam M.M. Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment. Arch. Neurol. 2003, 60:729-736.
    • (2003) Arch. Neurol. , vol.60 , pp. 729-736
    • Guillozet, A.L.1    Weintraub, S.2    Mash, D.C.3    Mesulam, M.M.4
  • 23
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J.A., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.A.1    Selkoe, D.J.2
  • 24
    • 0028956963 scopus 로고
    • FDG PET and differential diagnosis of dementia
    • Herholz K. FDG PET and differential diagnosis of dementia. Alzheimer Dis. Assoc. Disord. 1995, 9:6-16.
    • (1995) Alzheimer Dis. Assoc. Disord. , vol.9 , pp. 6-16
    • Herholz, K.1
  • 26
    • 33749606053 scopus 로고    scopus 로고
    • Visualizing pathology deposits in the living brain of patients with Alzheimer's disease
    • Kepe V., Huang S.C., Small G.W., Satyamurthy N., Barrio J.R. Visualizing pathology deposits in the living brain of patients with Alzheimer's disease. Methods Enzymol. 2006, 412:144-160.
    • (2006) Methods Enzymol. , vol.412 , pp. 144-160
    • Kepe, V.1    Huang, S.C.2    Small, G.W.3    Satyamurthy, N.4    Barrio, J.R.5
  • 27
    • 23444440165 scopus 로고    scopus 로고
    • Glucose metabolism in early onset versus late onset Alzheimer's disease: an SPM analysis of 120 patients
    • Kim E.J., Cho S.S., Jeong Y., Park K.C., Kang S.J., Kang E., Kim S.E., Lee K.H., Na D.L. Glucose metabolism in early onset versus late onset Alzheimer's disease: an SPM analysis of 120 patients. Brain 2005, 128:1790-1801.
    • (2005) Brain , vol.128 , pp. 1790-1801
    • Kim, E.J.1    Cho, S.S.2    Jeong, Y.3    Park, K.C.4    Kang, S.J.5    Kang, E.6    Kim, S.E.7    Lee, K.H.8    Na, D.L.9
  • 30
    • 34248579112 scopus 로고    scopus 로고
    • 2-(2-[2-Dimethylaminothiazol-5-yl]ethenyl)-6- (2-[fluoro]ethoxy)benzoxazole: a novel PET agent for in vivo detection of dense amyloid plaques in Alzheimer's disease patients
    • Kudo Y., Okamura N., Furumoto S., Tashiro M., Furukawa K., Maruyama M., Itoh M., Iwata R., Yanai K., Arai H. 2-(2-[2-Dimethylaminothiazol-5-yl]ethenyl)-6- (2-[fluoro]ethoxy)benzoxazole: a novel PET agent for in vivo detection of dense amyloid plaques in Alzheimer's disease patients. J. Nucl. Med. 2007, 48:553-561.
    • (2007) J. Nucl. Med. , vol.48 , pp. 553-561
    • Kudo, Y.1    Okamura, N.2    Furumoto, S.3    Tashiro, M.4    Furukawa, K.5    Maruyama, M.6    Itoh, M.7    Iwata, R.8    Yanai, K.9    Arai, H.10
  • 33
    • 0023222380 scopus 로고
    • Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices
    • Lewis D.A., Campbell M.J., Terry R.D., Morrison J.H. Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices. J. Neurosci. 1987, 7:1799-1808.
    • (1987) J. Neurosci. , vol.7 , pp. 1799-1808
    • Lewis, D.A.1    Campbell, M.J.2    Terry, R.D.3    Morrison, J.H.4
  • 36
    • 0038792263 scopus 로고    scopus 로고
    • Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents
    • Mathis C.A., Wang Y., Holt D.P., Huang G.F., Debnath M.L., Klunk W.E. Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J. Med. Chem. 2003, 46:2740-2754.
    • (2003) J. Med. Chem. , vol.46 , pp. 2740-2754
    • Mathis, C.A.1    Wang, Y.2    Holt, D.P.3    Huang, G.F.4    Debnath, M.L.5    Klunk, W.E.6
  • 37
    • 74949131981 scopus 로고    scopus 로고
    • The role of imaging in drug development
    • McCarthy T.J. The role of imaging in drug development. Q. J. Nucl. Med. Mol. Imaging 2009, 53:382-386.
    • (2009) Q. J. Nucl. Med. Mol. Imaging , vol.53 , pp. 382-386
    • McCarthy, T.J.1
  • 38
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 39
    • 0030874251 scopus 로고    scopus 로고
    • Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
    • Minoshima S., Giordani B., Berent S., Frey K.A., Foster N.L., Kuhl D.E. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann. Neurol. 1997, 42:85-94.
    • (1997) Ann. Neurol. , vol.42 , pp. 85-94
    • Minoshima, S.1    Giordani, B.2    Berent, S.3    Frey, K.A.4    Foster, N.L.5    Kuhl, D.E.6
  • 41
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR): current version and scoring rules
    • Morris J.C. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993, 43:2412-2414.
    • (1993) Neurology , vol.43 , pp. 2412-2414
    • Morris, J.C.1
  • 44
    • 34447326955 scopus 로고    scopus 로고
    • Amyloid imaging in Alzheimer's disease
    • Nordberg A. Amyloid imaging in Alzheimer's disease. Curr. Opin. Neurol. 2007, 20:398-402.
    • (2007) Curr. Opin. Neurol. , vol.20 , pp. 398-402
    • Nordberg, A.1
  • 45
    • 0024324825 scopus 로고
    • Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals
    • Padgett H.C., Schmidt D.G., Luxen A., Bida G.T., Satyamurthy N., Barrio J.R. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Int. J. Rad. Appl. Instrum. A 1989, 40:433-445.
    • (1989) Int. J. Rad. Appl. Instrum. A , vol.40 , pp. 433-445
    • Padgett, H.C.1    Schmidt, D.G.2    Luxen, A.3    Bida, G.T.4    Satyamurthy, N.5    Barrio, J.R.6
  • 48
    • 64349110759 scopus 로고    scopus 로고
    • Alzheimer's Disease: A Light at the End of the Tunnel?
    • Robichaud A.J., Rotella D.P. Alzheimer's Disease: A Light at the End of the Tunnel?. Drug Dev. Res. 2009, 70:57-59.
    • (2009) Drug Dev. Res. , vol.70 , pp. 57-59
    • Robichaud, A.J.1    Rotella, D.P.2
  • 49
    • 73349091534 scopus 로고    scopus 로고
    • A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
    • Salloway S., Sperling R., Gilman S., Fox N.C., Blennow K., et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 2009, 73:2061-2070.
    • (2009) Neurology , vol.73 , pp. 2061-2070
    • Salloway, S.1    Sperling, R.2    Gilman, S.3    Fox, N.C.4    Blennow, K.5
  • 50
    • 35348936103 scopus 로고    scopus 로고
    • Beyond amyloid: the next generation of Alzheimer's disease therapeutics
    • Seabrook G.R., Ray W.J., Shearman M., Hutton M. Beyond amyloid: the next generation of Alzheimer's disease therapeutics. Mol. Interv. 2007, 7:261-270.
    • (2007) Mol. Interv. , vol.7 , pp. 261-270
    • Seabrook, G.R.1    Ray, W.J.2    Shearman, M.3    Hutton, M.4
  • 52
    • 53049093702 scopus 로고    scopus 로고
    • Multitracer PET imaging of amyloid plaques and neurofibrillary tangles in Alzheimer's disease
    • Shin J., Lee S.Y., Kim S.H., Kim Y.B., Cho S.J. Multitracer PET imaging of amyloid plaques and neurofibrillary tangles in Alzheimer's disease. Neuroimage 2008, 43:236-244.
    • (2008) Neuroimage , vol.43 , pp. 236-244
    • Shin, J.1    Lee, S.Y.2    Kim, S.H.3    Kim, Y.B.4    Cho, S.J.5
  • 53
    • 71849097133 scopus 로고    scopus 로고
    • Phospholipase C b4 in the medial septum controls cholinergic theta oscillations and anxiety behaviors.
    • Shin J., Gireesh G., Kim S.W., Kim D.S., Lee S., Kim Y.S., Watanabe M., Shin H.S. Phospholipase C b4 in the medial septum controls cholinergic theta oscillations and anxiety behaviors. J. Neurosci. 2009, 29:15375-15385.
    • (2009) J. Neurosci. , vol.29 , pp. 15375-15385
    • Shin, J.1    Gireesh, G.2    Kim, S.W.3    Kim, D.S.4    Lee, S.5    Kim, Y.S.6    Watanabe, M.7    Shin, H.S.8
  • 54
    • 75149137436 scopus 로고    scopus 로고
    • 2-(1-{6-[(2-[Fluorine-18]fluoroethyl)(methyl) amino]-2-naphthyl}ethylidene)malononitrile (FDDNP) positron emission tomography patterns in nondemented populations
    • Shin J., Lee S.Y. 2-(1-{6-[(2-[Fluorine-18]fluoroethyl)(methyl) amino]-2-naphthyl}ethylidene)malononitrile (FDDNP) positron emission tomography patterns in nondemented populations. Am. J. Geriatr. Psychiatry 2010, 18:187.
    • (2010) Am. J. Geriatr. Psychiatry , vol.18 , pp. 187
    • Shin, J.1    Lee, S.Y.2
  • 55
    • 79953243454 scopus 로고    scopus 로고
    • Towards development of drugs targeting both amyloid and tau pathologies of Alzheimer's disease
    • in press
    • Shin, J., in press. Towards development of drugs targeting both amyloid and tau pathologies of Alzheimer's disease. Int. J. Geriatr. Psychiatry.
    • Int. J. Geriatr. Psychiatry.
    • Shin, J.1
  • 57
    • 56349119351 scopus 로고    scopus 로고
    • Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
    • Small S.A., Duff K. Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron 2008, 60:534-542.
    • (2008) Neuron , vol.60 , pp. 534-542
    • Small, S.A.1    Duff, K.2
  • 59
    • 33749455937 scopus 로고    scopus 로고
    • Seeing is believing: neuroimaging adds to our understanding of cerebral pathology
    • Small G.W., Kepe V., Barrio J.R. Seeing is believing: neuroimaging adds to our understanding of cerebral pathology. Curr. Opin. Psychiatry 2006, 19:564-569.
    • (2006) Curr. Opin. Psychiatry , vol.19 , pp. 564-569
    • Small, G.W.1    Kepe, V.2    Barrio, J.R.3
  • 61
    • 36849052336 scopus 로고    scopus 로고
    • Imaging as a tool in drug development
    • Strack T. Imaging as a tool in drug development. Drugs Today (Barc) 2007, 43:725-736.
    • (2007) Drugs Today (Barc) , vol.43 , pp. 725-736
    • Strack, T.1
  • 62
    • 0036736218 scopus 로고    scopus 로고
    • Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease
    • Suh Y.H., Checler F. Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacol. Rev. 2002, 54:469-525.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 469-525
    • Suh, Y.H.1    Checler, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.