Emission of diacetyl (2,3 butanedione) from natural butter, microwave popcorn butter flavor powder, paste, and liquid products

International Journal of Occupational and Environmental Health

Volumn 16, Issue 3, 2010, Pages 291-302

  Rigler, Mark W ^a   Longo, William E ^a  

^a Materials Analytical Services   (United States)

Author keywords

2,3 butanedione; Butter flavoring; Diacetyl; Emissions; Microwave popcorn; Scanning electron microscopy (SEM)

Indexed keywords

2,3 BUTANEDIONE; FLAVORING AGENT;

AIR POLLUTANT; ARTICLE; BUTTER; DUST; FOOD INDUSTRY; HUMAN; PARTICULATE MATTER;

AIR POLLUTANTS, OCCUPATIONAL; BUTTER; DIACETYL; DUST; FLAVORING AGENTS; FOOD-PROCESSING INDUSTRY; HUMANS; PARTICULATE MATTER;

EID: 77955669731     PISSN: 10773525     EISSN: None     Source Type: Journal    
DOI: 10.1179/oeh.2010.16.3.291     Document Type: Article

References (16)

1. Parmet AJ, Von Essen S. Rapidly progressive, fixed airway disease in popcorn workers: A new occupational pulmonary illness. J Occup Environ Med. 2002;44:216-221
2. Kanwal R. Bronciolitis obliterans in workers exposed to flavoring chemicals. Curr Opin.Pulmon Med. 2008;14:141-146.
3. Kanwal R, Kullman G, Fedan K, Kreiss K. Health hazard evaluation report. Report No. HETA 2000-0401-2991. Gilster-Mary Lee Corporation, Jasper, MO. Cincinnati,OH: National Institute of Occupational Safety and Health; 2006.
4. Kanwal R, Kullman G. Health hazard evaluation report. Report No. HETA2003-0112-2949. ConAgra Snack Foods, Marion, OH. Cincinnati,OH: National Institute of Occupational Safety and Health; 2004.
5. American Conference of Governmental Industrial Hygienists (ACGIH). 2006 TLV's and BEI's based on the documentation of the Threshold Limit Values for chemical substances and physical agents & biological exposure indices. Cincinnati, OH: ACGIH Worldwide; 2006.
6. Hubbs AF, Battelli LA, Goldsmith WT, et al. Necrosis of nasal and airway epithelium in rats inhaling vapors of artificial butter flavoring. Toxicol Appl Pharmacol. 2002;185:128-135
7. Integrated Laboratory Systems, Inc. Chemical Information Review Document for Artificial Butter Flavoring and Constituents Diacetyl [CAS No. 431-03-8] and Acetoin [CAS No. 513-86-90 Jan. 2007. Contract No. N01-ES-35515. Research Triangle Park, NC: US Department of Labor, Occupational Safety and Health Administration, National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services; 2007.
8. Shah, YC. Diacetyl; Method PV 2118 [Internet]. Salt Lake City, UT (US): US Department of Labor, Occupational Safety and Health Administration; 2003 Jan (Updated 2006 Sept). Available from: http://www.osha.gov/dts/sltc/methods/ partial/t-pv 2118/t-pv2118.html.
9. Hardwick WA. Interactive flavor influence of some materials in different food and beverages. In: Apt CM, ed. Flavor: Its chemical, behavioral, and commercial aspects. Proceedings of the Arthur D. Little, Inc. Flavor Symposium, 1977. Boulder, CO: Westview Press; 1978.
10. Moloney E, O'Sullivan S, Hogan T, Poulter LW, Burke CM. Airway dehydration: A therapeutic target in asthma? Chest. 2002;121;1806-1811
11. Martyny JW, Van Dyke MV, Arbuckle S, Towle M, Rose CS. Diacetyl exposures in the flavor manufacturing industry. J Occup. Environ Hyg. 2008; (5)11:679-688.
12. Boylstein R, Piacitelli C, Grote A, Kanwal R, Kullman G, Kreiss K. Diacetyl emissions and airborne dust from butter flavorings used in microwave popcorn production. J Occup Environ Hyg. 2006;3:530-535
13. Richards JR, Goshaw GD, Palm BL. Basic concepts of environmental science. Module 3: Characteristics of Particles-Aerodynamic Diameter. [Internet]. North Carolina: Air Pollution Training Institute, US Environmental Protection Agency; 2008. Available from: http://www.epa.gov/apti/bces/module3/ diameter/diameter. htm.
14. Patton JS. Mechanism and macromolecule absorption by the lungs. Adv Drug Delivery Rev. 1996; 19:3-36.
15. Hubbs AF, et al. Respiratory toxicologic pathology of inhaled diacetyl in Sprague-Dawley rats. Toxicol Pathol. 2008. (36)2:330-344.
16. Morgan DL, Flake GP, Kirby PJ, Palmer SM. Respiratory toxicity of diacetyl in C57BL/6 mice. Toxicol Sci. 2008 (103)1:169-180.