-
1
-
-
33751217731
-
Mechanosensitive channel gating transitions resolved by functional changes upon pore modiWcation
-
Bartlett JL, Li Y, Blount P (2006) Mechanosensitive channel gating transitions resolved by functional changes upon pore modiWcation. Biophys J 91(10):3684-3691
-
(2006)
Biophys J
, vol.91
, Issue.10
, pp. 3684-3691
-
-
Bartlett, J.L.1
Li, Y.2
Blount, P.3
-
3
-
-
0030999097
-
Molecular dynamics simulations of a Xuid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature
-
Berger O, Edholm O, Jahnig F (1997) Molecular dynamics simulations of a Xuid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys J 72(5):2002-2013
-
(1997)
Biophys J
, vol.72
, Issue.5
, pp. 2002-2013
-
-
Berger, O.1
Edholm, O.2
Jahnig, F.3
-
4
-
-
0035070279
-
The formation and dynamics of proton wires in channel environments
-
Brewer ML, Schmitt UW, Voth GA (2001) The formation and dynamics of proton wires in channel environments. Biophys J 80(4):1691-1702
-
(2001)
Biophys J
, vol.80
, Issue.4
, pp. 1691-1702
-
-
Brewer, M.L.1
Schmitt, U.W.2
Voth, G.A.3
-
5
-
-
36549041108
-
Proton transport behavior through the inXuenza A M2 channel: Insights from molecular simulation
-
Chen H, Wu Y, Voth GA (2007) Proton transport behavior through the inXuenza A M2 channel: insights from molecular simulation. Biophys J 93(10):3470-3479
-
(2007)
Biophys J
, vol.93
, Issue.10
, pp. 3470-3479
-
-
Chen, H.1
Wu, Y.2
Voth, G.A.3
-
6
-
-
33846823909
-
Particle mesh Ewald: an Nlog( N) method for Ewald sums in large systems
-
Darden T, York D, Pedersen L (1993) Particle mesh Ewald: an Nlog( N) method for Ewald sums in large systems. J Chem Phys 98:10089-10092
-
(1993)
J Chem Phys
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
7
-
-
20144372892
-
Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel
-
Edwards MD, Li Y, Kim S, Miller S, Bartlett W, Black S, Dennison S, Iscla I, Blount P, Bowie JU, Booth IR (2005) Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel. Nat Struct Mol Biol 12(2):113-119
-
(2005)
Nat Struct Mol Biol
, vol.12
, Issue.2
, pp. 113-119
-
-
Edwards, M.D.1
Li, Y.2
Kim, S.3
Miller, S.4
Bartlett, W.5
Black, S.6
Dennison, S.7
Iscla, I.8
Blount, P.9
Bowie, J.U.10
Booth, I.R.11
-
8
-
-
0018305077
-
The matrix protein gene determines amantadine-sensitivity of inXuenza viruses
-
Hay AJ, Kennedy NC, Skehel JJ, Appleyard G (1979) The matrix protein gene determines amantadine-sensitivity of inXuenza viruses. J Gen Virol 42(1):189-191
-
(1979)
J Gen Virol
, vol.42
, Issue.1
, pp. 189-191
-
-
Hay, A.J.1
Kennedy, N.C.2
Skehel, J.J.3
Appleyard, G.4
-
9
-
-
0022157043
-
The molecular basis of the speciWc anti-inXuenza action of amantadine
-
Hay AJ, Wolstenholme AJ, Skehel JJ, Smith MH (1985) The molecular basis of the speciWc anti-inXuenza action of amantadine. EMBO J 4(11):3021-3024
-
(1985)
EMBO J
, vol.4
, Issue.11
, pp. 3021-3024
-
-
Hay, A.J.1
Wolstenholme, A.J.2
Skehel, J.J.3
Smith, M.H.4
-
12
-
-
0001538909
-
Canonical dynamics-equilibrium phase-space distributions
-
Hoover WG (1985) Canonical dynamics-equilibrium phase-space distributions. Phys Rev A 31(1):1695-1697
-
(1985)
Phys Rev A
, vol.31
, Issue.1
, pp. 1695-1697
-
-
Hoover, W.G.1
-
13
-
-
33646494326
-
Histidines, heart of the hydrogen ion channel from inXuenza A virus: Toward an understanding of conductance and proton selectivity
-
Hu J, Fu R, Nishimura K, Zhang L, Zhou HX, Busath DD, Vijayvergiya V, Cross TA (2006) Histidines, heart of the hydrogen ion channel from inXuenza A virus: toward an understanding of conductance and proton selectivity. Proc Natl Acad Sci USA 103(18):6865-6870
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.18
, pp. 6865-6870
-
-
Hu, J.1
Fu, R.2
Nishimura, K.3
Zhang, L.4
Zhou, H.X.5
Busath, D.D.6
Vijayvergiya, V.7
Cross, T.A.8
-
15
-
-
0242322528
-
An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins
-
Im W, Feig M, Brooks CL III (2003) An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins. Biophys J 85(5):2900-2918
-
(2003)
Biophys J
, vol.85
, Issue.5
, pp. 2900-2918
-
-
Im, W.1
Feig, M.2
Brooks III, C.L.3
-
16
-
-
28844493428
-
+ channel: The gating mechanism of inXuenza A M2
-
+ channel: the gating mechanism of inXuenza A M2. Structure 13(12):1789-1798
-
(2005)
Structure
, vol.13
, Issue.12
, pp. 1789-1798
-
-
Kass, I.1
Arkin, I.T.2
-
17
-
-
18744363916
-
A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor
-
Law RJ, Henchman RH, McCammon JA (2005) A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor. Proc Natl Acad Sci USA 102(19):6813-6818
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.19
, pp. 6813-6818
-
-
Law, R.J.1
Henchman, R.H.2
McCammon, J.A.3
-
18
-
-
0042836535
-
Proton conduction through the M2 protein of the inXuenza A virus; a quantitative, mechanistic analysis of experimental data
-
Lear JD (2003) Proton conduction through the M2 protein of the inXuenza A virus; a quantitative, mechanistic analysis of experimental data. FEBS Lett 552(1):17-22
-
(2003)
FEBS Lett
, vol.552
, Issue.1
, pp. 17-22
-
-
Lear, J.D.1
-
19
-
-
0035789518
-
GROMACS 3.0: A package for molecular simulation and trajectory analysis
-
Lindahl E, Hess B, van der Spoel D (2001) GROMACS 3.0: a package for molecular simulation and trajectory analysis. J Mol Mod 7:306-317
-
(2001)
J Mol Mod
, vol.7
, pp. 306-317
-
-
Lindahl, E.1
Hess, B.2
Van Der Spoel, D.3
-
20
-
-
59649114004
-
Gating mechanism of the InXuenza A M2 channel revealed by 1 and 2D-IR spectroscopies
-
Manor J, Mukherjee P, Lin Y, Leonov H, Skinner JL, Zanni MT, Arkin IT (2009) Gating mechanism of the InXuenza A M2 channel revealed by 1 and 2D-IR spectroscopies. Structure 17:247-254
-
(2009)
Structure
, vol.17
, pp. 247-254
-
-
Manor, J.1
Mukherjee, P.2
Lin, Y.3
Leonov, H.4
Skinner, J.L.5
Zanni, M.T.6
Arkin, I.T.7
-
21
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A, Fujiyoshi Y, Unwin N (2003) Structure and gating mechanism of the acetylcholine receptor pore. Nature 423(6943):949-955
-
(2003)
Nature
, vol.423
, Issue.6943
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
22
-
-
0037027306
-
+ channel helical bundle combining precise orientational and distance restraints from solid state NMR
-
+ channel helical bundle combining precise orientational and distance restraints from solid state NMR. Biochemistry 41(44):13170-13177
-
(2002)
Biochemistry
, vol.41
, Issue.44
, pp. 13170-13177
-
-
Nishimura, K.1
Kim, S.2
Zhang, L.3
Cross, T.A.4
-
23
-
-
84943502952
-
A molecular dynamics method for simulations in the canonical ensemble
-
Nośe S (1984) A molecular dynamics method for simulations in the canonical ensemble. Mol Phys 52(2):255-268
-
(1984)
Mol Phys
, vol.52
, Issue.2
, pp. 255-268
-
-
Nośe, S.1
-
24
-
-
84926811618
-
Constant pressure molecular dynamics for molecular systems
-
Nośe S, Klein ML (1983) Constant pressure molecular dynamics for molecular systems. Mol Phys 50:1055-1076
-
(1983)
Mol Phys
, vol.50
, pp. 1055-1076
-
-
Nośe, S.1
Klein, M.L.2
-
25
-
-
0035918599
-
Protonation of histidine and histidine- tryptophan interaction in the activation of the M2 ion channel from inXuenza a virus
-
Okada A, Miura T, Takeuchi H (2001) Protonation of histidine and histidine- tryptophan interaction in the activation of the M2 ion channel from inXuenza a virus. Biochemistry 40(20):6053-6060
-
(2001)
Biochemistry
, vol.40
, Issue.20
, pp. 6053-6060
-
-
Okada, A.1
Miura, T.2
Takeuchi, H.3
-
26
-
-
0019707626
-
Polymorphic transitions in single crystals: A new molecular dynamics method
-
Parrinello M, Rahman A (1981) Polymorphic transitions in single crystals: a new molecular dynamics method. J Appl Phys 52:7182-7190
-
(1981)
J Appl Phys
, vol.52
, pp. 7182-7190
-
-
Parrinello, M.1
Rahman, A.2
-
27
-
-
0026612385
-
InXuenza virus M2 protein has ion channel activity
-
Pinto LH, Holsinger LJ, Lamb RA (1992) InXuenza virus M2 protein has ion channel activity. Cell 69(3):517-528
-
(1992)
Cell
, vol.69
, Issue.3
, pp. 517-528
-
-
Pinto, L.H.1
Holsinger, L.J.2
Lamb, R.A.3
-
28
-
-
0030973121
-
The active oligomeric state of the minimalistic inXuenza virus M2 ion channel is a tetramer
-
Sakaguchi T, Tu Q, Pinto LH, Lamb RA (1997) The active oligomeric state of the minimalistic inXuenza virus M2 ion channel is a tetramer. Proc Natl Acad Sci USA 94(10):5000-5005
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.10
, pp. 5000-5005
-
-
Sakaguchi, T.1
Tu, Q.2
Pinto, L.H.3
Lamb, R.A.4
-
30
-
-
0030803839
-
The inXuenza A virus M2 channel: A molecular modeling and simulation study
-
Sansom MS, Kerr ID, Smith GR, Son HS (1997) The inXuenza A virus M2 channel: a molecular modeling and simulation study. Virology 233(1):163-173
-
(1997)
Virology
, vol.233
, Issue.1
, pp. 163-173
-
-
Sansom, M.S.1
Kerr, I.D.2
Smith, G.R.3
Son, H.S.4
-
31
-
-
38749106195
-
Structure and mechanism of the M2 proton channel of inXuenza A virus
-
Schnell JR, Chou JJ (2008) Structure and mechanism of the M2 proton channel of inXuenza A virus. Nature 451(7178):591-595
-
(2008)
Nature
, vol.451
, Issue.7178
, pp. 591-595
-
-
Schnell, J.R.1
Chou, J.J.2
-
32
-
-
38749151911
-
Structural basis for the function and inhibition of an inXuenza virus proton channel
-
StouVer AL, Acharya R, Salom D, Levine AS, Di Costanzo L, Soto CS, Tereshko V, Nanda V, Stayrook S, DeGrado WF (2008) Structural basis for the function and inhibition of an inXuenza virus proton channel. Nature 451(7178):596-599
-
(2008)
Nature
, vol.451
, Issue.7178
, pp. 596-599
-
-
Stouver, A.L.1
Acharya, R.2
Salom, D.3
Levine, A.S.4
Di Costanzo, L.5
Soto, C.S.6
Tereshko, V.7
Nanda, V.8
Stayrook, S.9
DeGrado, W.F.10
-
33
-
-
0042335655
-
Roles of the histidine and tryptophan side chains in the M2 proton channel from inXuenza A virus
-
Takeuchi H, Okada A, Miura T (2003) Roles of the histidine and tryptophan side chains in the M2 proton channel from inXuenza A virus. FEBS Lett 552(1):35-38
-
(2003)
FEBS Lett
, vol.552
, Issue.1
, pp. 35-38
-
-
Takeuchi, H.1
Okada, A.2
Miura, T.3
-
34
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits
-
Unwin N, Miyazawa A, Li J, Fujiyoshi Y (2002) Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits. J Mol Biol 319(5):1165-1176
-
(2002)
J Mol Biol
, vol.319
, Issue.5
, pp. 1165-1176
-
-
Unwin, N.1
Miyazawa, A.2
Li, J.3
Fujiyoshi, Y.4
-
35
-
-
0028980598
-
Activation of the M2 ion channel of inXuenza virus: A role for the transmembrane domain histidine residue
-
Wang C, Lamb RA, Pinto LH (1995) Activation of the M2 ion channel of inXuenza virus: a role for the transmembrane domain histidine residue. Biophys J 69(4):1363-1371
-
(1995)
Biophys J
, vol.69
, Issue.4
, pp. 1363-1371
-
-
Wang, C.1
Lamb, R.A.2
Pinto, L.H.3
-
36
-
-
25844476272
-
A computational study of the closed and open states of the inXuenza a M2 proton channel
-
Wu Y, Voth GA (2005) A computational study of the closed and open states of the inXuenza a M2 proton channel. Biophys J 89(4):2402-2411
-
(2005)
Biophys J
, vol.89
, Issue.4
, pp. 2402-2411
-
-
Wu, Y.1
Voth, G.A.2
-
37
-
-
49149107480
-
A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine
-
Yi M, Cross TA, Zhou HX (2008) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. J Phys Chem B 112(27):7977-7979
-
(2008)
J Phys Chem B
, vol.112
, Issue.27
, pp. 7977-7979
-
-
Yi, M.1
Cross, T.A.2
Zhou, H.X.3
|