메뉴 건너뛰기




Volumn 225, Issue 1, 2010, Pages 133-139

Increased neuronal Rab5 immunoreactive endosomes do not colocalize with TDP-43 in motor neuron disease

Author keywords

Cathepsin; Endosome; Lysosome; Motor neuron disease; Rab5; TDP 43; Ubiquitin

Indexed keywords

CATHEPSIN B; CATHEPSIN D; CATHEPSIN F; CATHEPSIN L; PROTEIN P62; RAB PROTEIN; TAR DNA BINDING PROTEIN; UBIQUITIN; DNA BINDING PROTEIN; PROTEIN TDP-43;

EID: 77955661185     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.06.004     Document Type: Article
Times cited : (11)

References (39)
  • 6
    • 55949117482 scopus 로고    scopus 로고
    • Cathepsins: key modulators of cell death and inflammatory responses
    • Conus S., Simon H.U. Cathepsins: key modulators of cell death and inflammatory responses. Biochem. Pharmacol. 2008, 76:1374-1382.
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 1374-1382
    • Conus, S.1    Simon, H.U.2
  • 13
    • 67749133873 scopus 로고    scopus 로고
    • TDP-43 is intrinsically aggregation-prone and ALS-linked mutations accelerate aggregation and increase toxicity
    • Johnson B.S., Snead D., Lee J.J., McCaffery J.M., Shorter J., Gitler A.D. TDP-43 is intrinsically aggregation-prone and ALS-linked mutations accelerate aggregation and increase toxicity. J. Biol. Chem. 2009, 284:20329-20339.
    • (2009) J. Biol. Chem. , vol.284 , pp. 20329-20339
    • Johnson, B.S.1    Snead, D.2    Lee, J.J.3    McCaffery, J.M.4    Shorter, J.5    Gitler, A.D.6
  • 14
    • 36949019768 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences
    • Kato S. Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol. 2008, 115:97-114.
    • (2008) Acta Neuropathol. , vol.115 , pp. 97-114
    • Kato, S.1
  • 15
    • 0038388993 scopus 로고    scopus 로고
    • Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis
    • Kikuchi H., Yamada T., Furuya H., Doh-ura K., Ohyagi Y., Iwaki T., Kira J. Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis. Acta Neuropathol. 2003, 105:462-468.
    • (2003) Acta Neuropathol. , vol.105 , pp. 462-468
    • Kikuchi, H.1    Yamada, T.2    Furuya, H.3    Doh-ura, K.4    Ohyagi, Y.5    Iwaki, T.6    Kira, J.7
  • 18
    • 34447531775 scopus 로고    scopus 로고
    • The Rab5 activator ALS2/alsin acts as a novel Rac1 effector through Rac1-activated endocytosis
    • Kunita R., Otomo A., Mizumura H., Suzuki-Utsunomiya K., Hadano S., Ikeda J.E. The Rab5 activator ALS2/alsin acts as a novel Rac1 effector through Rac1-activated endocytosis. J. Biol. Chem. 2007, 282:16599-16611.
    • (2007) J. Biol. Chem. , vol.282 , pp. 16599-16611
    • Kunita, R.1    Otomo, A.2    Mizumura, H.3    Suzuki-Utsunomiya, K.4    Hadano, S.5    Ikeda, J.E.6
  • 19
    • 47949093588 scopus 로고    scopus 로고
    • Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases
    • Lin W.L., Dickson D.W. Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. Acta Neuropathol. 2008, 116:205-213.
    • (2008) Acta Neuropathol. , vol.116 , pp. 205-213
    • Lin, W.L.1    Dickson, D.W.2
  • 21
    • 0024998817 scopus 로고
    • Efficient estimation of cell volume and number using the nucleator and the disector
    • Moller A., Strange P., Gundersen H.J. Efficient estimation of cell volume and number using the nucleator and the disector. J. Microsc. 1990, 159:61-71.
    • (1990) J. Microsc. , vol.159 , pp. 61-71
    • Moller, A.1    Strange, P.2    Gundersen, H.J.3
  • 22
    • 47949099336 scopus 로고    scopus 로고
    • Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia
    • Mori F., Tanji K., Zhang H.X., Nishihira Y., Tan C.F., Takahashi H., Wakabayashi K. Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008, 116:193-203.
    • (2008) Acta Neuropathol. , vol.116 , pp. 193-203
    • Mori, F.1    Tanji, K.2    Zhang, H.X.3    Nishihira, Y.4    Tan, C.F.5    Takahashi, H.6    Wakabayashi, K.7
  • 24
    • 0028806557 scopus 로고
    • The endosomal-lysosomal system of neurons: new roles
    • Nixon R.A., Cataldo A.M. The endosomal-lysosomal system of neurons: new roles. Trends Neurosci. 1995, 18:489-496.
    • (1995) Trends Neurosci. , vol.18 , pp. 489-496
    • Nixon, R.A.1    Cataldo, A.M.2
  • 25
    • 48249103491 scopus 로고    scopus 로고
    • Neurodegenerative lysosomal disorders: a continuum from development to late age
    • Nixon R.A., Yang D.S., Lee J.H. Neurodegenerative lysosomal disorders: a continuum from development to late age. Autophagy 2008, 4:590-599.
    • (2008) Autophagy , vol.4 , pp. 590-599
    • Nixon, R.A.1    Yang, D.S.2    Lee, J.H.3
  • 26
    • 58149498300 scopus 로고    scopus 로고
    • Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells
    • Nonaka T., Arai T., Buratti E., Baralle F.E., Akiyama H., Hasegawa M. Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells. FEBS Lett. 2009, 583:394-400.
    • (2009) FEBS Lett. , vol.583 , pp. 394-400
    • Nonaka, T.1    Arai, T.2    Buratti, E.3    Baralle, F.E.4    Akiyama, H.5    Hasegawa, M.6
  • 27
    • 41549114279 scopus 로고    scopus 로고
    • The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease
    • Pan T., Kondo S., Le W., Jankovic J. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain 2008, 131:1969-1978.
    • (2008) Brain , vol.131 , pp. 1969-1978
    • Pan, T.1    Kondo, S.2    Le, W.3    Jankovic, J.4
  • 30
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • Rink J., Ghigo E., Kalaidzidis Y., Zerial M. Rab conversion as a mechanism of progression from early to late endosomes. Cell 2005, 122:735-749.
    • (2005) Cell , vol.122 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 31
    • 37349034999 scopus 로고    scopus 로고
    • Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis
    • Sanelli T., Xiao S., Horne P., Bilbao J., Zinman L., Robertson J. Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis. J. Neuropathol. Exp. Neurol. 2007, 66:1147-1153.
    • (2007) J. Neuropathol. Exp. Neurol. , vol.66 , pp. 1147-1153
    • Sanelli, T.1    Xiao, S.2    Horne, P.3    Bilbao, J.4    Zinman, L.5    Robertson, J.6
  • 32
    • 0242321269 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases
    • Seachrist J.L., Ferguson S.S. Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases. Life Sci. 2003, 74:225-235.
    • (2003) Life Sci. , vol.74 , pp. 225-235
    • Seachrist, J.L.1    Ferguson, S.S.2
  • 34
    • 68049105101 scopus 로고    scopus 로고
    • Rab GTPases as coordinators of vesicle traffic
    • Stenmark H. Rab GTPases as coordinators of vesicle traffic. Nat. Rev. Mol. Cell Biol. 2009, 10:513-525.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 513-525
    • Stenmark, H.1
  • 35
    • 57049178339 scopus 로고    scopus 로고
    • Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy
    • Thorpe J.R., Tang H., Atherton J., Cairns N.J. Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy. J. Neural Transm. 2008, 115:1661-1671.
    • (2008) J. Neural Transm. , vol.115 , pp. 1661-1671
    • Thorpe, J.R.1    Tang, H.2    Atherton, J.3    Cairns, N.J.4
  • 36
    • 76549101965 scopus 로고    scopus 로고
    • Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43
    • Urushitani, M., Sato, T., Bamba, H., Hisa, Y., Tooyama, I., 2010. Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43. J. Neurosci. Res. 88, 784-797.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 784-797
    • Urushitani, M.1    Sato, T.2    Bamba, H.3    Hisa, Y.4    Tooyama, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.