Bisphosphonate protonation states, conformations, and dynamics on bone mineral probed by solid-state NMR without isotope enrichment

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 1, 2010, Pages 120-126

  Ironside, Matthew S ^a   Duer, Melinda J ^a   Reid, David G ^a   Byard, Stephen ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Department of Analytical Sciences ^*  (United Kingdom)

Author keywords

Biomaterials; Chemical shift anisotropy; Drug targeting; Molecular dynamics; Osteoporosis; REDOR

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CARBON; CRYSTALLIN; ISOTOPE; NERIDRONIC ACID; PAMIDRONIC ACID; PHOSPHORUS; TILUDRONIC ACID; ZOLEDRONIC ACID;

ANISOTROPY; ARTICLE; BONE MINERALIZATION; CARBON NUCLEAR MAGNETIC RESONANCE; CONFORMATION; DRUG STRUCTURE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; SENSITIVITY ANALYSIS; SOLID STATE;

EID: 77955660454     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.05.013     Document Type: Article

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