P53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2

Molecular Biology Reports

Volumn 37, Issue 6, 2010, Pages 2935-2940

  Xian, Lingling ^a,b   Zhao, Jing ^a   Wang, Jia ^a   Fang, Zhou ^a   Peng, Bo ^a   Wang, Wenzhang ^a   Ji, Xiaona ^a   Yu, Long ^a  

^a FUDAN UNIVERSITY   (China)

^b SHIHEZI UNIVERSITY   (China)

Author keywords

Degradation; HBx; HCC; Hepatitis B virus; MDM2; p53

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; PROTEASOME; PROTEIN MDM2; PROTEIN P53; PROTEIN BINDING; TRANSACTIVATOR PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOLECULAR MECHANICS; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; UBIQUITINATION; WILD TYPE; ANIMAL; GENETICS; METABOLISM; MOUSE; ONCOGENE; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; HUMANS; MICE; ONCOGENES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

HEPATITIS B VIRUS;

EID: 77955659895     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9855-1     Document Type: Article

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