Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells

Oncogene

Volumn 29, Issue 32, 2010, Pages 4576-4587

  Lee, S H ^a,b   Shen, G N ^b,c   Jung, Y S ^a   Lee, S J ^a   Chung, J Y ^a   Kim, H S ^a   Xu, Y ^a   Choi, Y ^b   Lee, J W ^a   Ha, N C ^a   Song, G Y ^c   Park, B J ^a  

^a Pusan National University   (South Korea)

^b Korea University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

anticancer drug; K Ras; p53; pancreatic cancer; Snail

Indexed keywords

ANTINEOPLASTIC AGENT; GN 25; GN 29; K RAS PROTEIN; PROTEIN P53; SMALL CHEMICAL INHIBITOR GN 25; SMALL CHEMICAL INHIBITOR GN 29; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SPECIFICITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TOXICITY TESTING; TUMOR XENOGRAFT; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHILD; DRUG EVALUATION, PRECLINICAL; FEMALE; GENES, RAS; HUMANS; MICE; MUTATION; NEOPLASMS; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

GASTROPODA;

EID: 77955659716     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.208     Document Type: Article

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