Expression and regulation in the brain of the chemokine CCL27 gene locus

Journal of Neuroimmunology

Volumn 225, Issue 1-2, 2010, Pages 82-90

  Gunsolly, Chad ^a   Nicholson, James D ^a   Listwak, Samuel J ^b   Ledee, Dolena ^c   Zelenka, Peggy ^c   Verthelyi, Daniela ^d   Chapoval, Svetlana ^e   Keegan, Achsah ^e   Tonelli, Leonardo H ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^e UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

Author keywords

Alternative splicing; CTACK; In situ hybridization; Neuroimmune; PESKY; RT PCR

Indexed keywords

CUTANEOUS T CELL ATTRACTING CHEMOKINE; NEUTRALIZING ANTIBODY;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; GENETIC VARIABILITY; IMMUNOREACTIVITY; INFLAMMATION; LIMBIC CORTEX; LYMPHOCYTE FUNCTION; MALE; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OLFACTORY BULB; PRIORITY JOURNAL; RNA SPLICING; T LYMPHOCYTE;

ALBUMINS; ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD3; AUTORADIOGRAPHY; BRAIN; CELL COUNT; CHEMOKINE CCL27; GENE EXPRESSION REGULATION; HYPERSENSITIVITY; MALE; MICE; MICE, INBRED BALB C; NEURONS; PROTEIN ISOFORMS; RNA, MESSENGER;

EID: 77955657856     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.04.019     Document Type: Article

References (45)

1. Aloisi F., Serafini B., Adorini L. Glia-T cell dialogue. J. Neuroimmunol. 2000, 107:111-117.
2. Aloisi F., Columba-Cabezas S., Franciotta D., Rosicarelli B., Magliozzi R., Reynolds R., Ambrosini E., Coccia E., Salvetti M., Serafini B. Lymphoid chemokines in chronic neuroinflammation. J. Neuroimmunol. 2008, 198:106-112.
3. Baird J.W., Nibbs R.J., Komai-Koma M., Connolly J.A., Ottersbach K., Clark-Lewis I., Liew F.Y., Graham G.J. ESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoforms. J. Biol. Chem. 1999, 274:33496-33503.
4. Brochard V., Combadiere B., Prigent A., Laouar Y., Perrin A., Beray-Berthat V., Bonduelle O., Alvarez-Fischer D., Callebert J., Launay J.M., Duyckaerts C., Flavell R.A., Hirsch E.C., Hunot S. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J. Clin. Invest. 2009, 119:182-192.
5. Cartier L., Hartley O., Dubois-Dauphin M., Krause K.H. Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res. Brain Res. Rev. 2005, 48:16-42.
6. Chen L., Lin S.X., Agha-Majzoub R., Overbergh L., Mathieu C., Chan L.S. CCL27 is a critical factor for the development of atopic dermatitis in the keratin-14 IL-4 transgenic mouse model. Int. Immunol. 2006, 18:1233-1242.
7. Cohen H., Ziv Y., Cardon M., Kaplan Z., Matar M.A., Gidron Y., Schwartz M., Kipnis J. Maladaptation to mental stress mitigated by the adaptive immune system via depletion of naturally occurring regulatory CD4+ CD25+ cells. J. Neurobiol. 2006, 66:552-563.
8. Danielyan L., Schäfer R., von Ameln-Mayerhofer A., Buadze M., Geisler J., Klopfer T., Burkhardt U., Proksch B., Verleysdonk S., Ayturan M., Buniatian G.H., Gleiter C.H., Frey W.H. Intranasal delivery of cells to the brain. Eur. J. Cell Biol. 2009, 88(6):315-324.
9. Dhabhar F.S., Saul A.N., Daugherty C., Holmes T.H., Bouley D.M., Oberyszyn T.M. Short-term stress enhances cellular immunity and increases early resistance to squamous cell carcinoma. Brain Behav. Immun. 2010, 24(1):127-137.
10. Dorf M.E., Berman M.A., Tanabe S., Heesen M., Luo Y. Astrocytes express functional chemokine receptors. J. Neuroimmunol. 2000, 111:109-121.
11. Gao J.Q., Tsuda Y., Katayama K., Nakayama T., Hatanaka Y., Tani Y., Mizuguchi H., Hayakawa T., Yoshie O., Tsutsumi Y., Mayumi T., Nakagawa S. Antitumor effect by interleukin-11 receptor alpha-locus chemokine/CCL27, introduced into tumor cells through a recombinant adenovirus vector. Cancer Res. 2003, 63:4420-4425.
12. Gao J.Q., Tsuda Y., Han M., Xu D.H., Kanagawa N., Hatanaka Y., Tani Y., Mizuguchi H., Tsutsumi Y., Mayumi T., Okada N., Nakagawa S. NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy. Cancer Immunol. Immunother. 2009, 58:291-299.
13. Gortz A., Nibbs R.J., McLean P., Jarmin D., Lambie W., Baird J.W., Graham G.J. The chemokine ESkine/CCL27 displays novel modes of intracrine and paracrine function. J. Immunol. 2002, 169:1387-1394.
14. Homey B., Wang W., Soto H., Buchanan M.E., Wiesenborn A., Catron D., Muller A., McClanahan T.K., Dieu-Nosjean M.C., Orozco R., Ruzicka T., Lehmann P., Oldham E., Zlotnik A. Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J. Immunol. 2000, 164:3465-3470.
15. Homey B., Alenius H., Muller A., Soto H., Bowman E.P., Yuan W., McEvoy L., Lauerma A.I., Assmann T., Bunemann E., Lehto M., Wolff H., Yen D., Marxhausen H., To W., Sedgwick J., Ruzicka T., Lehmann P., Zlotnik A. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 2002, 8:157-165.
16. Hromas R., Broxmeyer H.E., Kim C., Christopherson K., Hou Y.H. Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension. Biochem. Biophys. Res. Commun. 1999, 258:737-740.
17. Huang V., Lonsdorf A.S., Fang L., Kakinuma T., Lee V.C., Cha E., Zhang H., Nagao K., Zaleska M., Olszewski W.L., Hwang S.T. Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells. J. Immunol. 2008, 180:6462-6466.
18. Ishikawa-Mochizuki I., Kitaura M., Baba M., Nakayama T., Izawa D., Imai T., Yamada H., Hieshima K., Suzuki R., Nomiyama H., Yoshie O. Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of a CC chemokine encoded by molluscum contagiosum virus. FEBS Lett. 1999, 460:544-548.
19. Jarmin D.I., Rits M., Bota D., Gerard N.P., Graham G.J., Clark-Lewis I., Gerard C. Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. J. Immunol. 2000, 164:3460-3464.
20. Kagami S., Saeki H., Tsunemi Y., Nakamura K., Kuwano Y., Komine M., Nakayama T., Yoshie O., Tamaki K. CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli. Eur. J. Immunol. 2008, 38:647-657.
21. Kelly-Welch A.E., Melo M.E., Smith E., Ford A.Q., Haudenschild C., Noben-Trauth N., Keegan A.D. Complex role of the IL-4 receptor alpha in a murine model of airway inflammation: expression of the IL-4 receptor alpha on nonlymphoid cells of bone marrow origin contributes to severity of inflammation. J. Immunol. 2004, 172:4545-4555.
22. KleinJan A., Willart M., van Rijt L.S., Braunstahl G.J., Leman K., Jung S., Hoogsteden H.C., Lambrecht B.N. An essential role for dendritic cells in human and experimental allergic rhinitis. J. Allergy Clin. Immunol. 2006, 118:1117-1125.
23. Kunkel E.J., Butcher E.C. Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002, 16:1-4.
24. Ledee D.R., Chen J., Tonelli L.H., Takase H., Gery I., Zelenka P.S. Differential expression of splice variants of chemokine CCL27 mRNA in lens, cornea, and retina of the normal mouse eye. Mol. Vis. 2004, 10:663-667.
25. Lewitus G.M., Schwartz M. Behavioral immunization: immunity to self-antigens contributes to psychological stress resilience. Mol. Psychiatry 2009, 14:532-536.
26. Lewitus G.M., Cohen H., Schwartz M. Reducing post-traumatic anxiety by immunization. Brain Behav. Immun. 2008, 22:1108-1114.
27. Lewitus G.M., Wilf-Yarkoni A., Ziv Y., Shabat-Simon M., Gersner R., Zangen A., Schwartz M. Vaccination as a novel approach for treating depressive behavior. Biol. Psychiatry 2009, 65:283-288.
28. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
29. Meucci O., Fatatis A., Simen A.A., Bushell T.J., Gray P.W., Miller R.J. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:14500-14505.
30. Morales J., Homey B., Vicari A.P., Hudak S., Oldham E., Hedrick J., Orozco R., Copeland N.G., Jenkins N.A., McEvoy L.M., Zlotnik A. CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:14470-14475.
31. Nibbs R.J., Graham G.J. CCL27/PESKY: a novel paradigm for chemokine function. Expert Opin. Biol. Ther. 2003, 3:15-22.
32. O'Connor R.A., Prendergast C.T., Sabatos C.A., Lau C.W., Leech M.D., Wraith D.C., Anderton S.M. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J. Immunol. 2008, 181:3750-3754.
33. Pedras-Vasconcelos J.A., Goucher D., Puig M., Tonelli L.H., Wang V., Ito S., Verthelyi D. CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus. J. Immunol. 2006, 176:4940-4949.
34. Pivarcsi A., Muller A., Hippe A., Rieker J., van Lierop A., Steinhoff M., Seeliger S., Kubitza R., Pippirs U., Meller S., Gerber P.A., Liersch R., Buenemann E., Sonkoly E., Wiesner U., Hoffmann T.K., Schneider L., Piekorz R., Enderlein E., Reifenberger J., Rohr U.P., Haas R., Boukamp P., Haase I., Nurnberg B., Ruzicka T., Zlotnik A., Homey B. Tumor immune escape by the loss of homeostatic chemokine expression. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:19055-19060.
35. Prendergast C.T., Anderton S.M. Immune cell entry to central nervous system - current understanding and prospective therapeutic targets. Endocr. Metab. Immune Disord. Drug Targets 2009, 9(4):315-327. (PMID: 20028334).
36. Reiss Y., Proudfoot A.E., Power C.A., Campbell J.J., Butcher E.C. CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J. Exp. Med. 2001, 194:1541-1547.
37. Schwartz M., Ziv Y. Immunity to self and self-maintenance: a unified theory of brain pathologies. Trends Immunol. 2008, 29(5):211-219. (PMID: 18328784).
38. Seksenyan A., Ron-Harel N., Azoulay D., Cahalon L., Cardon M., Rogeri P., Ko M.K., Weil M., Bulvik S., Rechavi G., Amariglio N., Konen E., Koronyo-Hamaoui M., Somech R., Schwartz M. Thymic involution in amyotrophic lateral sclerosis. J. Cell. Mol. Med. 2009.
39. Tonelli L.H., Maeda S., Rapp K.L., Sternberg E.M. Differential induction of interleukin-I beta mRNA in the brain parenchyma of Lewis and Fischer rats after peripheral injection of lipopolysaccharides. J. Neuroimmunol. 2003, 140:126-136.
40. Tonelli L.H., Holmes A., Postolache T.T. Intranasal immune challenge induces sex-dependent depressive-like behavior and cytokine expression in the brain. Neuropsychopharmacology 2008, 33:1038-1048.
41. Tonelli L.H., Katz M., Kovacsics C.E., Gould T.D., Joppy B., Hoshino A., Hoffman G., Komarow H., Postolache T.T. Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents. Brain Behav. Immun. 2009, 23:784-793.
42. Vestergaard C., Deleuran M., Gesser B., Larsen C.G. Thymus- and activation-regulated chemokine (TARC/CCL17) induces a Th2-dominated inflammatory reaction on intradermal injection in mice. Exp. Dermatol. 2004, 13:265-271.
43. Vestergaard C., Johansen C., Christensen U., Just H., Hohwy T., Deleuran M. TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp. Dermatol. 2004, 13:551-557.
44. Wilusz J.E., Sunwoo H., Spector D.L. Long noncoding RNAs: functional surprises from the RNA world. Genes Dev. 2009, 23:1494-1504.
45. Ziv Y., Ron N., Butovsky O., Landa G., Sudai E., Greenberg N., Cohen H., Kipnis J., Schwartz M. Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat. Neurosci. 2006, 9:268-275.