Asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation

Tetrahedron

Volumn 66, Issue 33, 2010, Pages 6565-6568

  Rueping, Magnus ^a   Stoeckel, Mirjam ^b   Sugiono, Erli ^a   Theissmann, Thomas ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Asymmetric reduction; Br nsted acid; Flumequine; Levofloxacine; Organocatalysis

Indexed keywords

6 FLUORO 2 METHYLTETRAHYDROQUINOLINE; 7,8 DIFLUORO 3 METHYL BENZOXAZINE; BRONSTED ACID; FLUMEQUINE; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CATALYST; DRUG SYNOVIAL FLUID LEVEL; ENANTIOSELECTIVITY; ENVIRONMENTAL TEMPERATURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; PRIORITY JOURNAL;

EID: 77955656206     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.04.091     Document Type: Article

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