Livin abrogates apoptosis of SPC-A1 cell by regulating JNKI signaling pathway

Molecular Biology Reports

Volumn 37, Issue 5, 2010, Pages 2241-2247

  Chen, Yu Sheng ^a   Li, Hong Ru ^a   Lin, Ming ^a   Chen, Gang ^a   Xie, Bao Song ^a   Xu, Neng Luan ^a   Lin, Li Fang ^b  

^a FUJIAN PROVINCIAL HOSPITAL   (China)

^b Fujian Provincial Key Laboratory of Angiocardiopathy   (China)

Author keywords

Apoptosis; Human livin protein; JNK1 kinase; RNA interference; shRNA

Indexed keywords

CASPASE 3; LIVIN; MESSENGER RNA; STRESS ACTIVATED PROTEIN KINASE 1;

APOPTOSIS; ARTICLE; CELL STRAIN; CELL STRAIN SPC A1; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CELL LINE, TUMOR; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LENTIVIRUS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 8; NEOPLASM PROTEINS; PHOSPHORYLATION; RNA, SMALL INTERFERING;

EID: 77955654602     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9711-3     Document Type: Article

References (31)

1. EJ Dean M Ranson F Blackhall SV Holt C Dive 2007 Novel therapeutic targets in lung cancer: inhibitor of apoptosis proteins from laboratory to clinic Cancer Treat Rev 33 203 212 10.1016/j.ctrv.2006.11.002 1:CAS:528:DC%2BD2sXitl2jtLY%3D 17210228 (Pubitemid 46323397)
2. AM Hunter EC LaCasse RG Korneluk 2007 The inhibitors of apoptosis (IAPs) as cancer targets Apoptosis 2 1543 1568 10.1007/s10495-007-0087-3 (Pubitemid 47106887)
3. AD Schimmer S Dalili RA Batey SJ Riedl 2006 Targeting XIAP for the treatment of malignancy Cell Death Differ 3 179 188 10.1038/sj.cdd.4401826 (Pubitemid 43102202)
4. M Pennati M Folini N Zaffaroni 2008 Targeting survivin in cancer therapy Expert Opin Ther Targets 2 463 476 10.1517/14728222.12.4.463 (Pubitemid 351551639)
5. Y Ashhab A Alian A Polliack A Panet D Ben Yehuda 2001 Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern FEBS Lett 495 56 60 10.1016/S0014-5793(01)02366-3 1:CAS:528:DC%2BD3MXivFegsrw%3D 11322947 (Pubitemid 32367973)
6. J Choi YK Hwang KW Sung SH Lee KH Yoo HL Jung HH Koo HJ Kim HJ Kang HY Shin HS Ahn 2007 Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia Blood 109 471 477 10.1182/blood-2006-07-032557 1:CAS:528: DC%2BD2sXivVykuro%3D 16990595 (Pubitemid 46105940)
7. H Hariu Y Hirohashi T Torigoe H Asanuma M Hariu Y Tamura K Aketa C Nabeta K Nakanishi K Kamiguchi Y Mano H Kitamura J Kobayashi T Tsukahara N Shijubo N Sato 2005 Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer Clin Cancer Res 11 1000 1009 1:CAS:528:DC%2BD2MXht1ynsb8%3D 15709165
8. JH Li WJ He YJ He 2007 Expression and clinical significance of Survivin and Livin in DukesoB colorectal cancer Ai Zheng 26 547 551 17672950
9. T Song BF Hong JP Gao L Zhang W Cai 2008 Expression of apoptosis inhibitor gene Livin in prostate cancer and its clinical implication Zhonghua Nan Ke Xue 14 30 33 1:CAS:528:DC%2BD1MXhvVCjs70%3D 18297808
10. T Nedelcu B Kubista A Koller I Sulzbacher I Mosberger F Arrich K Trieb R Kotz CD Toma 2008 Livin and Bcl-2 expression in high-grade osteosarcoma J Cancer Res Clin Oncol 134 237 244 10.1007/s00432-007-0276-z 1:CAS:528: DC%2BD2sXhsVSls7fJ 17632732 (Pubitemid 350234069)
11. P Liu TS Wang SH You HM Ge 2007 Expression of livin in gastric dancer and effect of silencing of the livin gene on apoptosis in gastric cancer cells Zhonghua Zhong Liu Za Zhi 29 570 574 1:CAS:528:DC%2BD1cXisFChsbY%3D 18210873
12. C Kempkensteffen S Hinz H Krause T Jager J Köllermann S Weikert F Christoph M Schostak K Miller M Schrader 2008 Expression of splicing variants of the inhibitor of apoptosis Livin in testicular germ cell tumors Tumour Biol 29 76 82 10.1159/000135687 1:CAS:528:DC%2BD1cXosl2msbk%3D 18515985
13. Liu HB, Kong CZ, Zeng Y, Liu XK, Bi JB, Jiang YJ, Han S (2008) Livin may serve as a marker for prognosis of bladder cancer relapse and a target of bladder cancer treatment. Urol Oncol [Epub ahead of print]
14. H Chang AD Schimmer 2007 Schimmer Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy Mol Cancer Ther 6 24 30 10.1158/1535-7163.MCT-06-0443 1:CAS:528: DC%2BD2sXmsValsA%3D%3D 17237263 (Pubitemid 46206665)
15. I Crnković-Mertens N Wagener J Semzow EF Gröne A Haferkamp M Hohenfellner K Butz F Hoppe-Seyler 2007 Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis Cell Mol Life Sci 64 1137 1144 10.1007/s00018-007-6510-7 17437058 (Pubitemid 46684550)
16. B Liu M Han JK Wen L Wang 2007 Livin/ML-IAP as a new target for cancer treatment Cancer Lett 250 168 176 10.1016/j.canlet.2006.09.024 1:CAS:528:DC%2BD2sXjvFGqtLk%3D 17218055 (Pubitemid 46529441)
17. SB Bratton J Lewis M Butterworth CS Duckett GM Cohen 2002 XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis Cell Death Differ 9 881 892 10.1038/sj.cdd. 4401069 1:CAS:528:DC%2BD38XmtVOmsr0%3D 12181739 (Pubitemid 35023604)
18. BP Eckelman GS Salvesen 2006 The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases J Biol Chem 281 3254 3260 10.1074/jbc.M510863200 1:CAS:528:DC%2BD28XhtFSmsrk%3D 16339151 (Pubitemid 43845937)
19. N Roy QL Deveraux R Takahashi GS Salvesen JC Reed 1997 The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases EMBO J 16 6914 6925 10.1093/emboj/16.23.6914 1:CAS:528:DyaK1cXisVCitA%3D%3D 9384571
20. MG Sanna J da Silva Correia Y Luo B Chuang LM Paulson B Nguyen QL Deveraux RJ Ulevitch 2002 ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis J Biol Chem 277 30454 30462 10.1074/jbc.M203312200 1:CAS:528:DC%2BD38XmsFyqsbo%3D 12048196 (Pubitemid 34970736)
21. MG Sanna J da Silva Correia O Ducrey J Lee K Nomoto N Schrantz QL Deveraux RJ Ulevitch 2002 IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition Mol Cell Biol 22 1754 1766 10.1128/MCB.22.6.1754-1766.2002 1:CAS:528:DC%2BD38XitVWjtLk%3D 11865055 (Pubitemid 34174993)
22. HR Li ChenG ChenYS BS Xie LF Lin 2008 Expression of livin in lung cancer tissue and its relationship with the expression of caspase-3 Chinese-German J Clin Oncol 7 383 386 10.1007/s10330-008-0055-6 1:CAS:528:DC%2BD1cXhtVWrsrbJ
23. MT McManus PA Sharp 2002 Gene silencing in mammals by small interfering RNAs Nat Rev Genet 3 737 747 10.1038/nrg908 1:CAS:528:DC%2BD38XnsVGqs7k%3D 12360232
24. J Martinez A Patkaniowska SM Elbashir J Harborth M Hossbach H Urlaub J Meyer K Weber K Vandenburgh H Manninga SA Scaringe R Luehrmann T Tuschl 2002 Analysis of gene function in somatic mammalian cells using small interfering RNAs Methods 26 2 199 213 10.1016/S1046-2023(02)00023-3 (Pubitemid 34969582)
25. H Wang SS Tan XY Wang DH Liu CS Yu ZL Bai DL He J Zhao 2007 Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells Acta Pharmacol Sin 28 1968 1974 10.1111/j.1745-7254.2007.00724.x 1:CAS:528:DC%2BD2sXhsVGlsbjE 18031611 (Pubitemid 350198352)
26. I Crnković-Mertens J Semzow F Hoppe-Seyler K Butz 2006 Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells J Mol Med 84 232 240 10.1007/s00109-005-0021-5 16437214 (Pubitemid 43291012)
27. I Crnkovic-Mertens F Hoppe-Seyler K Butz 2003 Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene Oncogene 22 8330 8336 10.1038/sj.onc.1206973 1:CAS:528:DC%2BD3sXovVyms78%3D 14614456 (Pubitemid 37485525)
28. I Crnković-Mertens T Muley M Meister B Hartenstein J Semzow K Butz F Hoppe-Seyler 2006 The anti-apoptotic livin gene is an important determinant for the apoptotic resistance of non-small cell lung cancer cells Lung Cancer 54 135 142 10.1016/j.lungcan.2006.07.018 16965834 (Pubitemid 44767539)
29. T Dull R Zufferey M Kelly RJ Mandel M Nguyen D Trono L Naldini 1998 A third -generation lentivirus vector with a conditional packaging system J Virol 72 8463 8471 1:CAS:528:DyaK1cXmslaisbc%3D 9765382
30. R Hofer-Warbinek JA Schmid C Stehlik BR Binder J Lipp R de Martin 2000 Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1 J Biol Chem 275 22064 22068 10.1074/jbc.M910346199 1:CAS:528:DC%2BD3cXlt1ehtLY%3D 10807933 (Pubitemid 30621784)
31. GM Kasof BC Gomes 2001 Livin, a novel inhibitor of apoptosis protein family member J Biol Chem 276 3238 3246 10.1074/jbc.M003670200 1:CAS:528:DC%2BD3MXhtFWjurg%3D 11024045