TAQIB and I405V polymorphisms of CETP are moderately associated with obesity risk in the Chinese adult population

Acta Diabetologica

Volumn 47, Issue 3, 2010, Pages 217-224

  Ruan, Xiaoyang ^a,b   Ma, Lina ^a   Wang, Shuyu ^a   Lindpaintner, Klaus ^c   Liu, Xiangjun ^d   Wang, Binbin ^e   Peng, Zuoqi ^e   Ma, Xu ^e,f   Cheng, Maosheng ^b   Zhang, Jinghai ^b   Liu, Lisheng ^a   Wang, Xingyu ^a,g  

^a Beijing Hypertension League Institute   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d Tsinghua University   (China)

^e NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^f PEKING UNION MEDICAL COLLEGE   (China)

^g NONE   (China)

Author keywords

Chinese adult; Genotype; HDL; Obesity

Indexed keywords

CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; ISOLEUCINE; PROTEIN TAQIB; UNCLASSIFIED DRUG; VALINE;

ADULT; ALLELE; ARTICLE; BODY FAT DISTRIBUTION; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN VARIANT; SKINFOLD THICKNESS; WAIST CIRCUMFERENCE;

EID: 77955652699     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-009-0117-4     Document Type: Article

References (35)

1. D Drayna AS Jarnagin J McLean, et al. 1987 Cloning and sequencing of human cholesteryl ester transfer protein cDNA Nature 327 632 634 10.1038/327632a0 1:CAS:528:DyaL2sXmtFaksbc%3D 3600759 (Pubitemid 17086900)
2. Barter PJ (2002) Hugh Sinclair lecture: the regulation and remodelling of HDL by plasma factors. Atheroscler Suppl 3:39-47
3. B Lamarche KD Uffelman A Carpentier, et al. 1999 Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men J Clin Invest 103 1191 1199 10.1172/JCI5286 1:CAS:528:DyaK1MXis1Gnsbk%3D 10207171
4. WA Van der Steeg JA Kuivenhoven AH Klerkx SM Boekholdt GK Hovingh JJ Kastelein 2004 Role of CETP inhibitors in the treatment of dyslipidemia Curr Opin Lipidol 15 631 636 10.1097/00041433-200412000-00002 15529021 (Pubitemid 39612980)
5. ME Whitlock TL Swenson R Ramakrishnan, et al. 1989 Monoclonal antibody inhibition of cholesteryl ester transfer protein activity in the rabbit. Effects on lipoprotein composition and high density lipoprotein cholesteryl ester metabolism J Clin Invest 84 129 137 10.1172/JCI114132 1:CAS:528: DyaL1MXkslGhurg%3D 2738149
6. M Abbey GD Calvert 1989 Effects of blocking plasma lipid transfer protein activity in the rabbit Biochim Biophys Acta 1003 20 29 1:CAS:528: DyaL1MXktVCqsLc%3D 2713392 (Pubitemid 19124004)
7. F Benoist P Lau M McDonnell H Doelle R Milne R McPherson 1997 Cholesteryl ester transfer protein mediates selective uptake of high density lipoprotein cholesteryl esters by human adipose tissue J Biol Chem 272 23572 23577 10.1074/jbc.272.38.23572 1:CAS:528:DyaK2sXmtlOksL0%3D 9295295 (Pubitemid 27410927)
8. XC Jiang P Moulin E Quinet, et al. 1991 Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA J Biol Chem 266 4631 4639 1:CAS:528:DyaK3MXhs1Wgt7g%3D 1999438
9. RP Dullaart WJ Sluiter LD Dikkeschei K Hoogenberg A Van Tol 1994 Effect of adiposity on plasma lipid transfer protein activities: a possible link between insulin resistance and high density lipoprotein metabolism Eur J Clin Invest 24 188 194 10.1111/j.1365-2362.1994.tb00987.x 1:CAS:528: DyaK2cXktVKmtbk%3D 8033953
10. T Arai S Yamashita K Hirano, et al. 1994 Increased plasma cholesteryl ester transfer protein in obese subjects. A possible mechanism for the reduction of serum HDL cholesterol levels in obesity Arterioscler Thromb 14 1129 1136 1:STN:280:DyaK2c3ovFChsA%3D%3D 8018669
11. H Hayashibe K Asayama T Nakane N Uchida Y Kawada S Nakazawa 1997 Increased plasma cholesteryl ester transfer activity in obese children Atherosclerosis 129 53 58 10.1016/S0021-9150(96)06014-5 1:CAS:528: DyaK2sXhsFKmtr8%3D 9069517 (Pubitemid 27104250)
12. G Vassiliou R McPherson 2004 Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes J Lipid Res 45 1683 1693 10.1194/jlr.M400051-JLR200 1:CAS:528: DC%2BD2cXnvVWhtLg%3D 15231851 (Pubitemid 39296208)
13. I Kondo K Berg D Drayna R Lawn 1989 DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels Clin Genet 35 49 56 10.1111/j.1399-0004.1989.tb02904.x 1:STN:280:DyaL1M7mvVyhtA%3D%3D 2564326
14. V Gudnason S Kakko V Nicaud, et al. 1999 Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. The EARS Group Eur J Clin Invest 29 116 128 10.1046/j.1365-2362.1999.00412.x 1:CAS:528:DyaK1MXhs12nur0%3D 10092998 (Pubitemid 29090250)
15. K Ikewaki H Mabuchi T Teramoto, et al. 2003 Association of cholesteryl ester transfer protein activity and TaqIB polymorphism with lipoprotein variations in Japanese subjects Metabolism 52 1564 1570 10.1016/j.metabol.2003. 07.011 1:CAS:528:DC%2BD3sXpsVSnurs%3D 14669156 (Pubitemid 38049272)
16. ME Brousseau JJ O'Connor Jr JM Ordovas, et al. 2002 Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial Arterioscler Thromb Vasc Biol 22 1148 1154 10.1161/01.ATV.0000024566.57589.2E 1:CAS:528:DC%2BD38XlsFShu7c%3D 12117730 (Pubitemid 34764866)
17. N Barzilai G Atzmon C Schechter, et al. 2003 Unique lipoprotein phenotype and genotype associated with exceptional longevity JAMA 290 2030 2040 10.1001/jama.290.15.2030 1:CAS:528:DC%2BD3sXot1KmtbY%3D 14559957 (Pubitemid 37430586)
18. GA Rose H Blackburn RF Gillum RJ Prineas 1982 Cardiovascular survey methods WHO Monogr Ser 56 162 165
19. WT Friedewald RI Levy DS Fredrickson 1972 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clin Chem 18 499 502 1:CAS:528:DyaE38Xkslagsbw%3D 4337382
20. Helms C (1990) Method: manual isolation of human DNA from lymphoblasts or whole blood. CRI laboratory manual: RFLPs project
21. F Fumeron D Betoulle G Luc, et al. 1995 Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction J Clin Invest 96 1664 1671 10.1172/JCI118207 1:CAS:528:DyaK2MXnvVGqu7k%3D 7657837
22. B Gerholm-Larsen BG Nordestgaard R Steffensen G Jensen A Tybjaerg-Hansen 2000 Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene Circulation 101 1907 1912
23. K Takahashi XC Jiang N Sakai, et al. 1993 A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins J Clin Invest 92 2060 2064 10.1172/JCI116802 1:CAS:528:DyaK2cXivVGhsA%3D%3D 8408659
24. A Sandhofer T Tatarczyk M Laimer, et al. 2008 The Taq1B-variant in the cholesteryl ester-transfer protein gene and the risk of metabolic syndrome Obesity (Silver Spring) 16 919 922 10.1038/oby.2007.130 1:CAS:528: DC%2BD1cXktVWgt7Y%3D (Pubitemid 351465656)
25. ZY Huang HW Guo ZH Xu K Xue 2006 Association of gene polymorphism at cholesterol ester transfer protein locus with obesity and response to dietary intervention in obesity Wei Sheng Yan Jiu 35 447 449 1:CAS:528: DC%2BD2sXktFSqtb0%3D 16986521
26. N Srivastava BR Achyut J Prakash CG Agarwal DC Pant B Mittal 2008 Association of cholesteryl ester transfer protein (TaqIB) and apolipoprotein E (HhaI) gene variants with obesity Mol Cell Biochem 314 171 177 10.1007/s11010-008-9778-5 1:CAS:528:DC%2BD1cXntFKnur8%3D 18454345
27. H Lu A Inazu Y Moriyama, et al. 2003 Haplotype analyses of cholesteryl ester transfer protein gene promoter: a clue to an unsolved mystery of TaqIB polymorphism J Mol Med 81 246 255 1:CAS:528:DC%2BD3sXivFygsrw%3D 12700892
28. E Frisdal AH Klerkx GW Le, et al. 2005 Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study Hum Mol Genet 14 2607 2618 10.1093/hmg/ddi291 1:CAS:528: DC%2BD2MXpvFeru7w%3D 16049032 (Pubitemid 41300635)
29. C Dachet O Poirier F Cambien J Chapman M Rouis 2000 New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation Arterioscler Thromb Vasc Biol 20 507 515 1:CAS:528:DC%2BD3cXht1yqs7c%3D 10669650
30. M Teran-Garcia JP Despres A Tremblay C Bouchard 2008 Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeeding Atherosclerosis 196 455 460 10.1016/j.atherosclerosis. 2006.12.005 1:CAS:528:DC%2BD1cXpt12huw%3D%3D 17196207
31. JC Cohen E Boerwinkle TH Mosley Jr HH Hobbs 2006 Sequence variations in PCSK9, low LDL, and protection against coronary heart disease N Engl J Med 354 1264 1272 10.1056/NEJMoa054013 1:CAS:528:DC%2BD28Xislequr8%3D 16554528
32. C Green JL Oncley ML Karnovsky 1960 Lipid composition of lipoproteins of normal human plasma J Biol Chem 235 2884 2888 1:CAS:528:DyaF3MXhtlOlsQ%3D%3D 13708159
33. A Festa R D'Agostino Jr L Mykkanen, et al. 1999 LDL particle size in relation to insulin, proinsulin, and insulin sensitivity. The Insulin Resistance Atherosclerosis Study Diabetes Care 22 1688 1693 10.2337/diacare.22.10.1688 1:STN:280:DyaK1MvlsFKmtA%3D%3D 10526736 (Pubitemid 29458394)
34. J Hulthe L Bokemark J Wikstrand B Fagerberg 2000 The metabolic syndrome, LDL particle size, and atherosclerosis: the Atherosclerosis and Insulin Resistance (AIR) study Arterioscler Thromb Vasc Biol 20 2140 2147 1:CAS:528:DC%2BD3cXntV2itLs%3D 10978261
35. AR Tall 1990 Plasma high density lipoproteins. Metabolism and relationship to atherogenesis J Clin Invest 86 379 384 10.1172/JCI114722 1:CAS:528:DyaK3cXlt12qt7s%3D 2200802