Association of cholesteryl ester transfer protein (Taq IB) and apolipoprotein E (Hha I) gene variants with obesity

Molecular and Cellular Biochemistry

Volumn 314, Issue 1-2, 2008, Pages 171-177

  Srivastava, Neena ^a   Achyut, B R ^b   Prakash, Jai ^a   Agarwal, C G ^a   Pant, D C ^a   Mittal, Balraj ^b  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Hypertension; Lipoprotein; Metabolism; Obesity; Risk

Indexed keywords

APOLIPOPROTEIN E4; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ALLELE; ARTICLE; BODY MASS; CASE CONTROL STUDY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; INDIAN; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; OBESITY; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SYSTOLIC BLOOD PRESSURE;

APOLIPOPROTEINS E; BLOOD PRESSURE; BODY MASS INDEX; CHOLESTEROL ESTER TRANSFER PROTEINS; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INDIA; LINKAGE (GENETICS); LIPIDS; OBESITY; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 45449093560     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9778-5     Document Type: Article

References (43)

1. Executive summary of the third report of the national cholesterol education programme (NCEP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA 285:2486-2497 (2001)
2. Goodpasture BH, Thaete FL, Simoneau JA et al (1997) Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579-1585
3. Abate N, Garg A, Peshock RM et al (1995) Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest 96:88-98
4. Imbeault P, Lemieux S, Prud'homme D et al (1999) Relationship of visceral adipose tissue to metabolic risk factors for coronary heart disease: Is there a contribution of subcutaneous fat cell hypertrophy? Metabolism 48:355-362
5. Reaven GM (1995) Pathophysiology of insulin resistance in human diseases. Physiol Rev 75:473-486
6. National Cholesterol Education Programme (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) (2002) Third report of the national cholesterol education programme (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation 106:3143-3421
7. Engeli S, Bohnke J, Gorzelniak K et al (2005) Weight loss and the renin angiotensin aldosterone system. Hypertension 45:356-362
8. Vincent S, Planells R, Defoort C et al (2002) Genetic polymorphisms and lipoprotein responses to diets. Proc Nutr Soc 61(4):427-434
9. Freeman DJ, Griffin BA, Holmes AP et al (1994) Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity. Arterioscler Thromb 14:336-344
10. Fidani L, Goulas A, Crook R et al (2004) An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset alzheimer's disease. Neurosci Lett 357:152-154
11. Dixit M, Bhattacharya S, Mittal B (2005) Association of CETP TaqI and APOE polymorphisms with type II diabetes mellitus in North Indians: A case control study. BMC Endocr Disord 1:5-7
12. Utermann G (1987) Apolipoprotein E polymorphism in health and disease. Am Heart J 113:433-440
13. Marques-Vidal P, Bongard V, Ruidavets JB et al (2003) Obesity and alcohol modulate the effect of apolipoprotein E polymorphism on lipids and insulin. Obes Res 11(10):1200-1206
14. Zhang X, Xia G, Mai G (2001) Effects of polymorphism of apolipoprotein E gene on body mass index and plasma lipid levels in obese children. Zhonghua Yu Fang Yi Xue Za Zhi 35(6):412-414
15. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
16. Tietz NW (1994) Clinical guide to laboratory tests, 2nd edn. W. B. Saunders, Philadelphia, pp 1073-1091
17. Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502
18. Young DS, Pestaner LC, Gibberman V (1975) Effects of drugs on clinical laboratory tests. Clin Chem 21(5):1D-432D
19. Gao J, Katagiri H, Ishigaki Y et al (2007) Involvement of apolipoprotein E in excess fat accumulation and insulin resistance. Diabetes 56:24-33
20. Long JR, Liu P-Y, Liu Y-J et al (2003) APOE and TGF-b1 genes are associated with obesity phenotypes. J Med Genet 40:918-924
21. Guerra A, Rego C, Castro EM et al (2003) Influence of apolipoprotein polymorphism on cardiovascular risk factors in obese children. Ann Nutr Metab 47(2):49-54
22. Medina-Urrutia AX, Cardoso-Saldana GC, Zamora-Gonzalez J et al (2004) Apolipoprotein E polymorphism is related to plasma lipids and apolipoproteins in Mexican adolescents. Hum Biol 76(4):605-614
23. Zaman MM, Ikemoto S, Yoshiike N et al (1997) Association of apolipoprotein genetic polymorphisms with plasma cholesterol in a Japanese rural population. The Shibata Study. Arterioscler Thromb Vasc Biol 17(12):3495-3504
24. Haddy N, De Bacquer D, Chemaly MM et al (2002) The importance of plasma apolipoprotein E concentration in addition to its common polymorphism on inter-individual variation in lipid levels: Results from Apo Europe. Eur J Hum Genet 10(12):841-850
25. Katsuya T, Baba S, Ishikawa K et al (2002) Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: The Suita Study. J Hypertens 20(10):2017-2021
26. Stiefel P, Montilla C, Muniz-Grijalvo O et al (2001) Apolipoprotein E gene polymorphism is related to metabolic abnormalities, but does not influence erythrocyte membrane lipid composition or sodium-lithium countertransport activity in essential hypertension. Metabolism 50(2):157-160
27. Bhavani AB, Sastry KB, Reddy NK (2005) Lipid profile and apolipoprotein E polymorphism in essential hypertension. Indian Heart J 57(2):151-157
28. Srinivasan SR, Ehnholm C, Wattigney WA et al (1996) The relation of apolipoprotein E polymorphism to multiple cardiovascular risk in children: The Bogalusa Heart Study. Atherosclerosis 123(1-2):33-42
29. Kivipelto M, Helkala EL, Laakso MP et al (2002) Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med 137(3):149-155
30. Padmaja N, Ravindra KM, Soya SS et al (2007) Common variants of Cholesteryl ester transfer protein gene and their association with lipid parameters in healthy volunteers of Tamilian population. Clin Chim Acta 375(1-2):140-146
31. Corella D, Saiz C, Guillen M et al (2000) Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population. Atherosclerosis 152:367-376
32. Boekholdt SM, Sacks FM, Jukema JW et al (2005) Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. Circulation 111:278-287
33. Kakko S, Tamminen M, Paivansalo M et al (2001) Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness. Eur J Clin Invest 31:593-602
34. Goto A, Sasai K, Suzuki S et al (2001) Cholesteryl ester transfer protein and atherosclerosis in Japanese subjects: A study based on coronary angiography. Atherosclerosis 159:153-163
35. Tai ES, Ordovas JM, Corella D et al (2003) The TaqIB and -629C>A polymorphisms at the cholesteryl ester transfer protein locus: associations with lipid levels in a multiethnic population. The 1998 Singapore National Health Survey. Clin Genet 63:19-30
36. Susanna EB, Hans LH, Bruce HR et al (2005) The effect of cholesteryl ester transfer protein-629C3A promoter polymorphism on high-density lipoprotein cholesterol is dependent on serum triglycerides. J Clin Endocrinol Metab 90:4198-4202
37. Kuivenhoven JA, de Knijff P, Boer JM et al (1997) Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels. Arterioscler Thromb Vasc Biol 17:560-568
38. Klerkx AH, Tanck MW, Kastelein JJ et al (2003) Haplotype analysis of the CETP gene: Not TaqIB, but the closely linked - 629CA polymorphism and a novel promoter variant are independently associated with CETP concentration. Hum Mol Genet 12:111-123
39. Mather HM, Chaturvedi N, Fuller JH (1998) Mortality and morbidity from diabetes in South Asians and Europeans; 11-year follow-up of the Southall Diabetes Survey, London, UK. Diabetes Med 15:53-59
40. Deurenberg-Yap M, Li T, Tan WL, et al. (2001) Can dietary factors explain differences in serum cholesterol profiles among different ethnic groups (Chinese, Malays and Indians) in Singapore. Asia Pacif J Clin Nutr 10:39-45
41. Corella D, Guillen M, Saiz C et al (2001) Environmental factors modulate the effect of the APOE genetic polymorphism on plasma lipid concentrations: Ecogenetic studies in a Mediterranean Spanish population. Metabolism 50:936-944
42. Wilson PW, Myers RH, Larson MG et al (1994) Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study. J Am Med Assoc 272:1666-1671
43. Lahoz C, Schaefer EJ, Cupples LA et al (2001) Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis 154:529-537