Analysis of neuronal nitric oxide synthase expression and increasing astrogliosis in the brain of senescence-accelerated-prone 8 mice

International Journal of Neuroscience

Volumn 120, Issue 9, 2010, Pages 602-608

  Han, Shu ^a   Rudd, John A ^b   Hu, Zhi Ying ^c   Zhang, Lihong ^b   Yew, David T ^b   Fang, Marong ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c HANGZHOU RED CROSS HOSPITAL   (China)

Author keywords

Age related astrogliosis; Learning and memory deficits; NNOS; NO; Senescence accelerated mouse

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN; CONTROLLED STUDY; DOWN REGULATION; FRONTAL CORTEX; HIPPOCAMPUS; LEARNING DISORDER; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SENESCENCE ACCELERATED MOUSE; UPREGULATION;

AGING; ANIMALS; BRAIN; CEREBRAL CORTEX; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HIPPOCAMPUS; MALE; MEMORY; MICE; MICE, MUTANT STRAINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I;

EID: 77955651624     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207454.2010.503911     Document Type: Article

References (27)

1. Bon, C. L., & Garthwaite, J. (2003). On the role of nitric oxide in hippocampal long-term potentiation. The Journal of Neuroscience, 23, 1941-1948.
2. Butterfeld, D. A., & Poon, H. F. (2005). The senescence-accelerated prone mouse (SAMP8): A model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease. Experimental Gerontology, 40, 774-783.
3. Colas, D., Gharib, A., Bezin, L., Morales, A., Guidon, G., Cespuglio, R., et al. (2006). Regional age-related changes in neuronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain. BMC Neuroscience, 7, 81.
4. Costa, S., Planchenault, T., Charriere-Bertrand, C., Mouchel, Y., Fages, C., & Juliano, S. (2002). Astroglial permissivity for neu-ritic outgrowth in neuron-astrocyte cocultures depends on regulation of laminin bioavailability. Glia, 37, 105-113.
5. Dawson, V. L., Dawson, T. M., Bartley, D. A., Uhl, G. R., & Sny-der, S. H. (1993). Mechanisms of nitric oxide-mediated neuro-toxicity in primary brain cultures. The Journal of Neuroscience, 3, 2651-2661.
6. Flood, J. F., & Morley, J. E. (1993). Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM). Neurobiology of Aging, 14, 153-157.
7. Finch, C. E. (2003). Neurons, glia, and plasticity in normal brain aging. Neurobiology of Aging, 24, S123-S127.
8. Gibbs, S. M. (2003). Regulation of neuronal proliferation and differentiation by nitric oxide. Molecular Neurobiology, 27, 107-120.
9. H ölscher, C. (1997). Nitric oxide, the enigmatic neuronal messenger: Its role in synaptic plasticity. Trends in Neurosciences, 20, 298-303.
10. Inada, K., Yokoi, I., Kabuto, H., Habu, H., Mori, A., & Ogawa, N. (1996). Age-related increase in nitric oxide synthase activity in senescence accelerated mouse brain and the effect of long-term administration of superoxide radical scavenger. Mechanisma of Ageing and Development, 89, 95-102.
11. Law, A., Gauthier, S., & Quirion, R. (2001). Say NO to Alzheimer's disease: The putative links between nitric oxide and dementia of the Alzheimer's type. Brain Research Reviews, 35, 73-96.
12. Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2003). Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus. Neuroscience, 119, 679-687.
13. Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2004a). Potential involvement of NOS and arginase in age-related behavioural impairments. Experimental Gerontology, 39, 1207-1222.
14. Liu, P., Smith, P. F., Appleton, I., Darlington, C. L., & Bilkey, D. K. (2004b). Age-related changes in nitric oxide synthase and arginase in the rat prefrontal cortex. Neurobiology of Aging, 25, 547-552.
15. Meshul, C. K., Seil, F. J., & Herndon, R. M. (1987). Astrocytes play a role in regulation of synaptic density. Brain Research, 402, 139-145.
16. Meyer, R. C., Spangler, E. L., Kametani, H., & Ingram, D. K. (1996). Age-associated memory impairment. Assessing the role of nitric oxide. Annals of the New York Academy of Sciences, 854, 307-317.
17. Miyamoto, M. (1997). Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10. Experimental Gerontology, 32, 139-148.
18. Phillips, K. G., Hardingham, N. R., & Fox, K. (2008). Postsynaptic action potentials are required for nitric-oxide-dependent long-term potentiation in CA1 neurons of adult GluR1 knock-out and wild-type mice. The Journal of Neuroscience, 28, 14031-14041.
19. Rozovsky, I., Wei, M., Stone, D. J., Zanjani, H., Anderson, C. P., & Morgan, T. E. (2002). Estradiol (E2) enhances neurite outgrowth by repressing glial fbrillary acidic protein expression and reorganizing laminin. Endocrinology, 143, 636-646.
20. Shibuki, K., & Okada, D. (1991). Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature, 349, 326-328.
21. Snyder, S. H., & Bredt, D. S. (1992). Biological roles of nitric oxide. Scientific American, 266, 68-71, 74-77.
22. Stepanichev, M. Y., Onufriev, M. V., Yakovlev, A. A., Khrenov, A. I., Peregud, D. I., Vorontsova, O. N., et al. (2008). Amyloid-beta (25-35) increases activity of neuronal NO-synthase in rat brain. Neurochemistry International, 52, 1114-1124.
23. Takeda, T., Hosokawa, M., Takeshita, S., Irino, M., Higuchi, K., Matsushita, T., et al.(1981). A new murine model of accelerated senescence. Mechanisma of Ageing and Development, 17, 183-194.
24. Wu, Y., Zhang, A. Q., & Yew, D. T. (2005). Age related changes of various markers of astrocytes in senescence-accelerated mice hippocampus. Neurochemistry International, 46, 565-574.
25. Xia, Y., Dawson, V. L., Dawson, T. M., Snyder, S. H., & Zweier, J. L. (1996). Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proceedings of the National Academy of Sciences of the United States of America, 93, 6770-6774.
26. Zhang, J., & Snyder, S. H. (1995). Nitric oxide in the nervous system. Annual Review of Pharmacology and Toxicology, 35, 213-233.
27. Abel, T., Nguyen, P. V., Barad, M., Deuel, T. A., Kandel, E. R., & Bourtchouladze, R. (1997). Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell, 88, 615-626.