Bradykinin modulation of tumor vasculature: II. Activation ofnitric oxide and phospholipase A2/prostaglandinsignaling pathways synergistically modifies vascular physiology andmorphology to enhance delivery of chemotherapeutic agents to tumors

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 632-641

  Emerich, Dwaine F ^a   Dean, Reginald L ^a   Snodgrass, Pamela ^a   Lafreniere, Denise ^a   Agostino, Mary ^a   Wiens, Tania ^a   Xiong, Hua ^a   Hasler, Brant ^a   Marsh, Joanne ^a   Pink, Melissa ^a   Kim, Byong Su ^a   Perdomo, Brigido ^a   Bartus, Raymond T ^a  

^a ALKERMES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ RECEPTOR AGONIST; CARBOPLATIN; LOBRADIMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; HYDROPHILICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SOLID TUMOR; TISSUE PRESSURE; TUMOR GROWTH; TUMOR VASCULARIZATION;

ALGORITHMS; ANIMALS; ANTINEOPLASTIC AGENTS; AUTORADIOGRAPHY; BIOTRANSFORMATION; BLOOD PRESSURE; BLOOD VESSELS; BRADYKININ; EXTRACELLULAR SPACE; IMMUNOHISTOCHEMISTRY; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NITRIC OXIDE; PHOSPHOLIPASES A; POROSITY; PROSTAGLANDINS; RATS; RATS, INBRED F344; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0035146475     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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