Serotonin transporter gene associations with psychopathic traits in youth vary as a function of socioeconomic resources

Journal of Abnormal Psychology

Volumn 119, Issue 3, 2010, Pages 604-609

  Sadeh, Naomi ^a   Javdani, Shabnam ^a   Jackson, Joshua J ^a   Reynolds, Elizabeth K ^b   Potenza, Marc N ^c   Gelernter, Joel ^c   Lejuez, C W ^b   Verona, Edelyn ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 HTT; Psychopathic tendencies; Serotonin; Socioeconomic status

Indexed keywords

SEROTONIN TRANSPORTER;

ADOLESCENT; ARTICLE; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; EMOTIONAL DISORDER; FEMALE; GENE FREQUENCY; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HOMOZYGOSITY; HUMAN; IMPULSIVENESS; JUVENILE; MAJOR CLINICAL STUDY; MALE; NARCISSISM; PSYCHOPATHY; SOCIAL STATUS;

EID: 77955620904     PISSN: 0021843X     EISSN: 19391846     Source Type: Journal    
DOI: 10.1037/a0019709     Document Type: Article

References (33)

1. Beitchman J.H., Baldassarra L., Mik H., De Luca V., King N., Bender D., Kennedy J.L. Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. The American Journal of Psychiatry 2006, 163:1103-1105.
2. Belsky J. Differential susceptibility to rearing influences: An evolutionary hypothesis and some evidence. Origins of the social mind: Evolutionary psychology and child development 2005, 139-163. Guilford Press, New York, NY. B. Ellis, D. Bjorklund (Eds.).
3. Belsky J., Pluess M. The nature (and nurture?) of plasticity in early human development. Perspectives on Psychological Science 2009, 4:345-351.
4. Bertolino A., Arciero G., Rubino V., Latorre V., De Candia M., Mazzola V., Scarabino T. Variation of human amygdala response during threatening stimuli as a function of 5'HTTLPR genotype and personality style. Biological Psychiatry 2005, 57:1517-1525.
5. Boyce W.T., Ellis B.J. Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Development and Psychopathology 2005, 17:271-301.
6. Canli T., Lesch K. Long story short: The serotonin transporter in emotion regulation and social cognition. Nature Neuroscience 2007, 10:1103-1109.
7. Canli T., Omura K., Haas B.W., Fallgatter A., Constable R.T., Lesch K.P. Beyond affect: A role for genetic variation of the serotonin transporter in neural activation during a cognitive attention task. PNAS 2005, 102:12224-12229.
8. Carver C.S., Miller C.J. Relations of serotonin function to personality: Current views and a key methodological issue. Psychiatry Research 2006, 144:1015.
9. Caspi A., McClay J., Moffitt T.E., Mill J., Martin J., Craig I.W., Poulton R. Role of genotype in the cycle of violence in maltreated children. Science 2002, August 2, 297:851-854.
10. Dolan M.C., Anderson I.M. The relationship between serotonergic function and the Psychopathy Checklist: Screening Version. Journal of Psychopharmacology 2003, 17:216-222.
11. Essau C.A., Sasagawa S., Frick P.J. Callous-unemotional traits in a community sample of adolescents. Assessment 2006, 13:454-469.
12. Frick, P. J. (2003). The Inventory of Callous-Unemotional Traits. Unpublished rating scale, The University of New Orleans, New Orleans, Louisiana.
13. Frick P.J., Bodin S.D., Barry C.T. Psychopathic traits and conduct problems in community and clinic-referred children. Psychological Assessment 2000, 12:382-393.
14. Frick P.J., Hare R.D. The Antisocial Process Screening Device 2001, Multi-Health Systems, Toronto, Ontario, Canada.
15. Frick P.J., Kimonis E.R., Dandreaux D.M., Farell J.M. The 4 year stability of psychopathic traits in non-referred youth. Behavioral Sciences & the Law 2003, 21:713-736.
16. Gelernter J., Kranzler H., Cubells J.F. Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects. Human Genetics 1997, 101:243-246.
17. Greenberg B.D., Tolliver T.J., Huang S.J., Li Q., Bengel D., Murphy D.L. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. American Journal of Medical Genetics 1999, 88:83-87.
18. Haberstick B., Smolen J., Hewitt J. Family-based association test of the 5HTTLPR and aggressive behavior in a general population sample of children. Biological Psychiatry 2006, 59:836-843.
19. Hare R.D. Manual for the Hare Psychopathy Checklist-Revised 2003, Multi-Health Systems, Toronto, Ontario, Canada. 2nd ed.
20. Hariri A.R., Drabant E.M., Munoz K.E., Kolachana B.S., Mattay V.S., Egan M.F., Weinberger D.R. A susceptibility gene for affective disorders and the response of the human amygdala. Archives of General Psychiatry 2005, 62:146-152.
21. Hollingshead Four factor index of social status 1975, Yale University Press, New Haven, CT.
22. Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., Murphy D.L. Association of anxiety-related traits with a polymorphism in the serotonin tranporter gene regulatory region. Science 1996, November 29, 274:1527-1531.
23. Lykken D. The antisocial personalities 1995, Erlbaum, Hillsdale, NJ.
24. Monroe S.M., Reid M.W. Gene-environment interactions in depression research genetic polymorphisms and life-stress polyprocedures. Psychological Science 2008, 19:947-956.
25. Ni X., Chan K., Bulgin N., Sicard T., Bismil R., McMain S., Kennedy J.L. Association between serotonin transporter gene and borderline personality disorder. Journal of Psychiatric Research 2006, 40:448-453.
26. Patrick C.J., Bradley M.M., Lang P.J. Emotion in the criminal psychopath: Startle reflex modulation. Journal of Abnormal Psychology 1993, 102:82-92.
27. Poythress N.G., Dembo R., Wareham J., Greenbaum P.E. Construct validity of the Youth Psychopathic Traits Inventory (YPI) and Antisocial Process Screening Device (APSD) with justice involved adolescents. Criminal Justice and Behavior 2006, 33:26-55.
28. Raleigh M.J., McGuire M.T., Brammer G.L., Pollack D.B., Yuwiler A. Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys. Brain Research 1991, 559:181-190.
29. Risch N., Herrell R., Lehner T., Liang K.-L., Eaves L., Hoh J., Merikangas K.R. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression. JAMA 2009, 301:2462-2471.
30. Soderstrom H., Blennow K., Manhem A., Forsman A. CSF studies in violent offenders: I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy. Journal of Neural Transmission 2001, 108:869-878.
31. Soderstrom H., Blennow K., Sjodin A.K., Forsman A. New evidence for an association between the CSF HVA: 5-HIAA ratio and psychopathic traits. Journal of Neurology, Neurosurgery and Psychiatry 2003, 74:918-921.
32. Tang H., Quertermous T., Rodriguez B., Kardia S.L.R., Zhu X., Brown A., Risch N.J. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. American Journal of Human Genetics 2005, 76:268-275.
33. Tuvblad C., Grann M., Lichtenstein P. Heritability for adolescent antisocial behavior differs with socioeconomic status: Gene-environment interaction. Journal of Child Psychology and Psychiatry 2005, 47:734-743.