-
1
-
-
0031848636
-
Functional role of estrogen metabolism in target cells: Review and perspectives
-
Zhu B, Conney AH (1998) Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 19(1): 1-27.
-
(1998)
Carcinogenesis
, vol.19
, Issue.1
, pp. 1-27
-
-
Zhu, B.1
Conney, A.H.2
-
2
-
-
0033788285
-
Estrogen metabolism and risk of breast cancer: A prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women
-
Muti P, Bradlow HL, Micheli A, Krogh V, Freudenheim JL, Schünemann HJ, Stanulla M, Yang J, Sepkovic DW, Trevisan M, Berrino F (2000) Estrogen metabolism and risk of breast cancer: a prospective study of the 2: 16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women. Epidemiology 11(6): 635-640.
-
(2000)
Epidemiology
, vol.11
, Issue.6
, pp. 635-640
-
-
Muti, P.1
Bradlow, H.L.2
Micheli, A.3
Krogh, V.4
Freudenheim, J.L.5
Schünemann, H.J.6
Stanulla, M.7
Yang, J.8
Sepkovic, D.W.9
Trevisan, M.10
Berrino, F.11
-
3
-
-
48249145841
-
In vitro effects of 2-methoxyestradiol on MCF-12A and MCF-7 cell growth, morphology and mitotic spindle formation
-
van Zijl C, Lottering ML, Steffens F, Joubert A (2008) In vitro effects of 2-methoxyestradiol on MCF-12A and MCF-7 cell growth, morphology and mitotic spindle formation. Cell Biochem Funct 26(5): 632-642.
-
(2008)
Cell Biochem Funct
, vol.26
, Issue.5
, pp. 632-642
-
-
van Zijl, C.1
Lottering, M.L.2
Steffens, F.3
Joubert, A.4
-
4
-
-
0742269867
-
New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent
-
Mooberry SL (2003) New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Curr Opin Oncol 15(6): 425-430.
-
(2003)
Curr Opin Oncol
, vol.15
, Issue.6
, pp. 425-430
-
-
Mooberry, S.L.1
-
5
-
-
32544433479
-
Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors
-
Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D, Parr A, Nguyen D, Yang SX, Steinberg SM, Venitz J, Sparreboom A, Figg WD (2006) Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 5(1): 22-27.
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.1
, pp. 22-27
-
-
Dahut, W.L.1
Lakhani, N.J.2
Gulley, J.L.3
Arlen, P.M.4
Kohn, E.C.5
Kotz, H.6
McNally, D.7
Parr, A.8
Nguyen, D.9
Yang, S.X.10
Steinberg, S.M.11
Venitz, J.12
Sparreboom, A.13
Figg, W.D.14
-
6
-
-
69249212263
-
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: A Hoosier Oncology Group trial
-
Matei D, Schilder J, Sutton G, Perkins S, Breen T, Quon C, Sidor C (2009) Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial. Gynecol Oncol 115(1): 90-96.
-
(2009)
Gynecol Oncol
, vol.115
, Issue.1
, pp. 90-96
-
-
Matei, D.1
Schilder, J.2
Sutton, G.3
Perkins, S.4
Breen, T.5
Quon, C.6
Sidor, C.7
-
7
-
-
77955552654
-
-
Zhou Q, Gustafson D, Nallapareddy S, Diab S, Leong S, Lewis K, Gore L, Messersmith WA, Treston AM, Eckhardt SG, Sidor C, Camidge DR (2010) "A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer". Invest New Drugs.
-
-
-
-
8
-
-
71049183916
-
Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol
-
Agoston GE, Shah JH, Suwandi L, Hanson AD, Zhan X, LaVallee TM, Pribluda V, Treston AM (2009) Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol. Bioorg Med Chem Lett 19(21): 6241-6244.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.21
, pp. 6241-6244
-
-
Agoston, G.E.1
Shah, J.H.2
Suwandi, L.3
Hanson, A.D.4
Zhan, X.5
Lavallee, T.M.6
Pribluda, V.7
Treston, A.M.8
-
9
-
-
34247604099
-
In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol
-
Chander SK, Foster PA, Leese MP, Newman SP, Potter BV, Purohit A, Reed MJ (2007) In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol. Br J Cancer 96(9): 1368-1376.
-
(2007)
Br J Cancer
, vol.96
, Issue.9
, pp. 1368-1376
-
-
Chander, S.K.1
Foster, P.A.2
Leese, M.P.3
Newman, S.P.4
Potter, B.V.5
Purohit, A.6
Reed, M.J.7
-
10
-
-
0034528890
-
2-Methoxyestradiol: An endogenous antiangiogenic and antiproliferative drug candidate
-
Pribluda VS, Gubish ER Jr, Lavallee TM, Treston A, Swartz GM, Green SJ (2000) 2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate. Cancer Metastasis Rev 19(1-2): 173-179.
-
(2000)
Cancer Metastasis Rev
, vol.19
, Issue.1-2
, pp. 173-179
-
-
Pribluda, V.S.1
Gubish Jr., E.R.2
Lavallee, T.M.3
Treston, A.4
Swartz, G.M.5
Green, S.J.6
-
11
-
-
57649097524
-
-
Kato S, Sadarangani A, Lange S, Delpiano AM, Vargas M, Brañes J, Carvajal J, Lipkowitz S, Owen GI y Cuello MA (2008) "2-methoxyestradiol mediates apoptosis through caspase-dependent and independent mechanisms in ovarian cancer cells but not in normal counterparts". Reprod Sci (9): 878-894.
-
-
-
-
12
-
-
13944271914
-
-
Mulac-Jericevic B, Conneely OM (2005) "Reproductive tissue-selective actions of progesterone receptors". Ernst Schering Res Found Workshop (52): 19-37.
-
-
-
-
13
-
-
0034086140
-
Origins and evolutionary diversification of the nuclear receptor superfamily
-
Owen GI, Zelent A (2000) Origins and evolutionary diversification of the nuclear receptor superfamily. Cell Mol Life Sci 57(5): 809-827.
-
(2000)
Cell Mol Life Sci
, vol.57
, Issue.5
, pp. 809-827
-
-
Owen, G.I.1
Zelent, A.2
-
14
-
-
44549083120
-
The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression
-
Boonyaratanakornkit V, Bi Y, Rudd M, Edwards DP (2008) The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression. Steroids 73(9-10): 922-928.
-
(2008)
Steroids
, vol.73
, Issue.9-10
, pp. 922-928
-
-
Boonyaratanakornkit, V.1
Bi, Y.2
Rudd, M.3
Edwards, D.P.4
-
15
-
-
0032562712
-
Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300
-
Owen GI, Richer JK, Tung L, Takimoto G, Horwitz KB (1998) Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. J Biol Chem 273(17): 10696-10701.
-
(1998)
J Biol Chem
, vol.273
, Issue.17
, pp. 10696-10701
-
-
Owen, G.I.1
Richer, J.K.2
Tung, L.3
Takimoto, G.4
Horwitz, K.B.5
-
16
-
-
0032553553
-
Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity
-
Richer JK, Lange CA, Manning NG, Owen G, Powell R, Horwitz KB (1998) Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity. J Biol Chem 273(47): 31317-31326.
-
(1998)
J Biol Chem
, vol.273
, Issue.47
, pp. 31317-31326
-
-
Richer, J.K.1
Lange, C.A.2
Manning, N.G.3
Owen, G.4
Powell, R.5
Horwitz, K.B.6
-
17
-
-
38749140218
-
Integration of progesterone receptor action with rapid signaling events in breast cancer models
-
Lange CA (2008) Integration of progesterone receptor action with rapid signaling events in breast cancer models. J Steroid Biochem Mol Biol 108: 203-212.
-
(2008)
J Steroid Biochem Mol Biol
, vol.108
, pp. 203-212
-
-
Lange, C.A.1
-
18
-
-
58049218988
-
Non-genomic progesterone actions in female reproduction
-
Epub 2008 Oct 19
-
Gellersen B, Fernandes MS, Brosens JJ (2009) Non-genomic progesterone actions in female reproduction. Hum Reprod Updat 15(1): 119-138, Epub 2008 Oct 19.
-
(2009)
Hum Reprod Updat
, vol.15
, Issue.1
, pp. 119-138
-
-
Gellersen, B.1
Fernandes, M.S.2
Brosens, J.J.3
-
19
-
-
0042978662
-
MAP kinases couple multiple functions of human progesterone receptors: Degradation, transcriptional synergy, and nuclear association
-
Qiu M, Lange CA (2003) MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association. J Steroid Biochem Mol Biol 85(2-5): 147-157.
-
(2003)
J Steroid Biochem Mol Biol
, vol.85
, Issue.2-5
, pp. 147-157
-
-
Qiu, M.1
Lange, C.A.2
-
20
-
-
0042018741
-
Breast cancer and hormone-replacement therapy in the Million Women Study
-
Million Women Study Collaborators
-
Beral V, Million Women Study Collaborators (2003) Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 362(9382): 419-27.
-
(2003)
Lancet
, vol.362
, Issue.9382
, pp. 419-427
-
-
Beral, V.1
-
21
-
-
0037830132
-
Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: The women's health initiative randomized trial
-
WHI Investigators
-
Chlebowski RT, Hendrix SL, Langer RD, Stefanick ML, Gass M, Lane D, Rodabough RJ, Gilligan MA, Cyr MG, Thomson CA, Khandekar J, Petrovitch H, McTiernan A, WHI Investigators (2003) Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the women's health initiative randomized trial. JAMA 289(24): 3243-53.
-
(2003)
Jama
, vol.289
, Issue.24
, pp. 3243-3253
-
-
Chlebowski, R.T.1
Hendrix, S.L.2
Langer, R.D.3
Stefanick, M.L.4
Gass, M.5
Lane, D.6
Rodabough, R.J.7
Gilligan, M.A.8
Cyr, M.G.9
Thomson, C.A.10
Khandekar, J.11
Petrovitch, H.12
McTiernan, A.13
-
22
-
-
70349694075
-
Glucose transporters in sex steroid hormone related cancer
-
Nualart F, Los Angeles García M, Medina RA, Owen GI (2009) Glucose transporters in sex steroid hormone related cancer. Curr Vasc Pharmacol 7(4): 534-548.
-
(2009)
Curr Vasc Pharmacol
, vol.7
, Issue.4
, pp. 534-548
-
-
Nualart, F.1
Los Angeles García, M.2
Medina, R.A.3
Owen, G.I.4
-
23
-
-
20044395274
-
Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1
-
Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Sadarangani A, Villalon M, Brosens JJ, White JO, Richer JK, Horwitz KB, Owen GI (2005) Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1. J Clin Endocrinol Metab 90(2): 1181-1188.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, Issue.2
, pp. 1181-1188
-
-
Kato, S.1
Pinto, M.2
Carvajal, A.3
Espinoza, N.4
Monso, C.5
Sadarangani, A.6
Villalon, M.7
Brosens, J.J.8
White, J.O.9
Richer, J.K.10
Horwitz, K.B.11
Owen, G.I.12
-
24
-
-
4644360172
-
Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells
-
Medina RA, Meneses AM, Vera JC, Gúzman C, Nualart F, Rodriguez F, de los Angeles Garcia M, Kato S, Espinoza N, Monsó C, Carvajal A, Pinto M, Owen GI (2004) Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells. J Endocrinol 182(3): 467-78.
-
(2004)
J Endocrinol
, vol.182
, Issue.3
, pp. 467-478
-
-
Medina, R.A.1
Meneses, A.M.2
Vera, J.C.3
Gúzman, C.4
Nualart, F.5
Rodriguez, F.6
de los Angeles Garcia, M.7
Kato, S.8
Espinoza, N.9
Monsó, C.10
Carvajal, A.11
Pinto, M.12
Owen, G.I.13
-
25
-
-
0034911743
-
Tissue factor-a receptor involved in the control of cellular properties, including angiogenesis
-
Chen J, Bierhaus A, Schiekofer S, Andrassy M, Chen B, Stern DM, Nawroth PP (2001) Tissue factor-a receptor involved in the control of cellular properties, including angiogenesis. Thromb Haemost 86(1): 334-345.
-
(2001)
Thromb Haemost
, vol.86
, Issue.1
, pp. 334-345
-
-
Chen, J.1
Bierhaus, A.2
Schiekofer, S.3
Andrassy, M.4
Chen, B.5
Stern, D.M.6
Nawroth, P.P.7
-
26
-
-
0037085303
-
-
Richer JK, Jacobsen BM, Manning NG, Abel MG, Wolf DM, Horwitz KB (2002) "Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells". J Biol Chem 15; 277(7): 5209-18.
-
-
-
-
27
-
-
2442700125
-
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling
-
Belting M, Dorrell MI, Sandgren S, Aguilar E, Ahamed J, Dorfleutner A, Carmeliet P, Mueller BM, Friedlander M, Ruf W (2004) Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med 10(5): 502-509.
-
(2004)
Nat Med
, vol.10
, Issue.5
, pp. 502-509
-
-
Belting, M.1
Dorrell, M.I.2
Sandgren, S.3
Aguilar, E.4
Ahamed, J.5
Dorfleutner, A.6
Carmeliet, P.7
Mueller, B.M.8
Friedlander, M.9
Ruf, W.10
-
28
-
-
33746092472
-
Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells
-
Amarzguioui M, Peng Q, Wiiger MT, Vasovic V, Babaie E, Holen T, Nesland JM, Prydz H (2006) Ex vivo and in vivo delivery of anti-tissue factor short interfering RNA inhibits mouse pulmonary metastasis of B16 melanoma cells. Clin Cancer Res 12(13): 4055-4061.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.13
, pp. 4055-4061
-
-
Amarzguioui, M.1
Peng, Q.2
Wiiger, M.T.3
Vasovic, V.4
Babaie, E.5
Holen, T.6
Nesland, J.M.7
Prydz, H.8
-
30
-
-
0028007430
-
Procoagulant activity in cancer cells is dependent on tissue factor expression
-
Hu T, Bach RR, Horton R, Konigsberg WH, Todd MB (1994) Procoagulant activity in cancer cells is dependent on tissue factor expression. Oncol Res 6(7): 321-327.
-
(1994)
Oncol Res
, vol.6
, Issue.7
, pp. 321-327
-
-
Hu, T.1
Bach, R.R.2
Horton, R.3
Konigsberg, W.H.4
Todd, M.B.5
-
31
-
-
48949119478
-
Tissue factor, angiogenesis and tumour progression
-
Bluff JE, Brown NJ, Reed MW, Staton CA (2008) Tissue factor, angiogenesis and tumour progression. Breast Cancer Res 10(2): 204.
-
(2008)
Breast Cancer Res
, vol.10
, Issue.2
, pp. 204
-
-
Bluff, J.E.1
Brown, N.J.2
Reed, M.W.3
Staton, C.A.4
-
32
-
-
23744475201
-
Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells
-
Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Bravo L, Villalon M, Cuello M, Quest AF, Suenaga A, Brosens JJ, Owen GI (2005) Tissue factor is regulated by epidermal growth factor in normal and malignant human endometrial epithelial cells. Thromb Haemost 94(2): 444-453.
-
(2005)
Thromb Haemost
, vol.94
, Issue.2
, pp. 444-453
-
-
Kato, S.1
Pinto, M.2
Carvajal, A.3
Espinoza, N.4
Monso, C.5
Bravo, L.6
Villalon, M.7
Cuello, M.8
Quest, A.F.9
Suenaga, A.10
Brosens, J.J.11
Owen, G.I.12
-
33
-
-
16344381892
-
2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer
-
Sutherland TE, Schuliga M, Harris T, Eckhardt BL, Anderson RL, Quan L, Stewart AG (2005) 2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer. Clin Cancer Res 11(5): 1722-1732.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.5
, pp. 1722-1732
-
-
Sutherland, T.E.1
Schuliga, M.2
Harris, T.3
Eckhardt, B.L.4
Anderson, R.L.5
Quan, L.6
Stewart, A.G.7
-
34
-
-
0034638620
-
Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms
-
Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Korzekwa KR, Fingerle J, Jackson EK (2000) Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. Biochem Biophys Res Commun 278(1): 27-33.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, Issue.1
, pp. 27-33
-
-
Dubey, R.K.1
Gillespie, D.G.2
Zacharia, L.C.3
Rosselli, M.4
Korzekwa, K.R.5
Fingerle, J.6
Jackson, E.K.7
-
35
-
-
0028026693
-
-
Sartorius CA, Groshong SD, Miller LA, Powell RL, Tung L, Takimoto GS, Horwitz KB (1994) "New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP". Cancer Res, 15; 54(14): 3868-77.
-
-
-
-
36
-
-
27544510660
-
Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75
-
Carvajal A, Espinoza N, Kato S, Pinto M, Sadarangani A, Monso C, Aranda E, Villalon M, Richer JK, Horwitz KB, Brosens JJ, Owen GI (2005) Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75. Breast Cancer Res Treat 94(2): 171-183.
-
(2005)
Breast Cancer Res Treat
, vol.94
, Issue.2
, pp. 171-183
-
-
Carvajal, A.1
Espinoza, N.2
Kato, S.3
Pinto, M.4
Sadarangani, A.5
Monso, C.6
Aranda, E.7
Villalon, M.8
Richer, J.K.9
Horwitz, K.B.10
Brosens, J.J.11
Owen, G.I.12
-
37
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9(9): 726-735.
-
(1995)
FASEB J
, vol.9
, Issue.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
38
-
-
0033305372
-
Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals
-
Lange CA, Richer JK, Horwitz KB (1999) Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals. Mol Endocrinol 13(6): 829-836.
-
(1999)
Mol Endocrinol
, vol.13
, Issue.6
, pp. 829-836
-
-
Lange, C.A.1
Richer, J.K.2
Horwitz, K.B.3
-
39
-
-
10044257416
-
Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2
-
Pierson-Mullany LK, Lange CA (2004) Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol 24(24): 10542-10557.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.24
, pp. 10542-10557
-
-
Pierson-Mullany, L.K.1
Lange, C.A.2
-
40
-
-
73349137944
-
A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line
-
Aranda E, Owen GI (2009) A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA. hy926 endothelial cell line. Biol Res 42: 377-389.
-
(2009)
Biol Res
, vol.42
, pp. 377-389
-
-
Aranda, E.1
Owen, G.I.2
-
41
-
-
77950224904
-
In vitro effects of 2-methoxyestradiol on morphology, cell cycle progression, cell death and gene expression changes in the tumorigenic MCF-7 breast epithelial cell line
-
Stander BA, Marais S, Vorster CJ, Joubert AM (2010) In vitro effects of 2-methoxyestradiol on morphology, cell cycle progression, cell death and gene expression changes in the tumorigenic MCF-7 breast epithelial cell line. J Steroid Biochem Mol Biol 119(3-5): 149-160.
-
(2010)
J Steroid Biochem Mol Biol
, vol.119
, Issue.3-5
, pp. 149-160
-
-
Stander, B.A.1
Marais, S.2
Vorster, C.J.3
Joubert, A.M.4
-
42
-
-
58849135484
-
Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells
-
Fukui M, Zhu B-T (2009) Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells. Mol Carcinog 48: 66-78.
-
(2009)
Mol Carcinog
, vol.48
, pp. 66-78
-
-
Fukui, M.1
Zhu, B.-T.2
-
43
-
-
31544434859
-
The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells
-
Newman SP, Ireson CR, Tutill HJ, Day JM, Parsons MF, Leese MP, Potter BV, Reed MJ, Purohit A (2006) The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells. Cancer Res 66(1): 324-330.
-
(2006)
Cancer Res
, vol.66
, Issue.1
, pp. 324-330
-
-
Newman, S.P.1
Ireson, C.R.2
Tutill, H.J.3
Day, J.M.4
Parsons, M.F.5
Leese, M.P.6
Potter, B.V.7
Reed, M.J.8
Purohit, A.9
-
44
-
-
77955555066
-
-
Ting CM, Lee YM, Wong CK, Wong AS, Lung HL, Lung ML, Lo KW, Wong RN, Mak NK. "2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways". Biochem Pharmacol. 2009 Oct 31.
-
-
-
-
45
-
-
33645462175
-
2-methoxyestradiol induces apoptosis in cultured human anaplastic thyroid carcinoma cells
-
Roswall P, Bu S, Rubin K, Landström M, Heldin NE (2006) 2-methoxyestradiol induces apoptosis in cultured human anaplastic thyroid carcinoma cells. Thyroid 16(2): 143-150.
-
(2006)
Thyroid
, vol.16
, Issue.2
, pp. 143-150
-
-
Roswall, P.1
Bu, S.2
Rubin, K.3
Landström, M.4
Heldin, N.E.5
-
46
-
-
33645222234
-
Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways
-
Ray G, Dhar G, van Veldhuizen PJ, Banerjee S, Saxena NK, Sengupta K, Banerjee SK (2006) Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways. Biochemistry 45(11): 3703-3713.
-
(2006)
Biochemistry
, vol.45
, Issue.11
, pp. 3703-3713
-
-
Ray, G.1
Dhar, G.2
van Veldhuizen, P.J.3
Banerjee, S.4
Saxena, N.K.5
Sengupta, K.6
Banerjee, S.K.7
-
47
-
-
48949087080
-
ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma (HCC) cells, and inhibits growth and vascularization in vivo
-
Moser C, Lang SA, Mori A, Hellerbrand C, Schlitt HJ, Geissler EK, Fogler WE, Stoeltzing O (2008) ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma (HCC) cells, and inhibits growth and vascularization in vivo. BMC Cancer 8: 206.
-
(2008)
BMC Cancer
, vol.8
, pp. 206
-
-
Moser, C.1
Lang, S.A.2
Mori, A.3
Hellerbrand, C.4
Schlitt, H.J.5
Geissler, E.K.6
Fogler, W.E.7
Stoeltzing, O.8
-
48
-
-
49749142056
-
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis
-
Kar S, Wang M, Carr BI (2008) 2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis. Cancer Chemother Pharmacol 62(5): 831-840.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, Issue.5
, pp. 831-840
-
-
Kar, S.1
Wang, M.2
Carr, B.I.3
-
49
-
-
70350215541
-
Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells
-
Salama SA, Kamel MW, Botting S, Salih SM, Borahay MA, Hamed AA, Kilic GS, Saeed M, Williams MY, Diaz-Arrastia CR (2009) Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells. PLoS ONE 4(10): e7356.
-
(2009)
PLoS ONE
, vol.4
, Issue.10
-
-
Salama, S.A.1
Kamel, M.W.2
Botting, S.3
Salih, S.M.4
Borahay, M.A.5
Hamed, A.A.6
Kilic, G.S.7
Saeed, M.8
Williams, M.Y.9
Diaz-Arrastia, C.R.10
-
50
-
-
41649119043
-
Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors
-
Faivre EJ, Daniel AR, Hillard CJ, Lange CA (2008) Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol Endocrinol 22(4): 823-837.
-
(2008)
Mol Endocrinol
, vol.22
, Issue.4
, pp. 823-837
-
-
Faivre, E.J.1
Daniel, A.R.2
Hillard, C.J.3
Lange, C.A.4
-
51
-
-
0020626267
-
Concentrations of 2-methoxyoestrogens in human serum measured by a heterologous immunoassay with an 125I-labelled ligand
-
Berg D, Sonsalla R, Kuss E (1983) Concentrations of 2-methoxyoestrogens in human serum measured by a heterologous immunoassay with an 125I-labelled ligand. Acta Endocrinol (Copenh) 103(2): 282-288.
-
(1983)
Acta Endocrinol (Copenh)
, vol.103
, Issue.2
, pp. 282-288
-
-
Berg, D.1
Sonsalla, R.2
Kuss, E.3
|