Prevalence of undiagnosed advanced atrophic corpus gastritis in Finland: An observational study among 4,256 volunteers without specific complaints

Scandinavian Journal of Gastroenterology

Volumn 45, Issue 9, 2010, Pages 1036-1041

  Telaranta Keerie, Aino ^a   Kara, Ritva ^a   Paloheimo, Lea ^a   Hrknen, Matti ^b   Sipponen, Pentti ^c  

^a Biohit Oyj   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c Repolar Oy   (Finland)

Author keywords

Atrophic; Biomarker; Corpus; Fingerprick; Gastritis; GER; Helicobacter pylori; PPI; vitamin B12

Indexed keywords

CYANOCOBALAMIN; IMMUNOGLOBULIN G; PEPSINOGEN I; PEPSINOGEN II; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; ATROPHIC GASTRITIS; FEMALE; FINLAND; GASTROESOPHAGEAL REFLUX; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PLASMA; PREVALENCE; PRIORITY JOURNAL; SCREENING TEST;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; FEASIBILITY STUDIES; FEMALE; FINLAND; GASTRITIS, ATROPHIC; HUMANS; MALE; MIDDLE AGED; PREVALENCE;

EID: 77955539910     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2010.487918     Document Type: Article

References (27)

1. Färkkilä M. Miten dyspepsiaa tulisi hoitaa? Duodecim 2004;120:2537-2542
2. Salaspuro M. Ovatko "testaa ja hoida"-strategian haitat hyötyä suuremmat? Duodecim 2005;121:852.
3. Correa P. Helicobacter pylori and gastric carcinogenesis. Am J Surg Pathol 1995;19(Suppl 1):S37-43.
4. Valle J, Kekki M, Sipponen P, Ihamäki T, Siurala M. Longterm course and consequences of Helicobacter pylori gastritis. Results of a 32-year follow-up study. Scand J Gastroenterol 1996;31:546-550
5. Kekki M, Siurala M, Varis K, Sipponen P, Sistonen P, Nevanlinna HR. Classification principles and genetics of chronic gastritis. Scand J Gastroenterol 1987;141 (Suppl):1-28.
6. Aromaa A, Kosunen TU, Knekt P, Maatela J, Teppo L, Heinonen OP, et al. Circulating anti-Helicobacter pylori immunoglobulin A antibodies and low serum pepsinogen I level are associated with increased risk of gastric cancer. Am J Epidemiol 1996;144:142-149
7. Kokkola A, Kosunen TU, Puolakkainen P, Sipponen P, Harkonen M, Laxen F, et al. Spontaneous disappearance of Helicobacter pylori antibodies in patients with advanced atrophic corpus gastritis. APMIS 2003;111:619-624
8. Kokkola A, Rautelin H, Puolakkainen P, Sipponen P, Färkkilä M, Haapiainen R, et al. Diagnosis of Helicobacter pylori infection in patients with atrophic gastritis: comparison of histology, 13C-urea breath test, and serology. Scand J Gastroenterol 2000;35:138-141
9. Gatta L, Vakil N, Ricci C, Osborn JF, Tampieri A, Perna F, et al. Effect of proton pump inhibitors and antacid therapy on 13C urea breath test and stool test for Helicobacter pylori infection. Am J Gastroenterol 2004;99:823-829
10. Graham DY, Opekun AR, Hammoud F, Yamaoka Y, Reddy R, Osato MS, El-Zimaity HM. Studies regarding the mechanism of false negative urea breath tests with proton pump inhibitors. Am J Gastroenterol 2003;98:1005-1009
11. Correa P, Haenszel W, Cuello C, Zavala D, Fontham E, Zarama G, et al. Gastric precancerous process in a high risk population: cohort follow-up. Cancer Res 1990;50:4737-4740 (Pubitemid 20230422)
12. Sipponen P, Kekki M, Haapakoski J, Ihamäki T, Siurala M. Gastric cancer risk in chronic atrophic gastritis: statistical calculations of cross-sectional data. Int J Cancer 1985; 35:173-177
13. Sipponen P, Graham DY. Importance of atrophic gastritis in diagnostics and prevention of gastric cancer: application of plasma biomarkers. Scand J Gastroenterol 2007;42:2-10.
14. Heikkinen M, Pikkarainen P, Eskelinen M, Julkunen R. GPs ability to diagnose dyspepsia based only on physical examination and patient history. Scand J Prim Health Care 2000;18:99-104.
15. Di Mario F, Cavallaro LG, Moussa AM, Caruana P, Merli R, Maini A, et al. Usefulness of serum pepsinogens in Helicobacter pylori chronic gastritis: relationship with inflammation, activity, and density of the bacterium. Dig Dis Sci 2006;51(10):1791-1795
16. Väänänen H, Vauhkonen M, Helske T, Kääriä inen I, Rasmussen M, Tunturi-Hihnala H, et al. Non-endoscopic diagnosis of atrophic gastritis with a blood test. Correlation between gastric histology and serum levels of gastrin-17 and pepsinogen I: a multicentre study. Eur J Gastroenterol Hepatol 2003;15:885-891
17. Dinis-Ribeiro M, Yamaki G, Miki K, Costa-Pereira A, Matsukawa M, Kurihara M. Meta-analysis on the validity of pepsinogen test for gastric carcinoma, dysplasia or chronic atrophic gastritis screening. J Med Screen 2004;11:141-147
18. Storskrubb T, Aro P, Ronkainen J, Sipponen P, Nyhlin H, Talley NJ, et al. Serum biomarkers provide an accurate method for diagnosis of atrophic gastritis in a general population: the Kalixanda study. Scand J Gastroenterol 2008;43:1448-1455
19. Varis K, Isokoski M. Screening of type A gastritis. Ann Clin Res 1981;13:133-138
20. Loikas S, Koskinen P, Irjala K, Löppönen M, Isoaho R, Kivelä SL, et al. Vitamin B12 deficiency in the aged: a population-based study. Age Aging 2007;36:177-183
21. Sipponen P, Laxen F, Huotari K, Härkönen M. Prevalence of low vitamin B12 and high homocysteine in serum in an elderly male population: association with atrophic gastritis and Helicobacter pylori infection. Scand J Gastroenterol 2003;38:1209-1216
22. Malfertheiner P, Mégraud F, OMorain C, Bazzoli F, El-Omar E, Graham D, et al. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 2007;56:772-781 (Pubitemid 46854190)
23. Väkeväinen S, Mentula S, Nuutinen H, Salmela KS, Jousimies-Somer H, Färkkilä M, et al. Ethanol-derived microbial production of carcinogenic acetaldehyde in achlorhydric atrophic gastritis. Scand J Gastroenterol 2002;37: 648-655
24. Martinsen TC, Bergh K, Waldum HL. Gastric juice: a barrier against infectious diseases. Basic Clin Pharmacol Toxicol 2005;96:94-102.
25. Sipponen P, HärkönenM. Hypochlorhydric stomach-a risk condition for calcium malabsorption and osteoporosis? Scand J Gastroenterol 2010:45:133-138
26. Sipponen P, Varis K, Fräki O, Korri UM, Seppälä K, Siurala M. Cumulative 10-year risk of symptomatic duodenal and gastric ulcer in patients with or without chronic gastritis. A clinical follow-up study of 454 outpatients. Scand J Gastroenterol 1990;25:966-973
27. Sipponen P, Seppälä K, Ä;ärynen M, Helske T, Kettunen P. Chronic gastritis and gastroduodenal ulcer: a case control study on risk of coexisting duodenal or gastric ulcer in patients with gastritis. Gut 1989;30:922-929