The Drug Discovery Portal: A resource to enhance drug discovery from academia

Drug Discovery Today

Volumn 15, Issue 15-16, 2010, Pages 679-683

  Clark, Rachel L ^a   Johnston, Blair F ^a   Mackay, Simon P ^a   Breslin, Catherine J ^a   Robertson, Murray N ^a   Harvey, Alan L ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; COMMERCIAL PHENOMENA; COMPUTER PROGRAM; CONFORMATIONAL TRANSITION; DATA BASE; DISTRIBUTION VOLUME; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG MECHANISM; DRUG TARGETING; FUNDING; HIGH THROUGHPUT SCREENING; HUMAN; LIGAND BINDING; LIPOPHILICITY; MOLECULAR LIBRARY; PRINCIPAL COMPONENT ANALYSIS; PROCESS OPTIMIZATION; PROGRAM DEVELOPMENT; QUALITY CONTROL; REVIEW; RUSSIAN FEDERATION; SWEDEN; SYNTHESIS; UNITED KINGDOM; UNITED STATES; UNIVERSITY;

CHEMISTRY, PHARMACEUTICAL; COOPERATIVE BEHAVIOR; DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG DISCOVERY; DRUG INDUSTRY; PHARMACEUTICAL PREPARATIONS; RESEARCH; SCOTLAND; UNIVERSITIES;

EID: 77955515111     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2010.06.003     Document Type: Review

References (16)

1. Glicksman M. The drug discovery process in academics. Opportunity knocks. BIOForum Europe 2008, 6:34-35.
2. Shah S. Drug discovery dilemma and Cura Quartet collaboration. Drug Discov. Today 2009, 14:1006-1010.
3. Glaser K.B., Mayer A.M.S. A renaissance in marine pharmacology: from preclinical curiosity to clinical reality. Biochem. Pharmacol. 2009, 78:440-448.
4. Frearson J.A., Collie I.A. HTS and hit finding in academia - from chemical genomics to drug discovery. Drug Discov. Today 2009, 14:1150-1158.
5. Tralau-Stewart C.J., et al. Drug discovery: new models for industry-academic partnerships. Drug Discov. Today 2009, 14:95-101.
6. Hughes B. Pharma pursues novel models for academic collaboration. Nat. Rev. Drug Discov. 2008, 7:631-632.
7. Kozikowski A.P., et al. Why academic drug discovery makes sense. Science 2006, 313:1235-1236.
8. Simeonov A., et al. Fluorescence spectroscopic profiling of compound libraries. J. Med. Chem. 2008, 51:2363-2371.
9. Hergenrother P.J. Obtaining and screening compound collections: a user's guide and a call to chemists. Curr. Opin. Chem. Biol. 2006, 10:213-218.
10. Hibert M.F. French/European academic compound library initiative. Drug Discov. Today 2009, 14:723-725.
11. Phatak S.S., et al. High-throughput and in silico screenings in drug discovery. Expert Opin. Drug Discov. 2009, 4:947-959.
12. Harvey A.L. Natural products as a screening resource. Curr. Opin. Chem. Biol. 2007, 11:480-484.
13. Harvey A.L. Natural products in drug discovery. Drug Discov. Today 2008, 13:894-901.
14. Lipinski C.A., et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 2001, 46:3-26.
15. Ghosh S., et al. Structure-based virtual screening of chemical libraries for drug discovery. Curr. Opin. Chem. Biol. 2006, 10:194-202.
16. Talaga P. Open innovation: share or die.... Drug Discov. Today 2009, 14:1003-1005.