Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease

Gastroenterology

Volumn 139, Issue 2, 2010, Pages 430-438

  Thayu, Meena ^a,b   Denson, Lee A ^c   Shults, Justine ^b   Zemel, Babette S ^a   Burnham, Jon M ^a,b   Baldassano, Robert N ^a   Howard, Krista M ^a   Ryan, Anne ^c   Leonard, Mary B ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Children; Crohn's Disease; Growth; Nutrition

Indexed keywords

ALBUMIN; AZATHIOPRINE; GLUCOCORTICOID; GROWTH FACTOR; GROWTH HORMONE BINDING PROTEIN; INFLIXIMAB; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MERCAPTOPURINE; METHOTREXATE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; CYTOKINE; GASTROINTESTINAL AGENT; SIGNAL PEPTIDE;

ADOLESCENT; ADULT; ANTHROPOMETRY; ARTICLE; BLOOD LEVEL; BODY COMPOSITION; BODY FAT DISTRIBUTION; BODY MASS; CACHEXIA; CHILD; CHILD GROWTH; CLINICAL ASSESSMENT; CONTROLLED STUDY; CROHN DISEASE; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE COURSE; DUAL ENERGY X RAY ABSORPTIOMETRY; ENTERAL FEEDING PUMP; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GROWTH CURVE; GROWTH DISORDER; HEIGHT; HEMATOCRIT; HUMAN; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PUBERTY; AGE; AGING; BLOOD; BODY HEIGHT; CASE CONTROL STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; INCIDENCE; PATHOPHYSIOLOGY; PHOTON ABSORPTIOMETRY; PRESCHOOL CHILD; REGRESSION ANALYSIS; TREATMENT OUTCOME; UNITED STATES;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; AGE FACTORS; AGING; ANTHROPOMETRY; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; BODY COMPOSITION; BODY HEIGHT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROHN DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; INCIDENCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEAST-SQUARES ANALYSIS; MALE; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 77955501954     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.04.044     Document Type: Article

References (50)

1. R. Roubenoff, and J.J. Kehayias The meaning and measurement of lean body mass Nutr Rev 49 1991 163 175
2. E. Schonau, E. Werhahn, U. Schiedermaier, et al. Influence of muscle strength on bone strength during childhood and adolescence Horm Res 45 Suppl 1 1996 63 66
3. A.M. Boot, J. Bouquet, E.P. Krenning, et al. Bone mineral density and nutritional status in children with chronic inflammatory bowel disease Gut 42 1998 188 194
4. E. Capristo, G. Addolorato, G. Mingrone, et al. Effect of disease localization on the anthropometric and metabolic features of Crohn's disease Am J Gastroenterol 93 1998 2411 2419
5. E. Capristo, G. Mingrone, G. Addolorato, et al. Metabolic features of inflammatory bowel disease in a remission phase of the disease activity J Intern Med 243 1998 339 347
6. G. Mingrone, G. Benedetti, E. Capristo, et al. Twenty-four-hour energy balance in Crohn disease patients: metabolic implications of steroid treatment Am J Clin Nutr 67 1998 118 123
7. K.V. Haderslev, P.B. Jeppesen, H.A. Sorensen, et al. Body composition measured by dual-energy x-ray absorptiometry in patients who have undergone small-intestinal resection Am J Clin Nutr 78 2003 78 83
8. M. Azcue, M. Rashid, A. Griffiths, et al. Energy expenditure and body composition in children with Crohn's disease: effect of enteral nutrition and treatment with prednisolone Gut 41 1997 203 208
9. J. Jahnsen, J.A. Falch, P. Mowinckel, et al. Body composition in patients with inflammatory bowel disease: a population-based study Am J Gastroenterol 98 2003 1556 1562
10. B.J. Geerling, W.D. Lichtenbelt, R.W. Stockbrugger, et al. Gender specific alterations of body composition in patients with inflammatory bowel disease compared with controls Eur J Clin Nutr 53 1999 479 485
11. B. Schneeweiss, H. Lochs, C. Zauner, et al. Energy and substrate metabolism in patients with active Crohn's disease J Nutr 129 1999 844 848
12. R. Rocha, G.O. Santana, N. Almeida, et al. Analysis of fat and muscle mass in patients with inflammatory bowel disease during remission and active phase Br J Nutr 101 2009 676 679
13. N. Lee, G.L. Radford-Smith, M. Forwood, et al. Body composition and muscle strength as predictors of bone mineral density in Crohn's disease J Bone Miner Metab 27 2009 456 463
14. S.M. Schneider, R. Al-Jaouni, J. Filippi, et al. Sarcopenia is prevalent in patients with Crohn's disease in clinical remission Inflamm Bowel Dis 14 2008 1562 1568
15. J.M. Burnham, J. Shults, E. Semeao, et al. Whole body BMC in pediatric Crohn disease: independent effects of altered growth, maturation, and body composition J Bone Miner Res 19 2004 1961 1968
16. J.M. Burnham, J. Shults, E. Semeao, et al. Body-composition alterations consistent with cachexia in children and young adults with Crohn disease Am J Clin Nutr 82 2005 413 420
17. R. Roubenoff, R.A. Roubenoff, L.M. Ward, et al. Rheumatoid cachexia: depletion of lean body mass in rheumatoid arthritis Possible association with tumor necrosis factor J Rheumatol 19 1992 1505 1510
18. L.C. Rall, and R. Roubenoff Rheumatoid cachexia: metabolic abnormalities, mechanisms and interventions Rheumatology (Oxford) 43 2004 1219 1223
19. M. Thayu, J. Shults, J.M. Burnham, et al. Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's disease Inflamm Bowel Dis 13 2007 1121 1128
20. F.A. Sylvester, S. Leopold, M. Lincoln, et al. A two-year longitudinal study of persistent lean tissue deficits in children with Crohn's disease Clin Gastroenterol Hepatol 7 2009 452 455
21. S.E. Dubner, J. Shults, R.N. Baldassano, et al. Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease Gastroenterology 136 2009 123 130
22. J. Satsangi, M.S. Silverberg, S. Vermeire, et al. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications Gut 55 2006 749 753
23. J.S. Hyams, G.D. Ferry, F.S. Mandel, et al. Development and validation of a pediatric Crohn's disease activity index J Pediatr Gastroenterol Nutr 12 1991 439 447
24. N.N. Morris, and J.R. Udry Validation of a self-administered instrument to assess stage of adolescent development J Youth Adolesc 1980 271 280
25. J.M. Tanner Growth at Adolescence 1962 Blackwell Scientific Publication Hobokon, NJ
26. B.J. Foster, J. Shults, B.S. Zemel, et al. Interactions between growth and body composition in children treated with high-dose chronic glucocorticoids Am J Clin Nutr 80 2004 1334 1341
27. K.J. Ellis, R.J. Shypailo, S.A. Abrams, et al. The reference child and adolescent models of body composition A contemporary comparison Ann N Y Acad Sci 904 2000 374 382
28. K.J. Ellis Body composition of a young, multiethnic, male population Am J Clin Nutr 66 1997 1323 1331
29. A. Goulding, R.W. Taylor, and E. Gold Regional body fat distribution in relation to pubertal stage: a dual-energy x-ray absorptiometry study of New Zealand girls and young women Am J Clin Nutr 64 1996 546 551 (Pubitemid 26334232)
30. G.D. Ogle, J.R. Allen, I.R. Humphries, et al. Body-composition assessment by dual-energy x-ray absorptiometry in subjects aged 4-26 y Am J Clin Nutr 61 1995 746 753
31. T. Lloyd, V.M. Chinchilli, D.F. Eggli, et al. Body composition development of adolescent white females: the Penn State Young Women's Health Study Arch Pediatr Adolesc Med 152 1998 998 1002
32. C.L. Ogden, R.J. Kuczmarski, K.M. Flegal, et al. Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version Pediatrics 109 2002 45 60
33. T.J. Cole The LMS method for constructing normalized growth standards Eur J Clin Nutr 44 1990 45 60
34. J. Shults, S.J. Ratcliffe, and M.B. Leonard Improved generalized estimating equation analysis via xtqls for implementation of quali-least squares in Stata STATA J 7 2007 147 166
35. P.G. Andres, and L.S. Friedman Epidemiology and the natural course of inflammatory bowel disease Gastroenterol Clin North Am 28 1999 255 281 vii
36. M. Pfefferkorn, G. Burke, A. Griffiths, et al. Growth abnormalities persist in newly diagnosed children with Crohn disease despite current treatment paradigms J Pediatr Gastroenterol Nutr 48 2009 168 174
37. T.D. Walters, A.R. Gilman, and A.M. Griffiths Linear growth improves during infliximab therapy in children with chronically active severe Crohn's disease Inflamm Bowel Dis 13 2007 424 430
38. M. Thayu, M.B. Leonard, J.S. Hyams, et al. Improvement in biomarkers of bone formation during infliximab therapy in pediatric Crohn's disease: results of the REACH study Clin Gastroenterol Hepatol 6 2008 1378 1384
39. L. Denson, M. Held, D. Arnold, et al. Interleukin 6 inhibits growth hormone signaling via induction of cis and socs-3 Gastroenterology 122 2002 A42 362
40. A. Sawczenko, O. Azooz, J. Paraszczuk, et al. Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children Proc Natl Acad Sci U S A 102 2005 13260 13265
41. R.C. Langen, A.M. Schols, M.C. Kelders, et al. Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB FASEB J 15 2001 1169 1180
42. R.C. Langen, A.M. Schols, M.C. Kelders, et al. Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways Am J Physiol Cell Physiol 283 2002 C714 C721
43. C.E. Stewart, P.V. Newcomb, and J.M. Holly Multifaceted roles of TNF-alpha in myoblast destruction: a multitude of signal transduction pathways J Cell Physiol 198 2004 237 247
44. B.A. Pasternak, S. D'Mello, I.I. Jurickova, et al. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis Inflamm Bowel Dis 16 2010 856 869
45. C. Ohlsson, S. Mohan, K. Sjogren, et al. The role of liver-derived insulin-like growth factor-I Endocr Rev 30 2009 494 535
46. P. Klover, and L. Hennighausen Postnatal body growth is dependent on the transcription factors signal transducers and activators of transcription 5a/b in muscle: a role for autocrine/paracrine insulin-like growth factor I Endocrinology 148 2007 1489 1497
47. A. Lelbach, J.G. Scharf, and G. Ramadori Regulation of insulin-like growth factor-I and of insulin-like growth factor binding protein-1, -3 and -4 in cocultures of rat hepatocytes and Kupffer cells by interleukin-6 J Hepatol 35 2001 558 567 (Pubitemid 33078264)
48. J. Alele, J. Jiang, J.F. Goldsmith, et al. Blockade of growth hormone receptor shedding by a metalloprotease inhibitor Endocrinology 139 1998 1927 1935
49. S. Fisker, B. Hansen, J. Fuglsang, et al. Gene expression of the GH receptor in subcutaneous and intraabdominal fat in healthy females: relationship to GH-binding protein Eur J Endocrinol 150 2004 773 777
50. X. Wang, J. Jiang, J. Warram, et al. Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: a novel mechanism for GH insensitivity Mol Endocrinol 22 2008 1427 1437