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Volumn 26, Issue 2, 2010, Pages 265-276

Current concepts on the pathophysiology of pasture-associated laminitis

Author keywords

Endotoxemia; Fructans; Hyperinsulinemia; Insulin resistance; Laminitis; Nonstructural carbohydrates; Obesity

Indexed keywords

ANIMAL; ANIMAL DISEASE; ANIMAL HUSBANDRY; FOOT DISEASE; HOOF AND CLAW; HORSE; HORSE DISEASE; INFLAMMATION; PATHOPHYSIOLOGY; REVIEW;

EID: 77955500154     PISSN: 07490739     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cveq.2010.06.001     Document Type: Review
Times cited : (50)

References (44)
  • 1
    • 77950365442 scopus 로고    scopus 로고
    • Overview of current laminitis research
    • Eades S.C. Overview of current laminitis research. Vet Clin North Am Equine Pract 2010, 26:51-63.
    • (2010) Vet Clin North Am Equine Pract , vol.26 , pp. 51-63
    • Eades, S.C.1
  • 2
    • 1142287280 scopus 로고    scopus 로고
    • Current research and theories on the pathogenesis of acute laminitis in the horse
    • Bailey S.R., Marr C.M., Elliott J. Current research and theories on the pathogenesis of acute laminitis in the horse. Vet J 2004, 167:129-142.
    • (2004) Vet J , vol.167 , pp. 129-142
    • Bailey, S.R.1    Marr, C.M.2    Elliott, J.3
  • 3
    • 0007154329 scopus 로고    scopus 로고
    • National Animal Health Monitoring System, Fort Collins (CO)
    • USDA-NAHMS Lameness and laminitis in US horses 2000, National Animal Health Monitoring System, Fort Collins (CO), p. 12.
    • (2000) USDA-NAHMS Lameness and laminitis in US horses , pp. 12
  • 4
    • 77955492054 scopus 로고    scopus 로고
    • The epidemiology of equine laminitis in the UK. In: Proceedings of the 35th Congress of the British Equine Veterinary Association. Warwick (UK)
    • Hinckley K, Henderson I. The epidemiology of equine laminitis in the UK. In: Proceedings of the 35th Congress of the British Equine Veterinary Association. Warwick (UK): 1996. p. 62.
    • (1996) , pp. 62
    • Hinckley, K.1    Henderson, I.2
  • 5
    • 33745302078 scopus 로고    scopus 로고
    • Equine laminitis induced with oligofructose
    • van Eps A.W., Pollitt C.C. Equine laminitis induced with oligofructose. Equine Vet J 2006, 38:203-208.
    • (2006) Equine Vet J , vol.38 , pp. 203-208
    • van Eps, A.W.1    Pollitt, C.C.2
  • 6
    • 33646589602 scopus 로고    scopus 로고
    • Evaluation of genetic and metabolic predispositions and nutritional risk factors for pasture-associated laminitis in ponies
    • Treiber K.H., Kronfeld D.S., Hess T.M., et al. Evaluation of genetic and metabolic predispositions and nutritional risk factors for pasture-associated laminitis in ponies. J Am Vet Med Assoc 2006, 228:1538-1545.
    • (2006) J Am Vet Med Assoc , vol.228 , pp. 1538-1545
    • Treiber, K.H.1    Kronfeld, D.S.2    Hess, T.M.3
  • 7
    • 0942284826 scopus 로고    scopus 로고
    • The equine metabolic syndrome: peripheral Cushing's syndrome
    • Johnson P.J. The equine metabolic syndrome: peripheral Cushing's syndrome. Vet Clin North Am Equine Pract 2002, 18:271-293.
    • (2002) Vet Clin North Am Equine Pract , vol.18 , pp. 271-293
    • Johnson, P.J.1
  • 8
    • 64749109220 scopus 로고    scopus 로고
    • Metabolic syndrome - from human organ disease to laminar failure in equids
    • Geor R., Frank N. Metabolic syndrome - from human organ disease to laminar failure in equids. Vet Immunol Immunopathol 2009, 129:151-154.
    • (2009) Vet Immunol Immunopathol , vol.129 , pp. 151-154
    • Geor, R.1    Frank, N.2
  • 9
    • 33646230549 scopus 로고    scopus 로고
    • Physical characteristics, blood hormone concentrations, and plasma lipid concentrations in obese horses with insulin resistance
    • Frank N., Elliott S.B., Brandt L.E., et al. Physical characteristics, blood hormone concentrations, and plasma lipid concentrations in obese horses with insulin resistance. J Am Vet Med Assoc 2006, 228:1383-1390.
    • (2006) J Am Vet Med Assoc , vol.228 , pp. 1383-1390
    • Frank, N.1    Elliott, S.B.2    Brandt, L.E.3
  • 10
    • 36049009365 scopus 로고    scopus 로고
    • Induction of laminitis by prolonged hyperinsulinaemia in clinically normal ponies
    • Asplin K.E., Sillence M.N., Pollitt C.C., et al. Induction of laminitis by prolonged hyperinsulinaemia in clinically normal ponies. Vet J 2007, 174:530-535.
    • (2007) Vet J , vol.174 , pp. 530-535
    • Asplin, K.E.1    Sillence, M.N.2    Pollitt, C.C.3
  • 11
    • 77049104525 scopus 로고    scopus 로고
    • Equine laminitis: induced by 48 h hyperinsulinaemia in Standardbred horses
    • De Laat M.A., McGowan C.M., Sillence M.N., et al. Equine laminitis: induced by 48 h hyperinsulinaemia in Standardbred horses. Equine Vet J 2010, 42:129-135.
    • (2010) Equine Vet J , vol.42 , pp. 129-135
    • De Laat, M.A.1    McGowan, C.M.2    Sillence, M.N.3
  • 12
    • 77955481773 scopus 로고    scopus 로고
    • The prevalence of laminitis in one region of the UK. In: 40th British Equine Veterinary Association Congress
    • Katz L, DeBrauwere N, Elliott J, et al. The prevalence of laminitis in one region of the UK. In: 40th British Equine Veterinary Association Congress. 2001. p. 199.
    • (2001) , pp. 199
    • Katz, L.1    DeBrauwere, N.2    Elliott, J.3
  • 13
    • 65549140514 scopus 로고    scopus 로고
    • Prediction of incipient pasture-associated laminitis from hyperinsulinemia, hyperleptinemia and generalized and localized obesity in a cohort of ponies
    • Carter R.A., Treiber K.H., Geor R.J., et al. Prediction of incipient pasture-associated laminitis from hyperinsulinemia, hyperleptinemia and generalized and localized obesity in a cohort of ponies. Equine Vet J 2009, 40:171-178.
    • (2009) Equine Vet J , vol.40 , pp. 171-178
    • Carter, R.A.1    Treiber, K.H.2    Geor, R.J.3
  • 14
    • 38749117538 scopus 로고    scopus 로고
    • Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis
    • Bailey S.R., Habershon-Butcher J.L., Ransom K.J., et al. Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis. Am J Vet Res 2008, 69:122-129.
    • (2008) Am J Vet Res , vol.69 , pp. 122-129
    • Bailey, S.R.1    Habershon-Butcher, J.L.2    Ransom, K.J.3
  • 16
    • 0141990576 scopus 로고    scopus 로고
    • Determination of reference range values indicative of glucose metabolism and insulin resistance by use of glucose clamp techniques in horses and ponies
    • Rijnen K.E., van der Kolk J.H. Determination of reference range values indicative of glucose metabolism and insulin resistance by use of glucose clamp techniques in horses and ponies. Am J Vet Res 2003, 64:1260-1264.
    • (2003) Am J Vet Res , vol.64 , pp. 1260-1264
    • Rijnen, K.E.1    van der Kolk, J.H.2
  • 17
    • 1642441793 scopus 로고    scopus 로고
    • Evaluation of suspected pituitary pars intermedia dysfunction in horses with laminitis
    • Donaldson M.T., Jorgensen A.J., Beech J. Evaluation of suspected pituitary pars intermedia dysfunction in horses with laminitis. J Am Vet Med Assoc 2004, 224:1123-1127.
    • (2004) J Am Vet Med Assoc , vol.224 , pp. 1123-1127
    • Donaldson, M.T.1    Jorgensen, A.J.2    Beech, J.3
  • 18
    • 29244465117 scopus 로고    scopus 로고
    • Fat as an endocrine organ: relationship to the metabolic syndrome
    • Hutley L., Prins J.B. Fat as an endocrine organ: relationship to the metabolic syndrome. Am J Med Sci 2005, 330:280-289.
    • (2005) Am J Med Sci , vol.330 , pp. 280-289
    • Hutley, L.1    Prins, J.B.2
  • 19
    • 33750951234 scopus 로고    scopus 로고
    • ABC of obesity: risk factors for diabetes and coronary heart disease
    • Wild S.H., Byrne C.D. ABC of obesity: risk factors for diabetes and coronary heart disease. Br Med J 2006, 333:1009-1011.
    • (2006) Br Med J , vol.333 , pp. 1009-1011
    • Wild, S.H.1    Byrne, C.D.2
  • 20
    • 34247872834 scopus 로고    scopus 로고
    • Relationships among inflammatory cytokines, obesity and insulin sensitivity in the horse
    • Vick M.M., Adams A.A., Murphy B.A., et al. Relationships among inflammatory cytokines, obesity and insulin sensitivity in the horse. J Anim Sci 2007, 85:1144-1155.
    • (2007) J Anim Sci , vol.85 , pp. 1144-1155
    • Vick, M.M.1    Adams, A.A.2    Murphy, B.A.3
  • 21
    • 33745665806 scopus 로고    scopus 로고
    • Pasture nonstructural carbohydrates and equine laminitis
    • 2099S-102S
    • Longland A.C., Byrd B.M. Pasture nonstructural carbohydrates and equine laminitis. J Nutr 2006, 136(Suppl 7). 2099S-102S.
    • (2006) J Nutr , vol.136 , Issue.SUPPL 7
    • Longland, A.C.1    Byrd, B.M.2
  • 23
    • 77950353747 scopus 로고    scopus 로고
    • Microbial events in the hindgut during carbohydrate-induced equine laminitis
    • Milinovich G.J., Klieve A.V., Pollitt C.C., et al. Microbial events in the hindgut during carbohydrate-induced equine laminitis. Vet Clin North Am Equine Pract 2010, 26:79-94.
    • (2010) Vet Clin North Am Equine Pract , vol.26 , pp. 79-94
    • Milinovich, G.J.1    Klieve, A.V.2    Pollitt, C.C.3
  • 24
    • 33645452982 scopus 로고    scopus 로고
    • Changes in equine hindgut bacterial populations during oligofructose-induced laminitis
    • Milinovich G.J., Trott D.J., Burrell P.C., et al. Changes in equine hindgut bacterial populations during oligofructose-induced laminitis. Environ Microbiol 2006, 8:885-898.
    • (2006) Environ Microbiol , vol.8 , pp. 885-898
    • Milinovich, G.J.1    Trott, D.J.2    Burrell, P.C.3
  • 25
    • 33745659861 scopus 로고    scopus 로고
    • Gastrointestinal derived factors are potential triggers for the development of acute equine laminitis
    • 2103S-7S
    • Elliott J., Bailey S.R. Gastrointestinal derived factors are potential triggers for the development of acute equine laminitis. J Nutr 2006, 136. 2103S-7S.
    • (2006) J Nutr , vol.136
    • Elliott, J.1    Bailey, S.R.2
  • 26
    • 64749088636 scopus 로고    scopus 로고
    • Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis
    • Bailey S.R., Adair H.S., Reinemeyer C.R., et al. Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. Vet Immunol Immunopathol 2009, 129:167-173.
    • (2009) Vet Immunol Immunopathol , vol.129 , pp. 167-173
    • Bailey, S.R.1    Adair, H.S.2    Reinemeyer, C.R.3
  • 27
    • 2542528573 scopus 로고    scopus 로고
    • Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators
    • Menzies-Gow N.J., Bailey S.R., Katz L.M., et al. Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. Equine Vet J 2004, 36:273-278.
    • (2004) Equine Vet J , vol.36 , pp. 273-278
    • Menzies-Gow, N.J.1    Bailey, S.R.2    Katz, L.M.3
  • 28
    • 77951929905 scopus 로고    scopus 로고
    • Effects of endotoxaemia and carbohydrate overload on glucose and insulin dynamics and the development of laminitis in horses
    • Toth F., Frank N., Chameroy K.A., et al. Effects of endotoxaemia and carbohydrate overload on glucose and insulin dynamics and the development of laminitis in horses. Equine Vet J 2009, 41:852-858.
    • (2009) Equine Vet J , vol.41 , pp. 852-858
    • Toth, F.1    Frank, N.2    Chameroy, K.A.3
  • 29
    • 33947362819 scopus 로고    scopus 로고
    • Risk factors for development of acute laminitis in horses during hospitalization: 73 cases (1997-2004)
    • Parsons C.S., Orsini J.A., Krafty R., et al. Risk factors for development of acute laminitis in horses during hospitalization: 73 cases (1997-2004). J Am Vet Med Assoc 2007, 230:885-889.
    • (2007) J Am Vet Med Assoc , vol.230 , pp. 885-889
    • Parsons, C.S.1    Orsini, J.A.2    Krafty, R.3
  • 30
    • 33846507990 scopus 로고    scopus 로고
    • Serial alterations in digital hemodynamics and endothelin-1 immunoreactivity, platelet-neutrophil aggregation, and concentrations of nitric oxide, insulin and glucose in blood obtained from horses following carbohydrate overload
    • Eades S.C., Stokes A.M., Johnson P.J., et al. Serial alterations in digital hemodynamics and endothelin-1 immunoreactivity, platelet-neutrophil aggregation, and concentrations of nitric oxide, insulin and glucose in blood obtained from horses following carbohydrate overload. Am J Vet Res 2007, 68:87-94.
    • (2007) Am J Vet Res , vol.68 , pp. 87-94
    • Eades, S.C.1    Stokes, A.M.2    Johnson, P.J.3
  • 32
    • 0036780537 scopus 로고    scopus 로고
    • Production of amines in equine cecal contents in an in vitro model of carbohydrate overload
    • Bailey S.R., Rycroft A., Elliott J. Production of amines in equine cecal contents in an in vitro model of carbohydrate overload. J Anim Sci 2002, 80:2656-2662.
    • (2002) J Anim Sci , vol.80 , pp. 2656-2662
    • Bailey, S.R.1    Rycroft, A.2    Elliott, J.3
  • 33
    • 34547356588 scopus 로고    scopus 로고
    • Environmental effects on nutritive value of equine pastures in Northern Virginia
    • Cubitt T.A., Staniar W.B., Kronfeld D.S., et al. Environmental effects on nutritive value of equine pastures in Northern Virginia. Pferdeheilkunde 2007, 23:151-154.
    • (2007) Pferdeheilkunde , vol.23 , pp. 151-154
    • Cubitt, T.A.1    Staniar, W.B.2    Kronfeld, D.S.3
  • 34
    • 34547133526 scopus 로고    scopus 로고
    • Circadian and seasonal variation on pasture NSC and circulating insulin concentrations in grazing horses [abstract]
    • Byrd B.M., Treiber K.H., Staniar W.B., et al. Circadian and seasonal variation on pasture NSC and circulating insulin concentrations in grazing horses [abstract]. J Anim Sci 2006, 84(Suppl 1):330-331.
    • (2006) J Anim Sci , vol.84 , Issue.SUPPL 1 , pp. 330-331
    • Byrd, B.M.1    Treiber, K.H.2    Staniar, W.B.3
  • 35
    • 57049134772 scopus 로고    scopus 로고
    • Seasonal changes in energy metabolism of ponies coincides with changes in pasture carbohydrates: implications for laminitis [abstract]
    • Treiber K.H., Carter R.A., Harris P.A., et al. Seasonal changes in energy metabolism of ponies coincides with changes in pasture carbohydrates: implications for laminitis [abstract]. J Vet Intern Med 2008, 22:735-736.
    • (2008) J Vet Intern Med , vol.22 , pp. 735-736
    • Treiber, K.H.1    Carter, R.A.2    Harris, P.A.3
  • 36
    • 36649037243 scopus 로고    scopus 로고
    • Effect of dietary fructan and dexamethasone on the insulin response of ponies predisposed to laminitis
    • Bailey S.R., Menzies-Gow N.J., Harris P.A., et al. Effect of dietary fructan and dexamethasone on the insulin response of ponies predisposed to laminitis. J Am Vet Med Assoc 2007, 231:1365-1373.
    • (2007) J Am Vet Med Assoc , vol.231 , pp. 1365-1373
    • Bailey, S.R.1    Menzies-Gow, N.J.2    Harris, P.A.3
  • 38
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms
    • Kim J.K., Montagnani M., Koh K.K., et al. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 2006, 113:1888-1904.
    • (2006) Circulation , vol.113 , pp. 1888-1904
    • Kim, J.K.1    Montagnani, M.2    Koh, K.K.3
  • 39
    • 0032431072 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes mellitus
    • Cosentino F., Luscher T.F. Endothelial dysfunction in diabetes mellitus. J Cardiovasc Pharmacol 1998, 32(3):S54-S61.
    • (1998) J Cardiovasc Pharmacol , vol.32 , Issue.3
    • Cosentino, F.1    Luscher, T.F.2
  • 40
    • 34447303780 scopus 로고    scopus 로고
    • Inflammatory responses underlying the microvascular dysfunction associated with obesity and insulin resistance
    • Singer G., Granger D.N. Inflammatory responses underlying the microvascular dysfunction associated with obesity and insulin resistance. Microcirculation 2007, 14:375-387.
    • (2007) Microcirculation , vol.14 , pp. 375-387
    • Singer, G.1    Granger, D.N.2
  • 41
    • 2542516279 scopus 로고    scopus 로고
    • The effects of vasoactive amines found in the equine hindgut on digital blood flow in the normal horse
    • Bailey S.R., Menzies-Gow N.J., Marr C.M., et al. The effects of vasoactive amines found in the equine hindgut on digital blood flow in the normal horse. Equine Vet J 2004, 36:267-272.
    • (2004) Equine Vet J , vol.36 , pp. 267-272
    • Bailey, S.R.1    Menzies-Gow, N.J.2    Marr, C.M.3
  • 42
    • 0043217848 scopus 로고    scopus 로고
    • Identification and quantification of amines in the equine caecum
    • Bailey S.R., Marr C.M., Elliott J. Identification and quantification of amines in the equine caecum. Res Vet Sci 2003, 74:113-118.
    • (2003) Res Vet Sci , vol.74 , pp. 113-118
    • Bailey, S.R.1    Marr, C.M.2    Elliott, J.3
  • 43
    • 0042232662 scopus 로고    scopus 로고
    • Seasonal changes in plasma concentrations of cecum-derived amines in clinically normal ponies and ponies predisposed to laminitis
    • Bailey S.R., Katz L.M., Berhane Y., et al. Seasonal changes in plasma concentrations of cecum-derived amines in clinically normal ponies and ponies predisposed to laminitis. Am J Vet Res 2003, 64:1132-1138.
    • (2003) Am J Vet Res , vol.64 , pp. 1132-1138
    • Bailey, S.R.1    Katz, L.M.2    Berhane, Y.3
  • 44
    • 36148994729 scopus 로고    scopus 로고
    • Dietary fructan carbohydrate increases amine production in the equine large intestine: implications for pasture-associated laminitis
    • Crawford C., Sepulveda M.F., Elliott J., et al. Dietary fructan carbohydrate increases amine production in the equine large intestine: implications for pasture-associated laminitis. J Anim Sci 2007, 85:2949-2958.
    • (2007) J Anim Sci , vol.85 , pp. 2949-2958
    • Crawford, C.1    Sepulveda, M.F.2    Elliott, J.3


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