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Volumn 20, Issue 15, 2010, Pages 1372-1377

Feedback regulation of ras signaling by rabex-5-mediated ubiquitination

Author keywords

CELLBIO; SIGNALING

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; RABGEF1 PROTEIN, HUMAN; RAS PROTEIN; RIN1 PROTEIN, HUMAN; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE;

EID: 77955496936     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.06.051     Document Type: Article
Times cited : (88)

References (27)
  • 1
    • 33344475413 scopus 로고    scopus 로고
    • Differential modification of Ras proteins by ubiquitination
    • N. Jura, E. Scotto-Lavino, A. Sobczyk, and D. Bar-Sagi Differential modification of Ras proteins by ubiquitination Mol. Cell 21 2006 679 687
    • (2006) Mol. Cell , vol.21 , pp. 679-687
    • Jura, N.1    Scotto-Lavino, E.2    Sobczyk, A.3    Bar-Sagi, D.4
  • 3
    • 4444351852 scopus 로고    scopus 로고
    • Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5
    • A. Delprato, E. Merithew, and D.G. Lambright Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5 Cell 118 2004 607 617
    • (2004) Cell , vol.118 , pp. 607-617
    • Delprato, A.1    Merithew, E.2    Lambright, D.G.3
  • 4
    • 0028859266 scopus 로고
    • A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1
    • L. Han, and J. Colicelli A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1 Mol. Cell. Biol. 15 1995 1318 1323
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1318-1323
    • Han, L.1    Colicelli, J.2
  • 6
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: Different signals from different locations
    • J.F. Hancock Ras proteins: Different signals from different locations Nat. Rev. Mol. Cell Biol. 4 2003 373 384
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 7
    • 33644864788 scopus 로고    scopus 로고
    • Compartmentalized Ras/MAPK signaling
    • A. Mor, and M.R. Philips Compartmentalized Ras/MAPK signaling Annu. Rev. Immunol. 24 2006 771 800
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 771-800
    • Mor, A.1    Philips, M.R.2
  • 13
    • 67650519590 scopus 로고    scopus 로고
    • Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo
    • H. Yan, M.L. Chin, E.A. Horvath, E.A. Kane, and C.M. Pfleger Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo J. Cell Sci. 122 2009 1461 1470
    • (2009) J. Cell Sci. , vol.122 , pp. 1461-1470
    • Yan, H.1    Chin, M.L.2    Horvath, E.A.3    Kane, E.A.4    Pfleger, C.M.5
  • 14
    • 33646070471 scopus 로고    scopus 로고
    • The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain
    • R. Mattera, Y.C. Tsai, A.M. Weissman, and J.S. Bonifacino The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain J. Biol. Chem. 281 2006 6874 6883
    • (2006) J. Biol. Chem. , vol.281 , pp. 6874-6883
    • Mattera, R.1    Tsai, Y.C.2    Weissman, A.M.3    Bonifacino, J.S.4
  • 18
    • 0035171352 scopus 로고    scopus 로고
    • Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex
    • R. Lippé, M. Miaczynska, V. Rybin, A. Runge, and M. Zerial Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex Mol. Biol. Cell 12 2001 2219 2228
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2219-2228
    • Lippé, R.1    Miaczynska, M.2    Rybin, V.3    Runge, A.4    Zerial, M.5
  • 20
    • 34948837802 scopus 로고    scopus 로고
    • Rabaptin-5-independent membrane targeting and Rab5 activation by Rabex-5 in the cell
    • H. Zhu, G. Zhu, J. Liu, Z. Liang, X.C. Zhang, and G. Li Rabaptin-5-independent membrane targeting and Rab5 activation by Rabex-5 in the cell Mol. Biol. Cell 18 2007 4119 4128
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4119-4128
    • Zhu, H.1    Zhu, G.2    Liu, J.3    Liang, Z.4    Zhang, X.C.5    Li, G.6
  • 21
    • 27144529182 scopus 로고    scopus 로고
    • Ubiquitylation and cell signaling
    • K. Haglund, and I. Dikic Ubiquitylation and cell signaling EMBO J. 24 2005 3353 3359
    • (2005) EMBO J. , vol.24 , pp. 3353-3359
    • Haglund, K.1    Dikic, I.2
  • 22
    • 23144449208 scopus 로고    scopus 로고
    • Ubiquitin and ubiquitin-like proteins as multifunctional signals
    • R.L. Welchman, C. Gordon, and R.J. Mayer Ubiquitin and ubiquitin-like proteins as multifunctional signals Nat. Rev. Mol. Cell Biol. 6 2005 599 609
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 599-609
    • Welchman, R.L.1    Gordon, C.2    Mayer, R.J.3
  • 23
    • 34249989118 scopus 로고    scopus 로고
    • Roles of RabGEF1/Rabex-5 domains in regulating FcεRI surface expression and FcεRI-dependent responses in mast cells
    • J. Kalesnikoff, E.J. Rios, C.C. Chen, M. Alejandro Barbieri, M. Tsai, S.Y. Tam, and S.J. Galli Roles of RabGEF1/Rabex-5 domains in regulating FcεRI surface expression and FcεRI-dependent responses in mast cells Blood 109 2007 5308 5317
    • (2007) Blood , vol.109 , pp. 5308-5317
    • Kalesnikoff, J.1    Rios, E.J.2    Chen, C.C.3    Alejandro Barbieri, M.4    Tsai, M.5    Tam, S.Y.6    Galli, S.J.7
  • 24
    • 77955485813 scopus 로고    scopus 로고
    • Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila
    • H. Yan, M. Jahanshahi, E.A. Horvath, H.-Y. Liu, and C.M. Pfleger Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila Curr. Biol. 20 2010 1378 1382
    • (2010) Curr. Biol. , vol.20 , pp. 1378-1382
    • Yan, H.1    Jahanshahi, M.2    Horvath, E.A.3    Liu, H.-Y.4    Pfleger, C.M.5
  • 25
    • 30444436194 scopus 로고    scopus 로고
    • Vps9 domain-containing proteins: Activators of Rab5 GTPases from yeast to neurons
    • D.S. Carney, B.A. Davies, and B.F. Horazdovsky Vps9 domain-containing proteins: Activators of Rab5 GTPases from yeast to neurons Trends Cell Biol. 16 2006 27 35
    • (2006) Trends Cell Biol. , vol.16 , pp. 27-35
    • Carney, D.S.1    Davies, B.A.2    Horazdovsky, B.F.3
  • 26
    • 40749126837 scopus 로고    scopus 로고
    • Integration of transforming growth factor β and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration
    • H. Hu, M. Milstein, J.M. Bliss, M. Thai, G. Malhotra, L.C. Huynh, and J. Colicelli Integration of transforming growth factor β and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration Mol. Cell. Biol. 28 2008 1573 1583
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1573-1583
    • Hu, H.1    Milstein, M.2    Bliss, J.M.3    Thai, M.4    Malhotra, G.5    Huynh, L.C.6    Colicelli, J.7
  • 27
    • 0035408008 scopus 로고    scopus 로고
    • Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1
    • G.G. Tall, M.A. Barbieri, P.D. Stahl, and B.F. Horazdovsky Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1 Dev. Cell 1 2001 73 82
    • (2001) Dev. Cell , vol.1 , pp. 73-82
    • Tall, G.G.1    Barbieri, M.A.2    Stahl, P.D.3    Horazdovsky, B.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.