Anti-HIV and antiplasmodial activity of original flavonoid derivatives

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 16, 2010, Pages 6012-6023

  Casano, Gilles ^a   Dumtre, Aurélien ^b   Pannecouque, Christophe ^c   Hutter, Sébastien ^b   Azas, Nadine ^b   Robin, Maxime ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Chalcone; Flavonoid; HIV 1; HIV 2; Plasmodium falciparum; Selectivity index

Indexed keywords

6 AMINO 2 (2 FLUOROPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 (2 METHOXYPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 (3 FLUOROPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 (3 METHOXYPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 (4 FLUOROPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 (4 METHOXYPHENYL) 4H CHROMEN 4 ONE; 6 AMINO 2 PHENYL 4H CHROMEN 4 ONE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIMALARIAL AGENT; CHALCONE DERIVATIVE; FLAVONOID; N (2 (2 FLUOROPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (2 (2 METHOXYPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (2 (3 FLUOROPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (2 (3 METHOXYPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (2 (4 FLUOROPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (2 (4 METHOXYPHENYL) 4 OXO 4H CHROMEN 6 YL)ACETAMIDE; N (3 (3 (2 FLUOROPHENYL)ACRYLOYL) 4 HYDROXYPHENYL)ACETAMIDE; N (3 (3 (3 FLUOROPHENYL)ACRYLOYL) 4 HYDROXYPHENYL)ACETAMIDE; N (3 (3 (4 FLUOROPHENYL)ACRYLOYL) 4 HYDROXYPHENYL)ACETAMIDE; N (3 CINNAMOYL 4 HYDROXYPHENYL)ACETAMIDE; N (4 HYDROXY 3 (3 (2 METHOXYPHENYL)ACRYLOYL)PHENYL)ACETAMIDE; N (4 HYDROXY 3 (3 (3 (TRIFLUOROMETHYL)PHENYL)ACRYLOYL)PHENYL)ACETAMIDE; N (4 HYDROXY 3 (3 (3 METHOXYPHENYL)ACRYLOYL)PHENYL)ACETAMIDE; N (4 HYDROXY 3 (3 (4 (TRIFLUOROMETHYL)PHENYL)ACRYLOYL)PHENYL)ACETAMIDE; N (4 HYDROXY 3 (3 (4 METHOXYPHENYL)ACRYLOYL)PHENYL)ACETAMIDE; N (4 OXO 2 (3 (TRIFLUOROMETHYL)PHENYL) 4H CHROMEN 6 YL)ACETAMIDE; N (4 OXO 2 (4 (TRIFLUOROMETHYL)PHENYL) 4H CHROMEN 6 YL)ACETAMIDE; N (4 OXO 2 PHENYL 4H CHROMEN 6 YL)ACETAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTI HUMAN IMMUNODEFICIENCY VIRUS ACTIVITY; ANTIMALARIAL ACTIVITY; ANTIPLASMODIAL ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PLASMODIUM FALCIPARUM; PROTON NUCLEAR MAGNETIC RESONANCE; VIROGENESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PLASMODIUM FALCIPARUM;

EID: 77955471651     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.06.067     Document Type: Article

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