Antimicrobial and anticancer efficacy of antineoplastic agent capped gold nanoparticles

Journal of Biomedical Nanotechnology

Volumn 6, Issue 2, 2010, Pages 129-137

  Selvaraj, V ^a   Nirmala Grace, A ^b   Alagar, M ^c   Hamerton, I ^d  

^a ANNA UNIVERSITY   (India)

^b VIT UNIVERSITY   (India)

^c ANNA UNIVERSITY   (India)

^d UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Antimicrobial and anticancer studies; Au@TG complex; Gold nanoparticles; Thioguanine

Indexed keywords

ANTICANCER ACTIVITIES; ANTICANCER DRUG; ANTINEOPLASTIC AGENTS; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; AU NANOPARTICLE; CANCER CELLS; EXPERIMENTAL STUDIES; FOURIER TRANSFORM INFRARED; GOLD NANOPARTICLES; IN-VITRO; MICROCOCCUS LUTEUS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; ULTRAVIOLET-VISIBLE SPECTRA;

CONTROLLED DRUG DELIVERY; CYCLIC VOLTAMMETRY; ENZYME INHIBITION; FOURIER TRANSFORMS; GOLD COMPOUNDS; INFRARED SPECTROSCOPY; MICROORGANISMS; NANOPARTICLES; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; WAVELET TRANSFORMS;

GOLD;

GOLD NANOPARTICLE; TIOGUANINE;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIGER; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DRUG COATING; DRUG EFFICACY; ESCHERICHIA COLI; FLUORESCENCE; FOURIER TRANSFORM MASS SPECTROMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MICROCOCCUS LUTEUS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; ASPERGILLUS; CELL LINE, TUMOR; COLLOIDS; ESCHERICHIA COLI; GOLD; HUMANS; METAL NANOPARTICLES; MICROBIAL SENSITIVITY TESTS; MICROCOCCUS LUTEUS; MICROSCOPY, ELECTRON, TRANSMISSION; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCUS AUREUS; THIOGUANINE;

EID: 77955456908     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2010.1115     Document Type: Article

References (24)

1. T. A. Taton, C. A. Mirkin, and R. L. Letsinger, Scanometric DNA array detection with nanoparticle probes. Science 289, 1757 (2000).
2. R. Elghanian, J. J. Storhoff, R. C. Mucic, R. L. Letsinger, and C. A. Mirkin, Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. Science 277, 1078 (1997).
3. C. C. Lin, Y. C. Yeh, C. Y. Yang, C. L. Chen, G. F. Chen, C. C. Chen, and Y. C. Wu, Selective binding of mannose-encapsulated gold nanoparticles to Type 1 pili in Escherichia coli. J. Am. Chem. Soc. 124, 3508 (2002).
4. W. Welsch, C. Klein, M. VonSchickfus, and S. Hunklinger, Development of a surface acoustic wave immunosensor. Anal. Chem. 68, 2000 (1996).
5. K. L. Prime and G. M. Whitesides, Self-assembled organic monolayers: Model systems for studying adsorption of proteins at surfaces. Science 252, 1164 (1991).
6. A. Kumar and G. M. Whitesides, Features of gold having micrometer to centimeter dimensions can be formed through a combination of stamping with an elastomeric stamp and an alkanethiol "ink" followed by chemical etching. Appl. Phys. Lett. 63, 2002 (1993).
7. Y. G. Sun and Y. N. Xia, Shape-controlled synthesis of gold and silver nanoparticles. Science 298, 2176 (2002).
8. H.-G. Boyen, G. Kastle, F. Weigl, B. Koslowski, C. Dietrich, P. Ziemann, J. P. Spatz, S. Riethmüller, C. Hartmann, M. Moller, G. Schmid, M. G. Garnier, and P. Oelhafen, Oxidation-resistant gold55 clusters. Science 297, 1533 (2002).
9. M. Mammen, S. K. Choi, and G. M. Whitesides, Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew. Chem. Int. Ed. 37, 2754 (1998).
10. M. Mammen, E. I. Shakhnovich, and G. M. Whitesides, Using a convenient, quantitative model for torsional entropy to establish qualitative trends for molecular processes that restrict conformational freedom. J. Org. Chem. 63, 3168 (1998).
11. P. K Stoimenov, R. L. Klinger, G. L. Marchin, and K. J. Klabunde, Metal oxide nanoparticles as bactericidal agents. Langmuir 18, 6679 (2002).
12. H. Gu, PL. Ho, E. Tong, L. Wang, and B. Xu, Presenting vancomycin on nanoparticles to enhance antimicrobial activities. Nano Lett. 3, 1261 (2003).
13. I. Sondi and B. Salopek-Sondi, Silver nanoparticles as antimicrobial agent: A case study on E. coli as a model for Gram-negative bacteria. J. Colloid and Interf. Sci. 275, 177 (2004).
14. V. Selvaraj, M. Alagar, and I. Hamerton, Analytical detection and biological assay of antileukemic drug using gold nanoparticles. Electrochimica Acta 52, 1152 (2006).
15. V. Selvaraj, M. Alagar, and I. Hamerton, Analytical detection and biological assay of antileukemic drug 5-fluorouracil using gold nanoparticles as probe. International Journal of Pharmaceutics 337, 275 (2007).
16. H. Arimoto, K. Nishimura, T. Kinumi, I. Hayakawa, and D. Uemura, Multi-valent polymer of vancomycin: Enhanced antibacterial activity against VRE. Chem. Commun. 1361 (1999).
17. G.-B. Elion and G.-H. Hitchings, The synthesis of 6-thioguanine. J. Am. Chem. Soc. 77, 1676 (1954).
18. R. T. Tom, V. Suryanarayanan, P. Ganapati Reddy, S. Baskaran, and T. Pradeep, Ciprofloxacin-protected gold nanoparticles. Langmuir 20, 1909 (2004).
19. 2+ fluorescence by binding to Au nanoparticles. Langmuir 18, 7077 (2002).
20. H. Li, R. Liang, D. H. Turner, L. J. Rothberg, and S. Duan, Selective quenching of fluorescence from unbound oligonucleotides by gold nanoparticles as a probe of RNA structure. RNA Society 13, 2034 (2007).
21. M. D. Porter, T. B. Bright, D. L. Allara, and C. E. D. Chidsey, Spontaneously organized molecular assemblies. 4. Structural characterization of n-alky1 thiol monolayers on gold by optical ellipsometry, infrared spectroscopy, and electrochemistry. J. Am. Chem. Soc. 109, 3559 (1987).
22. J. Wang, M. Jiang, A. M. Kawde, and R. Polsky, Electrochemically induced deposition of thiol-based monolayers onto closely spaced microelectrodes. Langmuir 16, 9687 (2000).
23. T. Okada, B. K. Patterson, S. Q. Ye, and M. E. Gumey, Aurothiolates inhibit HIV-1 infectivity by Gold(I) ligand exchange with a component of the virion surface. Virology 192, 631 (1993).
24. K. Yamaguchi, H. Ushijima, M. Hisano, Y. Inoue, T. Shimamura, T. Hirano, and E. G. W Müller, Immunomodulatory effect of gold sodium thiomalate on murine acquired immunodeficiency syndrome. Microbiol. Immunol. 45, 549 (2001).