The SH3 domain, but not the catalytic domain, is required for phospholipase C-γ1 to mediate epidermal growth factor-induced mitogenesis

Biochemical and Biophysical Research Communications

Volumn 398, Issue 4, 2010, Pages 719-722

  Xie, Zhongjian ^a,b   Chen, Ying ^c   Pennypacker, Sally D ^a   Zhou, Zhiguang ^b   Peng, Dan ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Catalytic domain; Epidermal growth factor receptor; Mitogenesis; Phospholipase C 1; SH3 domain; Squamous cell carcinoma

Indexed keywords

EPIDERMAL GROWTH FACTOR; PHOSPHOLIPASE C GAMMA1; PROTEIN SH3;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CATALYSIS; GENE DELETION; GENE INACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEDIATOR; MITOGENESIS; MUTANT; PRIORITY JOURNAL; PROTEIN DOMAIN; SQUAMOUS CELL CARCINOMA; X CHROMOSOME;

CARCINOMA, SQUAMOUS CELL; CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL PROLIFERATION; EPIDERMAL GROWTH FACTOR; HUMANS; MITOSIS; PHOSPHOLIPASE C GAMMA; SRC HOMOLOGY DOMAINS;

EID: 77955432031     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.007     Document Type: Article

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