Refinement of the pharmacophore of 3,4-dihydroquinazoline-2(1H)-thiones for their anti-melanogenesis activity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 16, 2010, Pages 4771-4773

  Thanigaimalai, Pillaiyar ^a   Sharma, Vinay K ^a   Lee, Ki Cheul ^a   Yun, Cheong Yong ^b   Kim, Youngsoo ^b   Jung, Sang Hun ^a  

^a Chungnam National University   (South Korea)

^b Chungbuk National University   (South Korea)

Author keywords

3,4 Quinazoline 2(1H) thiones; Inhibitors; Melanogenesis

Indexed keywords

3,4 DIHYDROQUINAZOLINE 2(1H) THIONE DERIVATIVE; ALPHA INTERMEDIN; ANTINEOPLASTIC AGENT; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; MELANIN; THIOKETONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; INHIBITION KINETICS; MELANOGENESIS; MELANOMA B16; NONHUMAN; PHARMACOPHORE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMISTRY; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ALPHA-MSH; ANIMALS; CELL LINE, TUMOR; MELANINS; MICE; STRUCTURE-ACTIVITY RELATIONSHIP; THIONES;

EID: 77955430288     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.06.123     Document Type: Article

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