Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 3, 2010, Pages 1135-1142

  Thanigaimalai, P ^a   Lee, Ki Cheul ^a   Bang, Seong Cheol ^a   Lee, Jee Hyun ^a   Yun, Cheong Yong ^b   Roh, Eunmiri ^b   Hwang, Bang Yeon ^b   Kim, Youngsoo ^b   Jung, Sang Hun ^a  

^a Chungnam National University   (South Korea)

^b Chungbuk National University   (South Korea)

Author keywords

MSH induced melanin production; Hypopimenting; Melanogenesis; Tetrahydropyrimidine 2(1H) thione

Indexed keywords

1 (3 PHENYLPROPYL)IMIDAZOLIDIN 2 ONE; 1 (3 PHENYLPROPYL)IMIDAZOLIDINE 2 THIONE; 1 (4 CHLOROBENZYL)IMIDAZOLIDIN 2 ONE; 1 (4 CHLOROBENZYL)IMIDAZOLIDINE 2 THIONE; 1 (4 CHLOROBENZYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 1 (4 CHLOROBENZYL)TETRAHYDROPYRIMIDINE 2(1H)THIONE; 1 (4 ETHYLBENZYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 1 (4 ETHYLBENZYL)TETRAHYDROPYRIMIDINE 2 (1H)THIONE; 1 (4 METHOXYBENZYL)IMIDAZOLIDIN 2 ONE; 1 (4 METHOXYBENZYL)IMIDAZOLIDINE 2 THIONE; 1 (4 METHYLBENZYL)IMIDAZOLIDIN 2 ONE; 1 (4 METHYLBENZYL)IMIDAZOLIDINE 2 THIONE; 1 (4 TERTBBUTYLBENZYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 1 (4 TERTBUTYLBENZYL)TETRAHYDROPYRIMIDINE 2(1H)THIONE; 1 BENZYLIMIDAZOLIDIN 2 ONE; 1 BENZYLIMIDAZOLIDINE 2 THIONE; 1 BENZYLTETRAHYDROPYRIMIDIN 2 (1H)ONE; 1 BENZYLTETRAHYDROPYRIMIDINE 2(1H) THIONE; 1 PHENYLEHTYLIMIDAZOLIDIN 2 ONE; 1 PHENYLEHTYLIMIDAZOLIDINE 2 THIONE; 2 PYRIMIDINETHIONE DERIVATIVE; 3 (3 PHENYLPROPYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 3 (4 METHOXYBENZYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 3 (4 METHOXYBENZYL)TETRAHYDROPYRIMIDIN 2(1H)THIONE; 3 (4 METHYLBENZYL)TETRAHYDROPYRIMIDIN 2(1H)ONE; 3 PHENYLETHYLTETRAHYDROPYRIMIDIN 2(1H)ONE; ALPHA INTERMEDIN; MONOPHENOL MONOOXYGENASE; TETRAHYDROPYRIMIDINE 2(1H) THIONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BIOASSAY; BIOSYNTHESIS; CATALYSIS; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; MELANOGENESIS;

ALPHA-MSH; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MELANINS; MELANOCYTES; MONOPHENOL MONOOXYGENASE; PYRIMIDINES; THIONES;

EID: 75149181710     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.12.044     Document Type: Article

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