Analogues of N-hydroxy-N′-phenylthiourea and N-hydroxy-N′-phenylurea as inhibitors of tyrosinase and melanin formation

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 12, 2008, Pages 3607-3610

  Criton, Marc ^a   Le Mellay Hamon, Véronique ^a  

^a Laboratoires Mayoly Spindler   (France)

Author keywords

Melanin; N Hydroxy N phenylthiourea and N hydroxy N phenylurea derivatives; Phenylthiourea; Tyrosinase inhibitors

Indexed keywords

ARBUTIN; HYDROQUINONE; HYDROXYUREA; KOJIC ACID; MELANIN; MONOPHENOL MONOOXYGENASE; N HYDROXY N' PHENYLTHIOUREA; N HYDROXY N' PHENYLUREA; PROPYLTHIOURACIL;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HYPERPIGMENTATION; MELANOCYTE; MELANOGENESIS; MOUSE; NONHUMAN;

AGARICALES; ANIMALS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; INHIBITORY CONCENTRATION 50; MELANINS; MELANOCYTES; MELANOMA; MICE; MOLECULAR STRUCTURE; MONOPHENOL MONOOXYGENASE; PEPTIDES; PHENYLTHIOUREA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TOXICITY TESTS;

BASIDIOMYCOTA;

EID: 44649198318     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.04.079     Document Type: Article

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