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Volumn 105, Issue 8, 2010, Pages 1811-1819

Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis

Author keywords

[No Author keywords available]

Indexed keywords

5 ACETAMIDOSALICYLIC ACID; ANTICOAGULANT AGENT; AZATHIOPRINE; C REACTIVE PROTEIN; CORTICOSTEROID; INFLIXIMAB; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 23 RECEPTOR; MERCAPTOPURINE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

EID: 77955426386     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2010.95     Document Type: Article
Times cited : (147)

References (42)
  • 1
    • 33846036986 scopus 로고    scopus 로고
    • IL-23: A master regulator in Crohn disease
    • Neurath MF. IL-23: a master regulator in Crohn disease. Nat Med2007; 13: 26-28
    • (2007) Nat Med , vol.13 , pp. 26-28
    • Neurath, M.F.1
  • 2
    • 67650224449 scopus 로고    scopus 로고
    • Crohn's disease: Th 1, Th 17 or both? the change of a paradigm:new immunological and genetic insights implicate Th 17 cells in the pathogenesisof Crohn's disease
    • Brand S. Crohn's disease: Th 1, Th 17 or both? The change of a paradigm:new immunological and genetic insights implicate Th 17 cells in the pathogenesisof Crohn's disease. Gut 2009; 58: 1152-1167
    • (2009) Gut , vol.58 , pp. 1152-1167
    • Brand, S.1
  • 3
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 ininflammatory bowel disease
    • Fujino S, Andoh A, Bamba S et al. Increased expression of interleukin 17 ininflammatory bowel disease. Gut 2003; 52: 65-70.
    • (2003) Gut , vol.52 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3
  • 4
    • 42449084096 scopus 로고    scopus 로고
    • Role of the novel Th 17 cytokineIL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17Fexpression in active Crohn's disease and analysis of the IL17F p.His161Argpolymorphism in IBD
    • Seiderer J, Elben I, Diegelmann J et al. Role of the novel Th 17 cytokineIL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17Fexpression in active Crohn's disease and analysis of the IL17F p.His161Argpolymorphism in IBD. Inflamm Bowel Dis 2008; 14: 437-445
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 437-445
    • Seiderer, J.1    Elben, I.2    Diegelmann, J.3
  • 5
    • 33645829078 scopus 로고    scopus 로고
    • IL-22 is increased in active Crohn's diseaseand promotes proinflammatory gene expression and intestinal epithelialcell migration
    • Brand S, Beigel F, Olszak T et al. IL-22 is increased in active Crohn's diseaseand promotes proinflammatory gene expression and intestinal epithelialcell migration. Am J Physiol Gastrointest Liver Physiol 2006; 290: G827-38.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Brand, S.1    Beigel, F.2    Olszak, T.3
  • 6
    • 68849124464 scopus 로고    scopus 로고
    • The role of the novel Th 17 cytokineIL-26 in intestinal inflammation
    • Dambacher J, Beigel F, Zitzmann K et al. The role of the novel Th 17 cytokineIL-26 in intestinal inflammation. Gut 2009; 58: 1207-1217
    • (2009) Gut , vol.58 , pp. 1207-1217
    • Dambacher, J.1    Beigel, F.2    Zitzmann, K.3
  • 7
    • 33645005339 scopus 로고    scopus 로고
    • Cell differentiation dependent expressedCCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting inproliferation and migration of colorectal cancer cells
    • Brand S, Olszak T, Beigel F et al. Cell differentiation dependent expressedCCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting inproliferation and migration of colorectal cancer cells. J Cell Biochem2006; 97: 709-723
    • (2006) J Cell Biochem , vol.97 , pp. 709-723
    • Brand, S.1    Olszak, T.2    Beigel, F.3
  • 8
    • 0142053206 scopus 로고    scopus 로고
    • The immunological and genetic basis of inflammatorybowel disease
    • Bouma G, Strober W. The immunological and genetic basis of inflammatorybowel disease. Nat Rev Immunol 2003; 3: 521-533
    • (2003) Nat Rev Immunol , vol.3 , pp. 521-533
    • Bouma, G.1    Strober, W.2
  • 9
    • 0025333699 scopus 로고
    • Tumour necrosis factor-alphaand interferon-gamma production measured at the single cell level innormal and inflamed human intestine
    • MacDonald TT, Hutchings P, Choy MY et al. Tumour necrosis factor-alphaand interferon-gamma production measured at the single cell level innormal and inflamed human intestine. Clin Exp Immunol 1990; 81: 301-305
    • (1990) Clin Exp Immunol , vol.81 , pp. 301-305
    • MacDonald, T.T.1    Hutchings, P.2    Choy, M.Y.3
  • 10
    • 0026531017 scopus 로고
    • Tumour necrosis factor alpha instool as a marker of intestinal inflammation
    • Braegger CP, Nicholls S, Murch SH et al. Tumour necrosis factor alpha instool as a marker of intestinal inflammation. Lancet 1992; 339: 89-91.
    • (1992) Lancet , vol.339 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3
  • 11
    • 0027361432 scopus 로고
    • Construction and initial characterization of amouse-human chimeric anti-TNF antibody
    • Knight DM, Trinh H, Le J et al. Construction and initial characterization of amouse-human chimeric anti-TNF antibody. Mol Immunol 1993; 30: 1443-1453
    • (1993) Mol Immunol , vol.30 , pp. 1443-1453
    • Knight, D.M.1    Trinh Le, H.J.2
  • 12
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab forCrohn's disease: The ACCENT i randomised trial
    • Hanauer SB, Feagan BG, Lichtenstein GR et al. Maintenance infliximab forCrohn's disease: the ACCENT I randomised trial. Lancet 2002; 359: 1541-1549
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 14
    • 0034777502 scopus 로고    scopus 로고
    • Infliximab in the treatment ofsevere steroid-refractory ulcerative colitis: A pilot study
    • Sands BE, Tremaine WJ, Sandborn WJ et al. Infliximab in the treatment ofsevere, steroid-refractory ulcerative colitis: a pilot study. Inflamm Bowel Dis2001; 7: 83-88
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 83-88
    • Sands, B.E.1    Tremaine, W.J.2    Sandborn, W.J.3
  • 15
    • 0038460945 scopus 로고    scopus 로고
    • Infliximab in moderately severeglucocorticoid resistant ulcerative colitis: A randomised controlled trial
    • Probert CS, Hearing SD, Schreiber S et al. Infliximab in moderately severeglucocorticoid resistant ulcerative colitis: a randomised controlled trial. Gut2003; 52: 998-1002.
    • (2003) Gut , vol.52 , pp. 998-1002
    • Probert, C.S.1    Hearing, S.D.2    Schreiber, S.3
  • 16
    • 8444238193 scopus 로고    scopus 로고
    • Infliximab for acute, not steroidrefractoryulcerative colitis: A randomized pilot study
    • Ochsenkuhn T, Sackmann M, Goke B. Infliximab for acute, not steroidrefractoryulcerative colitis: a randomized pilot study. Eur J GastroenterolHepatol 2004; 16: 1167-1171
    • (2004) Eur J GastroenterolHepatol , vol.16 , pp. 1167-1171
    • Ochsenkuhn, T.1    Sackmann, M.2    Goke, B.3
  • 17
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction andmaintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG et al. Infliximab for induction andmaintenance therapy for ulcerative colitis. N Engl J Med 2005; 353: 2462-2476
    • (2005) N Engl J Med , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 18
    • 34247140485 scopus 로고    scopus 로고
    • Predictors of early responseto infliximab in patients with ulcerative colitis
    • Ferrante M, Vermeire S, Katsanos KH et al. Predictors of early responseto infliximab in patients with ulcerative colitis. Inflamm Bowel Dis2007; 13: 123-128
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 123-128
    • Ferrante, M.1    Vermeire, S.2    Katsanos, K.H.3
  • 19
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide associationstudy identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR et al. A genome-wide associationstudy identifies IL23R as an inflammatory bowel disease gene. Science2006; 314: 1461-1463
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 20
    • 39649106413 scopus 로고    scopus 로고
    • Rs1004819 is the main disease-associatedIL23R variant in German Crohn's disease patients: Combined analysis ofIL23R, CARD15, and OCTN1/2 variants
    • Glas J, Seiderer J, Wetzke M et al. rs1004819 is the main disease-associatedIL23R variant in German Crohn's disease patients: combined analysis ofIL23R, CARD15, and OCTN1/2 variants. PLoS ONE 2007; 2: e819.
    • (2007) PLoS ONE , vol.2
    • Glas, J.1    Seiderer, J.2    Wetzke, M.3
  • 21
    • 67650421536 scopus 로고    scopus 로고
    • Novel genetic risk markers for ulcerativecolitis in the chromosome 4q27 region harboring IL2 and IL21 suggest acommon genetic background for ulcerative colitis and celiac disease
    • Glas J, Stallhofer J, Ripke S et al. Novel genetic risk markers for ulcerativecolitis in the chromosome 4q27 region harboring IL2 and IL21 suggest acommon genetic background for ulcerative colitis and celiac disease. Am JGastroenterol 2009; 104: 1737-1744
    • (2009) Am JGastroenterol , vol.104 , pp. 1737-1744
    • Glas, J.1    Stallhofer, J.2    Ripke, S.3
  • 22
    • 56549104968 scopus 로고    scopus 로고
    • IL-23 differentially regulatesthe Th 1/Th 17 balance in ulcerative colitis and Crohn's disease
    • Kobayashi T, Okamoto S, Hisamatsu T et al. IL-23 differentially regulatesthe Th 1/Th 17 balance in ulcerative colitis and Crohn's disease. Gut2008; 57: 1682-1689
    • (2008) Gut , vol.57 , pp. 1682-1689
    • Kobayashi, T.1    Okamoto, S.2    Hisamatsu, T.3
  • 23
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association studyconfirms IL12B and leads to the identification of IL23R as psoriasis-riskgenes
    • Cargill M, Schrodi SJ, Chang M et al. A large-scale genetic association studyconfirms IL12B and leads to the identification of IL23R as psoriasis-riskgenes. Am J Hum Genet 2007; 80: 273-290
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3
  • 24
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14, 500nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR et al. Association scan of 14,500nonsynonymous SNPs in four diseases identifies autoimmunity variants.Nat Genet 2007; 39: 1329-1337
    • (2007) Nat Genet , vol.39 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3
  • 25
    • 38749138182 scopus 로고    scopus 로고
    • Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemicsclerosis
    • Farago B, Magyari L, Safrany E et al. Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemicsclerosis. Ann Rheum Dis 2008; 67: 248-250
    • (2008) Ann Rheum Dis , vol.67 , pp. 248-250
    • Farago, B.1    Magyari, L.2    Safrany, E.3
  • 26
    • 67651209042 scopus 로고    scopus 로고
    • Evidence for associationof an interleukin-23 receptor variant independent of the R381Q variantwith rheumatoid arthritis
    • Hollis-Moffatt JE, Merriman ME, Rodger RA et al. Evidence for associationof an interleukin-23 receptor variant independent of the R381Q variantwith rheumatoid arthritis. Ann Rheum Dis 2009; 68: 1340-1344
    • (2009) Ann Rheum Dis , vol.68 , pp. 1340-1344
    • Hollis-Moffatt, J.E.1    Merriman, M.E.2    Rodger, R.A.3
  • 27
    • 0028292007 scopus 로고
    • Cyclosporine in severe ulcerativecolitis refractory to steroid therapy
    • Lichtiger S, Present DH, Kornbluth A et al. Cyclosporine in severe ulcerativecolitis refractory to steroid therapy. N Engl J Med 1994; 330: 1841-1845
    • (1994) N Engl J Med , vol.330 , pp. 1841-1845
    • Lichtiger, S.1    Present, D.H.2    Kornbluth, A.3
  • 28
    • 33847179443 scopus 로고    scopus 로고
    • A review of activity indicesand efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis
    • D'Haens G, Sandborn WJ, Feagan BG et al. A review of activity indicesand efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 2007; 132: 763-786
    • (2007) Gastroenterology , vol.132 , pp. 763-786
    • D'Haens, G.1    Sandborn, W.J.2    Feagan, B.G.3
  • 29
    • 0033474286 scopus 로고    scopus 로고
    • Building multivariable prognostic and diagnosticmodels: Transformation of the predictors by using fractional polynomials
    • Sauerbrei W, Royston P. Building multivariable prognostic and diagnosticmodels: transformation of the predictors by using fractional polynomials.J Roy Statist Soc (Ser A) 1999; 162: 71-94.
    • (1999) J Roy Statist Soc (Ser A) , vol.162 , pp. 71-94
    • Sauerbrei, W.1    Royston, P.2
  • 30
    • 0036425152 scopus 로고    scopus 로고
    • Corrigendum: Building multivariable prognosticand diagnostic models: Transformation of the predictors by using fractionalpolynomials
    • Sauerbrei W, Royston P. Corrigendum: building multivariable prognosticand diagnostic models: transformation of the predictors by using fractionalpolynomials. J Roy Statist Soc (Ser A) 2002; 162: 399-400.
    • (2002) J Roy Statist Soc (Ser A) , vol.162 , pp. 399-400
    • Sauerbrei, W.1    Royston, P.2
  • 31
    • 33646921786 scopus 로고    scopus 로고
    • Multivariable regressionmodel building by using fractional polynomials: Description of SAS,STATA and R programs
    • Sauerbrei W, Meier-Hirmer C, Benner A et al. Multivariable regressionmodel building by using fractional polynomials: Description of SAS,STATA and R programs. Comput Stat Data Anal 2006; 50: 3464-3485
    • (2006) Comput Stat Data Anal , vol.50 , pp. 3464-3485
    • Sauerbrei, W.1    Meier-Hirmer, C.2    Benner, A.3
  • 33
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practicaland powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practicaland powerful approach to multiple testing. J Roy Statist Soc Ser B(Methodological) 1995; 57: 289-300.
    • (1995) J Roy Statist Soc ser B(Methodological) , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 34
    • 0035050836 scopus 로고    scopus 로고
    • ANCA pattern and LTA haplotype relationshipto clinical responses to anti-TNF antibody treatment in Crohn'sdisease
    • Taylor KD, Plevy SE, Yang H et al. ANCA pattern and LTA haplotype relationshipto clinical responses to anti-TNF antibody treatment in Crohn'sdisease. Gastroenterology 2001; 120: 1347-1355
    • (2001) Gastroenterology , vol.120 , pp. 1347-1355
    • Taylor, K.D.1    Plevy, S.E.2    Yang, H.3
  • 35
    • 0036084752 scopus 로고    scopus 로고
    • Serological markers for prediction ofresponse to anti-tumor necrosis factor treatment in Crohn's disease
    • Esters N, Vermeire S, Joossens S et al. Serological markers for prediction ofresponse to anti-tumor necrosis factor treatment in Crohn's disease. Am JGastroenterol 2002; 97: 1458-1462
    • (2002) Am JGastroenterol , vol.97 , pp. 1458-1462
    • Esters, N.1    Vermeire, S.2    Joossens, S.3
  • 36
    • 0037560163 scopus 로고    scopus 로고
    • An analysis of factors influencing shorttermand sustained response to infliximab treatment for Crohn's disease
    • Arnott ID, McNeill G, Satsangi J. An analysis of factors influencing shorttermand sustained response to infliximab treatment for Crohn's disease.Aliment Pharmacol Ther 2003; 17: 1451-1457
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 1451-1457
    • Arnott, I.D.1    McNeill, G.2    Satsangi, J.3
  • 37
    • 34547204946 scopus 로고    scopus 로고
    • Essential autocrine regulation byIL-21 in the generation of inflammatory T cells
    • Nurieva R, Yang XO, Martinez G et al. Essential autocrine regulation byIL-21 in the generation of inflammatory T cells. Nature 2007; 448: 480-483
    • (2007) Nature , vol.448 , pp. 480-483
    • Nurieva, R.1    Yang, X.O.2    Martinez, G.3
  • 38
    • 39649121919 scopus 로고    scopus 로고
    • Linking genetic susceptibilityto Crohn's disease with Th 17 cell function: IL-22 serum levels are increasedin Crohn's disease and correlate with disease activity and IL23R genotypestatus
    • Schmechel S, Konrad A, Diegelmann J et al. Linking genetic susceptibilityto Crohn's disease with Th 17 cell function: IL-22 serum levels are increasedin Crohn's disease and correlate with disease activity and IL23R genotypestatus. Inflamm Bowel Dis 2008; 14: 204-212
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 204-212
    • Schmechel, S.1    Konrad, A.2    Diegelmann, J.3
  • 39
    • 48949099032 scopus 로고    scopus 로고
    • Long-term outcome aft er infliximabfor refractory ulcerative colitis
    • Ferrante M, Vermeire S, Fidder H et al. Long-term outcome aft er infliximabfor refractory ulcerative colitis. J Crohn's Colitis 2008; 2: 219-225
    • (2008) J Crohn's Colitis , vol.2 , pp. 219-225
    • Ferrante, M.1    Vermeire, S.2    Fidder, H.3
  • 40
    • 49149091258 scopus 로고    scopus 로고
    • Colectomy rate in acute severe ulcerativecolitis in the infliximab era
    • Aratari A, Papi C, Clemente V et al. Colectomy rate in acute severe ulcerativecolitis in the infliximab era. Dig Liver Dis 2008; 40: 821-826
    • (2008) Dig Liver Dis , vol.40 , pp. 821-826
    • Aratari, A.1    Papi, C.2    Clemente, V.3
  • 41
    • 34247149806 scopus 로고    scopus 로고
    • Infliximab for the treatment of ulcerativecolitis: Outcomes in Oxford from 2000 to 2006
    • Jakobovits SL, Jewell DP, Travis SP. Infliximab for the treatment of ulcerativecolitis: outcomes in Oxford from 2000 to 2006. Aliment PharmacolTher 2007; 25: 1055-1060
    • (2007) Aliment PharmacolTher , vol.25 , pp. 1055-1060
    • Jakobovits, S.L.1    Jewell, D.P.2    Travis, S.P.3
  • 42
    • 20444479336 scopus 로고    scopus 로고
    • Infliximab as rescue therapyin severe to moderately severe ulcerative colitis: A randomized, placebocontrolledstudy
    • Jarnerot G, Hertervig E, Friis-Liby I et al. Infliximab as rescue therapyin severe to moderately severe ulcerative colitis: a randomized, placebocontrolledstudy. Gastroenterology 2005; 128: 1805-1811
    • (2005) Gastroenterology , vol.128 , pp. 1805-1811
    • Jarnerot, G.1    Hertervig, E.2    Friis-Liby, I.3


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