Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus

Neuroscience

Volumn 169, Issue 4, 2010, Pages 1567-1574

  Iyo, A H ^a   Feyissa, A M ^a   Chandran, A ^a   Austin, M C ^a   Regunathan, S ^a   Karolewicz, B ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Corticosterone; Frontal cortex; Hippocampus; Metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; Rat

Indexed keywords

CORTICOSTERONE; MESSENGER RNA; METABOTROPIC RECEPTOR 5;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; WESTERN BLOTTING;

EID: 77955424743     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.06.023     Document Type: Article

References (63)

1. Alagarsamy S., Marino M.J., Rouse S.T., Gereau R.W., Heinemann S.F., Conn P.J. Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Nat Neurosci 1999, 2:234-240.
2. Ametamey S.M., Treyer V., Streffer J., Wyss M.T., Schmidt M., Blagoev M., Hintermann S., Auberson Y., Gasparini F., Fischer U.C., Buck A. Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688. J Nucl Med 2007, 48:247-252.
3. Aronica E., Gorter J.A., Ijlst-Keizers H., Rozemuller A.J., Yankaya B., Leenstra S., Troost D. Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. Eur J Neurosci 2003, 17:2106-2118.
4. Autry A.E., Grillo C.A., Piroli G.G., Rothstein J.D., McEwen B.S., Reagan L.P. Glucocorticoid regulation of GLT-1 glutamate transporter isoform expression in the rat hippocampus. Neuroendocrinology 2006, 83:371-379.
5. Brown E.S., Woolston D.J., Frol A., Bobadilla L., Khan D.A., Hanczyc M., Rush A.J., Fleckenstein J., Babcock E., Cullum C.M. Hippocampal volume, spectroscopy, cognition, and mood in patients receiving corticosteroid therapy. Biol Psychiatry 2004, 55:538-545.
6. Brown E.S., Suppes T. Mood symptoms during corticosteroid therapy: a review. Harv Rev Psychiatry 1998, 5:239-246.
7. Chittajallu R., Vignes M., Dev K.K., Barnes J.M., Collingridge G.L., Henley J.M. Regulation of glutamate release by presynaptic kainate receptors in the hippocampus. Nature 1996, 379:78-81.
8. Conn P.J., Pin J.P. Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol 1997, 37:205-237.
9. Deschwanden A., Karolewicz B., Feyissa A.M., Treyer V., Ametamey S.M., Johayem A., Auberson Y., Sovago J., Stockmeier C.A., Buck A., Hasler G. Reduced metabotropic glutamate receptor 5 in major depression. Biol Psychiatry 2010, 67:190S.
10. Dinan T.G. Glucocorticoids and the genesis of depressive illness. A psychobiological model. Br J Psychiatry 1994, 164:365-371.
11. Drevets W.C. Neuroimaging studies of mood disorders. Biol Psychiatry 2000, 48:813-829.
12. Feyissa A.M., Chandran A., Stockmeier C.A., Karolewicz B. Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:70-75.
13. Feyissa A.M., Woolverton W.L., Miguel-Hidalgo J.J., Wang Z., Kyle P.B., Hasler G., Stockmeier C.A., Iyo A.H., Karolewicz B. Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34:279-783.
14. Fontella F.U., Vendite D.A., Tabajara A.S., Porciúncula L.O., da Silva Torres I.L., Jardim F.M., Martini L., Souza D.O., Netto C.A., Dalmaz C. Repeated restraint stress alters hippocampal glutamate uptake and release in the rat. Neurochem Res 2004, 29:1703-1709.
15. Garcia L.S., Comim C.M., Valvassori S.S., Réus G.Z., Stertz L., Kapczinski F., Gavioli E.C., Quevedo J. Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:450-455.
16. Gold P.W., Goodwin F.K., Chrousos G.P. Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (1). N Engl J Med 1988, 319:348-353.
17. Gold P.W., Goodwin F.K., Chrousos G.P. Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (2). N Engl J Med 1988, 319:413-420.
18. Gorzalka B.B., Hanson L.A. Sexual behavior and wet dog shakes in the male rat: regulation by corticosterone. Behav Brain Res 1998, 97:143-151.
19. Gorzalka B., Hanson L., Harrington J., Killam S., Campbell-Meiklejohn D. Conditioned taste aversion: modulation by 5-HT receptor activity and corticosterone. Eur J Pharmacol 2003, 471:129-134.
20. Gourley S.L., Kedves A.T., Olausson P., Taylor J.R. A history of corticosterone exposure regulates fear extinction and cortical NR2B, GluR2/3, and BDNF. Neuropsychopharmacology 2009, 34:707-716.
21. Gregus A., Wintink A.J., Davis A.C., Kalynchuk L.E. Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats. Behav Brain Res 2005, 156:105-114.
22. Gry M., Rimini R., Strömberg S., Asplund A., Pontén F., Uhlén M., Nilsson P. Correlations between RNA and protein expression profiles in 23 human cell lines. BMC Genomics 2009, 10:365.
23. Hanson L.A., Gorzalka B.B. The influence of corticosterone on serotonergic stereotypy and sexual behavior in the female rat. Behav Brain Res 1999, 104:27-35.
24. Hashimoto K. Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res Rev 2009, 61:105-123.
25. Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000, 23:488-501.
26. Hunter R.G., Bellani R., Bloss E., Costa A., McCarthy K., McEwen B.S. Regulation of kainate receptor subunit mRNA by stress and corticosteroids in the rat hippocampus. PLoS One 2009, 4:e4328.
27. Iyo A.H., Kieran N., Chandran A., Albert P.R., Wicks I., Bissette G., Austin M.C. Differential regulation of the serotonin 1A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress. Neuroscience 2009, 163:1119-1127.
28. Joëls M., Karst H., DeRijk R., de Kloet E.R. The coming out of the brain mineralocorticoid receptor. Trends Neurosci 2008, 31:1-7.
29. Joëls M., Krugers H.J., Lucassen P.J., Karst H. Corticosteroid effects on cellular physiology of limbic cells. Brain Res 2009, 1293:91-100.
30. Johnson K.A., Conn P.J., Niswender C.M. Glutamate receptors as therapeutic targets for Parkinson's disease. CNS Neurol Disord Drug Targets 2009, 8:475-491.
31. Johnson S.A., Fournier N.M., Kalynchuk L.E. Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor. Behav Brain Res 2006, 168:280-288.
32. Kalynchuk L.E., Gregus A., Boudreau D., Perrot-Sinal T.S. Corticosterone increases depression-like behavior, with some effects on predator odorinduced defensive behavior, in male and female rats. Behav Neurosci 2004, 118:1365-1377.
33. Karst H., Berger S., Turiault M., Tronche F., Schütz G., Joëls M. Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone. Proc Natl Acad Sci U S A 2005, 102:19204-19207.
34. Kelly W.F., Checkley S.A., Bender D.A., Mashiter K. Cushing's syndrome and depression-a prospective study of 26 patients. Br J Psychiatry 1983, 142:16-19.
35. Kieran N., Ou X.M., Iyo A.H. Chronic social defeat downregulates the 5-HT1A receptor but not Freud-1 or NUDR in the rat prefrontal cortex. Neurosci Lett 2010, 469:380-384.
36. Kuwajima M., Hall R.A., Aiba A., Smith Y. Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. J Comp Neurol 2004, 474:589-602.
37. Magariños A.M., McEwen B.S. Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience 1995, 69:89-98.
38. Mao L., Yang L., Tang Q., Samdani S., Zhang G., Wang J.Q. The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons. J Neurosci 2005, 25:2741-2752.
39. Marks W., Fournier N.M., Kalynchuk L.E. Repeated exposure to corticosterone increases depression-like behavior in two different versions of the forced swim test without altering nonspecific locomotor activity or muscle strength. Physiol Behav 2009, 98:67-72.
40. Ouattara B., Gasparini F., Morissette M., Grégoire L., Samadi P., Gomez-Mancilla B., Di Paolo T. Effect of L-Dopa on metabotropic glutamate receptor 5 in the brain of parkinsonian monkeys. J Neurochem 2010, 113:715-724.
41. Palucha A., Pilc A. Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. Pharmacol Ther 2007, 115:116-147.
42. Paquet M., Asay M.J., Fam S.R., Inuzuka H., Castleberry A.M., Oller H., Smith Y., Yun C.C., Traynelis S.F., Hall R.A. The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity. J Biol Chem 2006, 281:29949-29961.
43. Paquet M., Smith Y. Group I metabotropic glutamate receptors in the monkey striatum: subsynaptic association with glutamatergic and dopaminergic afferents. J Neurosci 2003, 23:7659-7669.
44. Pariante C.M., Miller A.H. Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry 2001, 49:391-404.
45. Patten S.B., Williams J.V., Love E.J. Self-reported depressive symptoms following treatment with corticosteroids and sedative-hypnotics. Int J Psychiatry Med 1996, 26:15-24.
46. Piccinin S., Cinque C., Calò L., Molinaro G., Battaglia G., Maggi L., Nicoletti F., Melchiorri D., Eusebi F., Massey P.V., Bashir Z.I. Interaction between Ephrins and mGlu5 metabotropic glutamate receptors in the induction of long-term synaptic depression in the hippocampus. J Neurosci 2010, 30:2835-2843.
47. Pilc A., Chaki S., Nowak G., Witkin J.M. Mood disorders: regulation by metabotropic glutamate receptors. Biochem Pharmacol 2008, 75:997-1006.
48. Reagan L.P., Rosell D.R., Wood G.E., Spedding M., Munoz C., Rothstein J., McEwen B.S. Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine. Proc Natl Acad Sci U S A 2004, 101:2179-2184.
49. Reul J.M., de Kloet E.R. Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 1985, 117:2505-2511.
50. Reus V.I., Miner C. Evidence for physiological effects of hypercortisolemia in psychiatric patients. Psychiatry Res 1985, 14:47-56.
51. Sachar E.J., Hellman L., Roffwarg H.P., Halpern F.S., Fukushima D.K., Gallagher T.F. Disrupted 24-h patterns of cortisol secretion in psychotic depression. Arch Gen Psychiatry 1973, 28:19-24.
52. Sanacora G. Do glutamatergic agents represent a new class of antidepressant drugs?. Part 1. J Clin Psychiatry 2009, 70:1473-1475.
53. Sanacora G., Zarate C.A., Krystal J.H., Manji H.K. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov 2008, 7:426-437.
54. Sterner E.Y., Kalynchuk L.E. Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: relevance to depression. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34:777-790.
55. Toth E., Gersner R., Wilf-Yarkoni A., Raizel H., Dar D.E., Richter-Levin G., Levit O., Zangen A. Age-dependent effects of chronic stress on brain plasticity and depressive behavior. J Neurochem 2008, 107:522-532.
56. Valentine G.W., Sanacora G. Targeting glial physiology and glutamate cycling in the treatment of depression. Biochem Pharmacol 2009, 78:431-439.
57. Venero C., Borrell J. Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats. Eur J Neurosci 1999, 11:2465-2473.
58. Wang C.C., Wang S.J. Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals. Synapse 2009, 63:745-751.
59. Watanabe Y., Gould E., Cameron H.A., Daniels D.C., McEwen B.S. Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons. Hippocampus 1992, 2:431-435.
60. Wellman C.L. Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J Neurobiol 2001, 49:245-253.
61. Wierońska J.M., Brański P., Szewczyk B., Pałucha A., Papp M., Gruca P., Moryl E., Pilc A. Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. Pol J Pharmacol 2001, 53:659-662.
62. Witkin J.M., Marek G.J., Johnson B.G., Schoepp D.D. Metabotropic glutamate receptors in the control of mood disorders. CNS Neurol Disord Drug Targets 2007, 6:87-100.
63. Woolley C.S., Gould E., McEwen B.S. Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res 1990, 531:225-231.