Corticosterone increases depression-like behavior, with some effects on predator odor-induced defensive behavior, in male and female rats

Behavioral Neuroscience

Volumn 118, Issue 6, 2004, Pages 1365-1377

  Kalynchuk, Lisa E ^a   Gregus, Andrea ^a   Boudreau, Daniel ^a   Perrot Sinal, Tara S ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; CORTICOSTERONE 21 ACETATE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; DEPRESSION; FEMALE; FORCED SWIMMING TEST; HORMONE ACTION; MALE; NONHUMAN; ODOR; OPEN FIELD BEHAVIOR; PREDATOR; RAT; STRESS;

AGGRESSION; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; CORTICOSTERONE; DEPRESSION; EXPLORATORY BEHAVIOR; FEMALE; MALE; ODORS; RATS; RATS, LONG-EVANS; SEX CHARACTERISTICS; SWIMMING; TIME FACTORS;

EID: 5644271792     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.118.6.1365     Document Type: Article

References (74)

1. Alonso, S. J., Castellano, M. A., Afonso, D., & Rodriguez, M. (1991). Sex differences in behavioral despair: Relationships between behavioral despair and open field activity. Physiology & Behavior, 49, 69-72.
2. Anderson, S. M., Asviolakis, G. A., Bauman, R. A., Chu, K. Y., Ghosh, S., & Kant, J. (1996). Effects of chronic stress on food acquisition, plasma hormones and the estrous cycle of female rats. Physiology & Behavior, 60, 325-329.
3. Archer, J. (1975). Rodent sex differences in emotional and related behavior. Behavioral Biology, 14, 451-479.
4. Armario, A., Gavalda, A., & Marti, O. (1988). Forced swimming test in rats: Effect of desipramine administration and the period of exposure to the test on struggling behavior, swimming, immobility, and defecation in rats. European Journal of Pharmacology, 158, 207-212.
5. Axelson, J. F. (1987). Forced swimming alters vaginal estrous cycles, body composition, and steroid levels without disrupting lordosis behavior or fertility in rats. Physiology & Behavior, 41, 471-479.
6. Barr, A. M., Brotto, L. A., & Phillips, A. G. (2000). Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats. Brain Research, 875, 196-201.
7. Beatty, W. W. (1979). Gonadal hormones and sex differences in nonreproductive behaviors in rodents: Organizational and activational influences. Hormones and Behavior, 12, 112-163.
8. Beatty, W. W., & Beatty, P. A. (1970). Hormonal determinants of sex differences in avoidance behavior and reactivity to electric shock in the rat. Journal of Comparative Physiological Psychology, 73, 446-455.
9. Blanchard, D. C., Blanchard, R. J., De Padua Carobrez, A., Veniegas, R., Rodgers, R. J., & Shepherd, J. K. (1992). MK-801 produces a reduction in anxiety-related antipredator defensiveness in male and female rats and a gender-dependent increase in locomotor behavior. Psychopharmacology, 108, 352-362.
10. Blanchard, D. C., Griebel, G., & Blanchard, R. J. (1995). Gender bias in the preclinical psychopharmacology of anxiety: Male models for (predominantly) female disorders. Journal of Psychopharmacology, 9, 79-82.
11. Blanchard, D. C., Griebel, G., & Blanchard, R. J. (2003). Conditioning and residual emotionality effects of predator stimuli: Some reflections on stress and emotion. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 27, 1177-1185.
12. Blanchard, R. J., & Blanchard, D. C. (1989). Antipredator defensive behaviors in a visible burrow system. Journal of Comparative Psychology, 103, 70-82.
13. Blanchard, R. J., Blanchard, D. C., Rodgers, J., & Weiss, S. M. (1990). The characterization and modelling of antipredator defensive behavior. Neuroscience & Biobehavioral Reviews, 14, 463-472.
14. Bowman, R. E., Ferguson, D., & Luine, V. N. (2002). Effects of chronic restraint stress and estradiol on open field activity, spatial memory, and monoaminergic neurotransmitters in ovariectomized rats. Neuroscience, 113, 401-410.
15. Bowman, R. E., Zrull, M. C., & Luine, V. N. (2001). Chronic restraint stress enhances radial arm maze performance in female rats. Brain Research, 904, 279-289.
16. Broadhurst, P. L. (1969). Psychogenetics of emotionality in the rat. Annals of the New York Academy of Sciences: Vol. 159. Experimental approaches to the study of emotional behavior (pp. 806-824). New York: New York Academy of Sciences.
17. Brotto, L. A., Barr, A. M., & Gorzalka, B. B. (2000). Sex differences in forced-swim and open-field test behaviors after chronic administration of melatonin. European Journal of Pharmacology, 402, 87-93.
18. Brotto, L. A., Gorzalka, B. B., & Barr, A. M. (2001). Paradoxical effects of chronic corticosterone on forced swim behaviors in aged male and female rats. European Journal of Pharmacology, 424, 203-209.
19. Conrad, C. D., Magarinos, A. M., LeDoux, J. E., & McEwen, B. S. (1999). Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behavioral Neuroscience, 113, 902-913.
20. de Kloet, R. E., Vreugdenhil, E., Oitzl, M. S., & Joels, M. (1998). Brain corticosteroid receptor balance in health and disease. Endocrinology Reviews, 19, 269-301.
21. Dielenberg, R. A., Carrive, P., & McGregor, I. S. (2001). The cardiovascular and behavioral response to cat odor in rats: Unconditioned and conditioned effects. Brain Research, 897, 228-237.
22. Dielenberg, R. A., & McGregor, I. S. (2001). Defensive behavior in rats towards predatory odors: A review. Neuroscience & Biobehavioral Reviews, 25, 597-609.
23. Dinan, T. G. (2001). Novel approaches to the treatment of depression by modulating the hypothalamic-pituitary-adrenal axis. Human Psychopharmacology, 16, 89-93.
24. Duman, R. S., Malberg, J., Nakagawa, S., & D'Sa, C. (2000). Neuronal plasticity and survival in mood disorders. Biological Psychiatry, 48, 732-739.
25. Falconer, E. M., & Galea, L. A. M. (2003). Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult rats. Brain Research, 975, 22-36.
26. Frye, C. A., & Walf, A. A. (2002). Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats. Hormones and Behavior, 41, 306-315.
27. Fuchs, E., & Gould, E. (2000). Mini-review: In vivo neurogenesis in the adult brain: Regulation and functional implications. European Journal of Neuroscience, 12, 2211-2214.
28. Galea, L. A. M., McEwen, B. S., Tanapat, P., Deak, T., Spencer, R. L., & Dhabnar, F. S. (1997). Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress. Neuroscience, 81, 689-697.
29. Galea, L. A. M., Wide, J. K., & Barr, A. M. (2001). Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression. Behavioural Brain Research, 122, 1-9.
30. Garcia-Segura, L. M., Azcoitia, I., & DonCarlos, L. L. (2001). Neuroprotection by estradiol. Progress in Neurobiology, 63, 29-60.
31. Gonzalez, A. S., Rodriguez-Echandia, E. L., Cabrera, R., & Foscolo, M. R. (1994). Neonatal chronic stress induces subsensitivity to chronic stress in adult rats: II. Effects on estrous cycle in females. Physiology & Behavior, 5, 591-595.
32. Gorzalka, B. B., & Hanson, L. A. (1998). Sexual behavior and wet dog shakes in the male rat: Regulation by corticosterone. Behavioural Brain Research, 97, 143-151.
33. Gregus, A., Wintink, A. J., Davis, A. C., & Kalynchuk, L. E. (in press). Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats. Behavioural Brain Research.
34. Hamilton, J. A., & Halbreich, U. (1993). Special aspects of neuropsychiatric illness in women. Annual Review of Medicine, 44, 356-364.
35. Herman, J. P., & Cullinan, W. E. (1997). Neurocircuitry of stress: Central control of the hypothalamo-pituitary-adrenocortical axis. Trends in Neurosciences, 20, 78-84.
36. Hill, M. N., Brotto, L. A., Lee, T. T. Y., & Gorzalka, B. B. (2003). Corticosterone attenuates the antidepressant-like effects elicited by melatonin in the forced swim test in both male and female rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 27, 905-911.
37. Johnson, S. A., Stamp, J. A., & Kalynchuk, L. E. (2004, October). Repeated corticosterone injections faciliate depression-like behavior and suppress hypothalamic-pituitary-adrenal axis activation in a dose-dependent manner. Poster session presented at the annual meeting of the Society for Neuroscience, San Diego, CA (Program No. 762.7) Retrieved from http://sfn.scholarone.com/itin2004/index.html
38. Kalynchuk, L. E., Pinel, J. P. J., Treit, D., & Kippin, T. E. (1997). Changes in emotional behavior produced by long-term amygdala kindling in rats. Biological Psychiatry, 41, 438-451.
39. Karten, Y. J. G., Nair, S. M., van Essen, L., Sibug, R., & Joels, M. (1999). Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons. Proceedings of the National Academy of Sciences, USA, 96, 13456-13461.
40. Kavaliers, M., & Choleris, E. (2001). Antipredator responses and defensive behavior: Ecological and ethological approaches for the neurosciences. Neuroscience & Biobehavioral Reviews, 25, 577-586.
41. Kessler, R. C., McGonagle, K. A., Swartz, M., Blazer, D. G., & Nelson, C. B. (1993). Sex and depression in the national comorbidity survey I: Lifetime prevalence, chronicity and recurrence. Journal of Affective Disorders, 29, 85-96.
42. Lucki, I. (1997). The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behavioral Pharmacology, 8, 523-532.
43. Luine, V., Villegas, M., Martinez, C., & McEwen, B. S. (1994). Repeated stress causes reversible impairments of spatial memory performance. Brain Research, 639, 167-170.
44. MacQueen, G. M., Campbell, S., McEwen, B. S., Macdonald, K., Amano, S., Joffe, R. T., et al. (2003). Course of illness, hippocampal function, and hippocampal volume in major depression. Proceedings of the National Academy of Sciences, USA, 100, 1387-1392.
45. Magarinos, A. M., & McEwen, B. S. (1995). Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Comparison of stressors. Neuroscience, 69, 83-88.
46. McEwen, B. S. (2000). The neurobiology of stress: From serendipity to clinical relevance. Brain Research, 886, 172-189.
47. Mineka, S., Watson, D., & Clark, A. L. (1998). Comorbidity of anxiety and unipolar mood disorders. Annual Review of Psychology, 49, 377-412.
48. Nestler, E. J., Barrot, M., DiLeone, R. J., Eisch, A. J., Gold, S. J., & Monteggia, L. M. (2002). Neurobiology of depression. Neuron, 34, 13-25.
49. Nestler, E. J., Gould, E., Manji, H., Bucan, M., Duman, R. S., Gershenfeld, H. K., et al. (2002). Preclinical models: Status of basic research in depression. Biological Psychiatry, 52, 503-528.
50. Palanza, P. (2001). Animal models of anxiety and depression: How are females different? Neuroscience & Biobehavioral Reviews, 25, 219-233.
51. Papaioannou, A., Gerozissis, K., Prokopiou, A., Solaris, S., & Stylianopoulou, F. (2002). Sex differences in the effects of neonatal handling on the animal's response to stress and the vulnerability for depressive behaviour. Behavioural Brain Research, 129, 131-139.
52. Parker, K. J., Schatzberg, A. F., & Lyons, D. M. (2003). Neuroendocrine aspects of hypercortisolism in major depression. Hormones and Behavior, 43, 60-66.
53. Perrot-Sinal, T. S., Ossenkopp, K. P., & Kavaliers, M. (1999). Brief predator odor exposure activates the HPA axis independent of locomotor changes. NeuroReport, 10, 775-780.
54. Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003). Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM NCAM expression in the adult rat dentate gyrus. European Journal of Neuroscience, 17, 879-886.
55. Porsolt, R. D., Anton, G., Blavet, N., & Jalfre, M. (1978). Behavioural despair in rats: A new model sensitive to antidepressant treatments. European Journal of Pharmacology, 47, 379-391.
56. Porsolt, R. D., Le Pichon, M., & Jalfre, M. (1977, April 21). Depression: A new animal model sensitive to antidepressant treatments. Nature, 266, 730-732.
57. Ramos, A., & Mormède, P. (1998). Stress and emotionality: A multidimensional and genetic approach. Neuroscience & Biobehavioral Reviews, 22, 33-57.
58. Rodriguez-Echandia, E. L., Gonzalez, A. S., Cabrera, R., & Fracchia, L. N. (1988). A further analysis of behavioral and endocrine effects of unpredictable chronic stress. Physiology & Behavior, 43, 789-795.
59. Sapolsky, R. M. (2000). Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Archives of General Psychiatry, 57, 925-935.
60. Sonino, N., & Fava, G. (2002). Residual symptoms in depression: An emerging therapeutic concept. Progress in Neuropsychopharmacology & Biological Psychiatry, 26, 763-770.
61. Sousa, N., Almeida, O. F. X., Holsboer, F., Paula-Barbosa, M. M., & Madeira, M. D. (1998). Maintenance of hippocampal cell numbers in young and aged rats submitted to chronic unpredictable stress. Comparison with the effects of corticosterone treatment. Stress, 2, 237-249.
62. Sousa, N., Lukoyanov, N. V., Madeira, M. D., Almeida, O. F. X., & Paula-Barbosa, M. M. (2000). Reorganization of the morphology of hippocampal neuritis and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience, 97, 253-266.
63. Sousa, N., Madeira, M. D., Paula-Barbosa, M. M. (1998). Effects of corticosterone treatment and rehabilitation on the hippocampal formation of neonatal and adult rats. An unbiased stereological study. Brain Research, 2, 199-210.
64. Sousa, N., Paula-Barbosa, M. M., & Almeida, O. F. X. (1999). Ligand and subfield specificity of corticoid-induced neuronal loss in the rat hippocampal formation. Neuroscience, 89, 1079-1087.
65. Steenbergen, H. L., Farabollini, F., Heinsbroek, R. P. W., & Van de Poll, N. E. (1991). Sex-dependent effects of aversive stimulation on holeboard and elevated plus-maze behavior. Behavioural Brain Research, 43, 159-165.
66. Steenbergen, H. L., Heinsbroek, R. P. W., Van Hest, A., & Van de Poll, N. E. (1990). Sex-dependent effects of inescapable shock administration on shuttlebox-escape performance and elevated plus-maze behavior. Physiology & Behavior, 48, 571-576.
67. Stock, H. S., Ford, K., & Wilson, M. A. (2000). Gender and gonadal hormone effects in the olfactory bulbectomy animal model of depression. Pharmacology Biochemistry and Behavior, 67, 183-191.
68. Tsigos, C., & Chrousos, G. P. (2002). Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. Journal of Psychosomatic Research, 53, 865-871.
69. Vyas, A., Mitra, R., Rao, B. S., & Chattarji, S. (2002). Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons. Journal of Neuroscience, 22, 6810-6818.
70. Wallace, K. J., & Rosen, J. B. (2000). Predator odor as an unconditioned fear stimulus in rats: Elicitation of freezing by trimethylthiazoline, a component of fox feces. Behavioral Neuroscience, 114, 912-922.
71. Wintink, A. J., Young, N. A., Davis, A. C., Gregus, A., & Kalynchuk, L. E. (2003). Kindling-induced emotional behavior in male and female rats. Behavioral Neuroscience, 117, 632-640.
72. Woolley, C. S., Gould, E., & McEwen, B. S. (1990). Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Research, 531, 225-231.
73. Young, E. A. (1998). Sex differences and the HPA axis: Implications for psychiatric disease. Journal of Gender-Specific Medicine, 1, 21-27.
74. Young, E. A., & Korszun, A. (2002). The hypothalamic-pituitary- gonadal axis in mood disorders. Endocrinology and Metabolism Clinics of North America, 31, 63-78.