A double Mannich approach to the synthesis of substituted piperidones - Application to the synthesis of substituted E-ring analogues of methyllycaconitine

Tetrahedron

Volumn 66, Issue 35, 2010, Pages 7179-7191

  Chan, Yinman ^a   Balle, Jared ^a   Kevin Sparrow, J ^a   Boyd, Peter D W ^a   Brimble, Margaret A ^a   Barker, David ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

4 Piperidones; Mannich reaction; Methyllycacontine; Multicomponent reaction

Indexed keywords

(1 BUTYL 3,5 DIMETHYL 4 METHOXYPIPERIDIN 3 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; (1 BUTYL 5 ETHYL 4 METHOXY 3 METHYLPIPERIDIN 3 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; (1 BUTYL 5 ISOPROPYL 4 METHOXY 3 METHYLPIPERIDIN 3 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; 1 BUTYL 4 METHOXY 3 METHYL 5 PHENYLPIPERIDIN 3 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; 5 ALLYL 1 BUTYL 4 METHOXY 3 METHYLPIPERIDIN 3 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; 7 BUTYL 9 METHYL 2,5,5A,6,7,8,9,9A OCTAHYDROOXEPINO[3,2 C]PYRIDIN 9 YL)METHYL 2 (3 METHYL 2,5 DIOXO 2,5 DIHYDRO 1H PYRROL 1 YL)BENZOIC ACID; ETHYL 1 (3 PHENYLPROPYL) 3,5,5 TRIMETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BENZYL 3 ETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BENZYL 3 METHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 3 METHYL 4 OXO 5 PHENYLPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 3 METHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 3,5 DIMETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 3,5,5 TRIMETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 5 ETHYL 3 METHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 BUTYL 5 ISOPROPYL 3 METHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 1 TERT BUTYL 3,5 DIETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 5 ALLYL 1 BUTYL 3 METHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 5 ALLYL 1,5 DIMETHYL 4 OXOPIPERIDINE 3 CARBOXYLIC ACID; ETHYL 5 METHYL 4 OXO 1 (3 PHENYLPROPYL) PIPERIDINE 3 CARBOXYLIC ACID; METHYLLYCACONITINE; PIPERIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; MANNICH REACTION; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS;

DELPHINIUM;

EID: 77955414720     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.06.084     Document Type: Article

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