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Volumn 62, Issue 8, 2010, Pages 2401-2411

Reversing interleukin-2 inhibition mediated by anti-double-stranded DNA autoantibody ameliorates glomerulonephritis in MRL-lpr/lpr mice

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ARGININE DERIVATIVE; DECA ARGININE; DOUBLE STRANDED DNA ANTIBODY; GLYCOGEN SYNTHASE KINASE 3; INTERLEUKIN 2; LITHIUM CHLORIDE; MONOCLONAL ANTIBODY 9D7; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 77955402786     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27487     Document Type: Article
Times cited : (6)

References (42)
  • 1
    • 0030850910 scopus 로고    scopus 로고
    • Lupus nephritis
    • Berden JH. Lupus nephritis. Kidney Int 1997;52:538-58.
    • (1997) Kidney Int , vol.52 , pp. 538-558
    • Berden, J.H.1
  • 3
    • 0014259755 scopus 로고
    • Pathogenesis of the glomerulonephritis of NZB/W mice
    • Lambert PH, Dixon FJ. Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med 1968;127:507-22.
    • (1968) J Exp Med , vol.127 , pp. 507-522
    • Lambert, P.H.1    Dixon, F.J.2
  • 4
    • 0023271978 scopus 로고
    • The NZB x SWR model of lupus nephritis. II. Autoantibodies deposited in renal lesions show a distinctive and restricted idiotypic diversity
    • Gavalchin J, Datta SK. The NZB x SWR model of lupus nephritis. II. Autoantibodies deposited in renal lesions show a distinctive and restricted idiotypic diversity. J Immunol 1987;138:138-48. (Pubitemid 17218411)
    • (1987) Journal of Immunology , vol.138 , Issue.1 , pp. 138-148
    • Gavalchin, J.1    Datta, S.K.2
  • 5
    • 0025224956 scopus 로고
    • A small proportion of cationic antibodies in immune complexes is sufficient to mediate their deposition in glomeruli
    • Gauthier VJ, Mannik M. A small proportion of cationic antibodies in immune complexes is sufficient to mediate their deposition in glomeruli. J Immunol 1990;145:3348-52.
    • (1990) J Immunol , vol.145 , pp. 3348-3352
    • Gauthier, V.J.1    Mannik, M.2
  • 6
    • 0025159214 scopus 로고
    • Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus
    • Tsao BP, Ebling FM, Roman C, Panosian-Sahakian N, Calame K, Hahn BH. Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus. J Clin Invest 1990;85:530-40. (Pubitemid 20070062)
    • (1990) Journal of Clinical Investigation , vol.85 , Issue.2 , pp. 530-540
    • Tsao, B.P.1    Ebling, F.M.2    Roman, C.3    Panosian-Sahakian, N.4    Calame, K.5    Hahn, B.H.6
  • 7
    • 0026753816 scopus 로고
    • Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites
    • Vlahakos DV, Foster MH, Adams S, Katz M, Ucci AA, Barrett KJ, et al. Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites. Kidney Int 1992;41:1690-700.
    • (1992) Kidney Int , vol.41 , pp. 1690-1700
    • Vlahakos, D.V.1    Foster, M.H.2    Adams, S.3    Katz, M.4    Ucci, A.A.5    Barrett, K.J.6
  • 8
    • 50949083014 scopus 로고    scopus 로고
    • Predictive value of anti-dsDNA autoantibodies: Importance of the assay
    • Munoz LE, Gaipl US, Herrmann M. Predictive value of anti-dsDNA autoantibodies: importance of the assay. Autoimmun Rev 2008;7:594-7.
    • (2008) Autoimmun Rev , vol.7 , pp. 594-597
    • Munoz, L.E.1    Gaipl, U.S.2    Herrmann, M.3
  • 9
    • 39549111438 scopus 로고    scopus 로고
    • Anti-DNA antibodies in the pathogenesis of lupus nephritis - The emerging mechanisms
    • Yung S, Chan TM. Anti-DNA antibodies in the pathogenesis of lupus nephritis - the emerging mechanisms. Autoimmun Rev 2008;7:317-21.
    • (2008) Autoimmun Rev , vol.7 , pp. 317-321
    • Yung, S.1    Chan, T.M.2
  • 10
    • 0043180525 scopus 로고    scopus 로고
    • Antibody penetration into living cells: Pathogenic, preventive and immuno-therapeutic implications
    • DOI 10.2174/1381612033454379
    • Ruiz-Arguelles A, Rivadeneyra-Espinoza L, and Alarcon-Segovia D. Antibody penetration into living cells: pathogenic, preventive and immuno-therapeutic implications. Curr Pharm Des 2003;9:1881-7. (Pubitemid 37010091)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.23 , pp. 1881-1887
    • Ruiz-Arguelles, A.1    Rivadeneyra-Espinoza, L.2    Alarcon-Segovia, D.3
  • 11
    • 1642321982 scopus 로고    scopus 로고
    • IL-2, regulatory T cells, and tolerance
    • Nelson BH. IL-2, regulatory T cells, and tolerance. J Immunol 2004;172:3983-8.
    • (2004) J Immunol , vol.172 , pp. 3983-3988
    • Nelson, B.H.1
  • 12
    • 0024548313 scopus 로고
    • Contingent genetic regulatory events in T lymphocyte activation
    • Crabtree GR. Contingent genetic regulatory events in T lymphocyte activation. Science 1989;243:355-61.
    • (1989) Science , vol.243 , pp. 355-361
    • Crabtree, G.R.1
  • 13
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • DOI 10.1146/annurev.immunol.15.1.707
    • Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 1997;15:707-47. (Pubitemid 27169297)
    • (1997) Annual Review of Immunology , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 14
    • 0032759619 scopus 로고    scopus 로고
    • The - 180 site of the IL-2 promoter is the target of CREB/CREM binding in T cell anergy
    • Powell JD, Lerner CG, Ewoldt GR, Schwartz RH. The - 180 site of the IL-2 promoter is the target of CREB/CREM binding in T cell anergy. J Immunol 1999;163:6631-9.
    • (1999) J Immunol , vol.163 , pp. 6631-6639
    • Powell, J.D.1    Lerner, C.G.2    Ewoldt, G.R.3    Schwartz, R.H.4
  • 15
    • 0038281190 scopus 로고    scopus 로고
    • Suppression of T cell signaling by polyunsaturated fatty acids: Selectivity in inhibition of mitogen-activated protein kinase and nuclear factor activation
    • Zeyda M, Szekeres AB, Saemann MD, Geyeregger R, Stockinger H, Zlabinger GJ, et al. Suppression of T cell signaling by polyun-saturated fatty acids: selectivity in inhibition of mitogen-activated protein kinase and nuclear factor activation. J Immunol 2003;170:6033-9. (Pubitemid 36682584)
    • (2003) Journal of Immunology , vol.170 , Issue.12 , pp. 6033-6039
    • Zeyda, M.1    Szekeres, A.B.2    Saemann, M.D.3    Geyeregger, R.4    Stockinger, H.5    Zlabinger, G.J.6    Waldhausl, W.7    Stulnig, T.M.8
  • 17
    • 17544374351 scopus 로고    scopus 로고
    • T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3
    • DOI 10.1074/jbc.271.19.11410
    • Welsh GI, Miyamoto S, Price NT, Safer B, Proud CG. T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3. J Biol Chem 1996;271:11410-3. (Pubitemid 26155980)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.19 , pp. 11410-11413
    • Welsh, G.I.1    Miyamoto, S.2    Priced, N.T.3    Safer, B.4    Proud, C.G.5
  • 19
    • 0029964272 scopus 로고    scopus 로고
    • In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: Lack of relationship with clinical disease activity
    • Barcellini W, Rizzardi GP, Borghi MO, Nicoletti F, Fain C, Del Papa N, et al. In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: lack of relationship with clinical disease activity. Lupus 1996;5:139-45.
    • (1996) Lupus , vol.5 , pp. 139-145
    • Barcellini, W.1    Rizzardi, G.P.2    Borghi, M.O.3    Nicoletti, F.4    Fain, C.5    Del Papa, N.6
  • 20
    • 0020546709 scopus 로고
    • Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE)
    • Linker-Israeli M, Bakke AC, Kitridou RC, Gendler S, Gillis S, Horwitz DA. Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE). J Immunol 1983;130:2651-5.
    • (1983) J Immunol , vol.130 , pp. 2651-2655
    • Linker-Israeli, M.1    Bakke, A.C.2    Kitridou, R.C.3    Gendler, S.4    Gillis, S.5    Horwitz, D.A.6
  • 21
    • 0038062836 scopus 로고    scopus 로고
    • Rewiring the T-cell: Signaling defects and novel prospects for the treatment of SLE
    • Tsokos GC, Nambiar MP, Tenbrock K, Juang YT. Rewiring the T-cell: signaling defects and novel prospects for the treatment of SLE. Trends Immunol 2003;24:259-63.
    • (2003) Trends Immunol , vol.24 , pp. 259-263
    • Tsokos, G.C.1    Nambiar, M.P.2    Tenbrock, K.3    Juang, Y.T.4
  • 22
    • 31144451804 scopus 로고    scopus 로고
    • Transcriptional repression of interleukin-2 in human systemic lupus erythematosus
    • Katsiari CG, Tsokos GC. Transcriptional repression of interleukin-2 in human systemic lupus erythematosus. Autoimmun Rev 2006;5:118-21.
    • (2006) Autoimmun Rev , vol.5 , pp. 118-121
    • Katsiari, C.G.1    Tsokos, G.C.2
  • 23
    • 16844376445 scopus 로고    scopus 로고
    • Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV
    • Juang YT, Wang Y, Solomou EE, Li Y, Mawrin C, Tenbrock K, et al. Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV. J Clin Invest 2005;115:996-1005.
    • (2005) J Clin Invest , vol.115 , pp. 996-1005
    • Juang, Y.T.1    Wang, Y.2    Solomou, E.E.3    Li, Y.4    Mawrin, C.5    Tenbrock, K.6
  • 24
    • 33746992175 scopus 로고    scopus 로고
    • Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line
    • Luan HY, Tang SJ, Yang W, Tsai CY, Sun GH, Sun KH. Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line. Clin Immunol 2006;120:326-34.
    • (2006) Clin Immunol , vol.120 , pp. 326-334
    • Luan, H.Y.1    Tang, S.J.2    Yang, W.3    Tsai, C.Y.4    Sun, G.H.5    Sun, K.H.6
  • 25
    • 68849098147 scopus 로고    scopus 로고
    • Antibody-based therapies in systemic lupus erythematosus
    • Iikuni N, La Cava A. Antibody-based therapies in systemic lupus erythematosus. Mini Rev Med Chem 2009;9:829-46.
    • (2009) Mini Rev Med Chem , vol.9 , pp. 829-846
    • Iikuni, N.1    La Cava, A.2
  • 26
    • 0034094660 scopus 로고    scopus 로고
    • Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1β, IL-6, IL-8, IL-10 and TNF-α from normal human mononuclear cells involving in the lupus pathogenesis
    • Sun KH, Yu CL, Tang SJ, Sun GH. Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1β, IL-6, IL-8, IL-10 and TNF-α from normal human mononuclear cells involving in the lupus pathogenesis. Immunology 2000;99:352-60.
    • (2000) Immunology , vol.99 , pp. 352-360
    • Sun, K.H.1    Yu, C.L.2    Tang, S.J.3    Sun, G.H.4
  • 27
    • 0034894630 scopus 로고    scopus 로고
    • Monoclonal antibodies against human ribosomal P proteins penetrate into living cells and cause apoptosis of Jurkat T cells in culture
    • Oxford
    • Sun KH, Tang SJ, Lin ML, Wang YS, Sun GH, Liu WT. Monoclonal antibodies against human ribosomal P proteins penetrate into living cells and cause apoptosis of Jurkat T cells in culture. Rheumatology (Oxford) 2001;40:750-6.
    • (2001) Rheumatology , vol.40 , pp. 750-756
    • Sun, K.H.1    Tang, S.J.2    Lin, M.L.3    Wang, Y.S.4    Sun, G.H.5    Liu, W.T.6
  • 28
    • 17044365744 scopus 로고    scopus 로고
    • Monoclonal ribosomal P autoantibody inhibits the expression and release of IL-12, TNF-α and iNOS in activated RAW macrophage cell line
    • Sun KH, Tang SJ, Chen CY, Lee TP, Feng CK, Yu CL, et al. Monoclonal ribosomal P autoantibody inhibits the expression and release of IL-12, TNF-α and iNOS in activated RAW macrophage cell line. J Autoimmun 2005;24:135-43.
    • (2005) J Autoimmun , vol.24 , pp. 135-143
    • Sun, K.H.1    Tang, S.J.2    Chen, C.Y.3    Lee, T.P.4    Feng, C.K.5    Yu, C.L.6
  • 29
    • 58149345670 scopus 로고    scopus 로고
    • Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalization via electrostatic interactions
    • Song YC, Sun GH, Lee TP, Huang JC, Yu CL, Chen CH, et al. Arginines in the CDR of anti-dsDNA autoantibodies facilitate cell internalization via electrostatic interactions. Eur J Immunol 2008;38:3178-90.
    • (2008) Eur J Immunol , vol.38 , pp. 3178-3190
    • Song, Y.C.1    Sun, G.H.2    Lee, T.P.3    Huang, J.C.4    Yu, C.L.5    Chen, C.H.6
  • 30
  • 31
    • 0037243747 scopus 로고    scopus 로고
    • Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2
    • Oxford
    • Sun KH, Tang SJ, Wang YS, Lin WJ, You RI. Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2. Rheumatology (Oxford) 2003;42:154-61.
    • (2003) Rheumatology , vol.42 , pp. 154-161
    • Sun, K.H.1    Tang, S.J.2    Wang, Y.S.3    Lin, W.J.4    You, R.I.5
  • 33
    • 0032192564 scopus 로고    scopus 로고
    • Cellular penetration and nuclear localization of anti-DNA antibodies: Mechanisms, consequences, implications and applications
    • DOI 10.1006/jaut.1998.0217
    • Madaio MP, Yanase K. Cellular penetration and nuclear localization of anti-DNA antibodies: mechanisms, consequences, implications and applications. J Autoimmun 1998;11:535-8. (Pubitemid 28520212)
    • (1998) Journal of Autoimmunity , vol.11 , Issue.5 , pp. 535-538
    • Madaio, M.P.1    Yanase, K.2
  • 34
    • 1442323830 scopus 로고    scopus 로고
    • Cellular dysfunction induced by penetration of autoantibodies into living cells: Cellular damage and dysfunction mediated by antibodies to dsDNA and ribosomal P proteins
    • Putterman C. Cellular dysfunction induced by penetration of autoantibodies into living cells: cellular damage and dysfunction mediated by antibodies to dsDNA and ribosomal P proteins. Autoimmun Rev 2004;3:7-11.
    • (2004) Autoimmun Rev , vol.3 , pp. 7-11
    • Putterman, C.1
  • 35
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • Malek TR, Bayer AL. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol 2004;4:665-74.
    • (2004) Nat Rev Immunol , vol.4 , pp. 665-674
    • Malek, T.R.1    Bayer, A.L.2
  • 36
    • 33947597084 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
    • DOI 10.1007/s11064-006-9128-5
    • Jope RS, Yuskaitis CJ, Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 2007;32:577-95. (Pubitemid 46481289)
    • (2007) Neurochemical Research , vol.32 , Issue.4-5 , pp. 577-595
    • Jope, R.S.1    Yuskaitis, C.J.2    Beurel, E.3
  • 37
    • 33846921242 scopus 로고    scopus 로고
    • GSK-3 mediates differentiation and activation of proinflammatory dendritic cells
    • Rodionova E, Conzelmann M, Maraskovsky E, Hess M, Kirsch M, Giese T, et al. GSK-3 mediates differentiation and activation of proinflammatory dendritic cells. Blood 2007;109:1584-92.
    • (2007) Blood , vol.109 , pp. 1584-1592
    • Rodionova, E.1    Conzelmann, M.2    Maraskovsky, E.3    Hess, M.4    Kirsch, M.5    Giese, T.6
  • 38
    • 0027943716 scopus 로고
    • Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride
    • Hart DA, Done SJ, Benediktsson H, Lenz SP. Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride. Int J Immunopharmacol 1994;16:825-33.
    • (1994) Int J Immunopharmacol , vol.16 , pp. 825-833
    • Hart, D.A.1    Done, S.J.2    Benediktsson, H.3    Lenz, S.P.4
  • 39
    • 0029085396 scopus 로고
    • Lithium chloride enhances survival of NZB/W lupus mice: Influence of melatonin and timing of treatment
    • Lenz SP, Izui S, Benediktsson H, Hart DA. Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment. Int J Immunopharmacol 1995;17:581-92.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 581-592
    • Lenz, S.P.1    Izui, S.2    Benediktsson, H.3    Hart, D.A.4
  • 40
    • 0033755567 scopus 로고    scopus 로고
    • Molecular aberrations in human systemic lupus erythematosus
    • Tsokos GC, Kammer GM. Molecular aberrations in human systemic lupus erythematosus. Mol Med Today 2000;6:418-24.
    • (2000) Mol Med Today , vol.6 , pp. 418-424
    • Tsokos, G.C.1    Kammer, G.M.2
  • 42
    • 0029910218 scopus 로고    scopus 로고
    • Impaired recovery and cytolytic function of CD56+ T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation: Studies in unselected patients and monozygotic disease-discordant twins
    • Stohl W, Elliott JE, Hamilton AS, Deapen DM, Mack TM, Horwitz DA. Impaired recovery and cytolytic function of CD56+ T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation: studies in unselected patients and monozygotic disease-discordant twins. Arthritis Rheum 1996;39:1840-51.
    • (1996) Arthritis Rheum , vol.39 , pp. 1840-1851
    • Stohl, W.1    Elliott, J.E.2    Hamilton, A.S.3    Deapen, D.M.4    Mack, T.M.5    Horwitz, D.A.6


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