Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Frost, Jennifer M ^a,b   Udayashankar, Ramya ^c   Moore, Harry D ^c   Moore, Gudrun E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DECORIN; NUCLEOSOME ASSEMBLY PROTEIN 1; POTASSIUM CHANNEL KCNQ1; PROTEIN KCNQ1OT1; PROTEIN NAP1L4; PROTEIN OSBPL5; UNCLASSIFIED DRUG; UNTRANSLATED RNA; VOLTAGE GATED POTASSIUM CHANNEL; KCNQ1 PROTEIN, HUMAN; NAP1L4 PROTEIN, HUMAN; NUCLEAR PROTEIN; OXYSTEROL RECEPTOR; PROTEOGLYCAN; SCLEROPROTEIN; STEROID RECEPTOR;

ALLELE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CPG ISLAND; CYTOTROPHOBLAST; DNA METHYLATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EPIGENETICS; FETUS; FIRST TRIMESTER PREGNANCY; GENE EXPRESSION; GENOME IMPRINTING; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; IN VITRO STUDY; MOUSE; NONHUMAN; PLACENTA DEVELOPMENT; PLACENTAL TRANSFER; REGULATOR GENE; TELOMERE; TROPHOBLAST; UBIQUITINATION; ANIMAL; CELL CULTURE; CYTOLOGY; FEMALE; GENETICS; METABOLISM; PREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUS;

ALLELES; ANIMALS; CELLS, CULTURED; EMBRYONIC STEM CELLS; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENOMIC IMPRINTING; GENOTYPE; HUMANS; KCNQ1 POTASSIUM CHANNEL; MICE; NUCLEAR PROTEINS; PREGNANCY; PROTEOGLYCANS; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TROPHOBLASTS;

EID: 77955397863     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011595     Document Type: Article

References (19)

1. Abu-Amero S, Monk D, Frost J, Preece M, Stanier P, et al. (2008) The genetic aetiology of Silver-Russell syndrome. J Med Genet 45: 193-199.
2. Sun FL, Dean WL, Kelsey G, Allen ND, Reik W (1997) Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389: 809-815.
3. Bischof JM, Stewart CL, Wevrick R (2007) Inactivation of the mouse Magel2 gene results in growth abnormalities similar to Prader-Willi syndrome. Hum Mol Genet 16: 2713-2719.
4. Mancini-DiNardo D, Steele SJ, Ingram RS, Tilghman SM (2003) A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer. Hum Mol Genet 12: 283-294.
5. Lewis A, Mitsuya K, Umlauf D, Smith P, Dean W, et al. (2004) Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet 36: 1291-1295.
6. Umlauf D, Goto Y, Cao R, Cerqueira F, Wagschal A, et al. (2004) Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nat Genet 36: 1296-1300.
7. Mancini-DiNardo D, Steele SJ, Levorse JM, Ingram RS, Tilghman SM (2006) Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. Genes Dev 20: 1268-1282.
8. Redrup L, Branco MR, Perdeaux ER, Krueger C, Lewis A, et al. (2009) The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing. Development 136: 525-530.
9. Monk D, Arnaud P, Apostolidou S, Hills FA, Kelsey G, et al. (2006) Limited evolutionary conservation of imprinting in the human placenta. Proc Natl Acad Sci U S A 103: 6623-6628.
10. Mizuno Y, Sotomaru Y, Katsuzawa Y, Kono T, Meguro M, et al. (2002) Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray. Biochem Biophys Res Commun 290: 1499-1505.
11. Knox K, Baker JC (2008) Genomic evolution of the placenta using co-option and duplication and divergence. Genome Res 18: 695-705.
12. Schulz LC, Ezashi T, Das P, Westfall SD, Livingston KA, et al. (2008) Human embryonic stem cells as models for trophoblast differentiation. Placenta 29 Suppl A: S10-S16.
13. Moore T, Haig D (1991) Genomic imprinting in mammalian development: a parental tug-of-war. Trends Genet 7: 45-49.
14. Harun R, Ruban L, Matin M, Draper J, Jenkins NM, et al. (2006) Cytotrophoblast stem cell lines derived from human embryonic stem cells and their capacity to mimic invasive implantation events. Hum Reprod 21: 1349-1358.
15. Bock C, Reither S, Mikeska T, Paulsen M, Walter J, et al. (2005) BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics 21: 4067-4068.
16. Morison IM, Ramsay JP, Spencer HG (2005) A census of mammalian imprinting. Trends Genet 21: 457-465.
17. King A, Thomas L, Bischof P (2000) Cell culture models of trophoblast II: trophoblast cell lines-a workshop report. Placenta 21 Suppl A: S113-S119.
18. Adewumi O, Aflatoonian B, hrlund-Richter L, Amit M, Andrews PW, et al. (2007) Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol 25: 803-816.
19. Kim KP, Thurston A, Mummery C, Ward-van OD, Priddle H, et al. (2007) Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines. Genome Res 17: 1731-1742.