TNFR1 mRNA expression level and TNFR1 gene polymorphisms are predictive markers for susceptibility to develop invasive pulmonary aspergillosis

International Journal of Immunopathology and Pharmacology

Volumn 23, Issue 2, 2010, Pages 423-436

  Sainz Pérez, Juan ^a   Salas Alvarado, I ^a   Lopez Fernandez E ^a   Olmedo, C ^a   Comino, A ^a   Garcia F ^b   Blanco, A ^b   Gomez Lopera S ^a   Oyonarte, S ^c   Bueno, P ^a   Jurado, M ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

^c Blood Transfusion Centre   (Spain)

Author keywords

IPA; Susceptibility; TNFR1 genetic polymorphisms; TNFR1 messenger RNA level

Indexed keywords

GALACTOMANNAN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; MESSENGER RNA; TUMOR NECROSIS FACTOR RECEPTOR 1;

5' UNTRANSLATED REGION; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; APLASTIC ANEMIA; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; EXON; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEMATOLOGIC MALIGNANCY; HIGH RISK POPULATION; HODGKIN DISEASE; HUMAN; IMMUNOCOMPROMISED PATIENT; INFECTION RISK; INNATE IMMUNITY; LUNG ASPERGILLOSIS; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NUCLEOTIDE SEQUENCE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RISK ASSESSMENT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 77955394282     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201002300205     Document Type: Article

References (40)

1. Offner F, Cordonnier C, Ljungman P, et al. Impact of previous aspergillosis on the outcome of bone marrow transplantation. Clin Infect Dis 1998; 26:1098-1103. (Pubitemid 28215472)
2. de la Rosa GR, Champlin RE, Kontoyiannis DP. Risk factors for the development of invasive fungal infections in allogeneic blood and marrow transplant recipients. Transpl Infect Dis 2002; 4:3-9. (Pubitemid 34786819)
3. Chamilos G, Luna M, Lewis RE, Bodey GP, Chemaly R, Tarrand JJ, Safdar A, Raad II, Kontoyiannis DP. Invasive fungal infections in patients with hematologic malignancies in a tertiary care cancer center: an autopsy study over a 15-year period (1989-2003). Haematologica 2006; 91:986-9. (Pubitemid 44023159)
4. Marr KA, Carter RA, Boeckh M, Martin P, Corey L. Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors. Blood 2002; 100:4358-4366. (Pubitemid 35429674)
5. Mehrad B, Strieter RM, Standiford TJ. Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis. J Immunol 1999; 162:1633-40. (Pubitemid 29307039)
6. Luther K, Rohde M, Heesemann J, Ebel F. Quantification of phagocytosis of Aspergillus conidia by macrophages using a novel antibody-independent assay. J Microbiol Methods 2006; 66:170-173. (Pubitemid 43767533)
7. Marks JD, Marks CB, Luce JM, Montgomery AB, Jurner J, Mertz CA, Murray JF. Plasma tumor necrosis factor in patients with septic shock. Mortality rate, incidence of adult respiratory distress syndrome, and effects of methylprednisolone administration. Am Rev Respir Dis 1990; 141:94-7.
8. Tartaglia LA, Goeddel DV. Two TNF receptors. Immunol Today 1992; 13:151-3.
9. Jones SJ, Ledgerwood EC, Prins JB, Galbraith J, Johnson DR, Pober JS, Bradley JR. TNF recruits TRADD to the plasma membrane but non the trans-Golgi network, the principal subcellular location of TNF-R1. J Immunol 1999; 162:1042-8. (Pubitemid 29035432)
10. Kollias G, Douni E, Kassiotis G, Kontoyiannis D. The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Ann Rheum Dis 1999; 58(S):I32-9.
11. Cenci E, Mencacci A, Fe d'Ostiani C, Del Sero G, Mosci P, Montagnoli C, Bacci A, Romani L. Cytokine and T-helper-dependent lung mucosal immunity in mice with invasive pulmonary aspergillosis. J Infect Dis 1998; 178:1750-60.
12. Cenci E, Perito S, Enssle KH, Mosci P, Latge JP, Romani L, Bistoni F. Th1 and Th2 cytokines in mice with invasive aspergillosis. Infect Immun 1997; 65:564-70. (Pubitemid 27053226)
13. Cumberbatch M, Kimber I. Tumor necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization. Immunology 1995; 84:31-35.
14. Wu-Hsieh BA, Lee GS, Franco M, Hofman FM. Early activation of splenic macrophages by tumor necrosis factor alpha is important in determining the outcome of experimental histoplasmosis in mice. Infec Immun 1992; 60:4230-5.
15. Hehlgans T, Pfeffer K. The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games. Immunology 2005; 115:1-20. (Pubitemid 40598088)
16. Ferrante A. Tumor necrosis factor α potentiates neutrophil antimicrobial activity: increased fungal activity against Torulopsis glabrata and Candida albicans and associated increases in oxygen radical production and lysosomal enzyme release. Infect Immun 1989; 57:2115-22. (Pubitemid 19186891)
17. Nagai H, Guo J, Choi H, Kurup V. Interferon-γ and tumor necrosis factor-α protect mice from invasive aspergillosis. J Infect Dis 1995; 172:1554-60. (Pubitemid 3023470)
18. Duong M, Ouellet N, Simard M, Bergeron Y, Olivier M, Bergeron MG. Kinetic study of host defense and inflammatory response to Aspergillus fumigatus in steroid-induced immunosuppressed mice. J Infect Dis 1998; 178:1472-82. (Pubitemid 28523287)
19. Netea MG, Blok WL, Kullberg BJ, Bemelmans M, Vogels MTE, Buurman WA, Van der Meer JWM. Pharmacological inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice. J Infect Dis 1995; 171:393-9.
20. Kwiatkowski D. Science, Medicine and the future: Susceptibility to infection. Brit Med J 2000; 321:1061-5.
21. Knight JC. Regulatory polymorphisms underlying complex disease traits. J Mol Med 2005; 83:97-109.
22. Sainz J, Pérez E, Hassan L, Moratalla A, Romero A, Collado MD, Jurado M. VNTR of TNF receptor 2 promoter as genetic biomarker of susceptibility to develop Invasive Pulmonary Aspergilosis. Human Immunol 2007; 68:41-50.
23. Sainz J, Hassan L, Pérez E, Romero A, Moratalla A, López-Fernández E, Oyonarte S, Jurado M. Interleukin-10 polymorphisms as risk factor to develop Invasive Pulmonary Aspergillosis. Immunol Lett 2007; 109:76-82.
24. Sainz J, Pérez E, Gómez-Lopera S, López- Fernández E, Moratalla L, Oyonarte S, Jurado M. Genetic variants of IL6 gene promoter influence on C-reactive protein levels but are not associated with susceptibility to invasive pulmonary aspergillosis in haematological patients. Cytokine 2008; 41:268-78.
25. Sainz J, Pérez E, Gómez-Lopera S, Jurado M. IL1 gene cluster polymorphisms and its haplotypes may predict the risk to develop invasive pulmonary aspergillosis and modulate C-reactive protein level. Journal of Clinical Immunology 2008; 28:473-85.
26. Bochud PY, Chien JW, Marr KA, et al. Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation. N Engl J Med 2008; 359:1766-77.
27. Pitts SA, Olomolaiye OO, Elson CJ, Westacott CI, Bidwell JL. An MspA1 I polymorphism in exon 1 of the human TNF receptor type I (p55) gene. Eur J Immunogenet 1998; 25:269-70.
28. Waschke KA, Villani AC, Vermeire S, Dufresne L, Chen TC, Bitton A, Cohen A, Thomson AB, Wild GE. Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes. Am J Gastroenterol 2005; 100:1126-33.
29. McDermott MF, Aksentijevich I, Galon J, et al. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell 1999; 97:133-44.
30. Nishimura M, Obayashi H, Mizuta I, et al. TNF, TNF receptor type 1, and allograft inflammatory factor-1 gene polymorphisms in Japanese patients with type 1 diabetes. Human Immunol 2003; 64:302-9.
31. Ascioglu S, Rex JH, de Pauw B, et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and haematopoietic stem cell transplants: an international consensus. Clin Infect Dis 2002; 34:7-14.
32. Matys V, Kel-Margoulis OV, Fricke E, et al. TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res 2006; 34(Database issue):108-110.
33. Gupta S, Stamatoyannopoulos JA, Bailey TL, Noble WS. Quantifying similarity between motifs. Genome Biol 2007; 8:R24.1-R24.9.
34. Taniguchi T, Ogasawara K, Takaoka A, Tanaka N. IRF family of transcription factors as regulators of host defense. Annu Rev Immunol 2001; 19:623-55.
35. Kroeger KM, Carville KS, Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 1997; 34:391-9
36. Wang S, Wei M, Han Y, et al. Roles of TNF-alpha gene polymorphisms in the occurrence and progress of SARS-Cov infection: a case-control study. BMC Infect Dis 2008; 8:27-36.
37. Dror N, Alter-Koltunoff M, Azriel A, et al. Identification of IRF-8 and IRF-1 target genes in activated macrophages. Molecular Immunology 2007; 44:338-46.
38. Zhao J, Kong HJ, Li H, et al. IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFNγ Signaling Pathways. J Biol Chem 2006; 281:10073-80.
39. Tamura T, Nagamura-Inoue T, Shmeltzer Z, Kuwata T, Ozato K. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages. Immunity 2000; 13:155-65.
40. Schling P, Rudolph C, Heimerl S, Fruth S, Schmitz G. Expression of tumor necrosis factor alpha and its receptors during cellular differentiation. Cytokine 2006; 33:239-45.