Hypophosphatemia an evidence-based problem-solving approach to clinical cases

Iranian Journal of Kidney Diseases

Volumn 4, Issue 3, 2010, Pages 195-201

  Assadi, Farahnak ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Diagnosis; Fibroblast growth factor 23; Hypophosphatemia; Phosphorus metabolism disorders

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; FIBROBLAST GROWTH FACTOR 23; PHOSPHATE; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; VITAMIN D;

ARTICLE; BONE PAIN; CALCIUM BLOOD LEVEL; DIFFERENTIAL DIAGNOSIS; DRUG DOSE INCREASE; FAMILIAL HYPOPHOSPHATEMIC RICKETS; GENE MUTATION; HEART DISEASE; HUMAN; HYPOPHOSPHATEMIA; MENTAL DISEASE; MUSCLE WEAKNESS; ONCOGENIC OSTEOMALACIA; PHOSPHATE BLOOD LEVEL; PHOSPHATE EXCRETION; PRIMARY HYPERPARATHYROIDISM; PRIMARY RENAL PHOSPHATE WASTING; RECOMMENDED DRUG DOSE; RENAL PHOSPHATE WASTING; SECONDARY HYPERPARATHYROIDISM; SUPPLEMENTATION; SYMPTOM; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; X LINKED HYPOPHOSPHATEMIC RICKETS;

CALCITRIOL; EVIDENCE-BASED MEDICINE; HUMANS; HYPOPHOSPHATEMIA; PHOSPHATES; PROBLEM SOLVING; VITAMINS;

EID: 77955391417     PISSN: 17358582     EISSN: 17358604     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Weisinger JR, Bellorin-Font E. Magnesium and phosphorous. Lancet.1998;352:391-6.
2. Murer H, Hernando N, Forster I, Biber J. Proximal tubular phosphate reabsorption: molecular mechanisms. Physiol Rev. 2000;80:1373-409.
3. Knochel JP. The pathophysiology and clinical characteristics of severe hypophosphatemia. Arch Intern Med. 1977;137:203-20.
4. DiMeglio LA, White KE, Econs MJ. Disorders of phosphate metabolism. Endocrinol Metab Clin North Am. 2000;29:591-609.
5. Rubin MF, Narins RG. Hypophosphatemia: pathophysiological and practical aspects of its therapy. Semin Nephrol. 1990;10:536-45.
6. Gaasbeek A, Meinders AE. Hypophosphatemia: an update on its etiology and treatment. Am J Med. 2005;118:1094-101.
7. Assadi F. Disorders of divalent ion metabolism. In: Assadi F, editor. Clinical decisions in pediatric nephrology: a problem-solving approach to clinical cases. New York: Springer; 2008. p. 97-123.
8. Schmitt CP, Mehs O. The enigma of hyperparathyroidism in hypophosphatemic rickets. Pediatr Nephrology. 2004;19:473-7.
9. Tenenhouse HS; Murer H. Disorders of renal tubular phosphate transport. J Am Soc Nephrol. 2003;14:240-8.
10. Agus ZS, Goldfab S, Sheridan AM. Diagnosis and treatment of hypophosphatemia. In: Rose BD, editor. Uptodate. Wellesley: 2009;17 (3). [CD-ROM].
11. Jonsson KB, Zahradnik R, Larsson T, et al. Fibroblast growth factor 23 in oncogenic osteomalacia and x-linked hypophosphatemia. N Engl J Med. 2003;348:1656-63.
12. [No authors listed]. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium. Nat Genet. 1995;11:130-6.
13. ADHR Consortium. Autosomal dominant hypoposphatemic rickets is associated with mutations in FGF23. Nat Genet. 2000;26:345-8.
14. Liu PY; Jeng CY. Severe hypophosphatemia in a patient with diabetic ketoacidosis and acute respiratory failure. J Chin Med Assoc. 2004;67:355-9.
15. Paleologos M, Stone E, Braude S. Persistent, progressive hypophosphatemia after voluntary hyperventilation. Clin Sci. 2000;98:619-25.
16. Marinella MA. Refeeding syndrome and hypophosphatemia. J Intensive Care Med. 2005;20:155-9.
17. Nowack R, Wachtler P. Hypophosphatemia and hungry bone syndrome in a dialysis patient with secondary hyperparathyroidism treated with cinacalcet--proposal for an improved monitoring. Clin Lab. 2006;52:583-7.
18. Kumar R. Tumor-induced osteomalacia and the regulation of phosphate homeostasis. Bone. 2000;27:333-8.
19. Bergwitz C, Roslin NM, Tieder M, et al. SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predicts a key role in maintaining phosphate homeostasis. Am J Hum Genet. 2006;78:179-92.
20. Jaureguiberry G, Carpenter TO, Forman S, Jueppner H, Bergwitz C. A novel missense mutation in SLC34A3 that causes HHRH identifies threonine 137 as an important determinant of sodium-phosphate co-transport in NaPi-IIc. Am J Physiol Renal Phsiol. 2008;295:F371-9.
21. Planas RF, Mc Brayer RH, Koen PA. Effects of hypophosphatemia on pulmonary muscle performance. Adv Exp Med Biol. 1982;151:283-90.
22. Ravid M, Robson M. Proximal myopathy caused by iatrogenic phosphate depletion. JAMA. 1976;236:1380-9.
23. O'Connor LR, Klein KL, Bethune JE. Effect of hypophosphatemia on myocardial performance in man. N Engl J Med. 1977;297:901-3.
24. Knochell JP. Hypophosphatemia and rabdomyolysis. Am J Med. 1992;92:455-9.
25. Siddiqui MF, Bertorini TE. Hypophosphatemia-induced neuropathy: clinical and electrophysiologic findings. Muscle Nerve. 1998;21:650-2.
26. Hicks W, Hardy G. Phosphate supplementation for hypophosphatemia and parenteral nutrition. Curr Opin Clin Nutr Metab Care. 2001;4:227-33.
27. Nishida Y, Taketani Y, Yamanaka-Okumura H, Imamura F, Taniguchi A, Sato T. Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men. Kidney Int. 2006;70: 2141-7.
28. Carpenter TO. New perspectives on the biology and treatment of X-linked hypophosphatemic rickets. Pediatr Clin North Am. 1997;44:443-66.
29. Bettinelli A, Bianchi ML, Mazzucchi E. Acute effects of clacitriol and phosphate salts on mineral metabolism in children with hypophosphatemic rickets. J Pediatr. 1991;118:372-6.
30. Lentz RD, Brown DM, Kjellstrand CM. Treatment of severe hypophosphatemia. Ann Intern Med. 1978;89:941-4.
31. Subramanian R, Khardori R. Severe hypophosphatemia. Pathologic implications, clinical presentations and treatment. Medicine (Baltimore). 2000;79:1-8.
32. Perreault MM, Ostrop NJ, Tierney MG. Efficacy and safety of intravenous phosphate replacement in critically ill patient. Ann Pharmacother. 1997;31:683-8.
33. Drezner MK. Tumor-induced osteomalacia. Rev Endocr Metab Disord. 2001;2:175-86.
34. Clarke BL, Wynne AG, Wilson DM, Fitzpatrick LA. Osteomalacia associated with adult Fanconi's syndrome: Clinical and diagnostic features. Clin Endocrinol. 1995;43:479-90.
35. Tenenhouse HS. X-linked hypophosphatemia: a homologous disorder in human and mice. Nephrol Dial Transplant. 1999;14:333-41.
36. Berndt TJ, Kumar R. Phosphatonins and the regulation of phosphate homeostasis. Ann Rev Physiol. 2007;69: 341-59.
37. Wilkins GE, Granleese S, Hegele RG, et al. Oncogenic osteomalacia: Evidence for a humoral phosphaturic factor. J Clin Endocrinol Metab. 1995;80:1628-34.
38. Jan de Beur SM, Streeten EA, Civelek AC, et al. Localization of mesenchymal tumors by somatostatin receptor imaging. Lancet. 2002;359:761-3.