Individual voxel-based analysis of brain magnetization transfer maps shows great variability of gray matter injury in the first stage of multiple sclerosis

Journal of Magnetic Resonance Imaging

Volumn 32, Issue 2, 2010, Pages 424-428

  Jure, Lorena ^a   Zaaraoui, Wafaa ^a   Rousseau, Celia ^a   Reuter, Francoise ^a,b   Rico, Audrey ^a,b   Malikova, Irina ^a,b   Confort Gouny, Sylviane ^a   Cozzone, Patrick J ^a   Pelletier, Jean ^a,b   Ranjeva, Jean Philippe ^a   Audoin, Bertrand ^a,b  

^a University of Aix Marseille   (France)

^b TIMONE HOSPITAL   (France)

Author keywords

CIS; Grey matter; Individual; MRI; MTR; Multiple sclerosis

Indexed keywords

ADULT; ARTICLE; BRAIN INJURY; BRAIN MAPPING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL CORTEX; GRAY MATTER; HUMAN; LIMBIC CORTEX; MAGNETISM; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE SCANNER; OCCIPITAL CORTEX; PRIORITY JOURNAL; TEMPORAL CORTEX; VOXEL BASED MORPHOMETRY;

ADOLESCENT; ADULT; BRAIN; BRAIN MAPPING; CASE-CONTROL STUDIES; DIAGNOSTIC IMAGING; DISEASE PROGRESSION; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; REPRODUCIBILITY OF RESULTS;

EID: 77955352802     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22265     Document Type: Article

References (23)

1. Compston A, Coles A. Multiple sclerosis. Lancet 2008;372:1502-1517.
2. Geurts JJ, Barkhof F. Grey matter pathology in multiple sclerosis. Lancet Neurol 2008;7:841-851.
3. Bo L, Geurts JJ, van der Valk P, Polman C, Barkhof F. Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis. Arch Neurol 2007;64:76-80.
4. Amato MP, Portaccio E, Goretti B, et al. Association of neocortical volume changes with cognitive deterioration in relapsing-remitting multiple sclerosis. Arch Neurol 2007;64:1157-1161.
5. Kutzelnigg A, Lucchinetti CF, Stadelmann C, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005;128(Pt 11):2705-2712. (Pubitemid 41552953)
6. Bar-Zohar D, Agosta F, Goldstaub D, Filippi M. Magnetic resonance imaging metrics and their correlation with clinical outcomes in multiple sclerosis: a review of the literature and future perspectives. Mult Scler 2008;14:719-727.
7. Bakshi R, Thompson AJ, Rocca MA, et al. MRI in multiple sclerosis: current status and future prospects. Lancet Neurol 2008;7:615-625.
8. Traboulsee A, Dehmeshki J, Brex PA, et al. Normal-appearing brain tissue MTR histograms in clinically isolated syndromes suggestive of MS. Neurology 2002;59:126-128.
9. Audoin B, Au Duong MV, Ranjeva JP, et al. Magnetic resonance study of the influence of tissue damage and cortical reorganization on PASAT performance at the earliest stage of multiple sclerosis. Hum Brain Mapp 2005;24:216-228.
10. Fernando KT, Tozer DJ, Miszkiel KA, et al. Magnetization transfer histograms in clinically isolated syndromes suggestive of multiple sclerosis. Brain 2005;128(Pt 12):2911-2925.
11. Audoin B, Fernando KT, Swanton JK, Thompson AJ, Plant GT, Miller DH. Selective magnetization transfer ratio decrease in the visual cortex following optic neuritis. Brain 2006;129(Pt 4):1031-1039.
12. Audoin B, Ranjeva JP, Au Duong MV, et al. Voxel-based analysis of MTR images: a method to locate gray matter abnormalities in patients at the earliest stage of multiple sclerosis. J Magn Reson Imaging 2004;20:765-771.
13. Khaleeli Z, Cercignani M, Audoin B, Ciccarelli O, Miller DH, Thompson AJ. Localized grey matter damage in early primary progressive multiple sclerosis contributes to disability. Neuroimage 2007;37:253-261. (Pubitemid 47068988)
14. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121-127.
15. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452.
16. Ceccarelli A, Rocca MA, Pagani E, et al. A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes. Neuroimage 2008;42:315-322.
17. Henry RG, Shieh M, Okuda DT, Evangelista A, Gorno-Tempini ML, Pelletier D. Regional grey matter atrophy in clinically isolated syndromes at presentation. J Neurol Neurosurg Psychiatry 2008;79:1236-1244.
18. Dalton CM, Chard DT, Davies GR, et al. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 2004;127(Pt 5):1101-1107.
19. Bo L, Vedeler CA, Nyland HI, Trapp BD, Mork SJ. Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J Neuropathol Exp Neurol 2003;62:723-732. (Pubitemid 36870458)
20. Brownell B, Hughes JT. The distribution of plaques in the cerebrum in multiple sclerosis. J Neurol Neurosurg Psychiatry 1962;25:315-320.
21. Kutzelnigg A, Faber-Rod JC, Bauer J, et al. Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol 2007;17:38-44.
22. Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM. Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 2000;123(Pt 9):1845-1849. (Pubitemid 30664287)
23. Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM. Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis. Brain 2001;124(Pt 9):1813-1820. (Pubitemid 32845442)