Regional grey matter atrophy in clinically isolated syndromes at presentation

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 79, Issue 11, 2008, Pages 1236-1244

  Henry, Roland G ^a,b,c,d   Shieh, M ^a   Okuda, D T ^a   Evangelista, A ^a   Gorno Tempini, M L ^a   Pelletier, D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Center for Molecular and Functional Imaging   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN FUNCTION; BRAIN SIZE; CAUDATE NUCLEUS; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GRAY MATTER; GRAY MATTER ATROPHY; HUMAN; HYPOTHALAMUS; MALE; MORPHOMETRICS; PRIORITY JOURNAL; PUTAMEN; SCORING SYSTEM; THALAMUS; WHITE MATTER; ATROPHY; BRAIN; BRAIN STEM; COMPUTER ASSISTED DIAGNOSIS; MIDDLE AGED; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY;

ADULT; ATROPHY; BRAIN; BRAIN STEM; CAUDATE NUCLEUS; FEMALE; HUMANS; HYPOTHALAMUS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; PUTAMEN; THALAMUS; WALLERIAN DEGENERATION;

EID: 55249086733     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2007.134825     Document Type: Article

References (39)

1. Chard DT, Griffin CM, Parker GJ, et al. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain 2002;125:327-37.
2. Chard DT, Griffin CM, Rashid W, et al. Progressive grey matter atrophy in clinically early relapsing-remitting multiple sclerosis. Mult Scler 2004;10:387-91.
3. Calabrese M, Atzori V, Bernardi A, et al. Cortical atrophy is relevant in multiple sclerosis at clinical onset. J Neurol 2007;254:1212-20.
4. Anderson VM, Fernando KT, Davies GR, et al. Cerebral atrophy measurement in clinically isolated syndromes and relapsing remitting multiple sclerosis: a comparison of registration-based methods. J Neuroimaging 2007;17:61-8.
5. Dalton CM, Brex PA, Jenkins R, et al. Progressive ventricular enlargement in patients with clinically isolated syndromes is associated with the early development of multiple sclerosis. J Neurol Neurosurg Psychiatry 2002;73:141-7.
6. Dalton CM, Chard DT, Davies GR, et al. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 2004;127:1101-7.
7. Fernando T, Tozer DJ, Miszkiel KA, et al. Magnetization transfer histograms in clinically isolated syndromes suggestive of multiple sclerosis. Brain 2005;128:2911-25.
8. Rovaris M, Gambini A, Gallo A, et al. Axonal injury in early multiple sclerosis is irreversible and independent of the short-term disease evolution. Neurology 2005;65:1626-30.
9. Traboulsee A, Dehmeshki J, Brex PA, et al. Normal-appearing brain tissue MTR histograms in clinically isolated syndromes suggestive of MS. Neurology 2002;59:126-8.
10. Good CD, Johnsrude IS, Ashburner J, et al. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001;14:21-36.
11. Brett M, Leff AP, Rorden C, et al. Spatial normalization of brain images with focal lesions using cost function masking. Neuroimage 2001;14:486-500.
12. Garrison K, Henry R, Pelletier D. The measurement of brain atrophy in multiple sclerosis: technical aspects. In: Zivadinov R and Bakshi R, eds. Brain and Spinal Cord Atrophy in Multiple Sclerosis. Hauppauge, NY: Nova Biomedical Books, 2004:39-61.
13. Morgen K, Sammer G, Courtney SM, et al. Evidence for a direct association between cortical atrophy and cognitive impairment in relapsing-remitting MS. Neuroimage 2006;30:891-8.
14. Prinster A, Quarantelli M, Orefice G, et al. Grey matter loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study. Neuroimage 2006;29:859-67.
15. Audoin B, Davies GR, Finisku L, et al. Localization of grey matter atrophy in early RRMS: A longitudinal study. J Neurol 2006;253:1495-501.
16. Sepulcre J, Sastre-Garriga J, Cercignani M, et al. Regional gray matter atrophy in early primary progressive multiple sclerosis: a voxel-based morphometry study. Arch Neurol 2006;63:1175-80.
17. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444- 52.
18. Uitdehaag BM, Ader HJ, Roosma TJ, et al. Multiple sclerosis functional composite: impact of reference population and interpretation of changes. Mult Scler 2002;8:366-71.
19. Fischer JS, Rudick RA, Cutter GR, et al. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler 1999;5:244-50.
20. Blum D, Yonelinas AP, Luks T, et al. Dissociating perceptual and conceptual implicit memory in multiple sclerosis patients. Brain Cogn 2002;50:51-61.
21. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 2002;15:870-8.
22. Wylezinska M, Cifelli A, Jezzard P, et al. Thalamic neurodegeneration in relapsing-remitting multiple sclerosis. Neurology 2003;60:1949-54.
23. Davies GR, Altmann DR, Rashid W, et al. Emergence of thalamic magnetization transfer ratio abnormality in early relapsing-remitting multiple sclerosis. Mult Scler 2005;11:276-81.
24. Fabiano AJ, Sharma J, Weinstock-Guttman B, et al. Thalamic involvement in multiple sclerosis: a diffusion-weighted magnetic resonance imaging study. J Neuroimaging 2003;13:307-14.
25. Cifelli A, Arridge M, Jezzard P, et al. Thalamic neurodegeneration in multiple sclerosis. Ann Neurol 2002;52:650-3.
26. Houtchens MK, Benedict RH, Killiany R, et al. Thalamic atrophy and cognition in multiple sclerosis. Neurology 2007;69:1213-23.
27. Audoin B, Fernando KT, Swanton JK, et al. Selective magnetization transfer ratio decrease in the visual cortex following optic neuritis. Brain 2006;129:1031-9.
28. Geurts JJ, Reuling IE, Vrenken H, et al. MR spectroscopic evidence for thalamic and hippocampal, but not cortical, damage in multiple sclerosis. Magn Reson Med 2006;55:478-83.
29. Drayer BP, Burger P, Hurwitz B, et al. Magnetic resonance imaging in multiple sclerosis: decreased signal in thalamus and putamen. Ann Neurol 1987;22:546-50.
30. Bakshi R, Shaikh ZA, Janardhan V. MRI T2 shortening ('black T2') in multiple sclerosis: frequency, location, and clinical correlation. Neuroreport 2000;11:15-21.
31. Huitinga I, De Groot CJ, Van der Valk P, et al. Hypothalamic lesions in multiple sclerosis. J Neuropathol Exp Neurol 2001;60:1208-18.
32. Brass SD, Benedict RH, Weinstock-Guttman B, et al. Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis. Mult Scler 2006;12:437-44.
33. Glanz BI, Holland CM, Gauthier SA, et al. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Mult Scler 2007;13:1004-10.
34. Lumsden CE. The neuropathology of multiple sclerosis. In: Vinken PJ, Bruyn GW (eds). Handbook of Clinical Neurology. Vol. 9. Amsterdam: Elsevier, 1970:217-309.
35. Vercellino M, Plano F, Votta B, et al. Grey matter pathology in multiple sclerosis. J Neuropathol Exp Neurol 2005;64:1101-7.
36. Derache N, Marie RM, Constans JM, et al. Reduced thalamic and cerebellar rest metabolism in relapsing-remitting multiple sclerosis, a positron emission tomography study: correlations to lesion load. J Neurol Sci 2006;245:103-9.
37. MacKenzie-Graham A, Tinsley MR, Shah KP, et al. Cerebellar cortical atrophy in experimental autoimmune encephalomyelitis. Neuroimage 2006;32:1016-23.
38. Evangelou N, Konz D, Esiri MM, et al. Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis. Brain 2001;124:1813-20.
39. Bermel RA, Innus MD, Tjoa CW, et al. Selective caudate atrophy in multiple sclerosis: a 3D MRI parcellation study. Neuroreport 2003;14:335-9.