NIRS-measured oxy- and deoxyhemoglobin changes associated with EEG spike-and-wave discharges in a genetic model of absence epilepsy: The GAERS

Epilepsia

Volumn 51, Issue 8, 2010, Pages 1374-1384

  Roche Labarbe, Nadège ^a,b   Zaaimi, Boubker ^a   Mahmoudzadeh, Mahdi ^a   Osharina, Victoria ^a   Wallois, Alice ^a   Nehlig, Astrid ^c   Grebe, Reinhard ^a   Wallois, Fabrice ^a,b  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b University Hospital   (France)

^c INSERM   (France)

Author keywords

Absence seizures; Electroencephalography; Epilepsy; Hemodynamic changes; Near infrared spectroscopy; Rat

Indexed keywords

DEOXYHEMOGLOBIN; OXYHEMOGLOBIN; HEMOGLOBIN;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING RATE; COGNITIVE DEFECT; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; EPILEPTIC DISCHARGE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMODYNAMICS; MALE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE; ANALYSIS OF VARIANCE; ANIMAL; AUTORADIOGRAPHY; BIOLOGICAL MODEL; DISEASE MODEL; ELECTROCARDIOGRAPHY; GENETICS; HEART DISEASES; METABOLISM; PATHOPHYSIOLOGY; PLETHYSMOGRAPHY; PROCEDURES; RESPIRATION DISORDERS; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; AUTORADIOGRAPHY; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; HEART DISEASES; HEMOGLOBINS; MALE; MODELS, GENETIC; OXYHEMOGLOBINS; PLETHYSMOGRAPHY; RATS; RATS, WISTAR; RESPIRATION DISORDERS; SPECTROSCOPY, NEAR-INFRARED;

EID: 77955333545     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02574.x     Document Type: Article

References (54)

1. Aarabi A, Wallois F, Grebe R 2008) Does spatiotemporal synchronization of EEG change prior to absence seizures? Brain Res 1188:207 221.
2. Aghakhani Y, Bagshaw A, Bénar CG, Hawco C, Andermann F, Dubeau F, Gotman J 2004) fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain 127:1127 1144.
3. Bahar S, Suh M, Zhao M, Schwartz TH 2006) Intrinsic optical signal imaging of neocortical seizures: the 'epileptic dip Neuroreport 17:499 503.
4. Bartlett D, Tenney SM 1970) Control of breathing in experimental anemia. Respir Physiol 10:384 395.
5. Birn RM, Smith MA, Jones TB, Bandettini PA 2008) The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration. Neuroimage 40:644 654.
6. Bode H 1992) Intracranial blood flow velocities during seizures and generalized epileptic discharges. Eur J Pediatr 151:706 709.
7. Buchheim K, Obrig H, Pannwitz WV, Müller A, Heekeren H, Villringer A, Meierkord H 2004) Decrease in haemoglobin oxygenation during absence seizures in adult humans. Neurosci Lett 354:119 122.
8. Caplan R, Siddarth P, Stahl L, Lanphier E, Vona P, Gurbani S, Koh S, Sankar R, Shields WD 2008) Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities. Epilepsia 49:1838 1846.
9. Colonnese M, Phillips M, Constantine-Paton M, Kaila K, Jasanoff A 2008) Development of hemodynamic responses and functional connectivity in rat somatosensory cortex. Nat Neurosci 11:72 79.
10. David O, Guillemain I, Saillet S, Reyt S, Deransart C, Segebarth C, Depaulis A 2008) Identifying neural drivers with functional MRI: an electrophysiological validation. PLoS Biol, 6:e315.
11. Deransart C, Depaulis A 2002) The control of seizures by the basal ganglia? A review of experimental data Epileptic Disord 4 (suppl 3 S61 S72.
12. De Simone R, Silvestrini M, Marciana MG, Curatolo P 1997) Changes in cerebral blood flow velocities during childhood absence seizures. Pediatr Neurol 18:132 135.
13. Diehl B, Knecht S, Deppe M, Young C, Stodieck SR 1998) Cerebral hemodynamic response to generalized spike-wave discharges. Epilepsia 39:1284 1289.
14. Dufour F, Nalecz KA, Nalecz MJ, Nehlig A 2001) Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle. J Neurosci Res 66:923 930.
15. Dufour F, Koning E, Nehlig A 2003) Basal levels of metabolic activity are elevated in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): measurement of regional activity of cytochrome oxydase and lactate dehydrogenase by histochemistry. Exp Neurol 182:346 352.
16. Duong TQ 2007) Cerebral blood flow and BOLD fMRI responses to hypoxia in awake and anesthetized rats. Brain Res 1135:186 194.
17. Engel JJ, Kuhl DE, Phelps ME 1982) Patterns of human local cerebral glucose metabolism during epileptic seizures. Science 218:64 66.
18. Fantini S, Hueber DM, Franceschini MA, Gratton E, Rosenfeld W, Stubblefield PG, Maulik D, Stankovic MR 1999) Non-invasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy. Phys Med Biol 44:1543 1563.
19. Fox PT, Raichle ME 1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci USA 83:1140 1144.
20. Franceschini MA, Fantini S, Walker SA, Maier JS, Mantulin WW, Gratton E 1995) Multi-channel optical instrument for near-infrared imaging of tissue. SPIE Biomedical Optics. SPIE, San Jose, CA, USA, pp. 264 273.
21. Franceschini MA, Nissilä I, Wu W, Diamond SG, Bonmassar G, Boas DA 2008) Coupling between somatosensory evoked potentials and hemodynamic response in the rat. Neuroimage 41:189 203.
22. Haginoya K, Munakata M, Kato R, Yokoyama H, Ishizuka M, Iinuma K 2002) Ictal cerebral hemodynamics of childhood epilepsy measured with near-infrared spectrophotometry. Brain 125:1960 1971.
23. Hirsch E, Andermann F, Chauvel P, Engel J, Lopes da Silva F, Luders H 2006) Generalized Seizures: From Clinical Phenomenology to Underlying Systems and Networks. John Libbey Eurotext, UK.
24. Inouye T, Iyama A, Shinosaki K, Toi S, Matsumoto Y 1995) Inter-site EEG relationships before widespread epileptiform discharges. Int J Neurosci 82:143 153.
25. Jöbsis FF 1977) Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 198:1264 1267.
26. Kapucu LO, Serdaroglu A, Okuyaz C, Kose G, Gucuyener K 2003) Brain single photon emission computed tomographic evaluation of patients with childhood absence epilepsy. J Child Neurol 18:542 548.
27. Laufs H, Lengler U, Hamandi K, Kleinschmidt A, Krakow K 2006) Linking generalized spike-and-wave discharges and resting state brain activity by using EEGfMRI in a patient with absence seizures. Epilepsia 47:444 448.
28. Le Van Quyen M, Navarro V, Martinerie J, Baulac M, Varela F 2003) Toward a neurodynamical understanding of ictogenesis. Epilepsia 44:30 43.
29. Marescaux C, Vergnes M, Depaulis M 1992) Genetic absence epilepsy in rats from Strasbourg - a review. J Neural Transm Suppl 35:37 69.
30. Martin C, Martindale J, Berwick J, Mayhew JE 2006) Investigating neural-hemodynamic coupling and the hemodynamic response function in the awake rat. Neuroimage 32:33 48.
31. Meeren HK, Pijn JP, Van Luijtelaar EL, Coenen AM, Lopes da Silva FH 2002) Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. J Neurosci 22:1480 1495.
32. Meeren H, van Luijtelaar G, Lopes da Silva F, Coenen A 2005) Evolving concepts on the pathophysiology of absence seizures: the cortical focus theory. Arch Neurol 62:371 376.
33. Moeller F, Siebner HR, Wolff S, Muhle H, Granert O, Jansen O, Stephani U, Siniatchkin M 2008) Simultaneous EEG-fMRI in drug-naive children with newly diagnosed absence epilepsy. Epilepsia 49:1510 1519.
34. Nehlig A, Vergnes M, Marescaux C, Boyet S, Lannes B 1991) Local cerebral glucose utilization in rats with petit mal-like seizures. Ann Neurol 29:72 77.
35. Nehlig A, Vergnes M, Marescaux C, Boyet S 1992) Mapping of cerebral energy metabolism in rats with genetic generalized nonconvulsive epilepsy. J Neural Transm Suppl 35:141 153.
36. Nehlig A, Vergnes M, Marescaux C, Boyet S 1993) Cerebral energy metabolism in rats with genetic absence epilepsy is not correlated with the pharmacological increase or suppression of spike-wave discharges. Brain Res 618:1 8.
37. Nehlig A, Vergnes M, Waydelich R, Hirsh E, Charbonne R, Marescaux C, Seylaz J 1996) Absence seizures induce a decrease in cerebral blood flow: human and animal data. J Cereb Blood F Met 16:147 155.
38. Nehlig A, Vergnes M, Boyet S, Marescaux C 1998a) Local cerebral glucose utilization in adult and immature GAERS. Epilepsy Res 32:206 212.
39. Nehlig A, Vergnes M, Boyet S, Marescaux C 1998b) Metabolic activity is increased in discrete brain regions before the occurrence of spike-and-wave discharges in weanling rats with genetic absence epilepsy. Brain Res Dev Brain Res 108:69 75.
40. Nehlig A, Valenti M-P, Thiriaux A, Hirsh E, Marescaux C, Namer IJ 2004) Ictal and interictal perfusion variations measured by SISCOM analysis in typical childhood absence seizures. Epileptic Disord 6:247 253.
41. Niedermeyer E, Fineyre F, Riley T, Uematsu S 1979) Absence status (petit mal status) with focal characteristics. Arch Neurol 36:417 421.
42. O'Regan ME, Brown JK 2005) Abnormalities in cardiac and respiratory function observed during seizures in childhood. Dev Med Child Neurol, 47:4 9.
43. Osharina V, Ponchel E, Aarabi A, Grebe R, Wallois F 2010) Local haemodynamic changes preceding interictal spikes: a simultaneous electrocorticography (ECoG) and near-infrared spectroscopy (NIRS) analysis in rats. Neuroimage 50:600 607.
44. Patterson MS, Andersson-Engels S, Wilson BC, Osei EK 1995) Absorption spectroscopy in tissue-simulating materials: a theoretical and experimental study of photon paths. Appl Opt 34:22 30.
45. Planche D, Bianchi AL, Dussardier M 1970) Cortical control of respiration: study at the level of the bulbar neurons. J Physiol 62:430 431.
46. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL 2001) A default mode of brain function. Proc Natl Acad Sci USA 98:676 682.
47. Roche-Labarbe N, Zaaimi B, Berquin P, Nehlig A, Grebe R, Wallois F 2008) NIRS-measured oxy- and deoxy-hemoglobin changes associated with EEG spike-and-wave discharges in children. Epilepsia 49:1871 1880.
48. Salek-Haddadi A, Lemieux L, Merschhemke M, Friston KJ, Duncan JS, Fish DR 2003) Functional magnetic resonance imaging of human absence seizures. Ann Neurol 53:663 667.
49. Sanada S, Murakami N, Ohtahara S 1988) Changes in blood flow of the middle cerebral artery during absence seizures. Pediatr Neurol 4:158 161.
50. Schroeter ML, Kupka T, Mildner T, Uludag K, von Cramon DY 2006) Investigating the post-stimulus undershoot of the BOLD signal - A simultaneous fMRI and fNIRS study. Neuroimage 30:349 358.
51. Tan HO, Reid CA, Single FN, Davies PJ, Chiu C, Murphy S, Clarke AL, Dibbens L, Krestel H, Mulley JC, Jones MV, Seeburg PH, Sakmann B, Berkovic SF, Sprengel R, Petrou S 2007) Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy. PNAS 104:17536 17541.
52. Tenney JR, Duong TQ, King JA, Ferris CF 2004) fMRI of brain activation in a genetic rat model of absence seizures. Epilepsia 45:576 582.
53. Theodore WH, Brooks R, Margolin R, Patronas N, Sato S, Porter RJ, Mansi L, Bairamian D, DiChiro G 1985) Positron emission tomography in generalized seizures. Neurology 35:684 690.
54. Zaaimi B, Héberlé C, Berquin P, Pruvost M, Grebe R, Wallois F 2005) Vagus Nerve Stimulation Induces Concomitant Respiratory Alterations and a Decrease in SaO2 in Children. Epilepsia 46:1802 1809.